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penicillamine and Sjogren's Syndrome

penicillamine has been researched along with Sjogren's Syndrome in 21 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Sjogren's Syndrome: Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.

Research Excerpts

ExcerptRelevanceReference
" Conditions often associated with rheumatoid arthritis and also thought to have an immunologic basis, such as Sjögren's syndrome, Felty's syndrome, and rheumatoid vasculitis, and reactions to medications, such as gold and penicillamine, reveal an interesting spectrum of immunogenetic relationships."4.76Rheumatoid arthritis: relationship with HLA-D. ( Stastny, P, 1983)
"Characteristics of patients on penicillamine therapy for rheumatoid arthritis were correlated with the occurrence of different side-effects."3.66Factors affecting the development of penicillamine side-effects. ( Corke, CF; Huskisson, EC, 1978)
"Primary biliary cirrhosis is a disease of the small bile ducts with altered immunologic responsiveness often associated with various collagen diseases."2.36Primary biliary cirrhosis as a collagen disease. ( Schaffner, F, 1979)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199016 (76.19)18.7374
1990's3 (14.29)18.2507
2000's1 (4.76)29.6817
2010's1 (4.76)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sawamura, M1
Oishi, W1
Nakanishi, E1
Maruhama, S1
Kim, G1
Harada, K1
ter Borg, EJ1
Haanen, HC1
Haas, FJ1
Bistervels, JH1
Huisman, FW1
Kerckhaert, JA1
Kallenberg, CG1
Chalès, G1
Fauchet, R1
Pawlotsky, Y1
Gueguen, M1
Coutard, J1
Duval, A1
Pittie, P1
Stastny, P1
Griffin, AJ1
Wooley, P1
Panayi, GS1
Batchelor, JR1
Moutsopoulos, HM2
Giotaki, H1
Maddison, PJ1
Mavridis, AC1
Drosos, AA1
Skopouli, FN2
Chuah, SY1
Wong, NW1
Goh, KL1
Asahina, M2
Kuwabara, S1
Nakajima, M1
Hattori, T1
Corke, CF1
Huskisson, EC1
Schaffner, F1
Wallach, D1
Pecking, A1
Delvincourt, C1
Cottenot, F1
Najean, Y1
Cucher, BG1
Goldman, AL1
Dohi, K1
Morita, H1
Muzellec, Y1
Le Goff, P2
Jouquan, J2
Fauquert, P1
Muller, S2
Youinou, P2
Lelong, A1
Andonopoulos, AP1
Dugowson, CE1
Gilliland, BC1
Lakhanpal, S1
Duffy, J1
Griffing, WL1
Conn, DL1
Luthra, HS1
Blaylock, WM1
Waller, M1
Normansell, DE1
Machtey, I1

Reviews

3 reviews available for penicillamine and Sjogren's Syndrome

ArticleYear
Rheumatoid arthritis: relationship with HLA-D.
    The American journal of medicine, 1983, Dec-30, Volume: 75, Issue:6A

    Topics: Adult; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Diabetes Mellitus, Type 1; Felty Syndrome;

1983
Primary biliary cirrhosis as a collagen disease.
    Postgraduate medicine, 1979, Volume: 65, Issue:6

    Topics: Adrenal Cortex Hormones; Antibodies; Antigen-Antibody Complex; Aspirin; Collagen Diseases; Complemen

1979
Management of rheumatoid arthritis.
    Disease-a-month : DM, 1986, Volume: 32, Issue:1

    Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyc

1986

Other Studies

18 other studies available for penicillamine and Sjogren's Syndrome

ArticleYear
[Case of ataxic sensory neuronopathy associated with Sjögren's syndrome].
    Rinsho shinkeigaku = Clinical neurology, 2014, Volume: 54, Issue:5

    Topics: Aged; Ataxia; Female; Ganglia, Spinal; Humans; Neuritis; Nursing Administration Research; Penicillam

2014
Treatment of primary Sjögren's syndrome with D-penicillamine: a pilot study.
    The Netherlands journal of medicine, 2002, Volume: 60, Issue:10

    Topics: Adult; Aged; Antirheumatic Agents; Drug Evaluation; Female; Humans; Male; Middle Aged; Netherlands;

2002
[The HLA-DR determinants in chronic inflammatory rheumatism].
    Revue du rhumatisme et des maladies osteo-articulaires, 1983, Volume: 50, Issue:7

    Topics: Adult; Aged; Arthritis, Rheumatoid; Chondrocalcinosis; Drug Hypersensitivity; Epitopes; Female; Gold

