penicillamine has been researched along with Synovitis in 15 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Synovitis: Inflammation of the SYNOVIAL MEMBRANE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have described three patients whose rheumatoid arthritis was exacerbated by penicillamine." | 7.67 | Penicillamine-induced exacerbation of rheumatoid arthritis. ( Butler, D; Tiliakos, NA, 1986) |
| " D-penicillamine, a drug effective in the proliferative synovitis of rheumatoid arthritis, was evaluated in a rabbit model of hemarthroses-induced arthritis and in four hemophiliacs with chronic synovitis." | 7.67 | Treatment of hemophilic arthritis with D-penicillamine: a preliminary report. ( Corrigan, JJ; Damiano, ML; Gall, EP; Jeter, M; Kolba, KS; Meredith, K; Trombley, J, 1985) |
| "In a double blind trial of 36 patients with rheumatoid arthritis a new scintimetric method was applied to three comparable patient groups before and after eight months' treatment with levamisole, penicillamine, or azathioprine." | 5.06 | Scintimetric assessment of synovitis activity during treatment with disease modifying antirheumatic drugs. ( Bentzon, MW; Halberg, P; Halskov, O; Olsen, N, 1988) |
| "A longitudinal study of changes in rheumatoid factor levels and their correlations with other clinical and laboratory assessment of disease activity followed 45 rheumatoid arthritis patients during 12 months continuous therapy with gold and penicillamine." | 3.67 | ELISA assays for IgM and IgG rheumatoid factors: their clinical correlations during therapy with slow-acting anti-rheumatic drugs. ( Collins, M; Dawes, PT; Scott, DL; Stone, R, 1987) |
| "We have described three patients whose rheumatoid arthritis was exacerbated by penicillamine." | 3.67 | Penicillamine-induced exacerbation of rheumatoid arthritis. ( Butler, D; Tiliakos, NA, 1986) |
| " D-penicillamine, a drug effective in the proliferative synovitis of rheumatoid arthritis, was evaluated in a rabbit model of hemarthroses-induced arthritis and in four hemophiliacs with chronic synovitis." | 3.67 | Treatment of hemophilic arthritis with D-penicillamine: a preliminary report. ( Corrigan, JJ; Damiano, ML; Gall, EP; Jeter, M; Kolba, KS; Meredith, K; Trombley, J, 1985) |
| "Penicillamine is now established as a useful disease remittive drug in the treatment of rheumatoid arthritis." | 3.66 | Penicillamine: an anti-rheumatoid drug. ( Jaffe, IA, 1983) |
| "Rheumatoid arthritis is a chronic inflammatory synovitis that primarily involves peripheral diarthrodial joints." | 2.37 | NIH conference. Rheumatoid arthritis: evolving concepts of pathogenesis and treatment. ( Decker, JL; Haraoui, B; Klippel, JH; Malone, DG; Schrieber, L; Steinberg, AD; Wahl, SM; Wilder, RL, 1984) |
| "Aspirin remains the cornerstone of treatment for juvenile arthritis, although tolmetin may be more effective in controlling the fever of systemic-onset disease." | 1.27 | Treatment of juvenile arthritis. ( Baum, J, 1983) |
| "Inflammation was induced in the six-day air pouch either with the non-immune irritant carrageenan or the immune irritant Bordetella pertussis." | 1.27 | The effect of anti-inflammatory and rheumatoid disease modifying drugs on prolonged immune and non-immune inflammation in the six-day air pouch of rats. ( Al-Duaij, AY; Sedgwick, AD; Willoughby, DA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (93.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Corrigan, JJ | 2 |
| Damiano, ML | 2 |
| Leissinger, C | 1 |
| Wulff, K | 1 |
| Decker, JL | 1 |
| Malone, DG | 1 |
| Haraoui, B | 1 |
| Wahl, SM | 1 |
| Schrieber, L | 1 |
| Klippel, JH | 1 |
| Steinberg, AD | 1 |
| Wilder, RL | 1 |
| Jaffe, IA | 1 |
| Alexander, GJ | 1 |
| Bacon, PA | 1 |
| Cavalcanti, F | 1 |
| Blake, DR | 1 |
| Hall, ND | 1 |
| Shekhter, AB | 1 |
| Krel', AA | 1 |
| Chichasova, NV | 1 |
| Rashchupkina, ZP | 1 |
| Baum, J | 1 |
| Bentzon, MW | 2 |
| Gad, I | 1 |
| Halberg, P | 3 |
