penicillamine has been researched along with Sjogren's Syndrome in 21 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Sjogren's Syndrome: Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Conditions often associated with rheumatoid arthritis and also thought to have an immunologic basis, such as Sjögren's syndrome, Felty's syndrome, and rheumatoid vasculitis, and reactions to medications, such as gold and penicillamine, reveal an interesting spectrum of immunogenetic relationships." | 4.76 | Rheumatoid arthritis: relationship with HLA-D. ( Stastny, P, 1983) |
| "Characteristics of patients on penicillamine therapy for rheumatoid arthritis were correlated with the occurrence of different side-effects." | 3.66 | Factors affecting the development of penicillamine side-effects. ( Corke, CF; Huskisson, EC, 1978) |
| "Primary biliary cirrhosis is a disease of the small bile ducts with altered immunologic responsiveness often associated with various collagen diseases." | 2.36 | Primary biliary cirrhosis as a collagen disease. ( Schaffner, F, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (76.19) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sawamura, M | 1 |
| Oishi, W | 1 |
| Nakanishi, E | 1 |
| Maruhama, S | 1 |
| Kim, G | 1 |
| Harada, K | 1 |
| ter Borg, EJ | 1 |
| Haanen, HC | 1 |
| Haas, FJ | 1 |
| Bistervels, JH | 1 |
| Huisman, FW | 1 |
| Kerckhaert, JA | 1 |
| Kallenberg, CG | 1 |
| Chalès, G | 1 |
| Fauchet, R | 1 |
| Pawlotsky, Y | 1 |
| Gueguen, M | 1 |
| Coutard, J | 1 |
| Duval, A | 1 |
| Pittie, P | 1 |
| Stastny, P | 1 |
| Griffin, AJ | 1 |
| Wooley, P | 1 |
| Panayi, GS | 1 |
| Batchelor, JR | 1 |
| Moutsopoulos, HM | 2 |
| Giotaki, H | 1 |
| Maddison, PJ | 1 |
| Mavridis, AC | 1 |
| Drosos, AA | 1 |
| Skopouli, FN | 2 |
| Chuah, SY | 1 |
| Wong, NW | 1 |
| Goh, KL | 1 |
| Asahina, M | 2 |
| Kuwabara, S | 1 |
| Nakajima, M | 1 |
| Hattori, T | 1 |
| Corke, CF | 1 |
| Huskisson, EC | 1 |
| Schaffner, F | 1 |
| Wallach, D | 1 |
| Pecking, A | 1 |
| Delvincourt, C | 1 |
| Cottenot, F | 1 |
| Najean, Y | 1 |
| Cucher, BG | 1 |
| Goldman, AL | 1 |
| Dohi, K | 1 |
| Morita, H | 1 |
| Muzellec, Y | 1 |
| Le Goff, P | 2 |
| Jouquan, J | 2 |
| Fauquert, P | 1 |
| Muller, S | 2 |
| Youinou, P | 2 |
| Lelong, A | 1 |
| Andonopoulos, AP | 1 |
| Dugowson, CE | 1 |
| Gilliland, BC | 1 |
| Lakhanpal, S | 1 |
| Duffy, J | 1 |
| Griffing, WL | 1 |
| Conn, DL | 1 |
| Luthra, HS | 1 |
| Blaylock, WM | 1 |
| Waller, M | 1 |
| Normansell, DE | 1 |
| Machtey, I | 1 |
3 reviews available for penicillamine and Sjogren's Syndrome
| Article | Year |
|---|---|
Rheumatoid arthritis: relationship with HLA-D.
Topics: Adult; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Diabetes Mellitus, Type 1; Felty Syndrome; | 1983 |
Primary biliary cirrhosis as a collagen disease.
Topics: Adrenal Cortex Hormones; Antibodies; Antigen-Antibody Complex; Aspirin; Collagen Diseases; Complemen | 1979 |
Management of rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Juvenile; Arthritis, Rheumatoid; Azathioprine; Chloroquine; Cyc | 1986 |
18 other studies available for penicillamine and Sjogren's Syndrome
| Article | Year |
|---|---|
[Case of ataxic sensory neuronopathy associated with Sjögren's syndrome].
