penicillin g has been researched along with Cardiotoxicity in 1 studies
Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.
Cardiotoxicity: Damage to the HEART or its function secondary to exposure to toxic substances such as drugs used in CHEMOTHERAPY; IMMUNOTHERAPY; or RADIATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cardiotoxicity is one of the most significant reasons of attrition in drug development." | 1.51 | Disruption of mitochondrial membrane potential coupled with alterations in cardiac biomarker expression as early cardiotoxic signatures in human ES cell-derived cardiac cells. ( Jyoti, S; Tandon, S, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jyoti, S | 1 |
| Tandon, S | 1 |
1 other study available for penicillin g and Cardiotoxicity
| Article | Year |
|---|---|
Disruption of mitochondrial membrane potential coupled with alterations in cardiac biomarker expression as early cardiotoxic signatures in human ES cell-derived cardiac cells.
Topics: Biomarkers; Cardiotoxicity; Cell Line; Cell Survival; Doxorubicin; Homeobox Protein Nkx-2.5; Humans; | 2019 |