penicillic-acid and Kidney-Diseases

penicillic-acid has been researched along with Kidney-Diseases* in 4 studies

Reviews

1 review(s) available for penicillic-acid and Kidney-Diseases

ArticleYear
Mycotoxins of possible importance in diseases of Canadian farm animals.
    The Canadian veterinary journal = La revue veterinaire canadienne, 1975, Volume: 16, Issue:5

    Topics: Aflatoxins; Animals; Animals, Domestic; Canada; Cattle; Cattle Diseases; Chickens; Citrinin; Female; Fetal Death; Kidney Diseases; Male; Mycotoxins; Ochratoxins; Patulin; Penicillic Acid; Poultry Diseases; Pregnancy; Sheep; Sheep Diseases; Swine; Swine Diseases; Trichothecenes; Vulvovaginitis; Zearalenone

1975

Other Studies

3 other study(ies) available for penicillic-acid and Kidney-Diseases

ArticleYear
Mycotoxic nephropathy in Bulgarian pigs and chickens: complex aetiology and similarity to Balkan endemic nephropathy.
    Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2010, Volume: 27, Issue:1

    Spontaneous nephropathy in Bulgaria, which is observed frequently during meat inspection and which differs morphologically from the classical description of mycotoxic porcine/chicken nephropathy as made in Denmark, was found to have a multi-mycotoxic aetiology being mainly provoked by a combined effect of ochratoxin A, penicillic acid and fumonisin B1 in addition to a not-yet-known metabolite. Mean contamination levels of ochratoxin A were consecutively low (188.8 and 376.4 microg kg(-1)) in contrast to high contamination levels of fumonisin B1 (5564.1 and 3254.5 microg kg(-1)) and penicillic acid (838.6 and 904.9 microg kg(-1)) for 2006 and 2007, respectively. Some other mycotoxins with lower importance such as citrinin, penitrem A, etc., may also influence clinicopathological picture of this nephropathy. A heavy contamination with Gibberella fujikuroi var. moniliformis (Fusarium verticillioides) and Penicillium aurantiogriseum complex (mainly Penicillium polonicum) was observed in almost all examined feed samples coming from pig and chick farms with nephropathy problems from Bulgaria. In contrast, low contamination with Aspergillus ochraceus, Penicillium verrucosum and Penicillium citrinum was observed in the same feed samples and these species were isolated as very rare components of the mycobiota.

    Topics: Animal Feed; Animals; Balkan Nephropathy; Bulgaria; Chickens; Drug Synergism; Food Contamination; Food Microbiology; Fumonisins; Humans; Kidney Diseases; Mycotoxicosis; Mycotoxins; Ochratoxins; Penicillic Acid; Poultry Diseases; Sus scrofa; Swine; Swine Diseases

2010
Experimental mycotoxic nephropathy in pigs provoked by a diet containing ochratoxin A and penicillic acid.
    Veterinary research communications, 2001, Volume: 25, Issue:3

    Mycotoxic nephropathy was induced in 18 young pigs by diets contaminated with strains of Aspergillus ochraceus containing ochratoxin A (OTA) and penicillic acid (PA) at levels corresponding to those naturally encountered in animal feeds in Bulgaria. Haematological and biochemical parameters, as well as the morphological and ultrastructural changes in various internal organs, and especially in the kidneys, were examined at different stages of development of the disease. A mottled surface of the kidneys was only seen in pigs exposed to a mouldy diet containing 180 ppb OTA for 3 months, but microscopic lesions, as well as changes in various haematological and biochemical parameters, were observed in all groups exposed to the same mouldy diet containing only 90 or 180 ppb OTA. Histological examination showed two types of change: degenerative changes affecting the epithelial cells of the proximal tubules, which predominated at the initial stage, and proliferative changes in the interstitium, which predominated at the later stage of the disease. Telangiectasis and lymph stasis were also seen, as well as degenerative changes in the capillary endothelium. The characteristic renal lesions were similar to those observed in spontaneous cases of mycotoxic porcine nephropathy in Bulgaria, but they were a little different from the classic Danish porcine nephropathy. The enhanced toxicity of OTA in our study may be due to a synergistic effect between OTA and PA or to some other unknown metabolites produced by the same ochratoxinogenic strains of A. ochraceus.

    Topics: Animal Feed; Animals; Aspergillus ochraceus; Bulgaria; Female; Histocytochemistry; Kidney; Kidney Diseases; Male; Microscopy, Electron; Mycoses; Mycotoxins; Ochratoxins; Penicillic Acid; Specific Pathogen-Free Organisms; Statistics, Nonparametric; Swine; Swine Diseases

2001
Mycotoxic diseases produced in mice by species of the Aspergillus ochraceus group.
    Food and cosmetics toxicology, 1977, Volume: 15, Issue:5

    Topics: Animals; Aspergillus; Chemical and Drug Induced Liver Injury; Female; Kidney Diseases; Liver Diseases; Male; Mice; Mycotoxins; Ochratoxins; Penicillic Acid

1977