1983
HLA DR antigens and disease expression in rheumatoid arthritis.
    Annals of the rheumatic diseases, 1984, Volume: 43, Issue:2

    Topics: Arthritis, Rheumatoid; Female; Gold Sodium Thiomalate; Histocompatibility Antigens Class II; HLA-DR

1984
Antibodies to cellular antigens in Greek patients with autoimmune rheumatic diseases: anti-Ro(SSA) antibody a possible marker of penicillamine-D intolerance.
    Annals of the rheumatic diseases, 1984, Volume: 43, Issue:2

    Topics: Adult; Aged; Antigens; Arthritis, Rheumatoid; Autoantibodies; Autoantigens; Autoimmune Diseases; Fem

1984
Lethargy in a patient with cirrhosis.
    Postgraduate medical journal, 1997, Volume: 73, Issue:857

    Topics: Female; Humans; Hyperthyroidism; Liver Cirrhosis, Biliary; Middle Aged; Myasthenia Gravis; Penicilla

1997
D-penicillamine treatment for chronic sensory ataxic neuropathy associated with Sjögren's syndrome.
    Neurology, 1998, Volume: 51, Issue:5

    Topics: Adult; Antirheumatic Agents; Ataxia; Evoked Potentials, Somatosensory; Female; Humans; Median Nerve;

1998
Penicillamine and previous treatment with gold.
    British medical journal, 1978, Aug-26, Volume: 2, Issue:6137

    Topics: Arthritis, Rheumatoid; Bone Marrow Diseases; Drug Eruptions; Gold; Humans; Penicillamine; Sjogren's

1978
Factors affecting the development of penicillamine side-effects.
    Rheumatology and rehabilitation, 1978, Volume: 17, Issue:1

    Topics: Agglutination Tests; Antibodies, Antinuclear; Arthritis, Rheumatoid; Humans; Immunoglobulins; Latex

1978
[Gougerot-Sjögren's syndrome and pemphigus. Parallel development of the dryness syndrome and auto-immune dermatosis].
    Annales de dermatologie et de venereologie, 1979, Volume: 106, Issue:2

    Topics: Adult; Autoimmune Diseases; Humans; Male; Pemphigus; Penicillamine; Salivary Glands; Sjogren's Syndr

1979
D-penicillamine-induced polymyositis in rheumatoid arthritis.
    Annals of internal medicine, 1976, Volume: 85, Issue:5

    Topics: Arthritis, Rheumatoid; Bundle-Branch Block; Electromyography; Female; Humans; Middle Aged; Myositis;

1976
[Progress on diagnosis and therapy of kidney diseases complicated with rheumatoid arthritis and Sjogren's syndrome].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Jan-10, Volume: 81, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Gold; Humans; Kidney Diseases; Penic

1992
Antibodies to histones in rheumatoid arthritis.
    Diagnostic and clinical immunology, 1988, Volume: 5, Issue:6

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Arthritis, Rheumatoid; Enzyme-Link

1988
[Among the antinuclear antibodies in rheumatoid polyarthritis: antihistone antibodies detected by an immunoenzymatic technic].
    Revue du rhumatisme et des maladies osteo-articulaires, 1988, Volume: 55, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Arthritis, Rheumatoid; Enzyme-Linked Immuno

1988
Clinical implications of the presence of anti-Ro (SSA) antibodies in patients with rheumatoid arthritis.
    Journal of autoimmunity, 1988, Volume: 1, Issue:4

    Topics: Adult; Aged; Antibodies, Antinuclear; Arthritis, Rheumatoid; Greece; Humans; Lupus Erythematosus, Sy

1988
Sjögren's syndrome: treatment with D-penicillamine and hydroxychloroquine.
    The Journal of rheumatology, 1985, Volume: 12, Issue:5

    Topics: Adult; Aged; Female; Humans; Hydroxychloroquine; Middle Aged; Penicillamine; Sjogren's Syndrome

1985
Sjögren's syndrome: hyperviscosity and intermediate complexes.
    Annals of internal medicine, 1974, Volume: 80, Issue:1

    Topics: Antigen-Antibody Complex; Blood Protein Electrophoresis; Blood Viscosity; Chlorambucil; Chromatograp

1974
[Subclavian steal syndrome associated with Sjögren's syndrome].
    Harefuah, 1973, Aug-15, Volume: 85, Issue:4

    Topics: Adult; Humans; Middle Aged; Penicillamine; Sjogren's Syndrome; Subclavian Steal Syndrome

1973