Page last updated: 2024-11-07

penicillin g and Bone Fractures

penicillin g has been researched along with Bone Fractures in 8 studies

Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19908 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ORLICH, JL1
Bergman, BR2
Kondo, S3
Marumo, M2
Takeda, K2
Kojima, S2
Kunishima, I2
Buchholz, HW1
Engelbrecht, H1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Control Trial of Vancomycin Powder Following Posterior Instrumented Spinal Surgery for Trauma[NCT01977989]Phase 4140 participants (Anticipated)Interventional2013-10-31Enrolling by invitation
Application of Antibiotic Loaded Calcium Sulfate as Prophylaxis for Patients With Non Modifiable Risk Factors for Periprosthetic Joint Infections[NCT03976466]Phase 487 participants (Actual)Interventional2019-05-22Completed
Comparative Effectiveness and Cost-Benefit Analysis of Vancomycin Powder in High Risk Spine Surgery Patients[NCT01566422]0 participants (Actual)Interventional2012-06-30Withdrawn (stopped due to unable to enroll any participants)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Length of Stay as an Indicator of the Hospital Economic Burden

The length of stay is an important indicator of efficiency and hospital economic burden. The reduction in number of hospitalization days results in lower risk of infection and less medication side effects and decreased need of hospital supplies. The difference in the average days of hospitalization between both groups indirectly represents the economic cost spent by the hospital. (NCT03976466)
Timeframe: Surgical procedure day to hospital discharge.

InterventionDays (Mean)
Control Group15.25
Calcium Sulfate Study Group4.6

Trials

2 trials available for penicillin g and Bone Fractures

ArticleYear
Antibiotic prophylaxis in open and closed fractures: a controlled clinical trial.
    Acta orthopaedica Scandinavica, 1982, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Dicloxacillin; Female; Fractures, Bone; Fractures, C

1982
Concentration of dicloxacillin and benzylpenicillin in fracture haematoma.
    Scandinavian journal of infectious diseases, 1979, Volume: 11, Issue:3

    Topics: Adult; Aged; Ankle Injuries; Clinical Trials as Topic; Dicloxacillin; Double-Blind Method; Female; F

1979

Other Studies

6 other studies available for penicillin g and Bone Fractures

ArticleYear
[THE USE OF ANTIBIOTICS IN ASEPTIC SURGERY].
    Revista medica de Costa Rica, 1963, Volume: 20

    Topics: Anti-Bacterial Agents; Antisepsis; Child; Chloramphenicol; Ethylenediamines; Fractures, Bone; Humans

1963
Experimental studies on the chemotherapy of open fractures. 9. Clinical studies on the distribution of cephalosporin C antibiotics and penicillin G concentrations into human bone marrow and bone marrow bleeding.
    Bulletin of the Osaka Medical School, 1973, Volume: 19, Issue:1

    Topics: Adult; Bone Marrow; Bone Marrow Diseases; Cephalosporins; Female; Fractures, Bone; Hematoma; Humans;

1973
Experimental studies on the chemotherapy of open fractures. 10. Clinical studies on the concentrations of cephalosporin C antibiotics and penicillin G, locally administered into human bone marrow hematomas.
    Bulletin of the Osaka Medical School, 1973, Volume: 19, Issue:1

    Topics: Adult; Bone Marrow Diseases; Cephalosporins; Female; Fractures, Bone; Hematoma; Humans; Male; Middle

1973
Experimental studies on the chemotherapy of open fractures. (11). Experimental studies on cephalosporin C antibiotics and penicillin G concentrations in the bone marrow and in the fracture hematomas, after intramuscular and local administration.
    Bulletin of the Osaka Medical School, 1973, Volume: 19, Issue:2

    Topics: Animals; Bone Marrow; Cephalosporins; Fractures, Bone; Fractures, Open; Hematoma; Injections; Inject

1973
[What is your diagnosis?].
    Medizinische Klinik, 1971, Nov-05, Volume: 66, Issue:45

    Topics: Adult; Amputation, Surgical; Blood Transfusion; Chloramphenicol; Female; Forearm Injuries; Fractures

1971
[Depot effects of various antibiotics mixed with Palacos resins].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1970, Volume: 41, Issue:11

    Topics: Acrylic Resins; Adsorption; Anti-Bacterial Agents; Delayed-Action Preparations; Drug Compounding; Dr

1970
[Depot effects of various antibiotics mixed with Palacos resins].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1970, Volume: 41, Issue:11

    Topics: Acrylic Resins; Adsorption; Anti-Bacterial Agents; Delayed-Action Preparations; Drug Compounding; Dr

1970
[Depot effects of various antibiotics mixed with Palacos resins].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1970, Volume: 41, Issue:11

    Topics: Acrylic Resins; Adsorption; Anti-Bacterial Agents; Delayed-Action Preparations; Drug Compounding; Dr

1970
[Depot effects of various antibiotics mixed with Palacos resins].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1970, Volume: 41, Issue:11

    Topics: Acrylic Resins; Adsorption; Anti-Bacterial Agents; Delayed-Action Preparations; Drug Compounding; Dr

1970
[Depot effects of various antibiotics mixed with Palacos resins].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1970, Volume: 41, Issue:11

    Topics: Acrylic Resins; Adsorption; Anti-Bacterial Agents; Delayed-Action Preparations; Drug Compounding; Dr

1970
[Depot effects of various antibiotics mixed with Palacos resins].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1970, Volume: 41, Issue:11

    Topics: Acrylic Resins; Adsorption; Anti-Bacterial Agents; Delayed-Action Preparations; Drug Compounding; Dr

1970
[Depot effects of various antibiotics mixed with Palacos resins].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1970, Volume: 41, Issue:11

    Topics: Acrylic Resins; Adsorption; Anti-Bacterial Agents; Delayed-Action Preparations; Drug Compounding; Dr

1970
[Depot effects of various antibiotics mixed with Palacos resins].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1970, Volume: 41, Issue:11

    Topics: Acrylic Resins; Adsorption; Anti-Bacterial Agents; Delayed-Action Preparations; Drug Compounding; Dr

1970
[Depot effects of various antibiotics mixed with Palacos resins].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1970, Volume: 41, Issue:11

    Topics: Acrylic Resins; Adsorption; Anti-Bacterial Agents; Delayed-Action Preparations; Drug Compounding; Dr

1970