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penicillamine and Skin Diseases

penicillamine has been researched along with Skin Diseases in 76 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Skin Diseases: Diseases involving the DERMIS or EPIDERMIS.

Research Excerpts

ExcerptRelevanceReference
"A patient with Wilson's disease who developed elastosis perforans serpiginosa and localized cutis laxa during prolonged treatment with D-penicillamine is described."7.69D-penicillamine-induced elastosis perforans serpiginosa and localized cutis laxa in a patient with Wilson's disease. ( Amichai, B; Metzker, A; Rotem, A, 1994)
"A large air cyst was removed from the right lung of a 29-year-old female patient with Wilson's disease and penicillamine-induced perforating elastosis, the cyst first appearing after 9 years of treatment with penicillamine."7.66[Penicillamine-induced elastosis perforans serpiginosa and pulmonary cyst in Wilson's disease (author's transl)]. ( Bardach, G; Bardach, H; Gebhart, W; Niebauer, G, 1981)
"Adverse effects to D-penicillamine were studied prospectively over 3 years in 259 patients with rheumatoid arthritis."7.66Adverse effects of D-penicillamine in rheumatoid arthritis. ( Atkins, CJ; Offer, RC; Patterson, AC; Robinson, HS; Stein, HB; Teufel, A, 1980)
"A 2 1/4 year-old boy was treated for cystinuria and urolithiasis with high fluid intake, sodium bicarbonate, and D-penicillamine, over a period of 5 3/4 years, unauthorized interruptions and prescribed pauses included."7.66Skin and bone lesions (dermato-osteolathyrism), possible side effects of D-penicillamine treatment, in a boy with cystinuria. ( Gitzelmann, R; Otten, A; Steinmann, B, 1979)
"We describe a 14-year-old boy with Wilson disease (WD) who first developed pseudo-pseudoxanthoma elasticum (PPXE) after 4."5.56Pediatric Pseudo-pseudoxanthoma Elasticum Resulting From D-Penicillamine Treatment for Wilson Disease. ( Corey, K; Hawryluk, EB; Schmidt, B; Sheu Song, J; Yu, Z, 2020)
"A retrospective study of penicillamine toxicity in 156 patients yielded a high incidence of toxic reaction (62%), necessitating discontinuation of the drug therapy in 36% of the patients."5.26Toxicity of penicillamine. A serious limitation to therapy in rheumatoid arthritis. ( Bernhard, GC; Goldman, AL; Halverson, PB; Kozin, F, 1978)
"Elastosis perforans serpiginosa (EPS) and the elastotic changes of pseudoxanthoma elasticum (PXE) are rare but well-recognized side-effects of long-term penicillamine therapy."3.69Penicillamine-induced elastosis perforans serpiginosa treated successfully with isotretinoin. ( Norris, PG; Ratnavel, RC, 1994)
"A patient with Wilson's disease who developed elastosis perforans serpiginosa and localized cutis laxa during prolonged treatment with D-penicillamine is described."3.69D-penicillamine-induced elastosis perforans serpiginosa and localized cutis laxa in a patient with Wilson's disease. ( Amichai, B; Metzker, A; Rotem, A, 1994)
"The incidence of adverse reactions to D-penicillamine in 155 patients with rheumatoid arthritis was analysed and compared with their history of adverse reactions to gold."3.66Adverse reactions to D-penicillamine after gold toxicity. ( Dodd, MJ; Griffiths, ID; Thompson, M, 1980)
"A large air cyst was removed from the right lung of a 29-year-old female patient with Wilson's disease and penicillamine-induced perforating elastosis, the cyst first appearing after 9 years of treatment with penicillamine."3.66[Penicillamine-induced elastosis perforans serpiginosa and pulmonary cyst in Wilson's disease (author's transl)]. ( Bardach, G; Bardach, H; Gebhart, W; Niebauer, G, 1981)
