penicillamine has been researched along with Sclerosis, Systemic in 237 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Excerpt | Relevance | Reference |
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"The use of penicillamine in the treatment of rheumatoid arthritis and scheroderma is reviewed." | 9.04 | The use of penicillamine in the treatment of rheumatoid arthritis and scleroderma. ( Baum, J, 1979) |
"D-penicillamine-associated bronchiolitis obliterans (BO) is a rare but well-known pulmonary complication in patients with rheumatoid arthritis or progressive systemic sclerosis." | 8.79 | Bronchiolitis obliterans in a patient with localized scleroderma treated with D-penicillamine. ( Boehler, A; Russi, EW; Speich, R; Vogt, P; Weder, W, 1996) |
"A case of a bullous eruption occurred in a patient being treated with penicillamine for sclerodermatous graft-versus-host disease following bone marrow transplantation." | 7.72 | Epidermolysis bullosa acquisita-like reaction associated with penicillamine therapy for sclerodermatous graft-versus-host disease. ( Cetkovská, P; Pizinger, K; Skálová, A, 2003) |
"D: -Penicillamine-induced pemphigus occurs infrequently, typically in patients with rheumatoid arthritis." | 7.70 | Pemphigus vulgaris induced by D-penicillamine therapy in a patient with systemic sclerosis. ( Jimenez, S; Shapiro, M; Werth, VP, 2000) |
" Both patients (one case of progressive systemic sclerosis and one of rheumatoid arthritis) were currently taking D-penicillamine." | 7.68 | Unilateral ptosis as an initial manifestation of D-penicillamine induced myasthenia gravis. ( Fries, JF; Kornfeld, P; Lee, YS; Raynauld, JP, 1993) |
"A 56-year-old woman with scleroderma developed rapidly progressive glomerulonephritis with epithelial crescents associated with hemoptysis after 27 months of D-penicillamine therapy and a cumulative dose of 1,200 g." | 7.67 | D-penicillamine induced crescentic glomerulonephritis: report and review of the literature. ( Brichard, S; Cosyns, JP; Devogelaer, JP; Nagant de Deuxchaisnes, C; Pirson, Y; Vandenbroucke, JM, 1987) |
"The development of autoimmune diseases in some patients treated with D-penicillamine (DPA) suggests that the reported occurrence of a conduction disorder at the neuromuscular junction and the development of a reversible myasthenia gravis in rheumatoid disease, progressive systemic sclerosis or Wilson's disease after the use of DPA are part of a general predisposition for autoimmune disease related to DPA therapy." | 7.67 | [Myasthenia gravis induced by D-penicillamine in a patient with progressive systemic sclerosis]. ( Cossermelli, W; De Assis, JL; Marchiori, PE; Scaff, M, 1984) |
"5 patients suffering from progressive scleroderma with interstitial pulmonary fibrosis have been treated since 1971 with D-penicillamine (Artamin) as basic therapeutic agent." | 7.65 | [Treatment of interstitial pulmonary fibrosis with D-penicillamine in progressive scleroderma: a long-term study (author's transl)]. ( Bröll, H; Eberl, R; Tausch, G, 1976) |
"Proteinuria is observed in 10% of the patients, often secondary to extramembranous glomerulopathy." | 5.30 | [Extracapillary glomerulonephritis with anti-myeloperoxidase antibodies in 2 patients with systemic scleroderma treated with penicillamine D]. ( Bridoux, F; Ducq, P; Gheerbrant, JD; Kyndt, X; Makdassi, R; Reumaux, D; Vanhille, P, 1999) |
"Immune thrombocytopenia is a rare complication of progressive systemic sclerosis (PSS)." | 5.28 | Progressive systemic sclerosis complicated with immune thrombocytopenia during D-penicillamine therapy. ( Kashiwagi, H; Kato, S; Kono, I; Matsui, Y; Natsuda, H; Sakauchi, M; Suzuki, H; Takemura, H; Yamane, K, 1992) |
"The use of penicillamine in the treatment of rheumatoid arthritis and scheroderma is reviewed." | 5.04 | The use of penicillamine in the treatment of rheumatoid arthritis and scleroderma. ( Baum, J, 1979) |
"We report the case of a 34-year-old white woman with a history of progressive systemic scleroderma (PSS) and diffuse alveolar hemorrhage (DAH) that may be either a rare complication of PSS or induced by D-penicillamine." | 4.80 | A case study and national database report of progressive systemic sclerosis and associated conditions. ( Mannino, D; Phillips, B; Phillips, D, 1998) |
"D-penicillamine-associated bronchiolitis obliterans (BO) is a rare but well-known pulmonary complication in patients with rheumatoid arthritis or progressive systemic sclerosis." | 4.79 | Bronchiolitis obliterans in a patient with localized scleroderma treated with D-penicillamine. ( Boehler, A; Russi, EW; Speich, R; Vogt, P; Weder, W, 1996) |
" We report a case of a patient affected by SS, with isolated pulmonary hypertension, who developed bronchiolitis secondary to penicillamine." | 3.73 | Pulmonary involvement in systemic sclerosis due to therapy and as a complication. ( Chiappini, F; Maugeri, L; Zoli, A, 2005) |
"A case of a bullous eruption occurred in a patient being treated with penicillamine for sclerodermatous graft-versus-host disease following bone marrow transplantation." | 3.72 | Epidermolysis bullosa acquisita-like reaction associated with penicillamine therapy for sclerodermatous graft-versus-host disease. ( Cetkovská, P; Pizinger, K; Skálová, A, 2003) |
"A 66-year-old Japanese woman with severe scleroderma developed anemia and thrombocytopenia due to D-penicillamine (D-Pen) treatment, although the leukopenia was not markedly severe." | 3.70 | In vitro inhibition of hematopoiesis in a patient with systemic sclerosis treated with D-penicillamine. ( Katayama, Y; Kohriyama, K; Matsui, T, 1999) |
