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penicillin g and Agranulocytosis

penicillin g has been researched along with Agranulocytosis in 24 studies

Penicillin G: A penicillin derivative commonly used in the form of its sodium or potassium salts in the treatment of a variety of infections. It is effective against most gram-positive bacteria and against gram-negative cocci. It has also been used as an experimental convulsant because of its actions on GAMMA-AMINOBUTYRIC ACID mediated synaptic transmission.
benzylpenicillin : A penicillin in which the substituent at position 6 of the penam ring is a phenylacetamido group.

Agranulocytosis: A decrease in the number of GRANULOCYTES; (BASOPHILS; EOSINOPHILS; and NEUTROPHILS).

Research Excerpts

ExcerptRelevanceReference
"Between March 1978 and March 1983 ninety-four episodes of fever in 56 mainly granulocytopenic patients with cancer were treated empirically with a combination of sulbenicillin (5."3.66[Sulbenicillin and amikacin for febrile patients with cancer--with special reference to granulocytopenia]. ( Hattori, M; Honda, T; Sampi, K, 1983)
"A 31-year-old white man with suspected aspiration pneumonia complicated by multiple pulmonary abscesses had profound neutropenia during a course of high-dose benzylpenicillin therapy for suspected bacterial endocarditis."1.27Profound neutropenia associated with benzylpenicillin. ( Bodensteiner, DC; Davis, JW; Helzberg, JH; Hodges, GR; Plapp, FV; Snavely, SR, 1983)
"Neutropenia is a potentially serious complication of parenteral benzylpenicillin administration."1.27Benzylpenicillin-induced neutropenia. ( Al-Hadramy, MS; Aman, H; Khan, MA; Omer, A, 1986)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199020 (83.33)18.7374
1990's3 (12.50)18.2507
2000's0 (0.00)29.6817
2010's1 (4.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Figueira-Coelho, J1
Pereira, O1
Picado, B1
Mendonça, P1
Neves-Costa, J1
Snavely, SR1
Helzberg, JH1
Bodensteiner, DC1
Plapp, FV1
Davis, JW1
Hodges, GR1
Sampi, K1
Honda, T1
Hattori, M1
Font, J1
Coca, A1
Goday, A1
Ingelmo, M1
Balcells, A1
Lens, XM1
Ginés, P1
Sánchez-Tapias, JM1
Murphy, MF1
Riordan, T1
Minchinton, RM1
Chapman, JF1
Amess, JA1
Shaw, EJ1
Waters, AH1
Timmis, AD1
Crofts, MA1
Metcalfe, J1
Monaghan, MJ1
Sharp, J1
Jackson, G1
Postelnick, M1
Gaskins, JD1
Neftel, KA1
Wälti, M1
Spengler, H1
von Felten, A1
Weitzman, SA1
Bürgi, H1
de Weck, AL1
Patton, WN1
Holyoake, TL1
Yates, JM1
Boughton, BJ1
Franklin, IM1
Guiot, HF1
van der Meer, JW1
van den Broek, PJ1
Willemze, R1
van Furth, R2
Olaison, L1
Alestig, K1
Kelsey, SM1
Wood, ME1
Shaw, E1
Newland, AC1
Hoogeterp, JJ1
Mattie, H1
Krul, AM1
Terporten, P1
Walz, B1
Zupnick, J1
Uden, D1
Keating, A1
Pérez, I1
Fardella, C1
Prat, G1
Chamorro, G1
Casanegra, P1
Noguera, H1
Chaimongkol, B1
Nanthachit, N1
Thongprasert, S1
Navarawong, V1
Al-Hadramy, MS1
Aman, H1
Omer, A1
Khan, MA1
Blázquez Cabrera, JA1
Sala Sánchez-Castillo, A1
García Moreno, LM1
de Castro del Pozo, S1
Tattersall, MH1
Spiers, AS1
Darrell, JH1
Abendroth, K1
Müller, W1
Warrell, DA1
Perine, PL1
Bryceson, AD1
Parry, EH1
Pope, HM1
Huenbner, RA1
Forshaw, J1

Trials

2 trials available for penicillin g and Agranulocytosis

ArticleYear
Prevention of viridans-group streptococcal septicemia in oncohematologic patients: a controlled comparative study on the effect of penicillin G and cotrimoxazole.
    Annals of hematology, 1992, Volume: 64, Issue:6

    Topics: Agranulocytosis; Antineoplastic Agents; Bacteremia; Drug Hypersensitivity; Drug Interactions; Drug R

1992
Intravenous ciprofloxacin as empirical treatment of febrile neutropenic patients.
    The American journal of medicine, 1989, Nov-30, Volume: 87, Issue:5A

    Topics: Adult; Agranulocytosis; Bacteria; Bacterial Infections; Ciprofloxacin; Drug Therapy, Combination; Fe

1989

Other Studies

22 other studies available for penicillin g and Agranulocytosis

ArticleYear
The use of granulocyte colony-stimulating factor does not appear to reduce recovery time in penicillin-related agranulocytosis during the treatment of endocarditis.
    The Journal of heart valve disease, 2010, Volume: 19, Issue:6

    Topics: Agranulocytosis; Anti-Bacterial Agents; Drug Therapy, Combination; Endocarditis, Bacterial; Female;

2010
Profound neutropenia associated with benzylpenicillin.
    Southern medical journal, 1983, Volume: 76, Issue:10

    Topics: Adult; Agranulocytosis; Endocarditis, Bacterial; Humans; Lung Abscess; Male; Neutropenia; Penicillin