"Adverse effects to D-penicillamine were studied prospectively over 3 years in 259 patients with rheumatoid arthritis."3.66Adverse effects of D-penicillamine in rheumatoid arthritis. ( Atkins, CJ; Offer, RC; Patterson, AC; Robinson, HS; Stein, HB; Teufel, A, 1980)
"A 2 1/4 year-old boy was treated for cystinuria and urolithiasis with high fluid intake, sodium bicarbonate, and D-penicillamine, over a period of 5 3/4 years, unauthorized interruptions and prescribed pauses included."3.66Skin and bone lesions (dermato-osteolathyrism), possible side effects of D-penicillamine treatment, in a boy with cystinuria. ( Gitzelmann, R; Otten, A; Steinmann, B, 1979)
"Penicillamine-induced cutaneous elastosis perforans serpiginosa associated with a large air-cyst in the right lung is described in a 29-year-old female patient with Wilson disease."3.66"Lumpy-bumpy" elastic fibers in the skin and lungs of a patient with a penicillamine-induced elastosis perforans serpiginosa. ( Bardach, H; Gebhart, W; Niebauer, G, 1979)
" The successful therapeutic uses of penicillamine have been hindered by its numerous adverse effects, both cutaneous and extra-cutaneous."2.49Penicillamine revisited: historic overview and review of the clinical uses and cutaneous adverse effects. ( Abbas, O; Ishak, R, 2013)
"The use of D-penicillamine in systemic sclerosis (SSc) has been controversial."2.41D-penicillamine in systemic sclerosis? Yes! ( Baker, C; Lucas, M; Medsger, TA; Wildy, KS, 2001)
"We describe a 14-year-old boy with Wilson disease (WD) who first developed pseudo-pseudoxanthoma elasticum (PPXE) after 4."1.56Pediatric Pseudo-pseudoxanthoma Elasticum Resulting From D-Penicillamine Treatment for Wilson Disease. ( Corey, K; Hawryluk, EB; Schmidt, B; Sheu Song, J; Yu, Z, 2020)
" Over a 2-yr period we have prospectively reviewed 114 patients with a suspected adverse cutaneous reaction to anti-rheumatic drugs."1.29Suspected cutaneous drug toxicity in rheumatoid arthritis--an evaluation. ( Davis, MJ; Dawes, PT; Mattey, DL; Smith, AG; Wilkinson, SM, 1993)
"We describe a patient with Wilson's disease who developed extensive penicillamine dermatopathy."1.28Penicillamine dermatopathy with lymphangiectases. A clinical, immunohistologic, and ultrastructural study. ( Goldstein, JB; Hambrick, GW; Hsu, A; McNutt, NS, 1989)
"In other situations, as in the treatment of keloids, physicians may wish to introduce drugs known to reduce scar formation into the biologic environment in which wound healing ensues."1.26Wound healing: a review. IV. Systemic medications affecting wound healing. ( Pollack, SV, 1982)
"A sibling had died in childhood with Wilson's disease."1.26Porphyria cutanea tarda complicating Wilson's disease. ( Chesney, TM; Chow, JF; Kaplan, RJ; Wardlaw, LL, 1981)
"A retrospective study of penicillamine toxicity in 156 patients yielded a high incidence of toxic reaction (62%), necessitating discontinuation of the drug therapy in 36% of the patients."1.26Toxicity of penicillamine. A serious limitation to therapy in rheumatoid arthritis. ( Bernhard, GC; Goldman, AL; Halverson, PB; Kozin, F, 1978)
"A patient with Wilson disease, under prolonged treatment with penicillamine, developed lesions of elastosis perforans serpiginosa (EPS)."1.26Elastosis perforans serpiginosa induced by penicillamine. ( Hukill, PB; Kirsch, N, 1977)