"D: -Penicillamine-induced pemphigus occurs infrequently, typically in patients with rheumatoid arthritis." | 3.70 | Pemphigus vulgaris induced by D-penicillamine therapy in a patient with systemic sclerosis. ( Jimenez, S; Shapiro, M; Werth, VP, 2000) |
"A case of drug-provoked fever is described in a scleroderma patient on penicillamine." | 3.68 | [Fever caused by penicillin. Description of a clinical case]. ( Baratta, E; Biscarini, L, 1990) |
" Both patients (one case of progressive systemic sclerosis and one of rheumatoid arthritis) were currently taking D-penicillamine." | 3.68 | Unilateral ptosis as an initial manifestation of D-penicillamine induced myasthenia gravis. ( Fries, JF; Kornfeld, P; Lee, YS; Raynauld, JP, 1993) |
"The development of autoimmune diseases in some patients treated with D-penicillamine (DPA) suggests that the reported occurrence of a conduction disorder at the neuromuscular junction and the development of a reversible myasthenia gravis in rheumatoid disease, progressive systemic sclerosis or Wilson's disease after the use of DPA are part of a general predisposition for autoimmune disease related to DPA therapy." | 3.67 | [Myasthenia gravis induced by D-penicillamine in a patient with progressive systemic sclerosis]. ( Cossermelli, W; De Assis, JL; Marchiori, PE; Scaff, M, 1984) |
"A 56-year-old woman with scleroderma developed rapidly progressive glomerulonephritis with epithelial crescents associated with hemoptysis after 27 months of D-penicillamine therapy and a cumulative dose of 1,200 g." | 3.67 | D-penicillamine induced crescentic glomerulonephritis: report and review of the literature. ( Brichard, S; Cosyns, JP; Devogelaer, JP; Nagant de Deuxchaisnes, C; Pirson, Y; Vandenbroucke, JM, 1987) |
"Histological, immunohistological and electron microscopical investigations on the glomerular renal lesions in penicillamine-induced nephropathy were carried out by studying biopsy material of eight patients with rheumatoid arthritis (4 cases), allergic alveolitis (3 cases) and systemic scleroderma (1 case) under the treatment with D-penicillamine." | 3.66 | [Morphology and pathogenesis of penicillamine-induced nephropathy]. ( Henzgen, S; Waldmann, G, 1983) |
"The taste function and the zinc and copper levels in serum and urine were followed for up tp 16 weeks in ten patients who were started on penicillamine therapy for generalized scleroderma (9 patients) and rheumatoid arthritis (one patient)." | 3.66 | Taste dysfunction and changes in zinc and copper metabolism during penicillamine therapy for generalized scleroderma. ( Knudsen, L; Weismann, K, 1978) |
"5 patients suffering from progressive scleroderma with interstitial pulmonary fibrosis have been treated since 1971 with D-penicillamine (Artamin) as basic therapeutic agent." | 3.65 | [Treatment of interstitial pulmonary fibrosis with D-penicillamine in progressive scleroderma: a long-term study (author's transl)]. ( Bröll, H; Eberl, R; Tausch, G, 1976) |
"The spectrum of kidney involvement in systemic sclerosis (SSc) includes scleroderma renal crisis, widely recognized as the most severe renal-vascular complication, but also several forms of chronic renal vasculopathy and reduced renal function are complications of scleroderma." | 2.82 | Assessment of kidney involvement in systemic sclerosis: From scleroderma renal crisis to subclinical renal vasculopathy. ( Gigante, A; Leodori, G; Pellicano, C; Rosato, E; Villa, A, 2022) |
"To test the hypothesis that systemic sclerosis (SSc) patients taking high-dose D-penicillamine (D-Pen) would have greater softening of skin, lower frequency of renal crisis, and better survival than patients taking low-dose D-Pen." | 2.69 | High-dose versus low-dose D-penicillamine in early diffuse systemic sclerosis: analysis of a two-year, double-blind, randomized, controlled clinical trial. ( Abeles, M; Andrews, B; Barr, W; Clements, PJ; Collier, D; Furst, DE; Lally, E; Martin, RW; Mayes, M; Medsger, TA; Moreland, LW; Seibold, JR; Steen, V; Varga, J; Weiner, S; Weinstein, A; Weisman, MH; White, B; Wigley, F; Wong, WK, 1999) |
"For patients with systemic sclerosis of recent onset, extracorporeal photochemotherapy is a well-tolerated treatment that may partially reverse the process that results in cutaneous sclerosis." | 2.67 | Treatment of systemic sclerosis with extracorporeal photochemotherapy. Results of a multicenter trial. ( Barr, WG; Freundlich, B; Jegasothy, BV; Jimenez, SA; Kahaleh, MB; Perez, MI; Rietschel, RL; Rook, AH; Varga, J; Wintroub, B, 1992) |
"Although rare, vasculitis is a complication of SSc." | 2.49 | Systemic vasculitis during the course of systemic sclerosis: report of 12 cases and review of the literature. ( Cacoub, P; Guillevin, L; Hachulla, E; Hatron, PY; Meyer, O; Michon-Pasturel, U; Mouthon, L; Quéméneur, T; Vanhille, P, 2013) |
"The use of D-penicillamine in systemic sclerosis (SSc) has been controversial." | 2.41 | D-penicillamine in systemic sclerosis? Yes! ( Baker, C; Lucas, M; Medsger, TA; Wildy, KS, 2001) |
" The course of skin thickening and the occurrence of renal crisis and of death were examined in a recent randomized controlled 2-year trial of high- dosage DPA (750-1000 mg/d) versus low-dose DPA (125 mg every other day)." | 2.40 | Penicillamine in the treatment of systemic sclerosis. ( Clements, PJ, 1999) |
"Although the aetiology of systemic sclerosis is unknown, its prevalence has been reported to be increased in workers exposed to silica." | 2.39 | [Systemic sclerosis]. ( Gustafsson, R, 1994) |
