penicillin g has been researched along with Amyotrophic Lateral Sclerosis in 4 studies
Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Secondary outcomes were lung function, muscle strength, plasma creatinine, clinical stage, gastrostomy placement, quality of life and occurrence of adverse of events." | 2.94 | A placebo-controlled trial to investigate the safety and efficacy of Penicillin G/Hydrocortisone in patients with ALS (PHALS trial). ( Bunte, TM; Van Den Berg, LH; Van Eijk, RPA; Van Es, MA, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Van Es, MA | 1 |
| Van Eijk, RPA | 1 |
| Bunte, TM | 1 |
| Van Den Berg, LH | 1 |
| Bedlack, R | 1 |
| Hänsel, Y | 1 |
| Ackerl, M | 1 |
| Stanek, G | 1 |
| el Alaoui-Faris, M | 1 |
| Medejel, A | 1 |
| al Zemmouri, K | 1 |
| Yahyaoui, M | 1 |
| Chkili, T | 1 |
2 reviews available for penicillin g and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
ALSUntangled 46: penicillin G/hydrocortisone.
Topics: Amyotrophic Lateral Sclerosis; Anti-Bacterial Agents; Anti-Inflammatory Agents; Drug Therapy, Combin | 2019 |
[Amyotrophic lateral sclerosis syndrome of syphilitic origin. 5 cases].
Topics: Adult; Amyotrophic Lateral Sclerosis; Cerebrospinal Fluid; Cerebrospinal Fluid Proteins; Female; Fol | 1990 |
1 trial available for penicillin g and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
A placebo-controlled trial to investigate the safety and efficacy of Penicillin G/Hydrocortisone in patients with ALS (PHALS trial).
Topics: Amyotrophic Lateral Sclerosis; Double-Blind Method; Humans; Hydrocortisone; Penicillin G; Quality of | 2020 |
1 other study available for penicillin g and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
[ALS-like sequelae in chronic neuroborreliosis].
Topics: Amyotrophic Lateral Sclerosis; Antibodies, Bacterial; Borrelia burgdorferi Group; Chronic Disease; D | 1995 |