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-199047 (61.84)18.7374
1990's8 (10.53)18.2507
2000's2 (2.63)29.6817
2010's15 (19.74)24.3611
2020's4 (5.26)2.80

Authors

AuthorsStudies
Atzori, L2
Ferreli, C1
Agosta, D1
Mou, M1
Coni, P1
Lachowicz, JI1
Pilloni, L1
Valenzuela-Ubiña, S1
Jiménez-Gallo, D1
Russo-de la Torre, F1
Linares-Barrios, M1
Yu, Z1
Sheu Song, J1
Schmidt, B1
Corey, K1
Hawryluk, EB1
Bahrani, B1
Zabihi-Pour, D1
Kamil, ZS1
Rosen, CF1
Thwaites, PA1
Khan, SA1
Asadi, K1
Angus, PW1
Ashida, M1
Okubo, Y1
Iwanaga, A1
Utani, A1
Yao, XY1
Wen, GD1
Zhou, C1
Liu, BY1
Du, J1
Chen, Z1
Zhang, JZ1
Montesu, MA1
Onnis, G1
Gunnella, S1
Lissia, A1
Satta, R1
Ishak, R1
Abbas, O1
Neri, I2
Gurioli, C1
Raggi, MA2
Saracino, MA2
Morganti, E2
Bugamelli, F2
de Ponti, F1
Vaccari, S1
Patrizi, A2
Balestri, R2
Hellriegel, S1
Bertsch, HP1
Emmert, S1
Schön, MP1
Haenssle, HA1
Ranucci, G1
Di Dato, F1
Leone, F1
Vajro, P1
Spagnuolo, MI1
Iorio, R1
Chabra, IS1
Grandinetti, LM1
Wang, D1
Liang, J1
Xu, J1
Chen, L1
Bennett, JA1
Clarke, JT1
Ioffreda, MD1
Menzies, S1
Kirby, B1
Ramírez-Bellver, JL1
Bernárdez, C1
Macías, E1
Moya, L1
Molina-Ruiz, AM1
Cannata Ortiz, P1
Requena, L1
Pinna, AL1
Pau, M1
Aste, N1
Cannistraci, C1
Touraine, R1
Revuz, J1
Dubertret, L1
de Prost, Y1
Guillaume, JC1
Venencie, PY1
Morel, P1
Summerfield, GP1
Bellingham, AJ1
Bunch, C1
Woodrow, JC1
Hodson, ME1
Haslam, PL1
Spiro, SG1
Turner-Warwick, M1
Dodd, MJ1
Griffiths, ID1
Thompson, M1
Gloor, M1
Bersch, A1
Rosenblum, GA1
Runge, LA1
Pollack, SV1
Reymond, JL1
Stoebner, P1
Zambelli, P1
Beani, JC1
Amblard, P1
Chesney, TM1
Wardlaw, LL1
Kaplan, RJ1
Chow, JF1
Bardach, H4
Gebhart, W3
Niebauer, G2
Bardach, G1
Stein, HB1
Patterson, AC1
Offer, RC1
Atkins, CJ1
Teufel, A1
Robinson, HS1
Ratnavel, RC1
Norris, PG1
Amichai, B1
Rotem, A1
Metzker, A1
Wilkinson, SM1
Smith, AG1
Davis, MJ1
Mattey, DL1
Dawes, PT1
Miura, M1
Okabe, T1
Tsubata, S1
Takizawa, N1
Sawaguchi, T1
Marie, I1
Lévesque, H1
Courtois, H1
Hill, VA1
Seymour, CA1
Mortimer, PS1
Medsger, TA1
Lucas, M1
Wildy, KS1
Baker, C1
Schulze, P1
Moynahan, EJ1
Steinmann, B1
Otten, A1
Gitzelmann, R1
Hill, HF2
Dahl, MV1
Halverson, PB1
Kozin, F1
Bernhard, GC1
Goldman, AL1
Davis, P1
Bleehen, SS1
Kirsch, N1
Hukill, PB1
Jean-Baptiste, G1
Uitto, J1
Jimenez, S1
Ruocco, V1
Pisani, M1
de Angelis, E1
Lombardi, ML1
Goldstein, JB1
McNutt, NS1
Hambrick, GW1
Hsu, A1
Roth, DE1
Spencer, LV1
Ahrens, EM1
Yokel, BK1
Hood, AF1
Anhalt, GJ1
Woo, TY1
Rasmussen, JE1
Camus, JP1
Koeger, AC1
Dootson, G1
Sarkany, I2
Graham-Brown, RA1
Price, RG1
Prentice, RS1
Cashin, CH1
Lewis, EJ1
Burden, T1
Wassef, M1
Galian, A1
Pepin, B1
Haguenau, M1
Vassel, P1
Hautefeuille, P1
Brazy, J1
Mjolnerod, OK1
Dommerud, SA1
Rasmussen, K1
Gjeruldsen, ST1
Huskisson, EC2
Gibson, TJ2
Balme, HW2
Berry, H2
Burry, HC2
Grahame, R3
Hart, FD2
Henderson, DR2
Wojtulewski, JA2
Civatte, J1
Belaich, S1
Blanchet, P1
Charlebois, G1
Cadotte, M1
Barbeau, A1
Pass, F1
Goldfischer, S1
Sternlieb, I1
Scheinberg, IH1
Witzgall, H1
Bluestone, R1
Holloway, V1
Holt, PJ1
Grupper, C1
Durepaire, R1
Golding, JR1
Wilson, JV1
Day, AT1
Guilaine, MJ1
Grener, AC1