"Systemic scleroderma is an acquired disorder which typically results in fibrosis of the skin and internal organs." | 2.38 | Activation of dermal connective tissue in scleroderma. ( Kähäri, VM, 1993) |
"None of the patients with morphea had a history of thyroid pathology and the thyroid screenings were within normal limits." | 2.38 | [Scleroderma and thyroid diseases]. ( Claudy, A; Mourier-Clavreul, MC; Rousset, H, 1989) |
"After 6 years of follow-up, the mesenteric panniculitis and systemic sclerosis both remained stable." | 1.40 | Limited systemic sclerosis initially presenting with mesenteric panniculitis. ( Arroyo-Ávila, M; Vilá, LM, 2014) |
"Localized disease manifests as patches (morphea) or bandlike (linear scleroderma) areas of skin thickening." | 1.35 | Diagnosis and treatment of scleroderma. ( Adnan, ZA, 2008) |
"We report a case of diffuse systemic sclerosis (skin, joints, esophagus, and Raynaud's phenomenon) in a 41-year-old Caucasian male with a 15-year history of ankylosing spondylitis and an episode of severe myocarditis of unknown origin." | 1.35 | Ankylosing spondylitis and systemic sclerosis: a rare combination. ( Meyer, O; Nlomé-Nzé, M; Ouédraogo, DD; Palazzo, E; Somogyi-Demerjian, N, 2009) |
"Co-occurence of systemic sclerosis and collagenous colitis is particularly rare." | 1.34 | Collagenous colitis in a patient with systemic sclerosis: a rare entity. ( Coban, S; Ekiz, F; Ensari, A; Gören, D; Ormeci, N; Savas, B, 2007) |
"The connective tissue disease systemic sclerosis (SSc) is still a challenge to every rheumatologist." | 1.33 | [Systemic sclerosis--a challenge in rheumatology]. ( Müller-Ladner, U; Saar, P, 2006) |
"She was diagnosed as having systemic sclerosis (SSc) based on the skin sclerosis of her arms, chest, and face." | 1.32 | Improvement of skin sclerosis after occurrence of anticentromere antibody in a patient with diffuse cutaneous systemic sclerosis. ( Echigo, T; Hasegawa, M; Hayakawa, I; Sato, S; Shirasaki, F; Takehara, K, 2004) |
"We describe three patients with minimal change nephrotic syndrome associated with penicillamine treatment." | 1.32 | [Minimal changes nephrotic syndrome associated to penicillamine treatment]. ( Basterrechea, MA; de Arriba, G; García-Martín, F; Giménez-Vega, E; Sánchez, J; Sánchez-Heras, M, 2004) |
"Progressive systemic sclerosis (PSS), or scleroderma, is a rare disease in the pediatric population." | 1.31 | Clinical trials for pediatric scleroderma. ( Lehman, TJ; Rosenkranz, ME, 2002) |
"To evaluate functional impairment in systemic sclerosis (SSc) patients with diffuse cutaneous scleroderma at the time of entry into a trial of a therapeutic intervention (D-penicillamine)." | 1.30 | Correlates of the disability index of the health assessment questionnaire: a measure of functional impairment in systemic sclerosis. ( Abeles, M; Andrews, B; Barr, W; Clements, PJ; Collier, D; Furst, DE; Hurwitz, EL; Lally, E; Martin, R; Mayes, M; Medsger, TA; Moreland, L; Seibold, J; Steen, V; Varga, J; Weiner, S; Weinstein, A; Weisman, M; White, B; Wigley, F; Wong, WK, 1999) |
"Proteinuria is observed in 10% of the patients, often secondary to extramembranous glomerulopathy." | 1.30 | [Extracapillary glomerulonephritis with anti-myeloperoxidase antibodies in 2 patients with systemic scleroderma treated with penicillamine D]. ( Bridoux, F; Ducq, P; Gheerbrant, JD; Kyndt, X; Makdassi, R; Reumaux, D; Vanhille, P, 1999) |
"Progressive renal failure in patients with scleroderma is a sinister development that is usually attributed to impaired renal blood flow." | 1.30 | Scleroderma, D-penicillamine treatment, and progressive renal failure associated with positive antimyeloperoxidase antineutrophil cytoplasmic antibodies. ( Hillis, GS; Khan, IH; Rees, AJ; Simpson, JG, 1997) |
"Sera from 97 patients and suction blister fluid from 13 patients were radioimmunoassayed." | 1.29 | The use of serologic markers for collagen synthesis and degradation in systemic sclerosis. ( Bjerring, P; Halkier-Sørensen, L; Heickendorff, L; Søndergaard, K; Zachariae, H, 1995) |
"There was a significant association of trauma with childhood-onset scleroderma (P < 0." | 1.29 | Childhood-onset scleroderma: is it different from adult-onset disease. ( Atherton, D; Black, CM; David, J; Harper, J; Hasson, N; Trivedi, P; Vancheeswaran, R; Woo, P, 1996) |
"A case of systemic sclerosis (SS) which developed keloidal lesions (nodular scleroderma) on the chest during D-penicillamine (DPC) therapy is reported." | 1.28 | Nodular scleroderma in systemic sclerosis under D-penicillamine therapy. ( Denpo, K; Nakajima, H; Ono, H; Sasaki, T, 1992) |
"Immune thrombocytopenia is a rare complication of progressive systemic sclerosis (PSS)." | 1.28 | Progressive systemic sclerosis complicated with immune thrombocytopenia during D-penicillamine therapy. ( Kashiwagi, H; Kato, S; Kono, I; Matsui, Y; Natsuda, H; Sakauchi, M; Suzuki, H; Takemura, H; Yamane, K, 1992) |
"A 45-year-old woman had recurrent morphea lesions over 10 times in 6 years." | 1.28 | Palindromic morphea: multiple recurrence of morphea lesions in a case of systemic sclerosis. ( Mizutani, H; Mizutani, T; Okada, H; Shimizu, M; Tanaka, H, 1992) |
"In all patients with diffuse systemic sclerosis there was objective improvement." | 1.28 | Penicillamine in systemic sclerosis: a reappraisal. ( Guindi, RT; Sattar, MA; Sugathan, TN, 1990) |
