penicillamine has been researched along with Symptom Cluster in 34 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The occurrence of a neurologic syndrome that severely impaired a child's usual daily activities and his health-related quality of life after the institution of penicillamine therapy." | 7.69 | Penicillamine-related neurologic syndrome in a child affected by Wilson disease with hepatic presentation. ( Iorio, R; Pensati, P; Porzio, S; Vajro, P; Vegnente, A, 1997) |
| "A patient is described in whom the nail changes of the yellow nail syndrome developed whilst she was taking penicillamine." | 7.66 | Yellow nail syndrome associated with penicillamine therapy. ( Ilchyshyn, A; Vickers, CF, 1983) |
| "We report a chromosomally normal infant boy with congenital diffuse cutis laxa, severe micrognathia, contractures of all limbs, and central nervous system abnormalities including agenesis of the corpus callosum, born to a woman taking D-penicillamine (DP) for Wilson disease (WD) throughout her pregnancy." | 3.72 | Infant with severe penicillamine embryopathy born to a woman with Wilson disease. ( Hogge, WA; McPherson, E; Pinter, R, 2004) |
| " We tested this hypothesis in an animal model in which penicillamine causes an autoimmune syndrome in Brown Norway rats." | 3.71 | Factors that modify penicillamine-induced autoimmunity in Brown Norway rats: failure of the Th1/Th2 paradigm. ( Sayeh, E; Uetrecht, JP, 2001) |
| "The occurrence of a neurologic syndrome that severely impaired a child's usual daily activities and his health-related quality of life after the institution of penicillamine therapy." | 3.69 | Penicillamine-related neurologic syndrome in a child affected by Wilson disease with hepatic presentation. ( Iorio, R; Pensati, P; Porzio, S; Vajro, P; Vegnente, A, 1997) |
| "A patient is described in whom the nail changes of the yellow nail syndrome developed whilst she was taking penicillamine." | 3.66 | Yellow nail syndrome associated with penicillamine therapy. ( Ilchyshyn, A; Vickers, CF, 1983) |
| "Stiff skin syndrome is a sclerodermalike disorder that presents in infancy or early childhood with rock-hard skin, limited joint mobility, and mild hypertrichosis in the absence of visceral or muscle involvement, immunologic abnormalities, or vascular hyperreactivity." | 2.44 | The stiff skin syndrome: case series, differential diagnosis of the stiff skin phenotype, and review of the literature. ( Connolly, MK; Frieden, IJ; Gilliam, AE; Liu, T; McCalmont, TH; Williams, ML, 2008) |
| "The diagnosis of primary sclerosing cholangitis (PSC) is based on the characteristic cholangiographic manifestations of the condition." | 2.38 | Surgical pathology of the syndrome of primary sclerosing cholangitis. ( Ludwig, J, 1989) |
| "A 37-year-old man with Wilson's disease is described, in whom the introduction of penicillamine therapy was followed after 3." | 1.31 | Penicillamine-induced lethal status dystonicus in a patient with Wilson's disease. ( Kostić, VS; Pejović, S; Sternić, N; Svetel, M, 2001) |
| ""Autoimmune" hypoglycemia is a syndrome consisting of fasting hypoglycemia, hyperinsulinemia, and insulin-binding antibodies in a patient who has never been exposed to exogenous insulin." | 1.27 | Insulin autoimmunity as a cause of hypoglycemia. ( Benson, EA; Fredlund, PN; Ho, P; Wang, C; Wu, PC; Yueng, RT, 1984) |
| " Adverse effects occurred more frequently after rapid increases in dosage." | 1.27 | The toxicity of D-penicillamine in systemic sclerosis. ( Blair, S; Medsger, TA; Steen, VD, 1986) |
| "Fifty-eight patients with Wilson's disease are reviewed, of whom 25 symptomatic patients experienced liver disease first and 28, brain disease." | 1.26 | Clinical spectrum of Wilson's disease (hepatolenticular degeneration). ( Dobyns, WB; Goldstein, NP; Gordon, H, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (70.59) | 18.7374 |
| 1990's | 4 (11.76) | 18.2507 |
| 2000's | 6 (17.65) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, T | 1 |
| McCalmont, TH | 1 |
| Frieden, IJ | 1 |
| Williams, ML | 1 |
| Connolly, MK | 1 |