Reviews

11 reviews available for penicillamine and Skin Diseases

ArticleYear
Elastosis perforans serpiginosa: causes and associated disorders.
    European journal of dermatology : EJD, 2018, Aug-01, Volume: 28, Issue:4

    Topics: Adult; Animals; Chelating Agents; Female; Hepatolenticular Degeneration; Humans; Penicillamine; Skin

2018
Penicillamine revisited: historic overview and review of the clinical uses and cutaneous adverse effects.
    American journal of clinical dermatology, 2013, Volume: 14, Issue:3

    Topics: Chelating Agents; Humans; Penicillamine; Skin Diseases

2013
D-penicillamine elastosis perforans serpiginosa: description of two cases and review of the literature.
    Dermatology online journal, 2011, Apr-15, Volume: 17, Issue:4

    Topics: Adult; Chelating Agents; Cryotherapy; Hepatolenticular Degeneration; Humans; Male; Penicillamine; Sk

2011
D-penicillamine in systemic sclerosis? Yes!
    Scandinavian journal of rheumatology, 2001, Volume: 30, Issue:4

    Topics: Antirheumatic Agents; Collagen; Dose-Response Relationship, Drug; Double-Blind Method; Fibrosis; Hum

2001
[Indications and limits of long-term therapy with immunosuppressive (and cytostatic) agents in various chronic skin diseases].
    Zeitschrift fur arztliche Fortbildung, 1977, Jun-15, Volume: 71, Issue:12

    Topics: Arthritis, Reactive; Azathioprine; Chronic Disease; Cyclophosphamide; Dermatomyositis; Humans; Immun

1977
Penicillamine and disorders affecting dermal collagen.
    Proceedings of the Royal Society of Medicine, 1977, Volume: 70 Suppl 3

    Topics: Collagen; Humans; Penicillamine; Skin; Skin Diseases

1977
D-penicillamine in the treatment of rheumatoid arthritis and progressive systemic sclerosis.
    The British journal of dermatology, 1976, Volume: 94, Issue:6

    Topics: Animals; Arthritis, Rheumatoid; Chelating Agents; Collagen; Copper; Humans; Leukopenia; Nephrotic Sy

1976
Fibrotic skin diseases. Clinical presentations, etiologic considerations, and treatment options.
    Archives of dermatology, 1990, Volume: 126, Issue:5

    Topics: Collagen; Fibrosis; Gene Expression; Humans; Penicillamine; Skin Diseases

1990
Cutaneous reactions to drugs used for rheumatologic disorders.
    The Medical clinics of North America, 1989, Volume: 73, Issue:5

    Topics: Acetates; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Antimetabolites; Cyclosp

1989
[D-penicillamine and collagen].
    Annales de biologie clinique, 1986, Volume: 44, Issue:3

    Topics: Aminopropionitrile; Arthritis, Rheumatoid; Autoantibodies; Bronchi; Cicatrix; Collagen; Collagen Dis

1986
[Dermatology from 1969 to 1973].
    La Revue du praticien, 1974, Apr-21, Volume: 24, Issue:23

    Topics: Agammaglobulinemia; Blood Protein Disorders; Bromides; Candidiasis, Cutaneous; Carcinoid Tumor; Derm

1974

Trials

3 trials available for penicillamine and Skin Diseases

ArticleYear
Treatment of rheumatoid arthritis with penicillamine.
    Seminars in arthritis and rheumatism, 1977, Volume: 6, Issue:4

    Topics: Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Dru

1977
Trial comparing D-penicillamine and gold in rheumatoid arthritis. Preliminary report.
    Annals of the rheumatic diseases, 1974, Volume: 33, Issue:6

    Topics: Agglutination Tests; Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Feeding a

1974
Proceedings: Penicillamine or gold for rheumatoid arthritis? Multicentre trial using 'blind' observers. The first six months.
    Annals of the rheumatic diseases, 1974, Volume: 33, Issue:4

    Topics: Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as Topic; Female; Gold; Humans; Male; Pa

1974

Other Studies

62 other studies available for penicillamine and Skin Diseases

ArticleYear
Generalized scleroderma-like induration associated with D-penicillamine elastosis perforans serpiginosa in Wilson's disease.
    International journal of dermatology, 2023, Volume: 62, Issue:2

    Topics: Hepatolenticular Degeneration; Humans; Penicillamine; Scleroderma, Localized; Scleroderma, Systemic;