"A 58-year-old woman with progressive systemic sclerosis developed a butterfly erythematous eruption, hemorrhagic maculae, crusting, and erosions on the face 15 days following administration of D-penicillamine." | 1.28 | Lupus erythematosus-like eruption due to D-penicillamine in progressive systemic sclerosis. ( Lazarova, AZ; Obreshkova, EV; Tsankov, NK; Vasileva, SG, 1990) |
" Urinary excretion of the collagen-specific amino acids hydroxyproline and hydroxylysine, and of proline was used as a guideline for monitoring the bioavailability of D-penicillamine." | 1.28 | The progress of oesophageal involvement in progressive systemic sclerosis during D-penicillamine treatment. ( Aggestrup, S; Hendel, L; Stentoft, P, 1989) |
" Adverse effects occurred more frequently after rapid increases in dosage." | 1.27 | The toxicity of D-penicillamine in systemic sclerosis. ( Blair, S; Medsger, TA; Steen, VD, 1986) |
"The bioavailability of D-penicillamine was measured in 24 patients with generalized scleroderma (Progressive Systemic Sclerosis, PSS)." | 1.27 | Bioavailability of D-penicillamine in relation to gastrointestinal involvement of generalized scleroderma. ( Ammitzbøll, T; Asboe-Hansen, G; Hendel, L; Kreuzig, F, 1987) |
"Tiopronine was tried in 4 of these patients with 3 interpretables follow-ups." | 1.27 | [Treatment of systemic scleroderma with D-penicillamine. Results in 14 patients treated for more than a year]. ( Bourgeois, P; Brion, N; Elleuch, M; Kahn, MF, 1986) |
" This is the first case reported in which long-term administration of penicillamine was followed by the development of systemic sclerosis-like lesions." | 1.27 | Systemic sclerosis-like lesions during long-term penicillamine therapy for Wilson's disease. ( Hatoko, M; Miyagawa, S; Okuchi, T; Sakamoto, K; Yoshioka, A, 1987) |
" D-penicillamine bioavailability was examined after oral, duodenal, intravenous and rectal administration." | 1.27 | Bioavailability of D-penicillamine in a patient with gastrointestinal progressive systemic sclerosis. ( Ammitzbøll, T; Asboe-Hansen, G; Hendel, L; Kreuzig, F; Worning, H, 1986) |
"Forty-four systemic sclerosis patients who received a mean dose of 636 mg of D-penicillamine for 2." | 1.27 | The effect of D-penicillamine on pulmonary findings in systemic sclerosis. ( Medsger, TA; Owens, GR; Redmond, C; Rodnan, GP; Steen, VD, 1985) |
"Treatment with danazol was associated with a reduction in both the breast size and the prolactin level." | 1.27 | Massive breast enlargement in a patient receiving D-penicillamine for systemic sclerosis. ( Kahl, LE; Klein, I; Medsger, TA, 1985) |
"Twenty-two patients with progressive systemic sclerosis were treated with D-penicillamine in doses ranging up to 1250 mg/day for periods varying between a few months and four years." | 1.26 | Penicillamine therapy in systemic sclerosis. ( Black, CM; Jayson, MI; Lovell, C; Wilson, RS, 1977) |
"A case of severe diffuse systemic sclerosis with cardiomegaly and cardiac failure is described." | 1.26 | Treatment of scleroderma heart by D-penicillamine. ( Muers, M; Stokes, W, 1976) |
"Four patients with systemic sclerosis (scleroderma) were treated with (D)-penicillamine (1." | 1.26 | (D)-penicillamine treatment in systemic sclerosis (scleroderma). Effect on nutritional capillary circulation. ( Björkholm, M; Fagrell, B; Holm, G; Mellstedt, H, 1977) |
"In a retrospective study on progressive systemic sclerosis, we compared 73 patients who had received D-penicillamine therapy for a minimum of 6 consecutive months with 45 patients who had not received this drug." | 1.26 | D-Penicillamine therapy in progressive systemic sclerosis (scleroderma): a retrospective analysis. ( Medsger, TA; Rodnan, GP; Steen, VD, 1982) |
"A 25-year-old woman with progressive systemic sclerosis was treated with D-penicillamine." | 1.26 | [Cholestatic jaundice induced by D-penicillamine and oral steroid contraceptive in progressive systemic sclerosis (author's transl)]. ( Julius, U; Wozel, G, 1982) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 129 (54.43) | 18.7374 |
1990's | 61 (25.74) | 18.2507 |
2000's | 40 (16.88) | 29.6817 |
2010's | 5 (2.11) | 24.3611 |
2020's | 2 (0.84) | 2.80 |
Authors | Studies |
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Gigante, A | 1 |
Leodori, G | 1 |
Pellicano, C | 1 |
Villa, A | 1 |
Rosato, E | 1 |
Atzori, L | 1 |
Ferreli, C | 1 |
Agosta, D | 1 |
Mou, M | 1 |
Coni, P | 1 |
Lachowicz, JI | 1 |
Pilloni, L | 1 |
Arroyo-Ávila, M | 1 |
Vilá, LM | 1 |
Chabra, IS | 1 |
Grandinetti, LM | 1 |
Bennett, JA | 1 |
Clarke, JT | 1 |
Ioffreda, MD | 1 |
Adnan, ZA | 1 |
Ouédraogo, DD | 1 |
Palazzo, E | 1 |
Nlomé-Nzé, M | 1 |
Somogyi-Demerjian, N | 1 |
Meyer, O | 2 |
Amjadi, S | 1 |
Maranian, P | 1 |
Furst, DE | 9 |
Clements, PJ | 10 |
Wong, WK | 7 |
Postlethwaite, AE | 1 |
Khanna, PP | 1 |
Khanna, D | 1 |
Bian, H | 1 |
Fan, YS | 1 |
Lou, LH | 1 |
Mao, BY | 1 |
Shi, JY | 1 |
Poulas, K | 1 |
Koutsouraki, E | 1 |
Kordas, G | 1 |
Kokla, A | 1 |
Tzartos, SJ | 1 |
Quéméneur, T | 1 |
Mouthon, L | 3 |
Cacoub, P | 1 |
Michon-Pasturel, U | 1 |
Vanhille, P | 2 |
Hatron, PY | 1 |
Guillevin, L | 2 |
Hachulla, E | 1 |
Rosenkranz, ME | 1 |
Lehman, TJ | 1 |
Strand, V | 1 |
DeMarco, PJ | 1 |
Weisman, MH | 2 |
Seibold, JR | 6 |
Hurwitz, EL | 4 |
Mayes, M | 6 |
White, B | 6 |
Wigley, F | 6 |
Barr, W | 6 |
Moreland, L | 5 |
Medsger, TA | 18 |
Steen, V | 6 |
Martin, RW | 5 |
Collier, D | 6 |
Weinstein, A | 6 |
Lally, E | 6 |
Varga, J | 8 |
Weiner, SR | 4 |
Andrews, B | 6 |
Abeles, M | 6 |
Dourmishev, LA | 1 |
Stomonjakova, SR | 1 |
Dourmishev, AL | 1 |
Derk, CT | 1 |
Jimenez, SA | 5 |
Jinnin, M | 1 |
Ihn, H | 2 |
Asano, Y | 1 |
Yamane, K | 3 |
Yazawa, N | 1 |
Tamaki, K | 1 |
Cetkovská, P | 1 |