| Gilliam, AE | 1 |
| Pinter, R | 1 |
| Hogge, WA | 1 |
| McPherson, E | 1 |
| Szegedi, A | 1 |
| Surányi, P | 1 |
| Szücs, G | 1 |
| Kiss, M | 1 |
| Hunyadi, J | 1 |
| Gaál, J | 1 |
| Momoki, T | 1 |
| Terauchi, Y | 1 |
| Kaeser, HE | 1 |
| Coyle, HE | 1 |
| Chapman, RS | 1 |
| Ilchyshyn, A | 1 |
| Vickers, CF | 1 |
| Chan, HL | 1 |
| Benson, EA | 1 |
| Ho, P | 1 |
| Wang, C | 1 |
| Wu, PC | 1 |
| Fredlund, PN | 1 |
| Yueng, RT | 1 |
| Tellkamp, F | 1 |
| Kunath, B | 1 |
| Miura, M | 1 |
| Okabe, T | 1 |
| Tsubata, S | 1 |
| Takizawa, N | 1 |
| Sawaguchi, T | 1 |
| Porzio, S | 1 |
| Iorio, R | 1 |
| Vajro, P | 1 |
| Pensati, P | 1 |
| Vegnente, A | 1 |
| Svetel, M | 1 |
| Sternić, N | 1 |
| Pejović, S | 1 |
| Kostić, VS | 1 |
| Sayeh, E | 1 |
| Uetrecht, JP | 1 |
| Bierbach, H | 1 |
| Holzmann, H | 1 |
| Tan, SG | 1 |
| Rowell, NR | 1 |
| Christoph, R | 1 |
| Genth, E | 1 |
| Grussendorf, EI | 1 |
| Hartl, PW | 1 |
| Wurm, K | 1 |
| Argov, Z | 1 |
| Mastaglia, FL | 1 |
| Pierard, GE | 1 |
| Lapiere, CM | 1 |
| Lubach, D | 1 |
| Marghescu, S | 1 |
| Harkcom, TM | 1 |
| Conn, DL | 1 |
| Holley, KE | 1 |
| Dobyns, WB | 1 |
| Goldstein, NP | 1 |
| Gordon, H | 1 |
| Strickland, GT | 1 |
| Leu, ML | 1 |
| Bettendorf, U | 1 |
| Pötters, R | 1 |
| Kher, A | 1 |
| Bharucha, BA | 1 |
| Kumta, NB | 1 |
| Ichikawa, Y | 1 |
| Shimizu, H | 1 |
| Arimori, S | 1 |
| Ludwig, J | 1 |
| Weitoft, T | 1 |
| Domeij-Nyberg, B | 1 |
| Steen, VD | 1 |
| Blair, S | 1 |
| Medsger, TA | 1 |
| Shaposhnikov, OK | 1 |
| Rodionov, AN | 1 |
| Samtsov, AV | 1 |
| Kalina, P | 1 |
| Procházková, L | 1 |
| Hauftová, D | 1 |
| David, O | 1 |
| Clark, J | 1 |
| Voeller, K | 1 |
| Soyka, D | 1 |
7 reviews available for penicillamine and Symptom Cluster
| Article | Year |
|---|---|
The stiff skin syndrome: case series, differential diagnosis of the stiff skin phenotype, and review of the literature.
Topics: Age Distribution; Biopsy, Needle; Child; Child, Preschool; Disease Progression; Fascia; Female; Huma | 2008 |
[Aceruloplasminemia (hereditary ceruloplasmin deficiency) and diabetes mellitus].
Topics: Brain Diseases; Ceruloplasmin; Diabetes Mellitus; Diagnosis, Differential; Genetic Diseases, Inborn; | 2006 |
Drug-induced myasthenic syndromes.
Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Autoimmune Diseas | 1984 |
[Sarcoidosis therapy and its problems today].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Anti-Inflammatory Agents; Antineoplasti | 1978 |
Drug therapy: Disorders of neuromuscular transmission caused by drugs.
Topics: Aged; Animals; Anti-Bacterial Agents; Anticonvulsants; Cardiovascular Agents; Chloroquine; Drug-Rela | 1979 |
"Yellow nail syndrome" and rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Male; Midd | 1991 |
Surgical pathology of the syndrome of primary sclerosing cholangitis.
Topics: Biopsy; Cholangitis, Sclerosing; Gallbladder; Humans; Liver; Liver Diseases; Liver Transplantation; | 1989 |
27 other studies available for penicillamine and Symptom Cluster
| Article | Year |
|---|---|
Infant with severe penicillamine embryopathy born to a woman with Wilson disease.
Topics: Abnormalities, Drug-Induced; Agenesis of Corpus Callosum; Cutis Laxa; Female; Fetal Diseases; Fetus; | 2004 |
D-penicillamine-induced pemphigus vulgaris in a patient with scleroderma-rheumatoid arthritis overlap syndrome.
Topics: Arthritis, Rheumatoid; Female; Follow-Up Studies; Humans; Middle Aged; Pemphigus; Penicillamine; Ris | 2004 |
Eosinophilic fasciitis (Shulman syndrome) in association with morphoea and systemic sclerosis.
Topics: Eosinophils; Fascia; Humans; Inflammation; Male; Middle Aged; Penicillamine; Scleroderma, Localized; | 1980 |
Yellow nail syndrome associated with penicillamine therapy.
Topics: Adult; Female; Humans; Nail Diseases; Penicillamine; Pigmentation Disorders; Syndrome | 1983 |
Observations on drug-induced toxic epidermal necrolysis in Singapore.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antipyrine; Barbiturates; Burns; Child; Diagnosis, Differenti | 1984 |
Insulin autoimmunity as a cause of hypoglycemia.