2023
Elastosis perforans serpiginosa induced by d-penicillamine treated with cyclosporine and allopurinol.
    Dermatologic therapy, 2020, Volume: 33, Issue:4

    Topics: Allopurinol; Child; Cyclosporine; Humans; Penicillamine; Skin Diseases

2020
Pediatric Pseudo-pseudoxanthoma Elasticum Resulting From D-Penicillamine Treatment for Wilson Disease.
    Journal of pediatric gastroenterology and nutrition, 2020, Volume: 71, Issue:6

    Topics: Adolescent; Adult; Hepatolenticular Degeneration; Humans; Male; Penicillamine; Pseudoxanthoma Elasti

2020
A case of elastosis perforans serpiginosa associated with long-term treatment with penicillamine.
    International journal of dermatology, 2020, Volume: 59, Issue:11

    Topics: Elastic Tissue; Humans; Long-Term Care; Penicillamine; Skin Diseases

2020
Elastosis perforans serpiginosa in a patient with Wilson's disease.
    The lancet. Gastroenterology & hepatology, 2017, Volume: 2, Issue:2

    Topics: Adult; Chelating Agents; Hepatolenticular Degeneration; Humans; Male; Penicillamine; Skin Diseases

2017
No rubbing, no elastosis perforans serpiginosa.
    The Journal of dermatology, 2017, Volume: 44, Issue:8

    Topics: Chelating Agents; Diagnosis, Differential; Female; Hepatolenticular Degeneration; Humans; Middle Age

2017
D-penicillamine-induced Elastosis Perforans Serpiginosa.
    Chinese medical journal, 2017, Aug-20, Volume: 130, Issue:16

    Topics: Humans; Isotretinoin; Male; Nicotinic Acids; Penicillamine; Skin Diseases; Triamcinolone Acetonide

2017
Detection of D-penicillamine in skin lesions in a case of dermal elastosis after a previous long-term treatment for Wilson's disease.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2015, Volume: 29, Issue:2

    Topics: Chelating Agents; Female; Hepatolenticular Degeneration; Humans; Middle Aged; Penicillamine; Skin Di

2015
Elastosis perforans serpiginosa: a case of a penicillamine-induced degenerative dermatosis.
    JAMA dermatology, 2014, Volume: 150, Issue:7

    Topics: Aged; Chelating Agents; Cutis Laxa; Hepatolenticular Degeneration; Humans; Male; Middle Aged; Penici

2014
Penicillamine-induced Elastosis Perforans Serpiginosa in Wilson Disease: Is Useful Switching to Zinc?
    Journal of pediatric gastroenterology and nutrition, 2017, Volume: 64, Issue:3

    Topics: Adolescent; Chelating Agents; Hepatolenticular Degeneration; Humans; Male; Penicillamine; Skin; Skin

2017
Asymptomatic annular plaques on the neck.
    Cutis, 2014, Volume: 94, Issue:4

    Topics: Adult; Antirheumatic Agents; Biopsy; Drug-Related Side Effects and Adverse Reactions; Female; Humans

2014
Effective treatment of d-penicillamine induced elastosis perforans serpiginosa with ALA-PDT.
    Photodiagnosis and photodynamic therapy, 2015, Volume: 12, Issue:1

    Topics: Adult; Aminolevulinic Acid; Chelating Agents; Humans; Male; Penicillamine; Photochemotherapy; Photos

2015
Annular keratotic papules on the extremities.
    Journal of the American Academy of Dermatology, 2015, Volume: 73, Issue:5

    Topics: Adult; Antirheumatic Agents; Elastic Tissue; Extremities; Female; Humans; Penicillamine; Scleroderma

2015
Drug-induced elastosis perforans serpiginosa.
    BMJ case reports, 2015, Dec-07, Volume: 2015

    Topics: Adult; Biopsy; Chelating Agents; Female; Humans; Penicillamine; Skin Diseases

2015
Dermoscopy and direct immunofluorescence findings of elastosis perforans serpiginosa.
    Clinical and experimental dermatology, 2016, Volume: 41, Issue:6

    Topics: Adult; Chelating Agents; Dermoscopy; Elastic Tissue; Female; Fluorescent Antibody Technique, Direct;

2016
A novel HPLC-electrochemical detection approach for the determination of D-penicillamine in skin specimens.
    Talanta, 2013, Jan-15, Volume: 103

    Topics: Case-Control Studies; Chromatography, High Pressure Liquid; Disulfides; Electrochemistry; Electrodes