Pizinger, K | 1 |
Skálová, A | 1 |
Mayes, MD | 1 |
O'Donnell, D | 1 |
Rothfield, NF | 1 |
Csuka, ME | 1 |
Weisman, MD | 1 |
Alekperov, RT | 1 |
Avdeev, SN | 1 |
Kotovskaia, MA | 1 |
Basterrechea, MA | 1 |
de Arriba, G | 1 |
García-Martín, F | 1 |
Sánchez-Heras, M | 1 |
Giménez-Vega, E | 1 |
Sánchez, J | 1 |
Hayakawa, I | 1 |
Sato, S | 1 |
Echigo, T | 1 |
Shirasaki, F | 1 |
Hasegawa, M | 1 |
Takehara, K | 2 |
Szegedi, A | 1 |
Surányi, P | 1 |
Szücs, G | 1 |
Kiss, M | 1 |
Hunyadi, J | 1 |
Gaál, J | 1 |
Suematsu, E | 1 |
Miyamura, T | 1 |
Idutsu, K | 1 |
Minami, R | 1 |
Yamamoto, M | 1 |
Chiappini, F | 1 |
Zoli, A | 1 |
Maugeri, L | 1 |
Melani, L | 1 |
Caproni, M | 1 |
Cardinali, C | 1 |
Antiga, E | 1 |
Bernacchi, E | 1 |
Schincaglia, E | 1 |
Fabbri, P | 1 |
van den Hoogen, FH | 2 |
Saar, P | 1 |
Müller-Ladner, U | 1 |
Berezné, A | 1 |
Poiraudeau, S | 1 |
Ekiz, F | 1 |
Coban, S | 1 |
Savas, B | 1 |
Gören, D | 1 |
Ensari, A | 1 |
Ormeci, N | 1 |
Coyle, HE | 1 |
Chapman, RS | 1 |
Pieraggi, MT | 1 |
Bonafe, JL | 1 |
Wozel, G | 1 |
Julius, U | 1 |
Høyer, H | 1 |
Hvid-Jacobsen, K | 1 |
Weismann, K | 2 |
Hagdrup, H | 1 |
Serup, J | 1 |
Tvedegaard, E | 1 |
Jepsen, LV | 1 |
Eggert, J | 1 |
Pearson, ME | 1 |
Stechschulte, DJ | 1 |
Connolly, SM | 1 |
Priollet, P | 1 |
Baudot, N | 1 |
Fiessinger, JN | 1 |
Vayssairat, M | 1 |
Housset, E | 1 |
Priestley, GC | 1 |
Ammitzbøll, T | 4 |
Asboe-Hansen, G | 8 |
Crickx, B | 1 |
Belaich, S | 1 |
Marchiori, PE | 1 |
Scaff, M | 1 |
Cossermelli, W | 1 |
De Assis, JL | 1 |
Moutsopoulos, HM | 1 |
Giotaki, H | 1 |
Maddison, PJ | 1 |
Mavridis, AC | 1 |
Drosos, AA | 1 |
Skopouli, FN | 1 |
Henzgen, S | 1 |
Waldmann, G | 1 |
Cohen, S | 1 |
Williamson, PK | 1 |
Shapiro, LS | 1 |
Prince, RK | 1 |
Buckingham, RB | 1 |
Rodnan, GP | 3 |
Fernandes, L | 1 |
Berry, H | 1 |
Hamilton, E | 1 |
Marques Neto, JF | 1 |
Manzato, LC | 1 |
Samara, AM | 1 |
Mach, PS | 1 |
Piatier, D | 1 |
Le Go, A | 1 |
Delbarre, F | 1 |
Dovzhanskaia, VS | 1 |
Kang, B | 1 |
Veres-Thorner, C | 1 |
Heredia, R | 1 |
Cha, E | 1 |
Bose, S | 1 |
Schwartz, M | 1 |
Nemchinov, EN | 1 |
Krel', AA | 1 |
Shekhter, AB | 1 |
Rashchupkina, ZP | 1 |
Steen, VD | 6 |
Kitazawa, K | 1 |
Ohseto, Y | 1 |
Kawazumi, H | 1 |
Saito, K | 1 |
Shibata, T | 1 |
Uchida, J | 1 |
Yonekura, M | 1 |
Shiwachi, S | 1 |
Ito, S | 1 |
Sugisaki, T | 1 |
Lynggaard, F | 1 |
Mohammed, SH | 1 |
Schulze, S | 1 |
Tojo, T | 1 |
Nasonova, VA | 1 |
Alekberova, ZS | 1 |
Mach, ES | 1 |
Balabanova, RM | 3 |
Torres, CF | 1 |
Griggs, RC | 1 |
Baum, J | 2 |
Penn, AS | 1 |
Ivanova, MM | 1 |
Oskilko, TG | 3 |
Harpey, JP | 1 |
Renault, F | 1 |
Roy, C | 1 |
Lafourcade, J | 1 |
Mizutani, H | 2 |
Taniguchi, H | 1 |
Sakakura, T | 1 |
Shimizu, M | 2 |
Repnitskaia, ZD | 1 |
Tinigin, PA | 1 |
Sokolova, IIu | 1 |
Bilenko, VB | 1 |
Heickendorff, L | 1 |
Zachariae, H | 1 |
Bjerring, P | 1 |
Halkier-Sørensen, L | 1 |
Søndergaard, K | 1 |
Gustafsson, R | 1 |
Lanz, JK | 1 |
Conte, C | 1 |
Owens, GR | 3 |
Desautels, JE | 1 |
Raynauld, JP | 1 |
Lee, YS | 1 |
Kornfeld, P | 1 |
Fries, JF | 1 |
Pope, JE | 2 |
Bellamy, N | 1 |
Kähäri, VM | 1 |
Rook, AH | 3 |
Freundlich, B | 4 |
Jegasothy, BV | 2 |
Schaller, JG | 1 |
Takeuchi, F | 1 |
Nakano, K | 1 |
Yamada, H | 1 |
Kosuge, E | 1 |
Hirai, M | 1 |
Maeda, H | 1 |
Moroi, Y | 1 |
Vancheeswaran, R | 1 |
Black, CM | 3 |
David, J | 1 |
Hasson, N | 1 |
Harper, J | 1 |
Atherton, D | 1 |
Trivedi, P | 1 |
Woo, P | 1 |
Ding, C | 1 |
Zhang, X | 1 |
Bergemann, A | 1 |
Tikly, M | 1 |
Boehler, A | 1 |
Vogt, P | 1 |
Speich, R | 1 |
Weder, W | 1 |
Russi, EW | 1 |
Koh, ET | 1 |
Lee, P | 1 |
Gladman, DD | 1 |
Abu-Shakra, M | 1 |
Ortiz-Alvarez, O | 1 |
Cabral, D | 1 |
Prendiville, JS | 1 |
Stringer, D | 1 |
Petty, RE | 1 |
Malleson, PN | 1 |
Muir, TE | 1 |
Tazelaar, HD | 1 |
Colby, TV | 1 |
Myers, JL | 1 |
Zvulunov, A | 1 |
Grunwald, MH | 1 |
Avinoach, I | 1 |
Halevy, S | 1 |
Hillis, GS | 1 |
Khan, IH | 1 |
Simpson, JG | 1 |
Rees, AJ | 1 |
Fuse, Y | 1 |
Muramatsu, M | 1 |
Sugiyama, S | 1 |
Maeda, K | 1 |
Karpinski, J | 1 |
Jothy, S | 1 |
Radoux, V | 1 |
Levy, M | 1 |
Baran, D | 1 |
Barrera, P | 1 |
den Broeder, AA | 1 |
van Engelen, BG | 1 |
van de Putte, LB | 1 |
Phillips, D | 1 |
Phillips, B | 1 |
Mannino, D | 1 |
Susa, S | 1 |
Akiba, J | 1 |
Kurimura, M | 1 |
Kurita, K | 1 |
Daimon, M | 1 |
Manaka, H | 1 |
Yamatani, K | 1 |
Kato, T | 1 |
Kyndt, X | 1 |
Ducq, P | 1 |
Bridoux, F | 1 |
Reumaux, D | 1 |
Makdassi, R | 1 |
Gheerbrant, JD | 1 |
Marlier, S | 1 |
Gisserot, O | 1 |
Yao, N | 1 |
Hecht, M | 1 |
Paris, JF | 1 |
Carli, P | 1 |
Chagnon, A | 1 |
Moreland, LW | 1 |
Weiner, S | 2 |
Weisman, M | 3 |
Martin, R | 1 |
Seibold, J | 1 |
Katayama, Y | 1 |
Kohriyama, K | 1 |
Matsui, T | 1 |
Marie, I | 1 |
Lévesque, H | 1 |
Courtois, H | 1 |
Shapiro, M | 1 |
Jimenez, S | 1 |
Werth, VP | 1 |
García-Porrúa, C | 1 |
González-Gay, MA | 1 |
Bouza, P | 1 |
Saito, E | 1 |
Ogawa, T | 1 |
Ogawa, K | 1 |
Akutsu, M | 1 |
Ponor, I | 1 |
Fujita, Y | 1 |
Denton, CP | 1 |
Tanaka, M | 1 |
Tanaka, K | 1 |
Martini, A | 1 |
Lucas, M | 1 |
Wildy, KS | 1 |
Baker, C | 1 |
Agard, C | 1 |
Cozzi, F | 1 |
Marson, P | 1 |
Rosada, M | 1 |
De Silvestro, G | 1 |
Bullo, A | 1 |
Punzi, L | 1 |
Todesco, S | 1 |
Stummvoll, GH | 1 |
Guseva, NG | 4 |
Nevskaia, TA | 1 |
Starovoĭtova, MN | 1 |
Schulze, P | 1 |
Tio, TH | 1 |
Jayson, MI | 6 |
Lovell, C | 1 |
Wilson, RS | 1 |
Muers, M | 1 |
Stokes, W | 1 |
Kornreich, HK | 1 |
King, KK | 1 |
Bernstein, BH | 1 |
Singsen, BH | 1 |
Hanson, V | 1 |
Sasaki, M | 1 |
Tangsrud, SE | 1 |
Skyberg, D | 1 |
Larsen, TE | 1 |
Ansell, BM | 2 |
Knudsen, L | 1 |