Topics: Autoantibodies; Diagnosis, Differential; Female; Humans; Hyperplasia; Hypoglycemia; Insulin Antibodi | 1984 |
[Myasthenic syndrome--complication of D-penicillamine therapy].
Topics: Arthritis, Rheumatoid; Electromyography; Female; Humans; Middle Aged; Muscular Diseases; Penicillami | 1984 |
Chronic infantile neurological cutaneous articular syndrome in a patient from Japan.
Topics: Age of Onset; Antirheumatic Agents; Arthritis; Central Nervous System Diseases; Eye Diseases; Female | 1997 |
Penicillamine-related neurologic syndrome in a child affected by Wilson disease with hepatic presentation.
Topics: Child; Hepatolenticular Degeneration; Humans; Liver Diseases; Male; Nervous System Diseases; Penicil | 1997 |
Penicillamine-induced lethal status dystonicus in a patient with Wilson's disease.
Topics: Acute Kidney Injury; Adult; Chelating Agents; Dystonia; Fatal Outcome; Hepatolenticular Degeneration | 2001 |
Factors that modify penicillamine-induced autoimmunity in Brown Norway rats: failure of the Th1/Th2 paradigm.
Topics: Animals; Autoimmune Diseases; Autoimmunity; Drug Eruptions; Immunoglobulin E; Interferon Inducers; I | 2001 |
[Zinc deficiency syndrome].
Topics: Acrodermatitis; Anemia, Sickle Cell; Antineoplastic Agents; Humans; Malabsorption Syndromes; Parente | 1979 |
Pemphigus-like syndrome induced by D-penicillamine.
Topics: Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Middle Aged; Pemphigus; Penicillamine; Syndro | 1976 |
[Pemphigus syndrome in D-penicillamine treated rheumatoid arthritis].
Topics: Adult; Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Pemphigus; Penicillamine; Syndrome | 1978 |
Phenytoin dependent fibrosis in polyfibromatosis syndrome.
Topics: Adult; Elasticity; Fibroma; Humans; Male; Penicillamine; Phenytoin; Skin; Skin Neoplasms; Syndrome | 1979 |
[Yellow-nail syndrome from d-penicillamine].
Topics: Adult; Female; Humans; Lymphedema; Nail Diseases; Penicillamine; Pigmentation Disorders; Sclerosis; | 1979 |
D-penicillamine and lupus erythematosuslike syndrome.
Topics: Adult; Arthritis, Rheumatoid; Female; Humans; Lupus Erythematosus, Systemic; Penicillamine; Syndrome | 1978 |
Clinical spectrum of Wilson's disease (hepatolenticular degeneration).
Topics: Adolescent; Adult; Brain Diseases; Child; Copper; Cornea; Dimercaprol; Female; Hepatolenticular Dege | 1979 |
Wilson's disease. Clinical and laboratory maniestations in 40 patients.
Topics: Adolescent; Adult; Blood Cell Count; Blood Platelets; Ceruloplasmin; Child; Copper; Cornea; Female; | 1975 |
[Moschcowitz's syndrome following D-penicillamine medication].
Topics: Aged; Anemia, Hemolytic; Arthritis, Rheumatoid; Female; Humans; Intracranial Embolism and Thrombosis | 1975 |
Wilson's disease: initial worsening of neurologic syndrome with penicillamine therapy.
Topics: Child; Female; Hepatolenticular Degeneration; Humans; Nervous System Diseases; Penicillamine; Syndro | 1992 |
[A fatal drug-induced autoimmune syndrome].
Topics: Aged; Autoimmune Diseases; Brain; Humans; Lung; Male; Penicillamine; Radiography; Shock; Syndrome; T | 1989 |
The toxicity of D-penicillamine in systemic sclerosis.
Topics: Arthritis, Rheumatoid; Digestive System Diseases; Dose-Response Relationship, Drug; Drug Eruptions; | 1986 |
[Schulman's eosinophilic fasciitis: update on diagnosis and treatment].
Topics: Eosinophilia; Fasciitis; Female; Humans; Middle Aged; Penicillamine; Syndrome | 1986 |
[A syndrome similar to systemic lupus erythematosus caused by penicillamine in patients with Wilson's disease].
Topics: Adult; Hepatolenticular Degeneration; Humans; Lupus Erythematosus, Systemic; Male; Penicillamine; Sy | 1985 |
Lead and hyperactivity.
Topics: Central Nervous System; Chelating Agents; Child, Preschool; Female; Humans; Hyperkinesis; Infant; Le | 1972 |
[Syndrome involving the extrapyramidal motor systems and their drug treatment].
Topics: Amantadine; Antiparkinson Agents; Basal Ganglia Diseases; Dihydroxyphenylalanine; gamma-Aminobutyric | 1974 |