2013
[Present status of dermatology].
    La Revue du praticien, 1980, Nov-21, Volume: 30, Issue:53

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Eruptions; Female; Humans; Leg Ulcer; Lit

1980
[Skin manifestations observed during treatment with penicillamine and its derivatives].
    Annales de medecine interne, 1984, Volume: 135, Issue:8

    Topics: Drug Eruptions; Elastic Tissue; Humans; Pemphigus; Penicillamine; Penicillins; Pyrithioxin; Skin Dis

1984
Successful treatment of chronic cutaneous graft-versus-host-disease (GVHD) with penicillamine.
    Clinical and laboratory haematology, 1983, Volume: 5, Issue:3

    Topics: Adult; Anemia, Aplastic; Bone Marrow Transplantation; Chronic Disease; Cyclophosphamide; Facial Expr

1983
Digital vasculitis in patients with cryptogenic fibrosing alveolitis.
    British journal of diseases of the chest, 1984, Volume: 78, Issue:2

    Topics: Adult; Aged; Female; Fingers; Humans; Immunosuppressive Agents; Male; Middle Aged; Penicillamine; Pr

1984
Adverse reactions to D-penicillamine after gold toxicity.
    British medical journal, 1980, Jun-21, Volume: 280, Issue:6230

    Topics: Arthritis, Rheumatoid; Gold Sodium Thiomalate; Humans; Penicillamine; Proteinuria; Skin Diseases

1980
[Elastoma intrapapillare perforans verruciforme (Lutz-Miescher) following long-term therapy with D-penicillamine].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1982, Volume: 33, Issue:5

    Topics: Adult; Cystinuria; Humans; Long-Term Care; Male; Penicillamine; Skin Diseases

1982
Liquid nitrogen cryotherapy in a case of elastosis perforans serpiginosa.
    Journal of the American Academy of Dermatology, 1983, Volume: 8, Issue:5

    Topics: Adult; Cryosurgery; Humans; Male; Nitrogen; Penicillamine; Skin Diseases

1983
Risk/benefit analysis of hydroxychloroquine sulfate treatment in rheumatoid arthritis.
    The American journal of medicine, 1983, Jul-18, Volume: 75, Issue:1A

    Topics: Actuarial Analysis; Arthritis, Rheumatoid; Gastrointestinal Diseases; Gold; Humans; Hydroxychloroqui

1983
Wound healing: a review. IV. Systemic medications affecting wound healing.
    The Journal of dermatologic surgery and oncology, 1982, Volume: 8, Issue:8

    Topics: Adrenal Cortex Hormones; Aminopropionitrile; Animals; Anti-Inflammatory Agents; Anticoagulants; Anti

1982
Penicillamine induced elastosis perforans serpiginosa: an ultrastructural study of two cases.
    Journal of cutaneous pathology, 1982, Volume: 9, Issue:5

    Topics: Adolescent; Elastic Tissue; Female; Granuloma; Humans; Male; Penicillamine; Skin Diseases

1982
Porphyria cutanea tarda complicating Wilson's disease.
    Journal of the American Academy of Dermatology, 1981, Volume: 4, Issue:1

    Topics: Adult; Female; Hepatolenticular Degeneration; Humans; Penicillamine; Porphyrias; Skin Diseases

1981
[Penicillamine-induced dermolytic dermatosis in a patient with Wilson's disease (author's transl)].
    Dermatologica, 1981, Volume: 162, Issue:6

    Topics: Adult; Connective Tissue Diseases; Female; Hepatolenticular Degeneration; Humans; Penicillamine; Ski

1981
[Penicillamine-induced elastosis perforans serpiginosa and pulmonary cyst in Wilson's disease (author's transl)].
    Wiener klinische Wochenschrift, 1981, Feb-20, Volume: 93, Issue:4

    Topics: Adult; Cysts; Elastic Tissue; Female; Hepatolenticular Degeneration; Humans; Lung; Lung Diseases; Pe

1981
Adverse effects of D-penicillamine in rheumatoid arthritis.
    Annals of internal medicine, 1980, Volume: 92, Issue:1

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Drug Administration Schedule; Gastrointestinal Disea

1980
Penicillamine-induced elastosis perforans serpiginosa treated successfully with isotretinoin.
    Dermatology (Basel, Switzerland), 1994, Volume: 189, Issue:1

    Topics: Adult; Elastic Tissue; Female; Hepatolenticular Degeneration; Humans; Isotretinoin; Penicillamine; P