Herbai, G | 1 |
Davis, P | 1 |
Bleehen, SS | 1 |
Mellstedt, H | 1 |
Fagrell, B | 1 |
Holm, G | 1 |
Björkholm, M | 1 |
Blehová, B | 1 |
Pazoutová, N | 1 |
Bröll, H | 1 |
Tausch, G | 1 |
Eberl, R | 1 |
Nasseh, GA | 1 |
Bywaters, EG | 1 |
Helmke, K | 1 |
Velcovsky, HG | 1 |
Federlin, K | 1 |
Perings, E | 1 |
Junge, U | 1 |
Moritz, AJ | 1 |
Grahame, R | 2 |
Harvey, W | 1 |
Hrncír, Z | 1 |
Tichý, M | 1 |
Sasaki, T | 1 |
Denpo, K | 1 |
Ono, H | 1 |
Nakajima, H | 1 |
Akesson, A | 2 |
Blom-Bülow, B | 1 |
Scheja, A | 2 |
Wollmer, P | 1 |
Valind, S | 1 |
Wollheim, FA | 1 |
Wigley, FM | 1 |
Perez, MI | 1 |
Barr, WG | 2 |
Rietschel, RL | 2 |
Wintroub, B | 1 |
Kahaleh, MB | 1 |
Trentham, DE | 1 |
Hørslev-Petersen, K | 1 |
Sönnichsen, N | 1 |
Brenke, A | 1 |
Natsuda, H | 1 |
Matsui, Y | 1 |
Sakauchi, M | 1 |
Kato, S | 1 |
Takemura, H | 1 |
Suzuki, H | 1 |
Kono, I | 2 |
Kashiwagi, H | 2 |
Godar, JM | 1 |
Norins, AL | 1 |
Tanaka, H | 1 |
Okada, H | 1 |
Mizutani, T | 1 |
Bourgeois, P | 2 |
Aeschlimann, A | 1 |
Wolff, DJ | 1 |
Needleman, BW | 1 |
Wasserman, SS | 1 |
Schwartz, S | 1 |
Sigal, SH | 1 |
Cooper, ES | 1 |
Santos, JC | 1 |
Velasco, JA | 1 |
Sattar, MA | 1 |
Guindi, RT | 1 |
Sugathan, TN | 1 |
Joyce, DA | 1 |
Baratta, E | 1 |
Biscarini, L | 1 |
Tsankov, NK | 1 |
Lazarova, AZ | 1 |
Vasileva, SG | 1 |
Obreshkova, EV | 1 |
Oliver, GF | 1 |
Winkelmann, RK | 2 |
Mourier-Clavreul, MC | 1 |
Rousset, H | 1 |
Claudy, A | 1 |
Hendel, L | 3 |
Stentoft, P | 1 |
Aggestrup, S | 1 |
Pevnitskiĭ, LA | 1 |
Sibiriakova, LG | 1 |
Blair, S | 1 |
Howard-Lock, HE | 1 |
Lock, CJ | 1 |
Mewa, A | 1 |
Kean, WF | 1 |
Schulze, E | 1 |
Herrmann, K | 1 |
Haustein, UF | 1 |
Krusche, U | 1 |
Rothenburger, I | 1 |
Iozumi, K | 1 |
Mori, S | 1 |
Devogelaer, JP | 1 |
Pirson, Y | 1 |
Vandenbroucke, JM | 1 |
Cosyns, JP | 1 |
Brichard, S | 1 |
Nagant de Deuxchaisnes, C | 1 |
Camus, JP | 1 |
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Grisanti, M | 1 |
Vicencio, M | 1 |
Kreuzig, F | 2 |
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Privat, Y | 1 |
de Clerck, LS | 1 |
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Demedts, M | 1 |
Gandzha, IM | 1 |
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Panasiuk, AF | 1 |
Tarasenkova, TA | 1 |
Ntoso, KA | 1 |
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Yoshioka, A | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
An Open Label Extension Study of Brentuximab Vedotin Treatment in Active Diffuse Cutaneous Systemic Sclerosis (Diffuse Scleroderma)[NCT05149768] | Phase 2 | 11 participants (Anticipated) | Interventional | 2024-06-01 | Not yet recruiting | ||
The Effectiveness of ECP in Diffuse Cutaneous Systemic Sclerosis[NCT04986605] | Phase 2 | 15 participants (Anticipated) | Interventional | 2023-12-01 | Not yet recruiting | ||
A Pilot Study of Adcetris Treatment in Active Diffuse Cutaneous Systemic Sclerosis (Diffuse Scleroderma)[NCT03198689] | Phase 2 | 11 participants (Actual) | Interventional | 2019-05-07 | Completed | ||
An Observational, Long-term Follow-up Study of Eligible Individuals Declining To Participate in the Scleroderma Cyclophosphamide or Transplantation (SCOT) Study (SCSSc-02)[NCT00860548] | 19 participants (Actual) | Observational | 2005-06-30 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
46 reviews available for penicillamine and Sclerosis, Systemic
Article | Year |
---|---|
Assessment of kidney involvement in systemic sclerosis: From scleroderma renal crisis to subclinical renal vasculopathy.
Topics: Acute Kidney Injury; Antibodies, Antineutrophil Cytoplasmic; Humans; Kidney; Penicillamine; Peroxida | 2022 |
Systemic vasculitis during the course of systemic sclerosis: report of 12 cases and review of the literature.
Topics: Adrenal Cortex Hormones; Adult; Antibodies, Antineutrophil Cytoplasmic; Antirheumatic Agents; Biomar | 2013 |
[Efficacy of anti-thymocyte globulin and cyclosporin A combined therapy in aplastic anemia complicated with limited cutaneous systemic sclerosis].
Topics: Aged; Anemia, Aplastic; Antilymphocyte Serum; Cyclosporine; Female; Granulocyte Colony-Stimulating F | 2005 |
[Treatment of systemic sclerosis].
Topics: Cyclophosphamide; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Hematopoietic S | 2006 |
[Therapeutic management of systemic sclerosis].
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Anti-Inflam | 2006 |
Scleroderma: therapeutic options.
Topics: Alprostadil; Captopril; Colchicine; Griseofulvin; Humans; Immunosuppressive Agents; Nifedipine; Peni | 1984 |
[Treatment of systemic scleroderma].
Topics: Calcium Channel Blockers; Captopril; Clinical Trials as Topic; Colchicine; Factor XIII; Humans; Peni | 1984 |
[Hydrocortisone and cuprenil phonophoresis in the therapy of scleroderma].
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Drug Combinations; Drug Evaluation; Female | 1980 |
[Systemic sclerosis].
Topics: Adjuvants, Immunologic; Adult; Female; Humans; Male; Middle Aged; Penicillamine; Scleroderma, Locali | 1994 |
Outcome measurement in scleroderma clinical trials.
Topics: Clinical Trials as Topic; Dimethyl Sulfoxide; Female; Humans; Male; Penicillamine; Photopheresis; Pr | 1993 |
Outcome measurement in scleroderma clinical trials.
Topics: Clinical Trials as Topic; Dimethyl Sulfoxide; Female; Humans; Male; Penicillamine; Photopheresis; Pr | 1993 |
Outcome measurement in scleroderma clinical trials.
Topics: Clinical Trials as Topic; Dimethyl Sulfoxide; Female; Humans; Male; Penicillamine; Photopheresis; Pr | 1993 |
Outcome measurement in scleroderma clinical trials.