| Halskov, O | 2 |
| Lorenzen, I | 2 |
| Al-Duaij, AY | 1 |
| Sedgwick, AD | 1 |
| Willoughby, DA | 1 |
| Olsen, N | 1 |
| Scott, DL | 1 |
| Dawes, PT | 1 |
| Collins, M | 1 |
| Stone, R | 1 |
| Joyce, DA | 1 |
| Forrest, MJ | 1 |
| Brooks, PM | 1 |
| Pugh, MC | 1 |
| Pugh, CB | 1 |
| Hørslev-Petersen, K | 1 |
| Bentsen, KD | 1 |
| Engström-Laurent, A | 1 |
| Junker, P | 1 |
| Butler, D | 1 |
| Tiliakos, NA | 1 |
| Kolba, KS | 1 |
| Gall, EP | 1 |
| Trombley, J | 1 |
| Meredith, K | 1 |
| Jeter, M | 1 |
2 reviews available for penicillamine and Synovitis
| Article | Year |
|---|---|
NIH conference. Rheumatoid arthritis: evolving concepts of pathogenesis and treatment.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Chloroquine; Gluc | 1984 |
Current concepts in clinical therapeutics: disease-modifying drugs for rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Arthritis, Rheumato | 1987 |
3 trials available for penicillamine and Synovitis
| Article | Year |
|---|---|
Treatment of chronic haemophilic synovitis in humans with D-penicillamine.
Topics: Adolescent; Adult; Antirheumatic Agents; Child; Chronic Disease; Hemarthrosis; Hemophilia A; Humans; | 2003 |
Acute phase proteins and clinical synovitis activity in patients with rheumatoid arthritis.
Topics: Acute-Phase Proteins; Arthritis, Rheumatoid; Azathioprine; Blood Sedimentation; Hemoglobinometry; Hu | 1987 |
Scintimetric assessment of synovitis activity during treatment with disease modifying antirheumatic drugs.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Azathioprine; Clinical | 1988 |
10 other studies available for penicillamine and Synovitis
| Article | Year |
|---|---|
Penicillamine: an anti-rheumatoid drug.
Topics: Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoimmune Diseases; Drug Administration Schedule; | 1983 |
Low density lymphocytes: their relationship to disease activity and to antirheumatic therapy.
Topics: Adult; Arthritis, Rheumatoid; Densitometry; Female; Gold; Humans; Lymphocyte Activation; Male; Middl | 1984 |
[Chlorbutin, azathioprine, d-penicillamine and dekaris (levamisole) in the treatment of rheumatoid arthritis patients. III. A comparative analysis of their effect on the morphological manifestations of synovitis based on puncture biopsy data].
Topics: Adult; Arthritis, Rheumatoid; Azathioprine; Biopsy, Needle; Drug Evaluation; Humans; Knee Joint; Lev | 1984 |
Treatment of juvenile arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Juvenile; Aspirin; Child; | 1983 |
The effect of anti-inflammatory and rheumatoid disease modifying drugs on prolonged immune and non-immune inflammation in the six-day air pouch of rats.
Topics: Animals; Anti-Inflammatory Agents; Bordetella pertussis; Carrageenan; Dexamethasone; Disease Models, | 1986 |
ELISA assays for IgM and IgG rheumatoid factors: their clinical correlations during therapy with slow-acting anti-rheumatic drugs.
Topics: Arthritis, Rheumatoid; Enzyme-Linked Immunosorbent Assay; Gold Sodium Thiomalate; Humans; Immunoglob | 1987 |
D-penicillamine metabolism in an in-vivo model of inflamed synovium.
Topics: Animals; Male; Penicillamine; Rats; Rats, Inbred Strains; Synovial Membrane; Synovitis; Time Factors | 1988 |
Serum amino terminal type III procollagen peptide and serum hyaluronan in rheumatoid arthritis: relation to clinical and serological parameters of inflammation during 8 and 24 months' treatment with levamisole, penicillamine, or azathioprine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Female; Humans; Hyaluronic Acid; Levamisole; Male; | 1988 |
Penicillamine-induced exacerbation of rheumatoid arthritis.
Topics: Acute Disease; Aged; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Humans; Knee Joint; Ma | 1986 |
Treatment of hemophilic arthritis with D-penicillamine: a preliminary report.
Topics: Animals; Arthritis; Hemarthrosis; Hemophilia A; Humans; Inflammation; Penicillamine; Platelet Aggreg | 1985 |