1994
D-penicillamine-induced elastosis perforans serpiginosa and localized cutis laxa in a patient with Wilson's disease.
    Israel journal of medical sciences, 1994, Volume: 30, Issue:8

    Topics: Child; Connective Tissue Diseases; Cutis Laxa; Elastic Tissue; Female; Hepatolenticular Degeneration

1994
Suspected cutaneous drug toxicity in rheumatoid arthritis--an evaluation.
    British journal of rheumatology, 1993, Volume: 32, Issue:9

    Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis,

1993
Chronic infantile neurological cutaneous articular syndrome in a patient from Japan.
    European journal of pediatrics, 1997, Volume: 156, Issue:8

    Topics: Age of Onset; Antirheumatic Agents; Arthritis; Central Nervous System Diseases; Eye Diseases; Female

1997
[D-penicillamine: an outdated cure for systemic scleroderma?].
    La Revue de medecine interne, 1999, Volume: 20, Issue:12

    Topics: Antirheumatic Agents; Humans; Penicillamine; Prognosis; Scleroderma, Systemic; Skin Diseases; Surviv

1999
Pencillamine-induced elastosis perforans serpiginosa and cutis laxa in Wilson's disease.
    The British journal of dermatology, 2000, Volume: 142, Issue:3

    Topics: Adult; Chelating Agents; Cutis Laxa; Elastic Tissue; Hepatolenticular Degeneration; Humans; Male; Pe

2000
Skin and bone lesions (dermato-osteolathyrism), possible side effects of D-penicillamine treatment, in a boy with cystinuria.
    Helvetica paediatrica acta, 1979, Volume: 34, Issue:3

    Topics: Atrophy; Bicarbonates; Bone and Bones; Bone Diseases; Child, Preschool; Cystinuria; Drug Eruptions;

1979
"Lumpy-bumpy" elastic fibers in the skin and lungs of a patient with a penicillamine-induced elastosis perforans serpiginosa.
    Journal of cutaneous pathology, 1979, Volume: 6, Issue:4

    Topics: Adult; Cysts; Elastic Tissue; Female; Humans; Lung; Lung Diseases; Microscopy, Electron; Penicillami

1979
[Penicillamine-induced elastosis perforans serpiginosa (proceedings)].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1979, Volume: 30, Issue:8

    Topics: Adult; Elastic Tissue; Female; Humans; Penicillamine; Skin Diseases

1979
Chemotaxis: death march of the phagocyte.
    Archives of dermatology, 1979, Volume: 115, Issue:12

    Topics: Chemotactic Factors; Chemotaxis, Leukocyte; Clindamycin; Humans; Ibuprofen; Levamisole; Penicillamin

1979
Toxicity of penicillamine. A serious limitation to therapy in rheumatoid arthritis.
    JAMA, 1978, Oct-20, Volume: 240, Issue:17

    Topics: Adult; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Female; Gastrointestinal Diseases; H

1978
Elastosis perforans serpiginosa induced by penicillamine.
    Archives of dermatology, 1977, Volume: 113, Issue:5

    Topics: Adult; Elastic Tissue; Hepatolenticular Degeneration; Humans; Male; Penicillamine; Skin; Skin Diseas

1977
[Rheumatoid arthritis. Diagnosis, anatomopathology, evolution, prognosis, treatment].
    La Revue du praticien, 1991, Sep-01, Volume: 41, Issue:19

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antirheumatic Agent

1991
Biochemical acantholysis provoked by thiol drugs.
    Archives of dermatology, 1990, Volume: 126, Issue:7

    Topics: Acantholysis; Captopril; Humans; Pemphigus; Penicillamine; Skin Diseases; Sulfhydryl Compounds; Tiop

1990
Penicillamine dermatopathy with lymphangiectases. A clinical, immunohistologic, and ultrastructural study.
    Archives of dermatology, 1989, Volume: 125, Issue:1

    Topics: Adult; Biopsy; Collagen; Connective Tissue; Elastin; Hepatolenticular Degeneration; Humans; Immunoen

1989
Induction of acantholysis in organ explant culture by penicillamine and captopril.
    Archives of dermatology, 1989, Volume: 125, Issue:10

    Topics: Acantholysis; Adult; Captopril; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Organ Cul

1989
Disorders of transepidermal elimination. Part 1.
    International journal of dermatology, 1985, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Cartilage Diseases; Child; Child, Preschool; Collagen Diseases; Down Syndro