1983
[Sulbenicillin and amikacin for febrile patients with cancer--with special reference to granulocytopenia].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1983, Volume: 10, Issue:11

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Amikacin; Drug Therapy, Combination; Female; Fever; Humans

1983
[Granulocytopenia caused by sodium penicillin G].
    Medicina clinica, 1983, Oct-08, Volume: 81, Issue:10

    Topics: Agranulocytosis; Empyema; Female; Humans; Middle Aged; Penicillin G

1983
[Neutropenia caused by penicillin].
    Medicina clinica, 1984, May-05, Volume: 82, Issue:17

    Topics: Adult; Agranulocytosis; Humans; Male; Neutropenia; Penicillin G

1984
Demonstration of an immune-mediated mechanism of penicillin-induced neutropenia and thrombocytopenia.
    British journal of haematology, 1983, Volume: 55, Issue:1

    Topics: Adult; Agranulocytosis; Autoantibodies; Autoimmune Diseases; Blood Cell Count; Blood Platelets; Fema

1983
Gonococcal endocarditis with penicillin-induced bone marrow hypoplasia. Role of echocardiography.
    JAMA, 1981, Aug-07, Volume: 246, Issue:6

    Topics: Adolescent; Agranulocytosis; Bone Marrow; Cefuroxime; Echocardiography; Endocarditis, Bacterial; Fem

1981
Penicillin G-induced granulocytopenia.
    Drug intelligence & clinical pharmacy, 1981, Volume: 15, Issue:4

    Topics: Adult; Agranulocytosis; Female; Humans; Penicillin G

1981
Neutropenia after penicillins: toxic or immune-mediated?
    Klinische Wochenschrift, 1981, Aug-17, Volume: 59, Issue:16

    Topics: Adolescent; Adult; Agranulocytosis; Antibodies; Dose-Response Relationship, Drug; Female; Humans; Im

1981
Accelerated recovery from drug-induced agranulocytosis following G-CSF therapy.
    British journal of haematology, 1992, Volume: 80, Issue:4

    Topics: Aged; Agranulocytosis; Captopril; Female; Granulocyte Colony-Stimulating Factor; Humans; Male; Middl

1992
A prospective study of neutropenia induced by high doses of beta-lactam antibiotics.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 25, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Agranulocytosis; Ampicillin; Anti-Bacterial Agents; Cloxacillin; Dos

1990
Comparison of in vivo and in vitro activities of antibiotics with different modes of action against a tolerant and a non-tolerant Staphylococcus aureus strain.
    Scandinavian journal of infectious diseases, 1989, Volume: 21, Issue:1

    Topics: Agranulocytosis; Animals; Ciprofloxacin; Drug Resistance, Microbial; Erythromycin; Mice; Penicillin

1989
Penicillin-induced agranulocytosis.
    The Western journal of medicine, 1988, Volume: 149, Issue:4

    Topics: Adolescent; Agranulocytosis; Endocarditis, Bacterial; Female; Humans; Penicillin G; Streptococcal In

1988
[Neutropenia induced by penicillin].
    Revista medica de Chile, 1987, Volume: 115, Issue:3

    Topics: Adult; Agranulocytosis; Endocarditis, Bacterial; Humans; Leukocyte Count; Male; Neutropenia; Penicil

1987
Penicillin-G induced granulocytopenia.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 1987, Volume: 70, Issue:7

    Topics: Adult; Agranulocytosis; Empyema; Humans; Male; Penicillin G

1987
Benzylpenicillin-induced neutropenia.
    The Journal of antimicrobial chemotherapy, 1986, Volume: 17, Issue:2

    Topics: Adolescent; Agranulocytosis; Endocarditis, Bacterial; Female; Humans; Male; Middle Aged; Neutropenia

1986
[Neutropenia caused by penicillin].
    Revista clinica espanola, 1986, Volume: 179, Issue:2

    Topics: Agranulocytosis; Female; Humans; Middle Aged; Neutropenia; Penicillin G

1986
Initial therapy with combination of five antibiotics in febrile patients with leukaemia and neutropenia.
    Lancet (London, England), 1972, Jan-22, Volume: 1, Issue:7743

    Topics: Administration, Oral; Agranulocytosis; Anemia, Aplastic; Anti-Bacterial Agents; Bacterial Infections

1972
[Therapeutic conclusions from the immunologic events in agranulocytosis].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1972, Sep-01, Volume: 27, Issue:17

    Topics: Adult; Aged; Agranulocytosis; Ampicillin; Antifungal Agents; Barbiturates; Blood Transfusion; Bone M

1972
Physiologic changes during the Jarisch-Herxheimer reaction in early syphilis. A comparison with louse-borne relapsing fever.
    The American journal of medicine, 1971, Volume: 51, Issue:2

    Topics: Adult; Agranulocytosis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Body Temperature; Cardiac

1971
Therapeutic serum concentrations of penicillin.
    Journal of the American Veterinary Medical Association, 1971, Sep-15, Volume: 159, Issue:6

    Topics: Agranulocytosis; Animals; Blood Bactericidal Activity; Corynebacterium; Fever; Immunity, Active; Inf

1971
Penicillin-induced granulopenia.
    British medical journal, 1968, Jul-20, Volume: 3, Issue:5611

    Topics: Agranulocytosis; Erythromycin; Humans; Leukocyte Count; Male; Middle Aged; Penicillin G

1968