Topics: Clinical Trials as Topic; Dimethyl Sulfoxide; Female; Humans; Male; Penicillamine; Photopheresis; Pr | 1993 |
Outcome measurement in scleroderma clinical trials.
Topics: Clinical Trials as Topic; Dimethyl Sulfoxide; Female; Humans; Male; Penicillamine; Photopheresis; Pr | 1993 |
Outcome measurement in scleroderma clinical trials.
Topics: Clinical Trials as Topic; Dimethyl Sulfoxide; Female; Humans; Male; Penicillamine; Photopheresis; Pr | 1993 |
Outcome measurement in scleroderma clinical trials.
Topics: Clinical Trials as Topic; Dimethyl Sulfoxide; Female; Humans; Male; Penicillamine; Photopheresis; Pr | 1993 |
Outcome measurement in scleroderma clinical trials.
Topics: Clinical Trials as Topic; Dimethyl Sulfoxide; Female; Humans; Male; Penicillamine; Photopheresis; Pr | 1993 |
Outcome measurement in scleroderma clinical trials.
Topics: Clinical Trials as Topic; Dimethyl Sulfoxide; Female; Humans; Male; Penicillamine; Photopheresis; Pr | 1993 |
Activation of dermal connective tissue in scleroderma.
Topics: Cell Adhesion Molecules; Chemotaxis, Leukocyte; Collagen; Connective Tissue; Cyclosporine; Cytokines | 1993 |
Bronchiolitis obliterans in a patient with localized scleroderma treated with D-penicillamine.
Topics: Antirheumatic Agents; Bronchiolitis Obliterans; Humans; Lung Transplantation; Male; Middle Aged; Pen | 1996 |
Treatment of systemic sclerosis.
Topics: Antirheumatic Agents; Calcinosis; Clinical Trials as Topic; Gastrointestinal Diseases; Heart Disease | 1996 |
D-penicillamine-induced crescentic glomerulonephritis and antimyeloperoxidase antibodies in a patient with scleroderma. Case report and review of the literature.
Topics: Aged; Autoantibodies; Biopsy; Female; Glomerulonephritis; Humans; Kidney Glomerulus; Microscopy, Ele | 1997 |
A case study and national database report of progressive systemic sclerosis and associated conditions.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Cause of Deat | 1998 |
D-penicillamine-induced crescentic glomerulonephritis in a patient with scleroderma.
Topics: Acute Kidney Injury; Aged; Glomerulonephritis; Humans; Male; Penicillamine; Scleroderma, Systemic | 2000 |
[Systemic scleroderma].
Topics: Diagnosis, Differential; Humans; Penicillamine; Peripheral Nervous System Diseases; Prognosis; Scler | 2000 |
Clinical trials for the treatment of systemic sclerosis/scleroderma.
Topics: Antirheumatic Agents; Clinical Trials as Topic; Cyclophosphamide; Female; Humans; Male; Penicillamin | 1999 |
Penicillamine in the treatment of systemic sclerosis.
Topics: Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Hu | 1999 |
[Scleroderma].
Topics: Antibodies, Antinuclear; Autoimmunity; Collagen; Cytokines; Diagnosis, Differential; Humans; Penicil | 2000 |
[Scleroderma].
Topics: Autoantibodies; Cytokines; Humans; Immunosuppressive Agents; Intercellular Adhesion Molecule-1; Lymp | 2000 |
Combination therapies for systemic sclerosis.
Topics: Antirheumatic Agents; Drug Therapy, Combination; Humans; Immunosuppressive Agents; Penicillamine; Sc | 2001 |
[Systemic sclerosis].
Topics: Alprostadil; Collagen; Cytokines; Diagnosis, Differential; Fibrillins; Humans; Microfilament Protein | 2001 |
Juvenile systemic scleroderma.
Topics: Adolescent; Age Factors; Child; Child, Preschool; Female; Hematopoietic Stem Cell Transplantation; H | 2001 |
D-penicillamine in systemic sclerosis? Yes!
Topics: Antirheumatic Agents; Collagen; Dose-Response Relationship, Drug; Double-Blind Method; Fibrosis; Hum | 2001 |
D-penicillamine is not an effective treatment in systemic sclerosis.
Topics: Antirheumatic Agents; Double-Blind Method; Humans; Penicillamine; Randomized Controlled Trials as To | 2001 |
Treating systemic sclerosis in 2001.
Topics: Antineoplastic Agents; Antirheumatic Agents; Combined Modality Therapy; Drug Therapy, Combination; F | 2001 |
Current treatment options in systemic Sclerosis (Scleroderma).
Topics: Antirheumatic Agents; Gastrointestinal Diseases; Hematopoietic Stem Cell Transplantation; Humans; Hy | 2002 |
[Indications and limits of long-term therapy with immunosuppressive (and cytostatic) agents in various chronic skin diseases].
Topics: Arthritis, Reactive; Azathioprine; Chronic Disease; Cyclophosphamide; Dermatomyositis; Humans; Immun | 1977 |
Penicillamine types in the sclerodermas.
Topics: Humans; Penicillamine; Raynaud Disease; Scleroderma, Systemic | 1977 |
D-penicillamine in the treatment of rheumatoid arthritis and progressive systemic sclerosis.
Topics: Animals; Arthritis, Rheumatoid; Chelating Agents; Collagen; Copper; Humans; Leukopenia; Nephrotic Sy | 1976 |
[Effects and adverse effects of D-penicillamine].
Topics: Bone Marrow Diseases; Chronic Disease; Cystinuria; Erythropoiesis; Hepatitis; Hepatolenticular Degen | 1975 |
Treatment of systemic sclerosis.
Topics: Cyclosporine; Humans; Methotrexate; Penicillamine; Photochemotherapy; Raynaud Disease; Scleroderma, | 1992 |
Drug-induced scleroderma.
Topics: Amphetamine; Bleomycin; Cocaine; Diethylpropion; Drug-Related Side Effects and Adverse Reactions; Hu | 1991 |
Treatment of systemic sclerosis.
Topics: Colchicine; Humans; Immunosuppressive Agents; Penicillamine; Scleroderma, Systemic | 1991 |
Photopheresis in the treatment of autoimmune disease: experience with pemphigus vulgaris and systemic sclerosis.
Topics: Autoimmune Diseases; Humans; Leukapheresis; Pemphigus; Penicillamine; PUVA Therapy; Scleroderma, Sys | 1991 |
Current topics in the diagnosis and treatment of scleroderma.
Topics: Adult; Female; Humans; Nifedipine; Penicillamine; Scleroderma, Systemic | 1991 |
D-penicillamine.
Topics: Arthritis, Juvenile; Arthritis, Rheumatoid; Drug Prescriptions; Humans; Penicillamine; Rheumatic Dis | 1990 |
The current treatment of scleroderma.
Topics: Angiotensin-Converting Enzyme Inhibitors; Female; Humans; Male; Penicillamine; Scleroderma, Systemic | 1989 |
Treatment of systemic sclerosis.
Topics: Humans; Immunosuppressive Agents; Penicillamine; Scleroderma, Systemic | 1989 |
[Scleroderma and thyroid diseases].