Topics: Aged; Ataxia; Female; Ganglia, Spinal; Humans; Neuritis; Nursing Administration Research; Penicillam | 2014 |
Treatment of primary Sjögren's syndrome with D-penicillamine: a pilot study.
Topics: Adult; Aged; Antirheumatic Agents; Drug Evaluation; Female; Humans; Male; Middle Aged; Netherlands; | 2002 |
[The HLA-DR determinants in chronic inflammatory rheumatism].
Topics: Adult; Aged; Arthritis, Rheumatoid; Chondrocalcinosis; Drug Hypersensitivity; Epitopes; Female; Gold | 1983 |
HLA DR antigens and disease expression in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Female; Gold Sodium Thiomalate; Histocompatibility Antigens Class II; HLA-DR | 1984 |
Antibodies to cellular antigens in Greek patients with autoimmune rheumatic diseases: anti-Ro(SSA) antibody a possible marker of penicillamine-D intolerance.
Topics: Adult; Aged; Antigens; Arthritis, Rheumatoid; Autoantibodies; Autoantigens; Autoimmune Diseases; Fem | 1984 |
Lethargy in a patient with cirrhosis.
Topics: Female; Humans; Hyperthyroidism; Liver Cirrhosis, Biliary; Middle Aged; Myasthenia Gravis; Penicilla | 1997 |
D-penicillamine treatment for chronic sensory ataxic neuropathy associated with Sjögren's syndrome.
Topics: Adult; Antirheumatic Agents; Ataxia; Evoked Potentials, Somatosensory; Female; Humans; Median Nerve; | 1998 |
Penicillamine and previous treatment with gold.
Topics: Arthritis, Rheumatoid; Bone Marrow Diseases; Drug Eruptions; Gold; Humans; Penicillamine; Sjogren's | 1978 |
Factors affecting the development of penicillamine side-effects.
Topics: Agglutination Tests; Antibodies, Antinuclear; Arthritis, Rheumatoid; Humans; Immunoglobulins; Latex | 1978 |
[Gougerot-Sjögren's syndrome and pemphigus. Parallel development of the dryness syndrome and auto-immune dermatosis].
Topics: Adult; Autoimmune Diseases; Humans; Male; Pemphigus; Penicillamine; Salivary Glands; Sjogren's Syndr | 1979 |
D-penicillamine-induced polymyositis in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Bundle-Branch Block; Electromyography; Female; Humans; Middle Aged; Myositis; | 1976 |
[Progress on diagnosis and therapy of kidney diseases complicated with rheumatoid arthritis and Sjogren's syndrome].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Gold; Humans; Kidney Diseases; Penic | 1992 |
Antibodies to histones in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Arthritis, Rheumatoid; Enzyme-Link | 1988 |
[Among the antinuclear antibodies in rheumatoid polyarthritis: antihistone antibodies detected by an immunoenzymatic technic].
Topics: Adult; Aged; Aged, 80 and over; Antibodies, Antinuclear; Arthritis, Rheumatoid; Enzyme-Linked Immuno | 1988 |
Clinical implications of the presence of anti-Ro (SSA) antibodies in patients with rheumatoid arthritis.
Topics: Adult; Aged; Antibodies, Antinuclear; Arthritis, Rheumatoid; Greece; Humans; Lupus Erythematosus, Sy | 1988 |
Sjögren's syndrome: treatment with D-penicillamine and hydroxychloroquine.
Topics: Adult; Aged; Female; Humans; Hydroxychloroquine; Middle Aged; Penicillamine; Sjogren's Syndrome | 1985 |
Sjögren's syndrome: hyperviscosity and intermediate complexes.
Topics: Antigen-Antibody Complex; Blood Protein Electrophoresis; Blood Viscosity; Chlorambucil; Chromatograp | 1974 |
[Subclavian steal syndrome associated with Sjögren's syndrome].
Topics: Adult; Humans; Middle Aged; Penicillamine; Sjogren's Syndrome; Subclavian Steal Syndrome | 1973 |