1985
D-penicillamine induced dermopathy in Wilson's disease.
    Clinical and experimental dermatology, 1987, Volume: 12, Issue:1

    Topics: Adult; Female; Hepatolenticular Degeneration; Humans; Penicillamine; Skin Diseases

1987
Lichen sclerosus et atrophicus. With primary biliary cirrhosis and lichen planus.
    International journal of dermatology, 1986, Volume: 25, Issue:5

    Topics: Autoantibodies; Humans; Lichen Planus; Liver Cirrhosis, Biliary; Male; Middle Aged; Mitochondria; Pe

1986
Penicillamine-induced elastosis perforans serpiginosa. Tip of the iceberg?
    The American Journal of dermatopathology, 1986, Volume: 8, Issue:4

    Topics: Adult; Elastic Tissue; Female; Humans; Penicillamine; Skin Diseases

1986
The development of screening tests for D-penicillamine-like antirheumatic activity based on in vivo interactions with copper.
    British journal of rheumatology, 1985, Volume: 24, Issue:2

    Topics: Animals; Arthritis, Rheumatoid; Capillary Permeability; Copper; Drug Interactions; Extremities; Fema

1985
Unusual digestive lesions in a patient with Wilson's disease treated with long-term penicillamine.
    The New England journal of medicine, 1985, Jul-04, Volume: 313, Issue:1

    Topics: Hepatolenticular Degeneration; Humans; Ileal Diseases; Male; Middle Aged; Penicillamine; Sarcoma, Ka

1985
Congenital connective-tissue defect probably due to D-penicillamine treatment in pregnancy.
    Lancet (London, England), 1971, Apr-03, Volume: 1, Issue:7701

    Topics: Collagen Diseases; Connective Tissue; Cystinuria; Elasticity; Female; Humans; Infant, Newborn; Infan

1971
Selection of patients with rheumatoid arthritis to be treated with penicillamine, and their management.
    Current medical research and opinion, 1974, Volume: 2, Issue:9

    Topics: Administration, Oral; Arthritis, Rheumatoid; Blood Platelet Disorders; Feeding and Eating Disorders;

1974
[Cutis hyperelastica following prolonged administration of penicillamine in a patient with Wilson's disease].
    L'union medicale du Canada, 1972, Volume: 101, Issue:5

    Topics: Adolescent; Biopsy; Copper; Ehlers-Danlos Syndrome; Female; Hepatolenticular Degeneration; Humans; P

1972
Elastosis perforans serpiginosa during penicillamine therapy for Wilson disease.
    Archives of dermatology, 1973, Volume: 108, Issue:5

    Topics: Adult; Biopsy; Hepatolenticular Degeneration; Humans; Male; Penicillamine; Skin Diseases

1973
[Gold therapy in chronic joint rheumatism].
    Der Internist, 1967, Volume: 8, Issue:7

    Topics: Acute Kidney Injury; Arthritis, Rheumatoid; Dimercaprol; Drug Hypersensitivity; Gold; Hematologic Di

1967
Treatment of systemic sclerosis with D-penicillamine. A new method of observing the effects of treatment.
    Annals of the rheumatic diseases, 1970, Volume: 29, Issue:2

    Topics: Adult; Aged; Elasticity; Female; Humans; Male; Middle Aged; Penicillamine; Proteinuria; Scleroderma,

1970
[Dyschromic and keratosic chronic arsenicism].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1970, Volume: 77, Issue:1

    Topics: Adult; Arsenic; Arsenicals; Bronchitis; Female; Humans; Keratosis; Penicillamine; Pigmentation Disor

1970
Observations on the treatment of rheumatoid disease with penicillamine.
    Postgraduate medical journal, 1970, Volume: 46, Issue:540

    Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Female; Gastrointestinal Diseases; Humans;

1970
[Gougerot's trisymptom type of vascular purpura in connection with a mixed cryoglobulinemia. Suspensive action of D-penicillamine].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1970, Volume: 77, Issue:6

    Topics: Adult; Cryoglobulins; Erythema; Female; Humans; Penicillamine; Purpura; Skin Diseases

1970
Schizophrenia melanosis. Iatrogenic--congenital defect?
    Diseases of the nervous system, 1968, Volume: 29, Issue:3

    Topics: Animals; Anura; Copper; Diet; Female; Humans; Male; Melanins; Melanosis; Melatonin; Models, Biologic

1968