Topics: Aged; Confidence Intervals; Female; Humans; Incidence; Male; Middle Aged; Penicillamine; Prospective | 1989 |
D-penicillamine: chemistry and clinical use in rheumatic disease.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Drug Eruptions; Gold Sodium Thiomalate; Hematologic Dise | 1986 |
[D-penicillamine and collagen].
Topics: Aminopropionitrile; Arthritis, Rheumatoid; Autoantibodies; Bronchi; Cicatrix; Collagen; Collagen Dis | 1986 |
[Therapeutic use of d-penicillamine].
Topics: Arthritis, Rheumatoid; Basement Membrane; Collagen; Copper; Cystinuria; Hematopoiesis; Hepatolenticu | 1972 |
Copper and taste sensitivity.
Topics: Arthritis, Rheumatoid; Ceruloplasmin; Copper; Cystinuria; Depression, Chemical; Hepatolenticular Deg | 1968 |
[Penicillamine in the light of current clinical research].
Topics: Antidotes; Arthritis; Arthritis, Rheumatoid; Chronic Disease; Collagen; Copper; Depression, Chemical | 1970 |
21 trials available for penicillamine and Sclerosis, Systemic
Article | Year |
---|---|
Course of the modified Rodnan skin thickness score in systemic sclerosis clinical trials: analysis of three large multicenter, double-blind, randomized controlled trials.
Topics: Adult; Age of Onset; Animals; Antirheumatic Agents; Cattle; Collagen Type I; Disease Progression; Fe | 2009 |
Predictors and outcomes of scleroderma renal crisis: the high-dose versus low-dose D-penicillamine in early diffuse systemic sclerosis trial.
Topics: Adult; Female; Humans; Kidney Diseases; Male; Middle Aged; Penicillamine; Retrospective Studies; Scl | 2002 |
Effect of D-penicillamine on pulmonary fibrosis in patients with systemic sclerosis.
Topics: Adult; Antirheumatic Agents; Female; Humans; Male; Middle Aged; Penicillamine; Pulmonary Fibrosis; R | 2003 |
Minocycline is not effective in systemic sclerosis: results of an open-label multicenter trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Dose-Response Relations | 2004 |
High-dose versus low-dose D-penicillamine in early diffuse systemic sclerosis trial: lessons learned.
Topics: Adult; Antirheumatic Agents; Disability Evaluation; Dose-Response Relationship, Drug; Female; Follow | 2004 |
65Zinc absorption in untreated and D-penicillamine-treated patients with generalized scleroderma: determination by whole-body counting technique.
Topics: Administration, Oral; Humans; Penicillamine; Scleroderma, Systemic; Whole-Body Counting; Zinc Radioi | 1982 |
Progressive systemic sclerosis.
Topics: Adrenal Cortex Hormones; Clinical Trials as Topic; Colchicine; Drug Evaluation; Follow-Up Studies; H | 1983 |
[Treatment of systemic scleroderma].
Topics: Calcium Channel Blockers; Captopril; Clinical Trials as Topic; Colchicine; Factor XIII; Humans; Peni | 1984 |
Therapy for severe interstitial lung disease in systemic sclerosis. A retrospective study.
Topics: Adult; Bronchoalveolar Lavage Fluid; Cell Count; Cyclophosphamide; Female; Humans; Immunosuppressive | 1994 |
Photopheresis for scleroderma? Let's abandon the innuendos and get to the data.
Topics: Blood Component Removal; Costs and Cost Analysis; Extracorporeal Circulation; Humans; Penicillamine; | 1993 |
[A prospective study of plasma exchange in the treatment of diffuse scleroderma].
Topics: Adult; Antirheumatic Agents; Combined Modality Therapy; Female; Humans; Male; Penicillamine; Plasma | 1995 |
High-dose versus low-dose D-penicillamine in early diffuse systemic sclerosis: analysis of a two-year, double-blind, randomized, controlled clinical trial.
Topics: Adult; Antirheumatic Agents; Creatine Kinase; Dose-Response Relationship, Drug; Double-Blind Method; | 1999 |
The Disability Index of the Health Assessment Questionnaire is a predictor and correlate of outcome in the high-dose versus low-dose penicillamine in systemic sclerosis trial.
Topics: Disability Evaluation; Dose-Response Relationship, Drug; Health Status Indicators; Humans; Logistic | 2001 |
Long-term therapy with plasma exchange in systemic sclerosis: effects on laboratory markers reflecting disease activity.
Topics: Adult; Aged; Antibody Specificity; Autoantibodies; Autoimmune Diseases; Biomarkers; Combined Modalit | 2001 |
Treatment of generalized scleroderma with inhibitors of connective tissue formation.
Topics: Adult; Age Factors; Clinical Trials as Topic; Connective Tissue; Depression, Chemical; Dextrothyroxi | 1975 |
The use of penicillamine in the treatment of rheumatoid arthritis and scleroderma.
Topics: Adult; Arthritis, Rheumatoid; Child; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; | 1979 |
Long-term evaluation of penicillamine or cyclofenil in systemic sclerosis. Results from a two-year randomized study.
Topics: Adult; Aged; Cyclofenil; Electrocardiography; Esophagus; Exercise; Female; Heart; Humans; Immune Sys | 1992 |
Treatment of systemic sclerosis with extracorporeal photochemotherapy. Results of a multicenter trial.
Topics: Adult; Aged; Combined Modality Therapy; Female; Humans; Immunotherapy; Leukapheresis; Leukocytes; Ma | 1992 |
A 15-year prospective study of treatment of rapidly progressive systemic sclerosis with D-penicillamine [see comment].
Topics: Adolescent; Adult; Aged; Female; Humans; Male; Middle Aged; Penicillamine; Retrospective Studies; Sc | 1991 |
D-penicillamine treatment of lung involvement in patients with systemic sclerosis (scleroderma).
Topics: Clinical Trials as Topic; Humans; Penicillamine; Pulmonary Fibrosis; Scleroderma, Systemic; Time Fac | 1987 |
[Effectiveness of long-term use of dimethyl sulfoxide in the complex treatment of patients with systemic scleroderma].
Topics: Adolescent; Adult; Clinical Trials as Topic; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; D | 1985 |
171 other studies available for penicillamine and Sclerosis, Systemic
Article | Year |
---|---|
Generalized scleroderma-like induration associated with D-penicillamine elastosis perforans serpiginosa in Wilson's disease.
Topics: Hepatolenticular Degeneration; Humans; Penicillamine; Scleroderma, Localized; Scleroderma, Systemic; | 2023 |
Limited systemic sclerosis initially presenting with mesenteric panniculitis.
Topics: Antirheumatic Agents; Biopsy; Diagnosis, Differential; Fat Necrosis; Female; Follow-Up Studies; Huma | 2014 |
Asymptomatic annular plaques on the neck.
Topics: Adult; Antirheumatic Agents; Biopsy; Drug-Related Side Effects and Adverse Reactions; Female; Humans | 2014 |
Annular keratotic papules on the extremities.
Topics: Adult; Antirheumatic Agents; Elastic Tissue; Extremities; Female; Humans; Penicillamine; Scleroderma | 2015 |
Diagnosis and treatment of scleroderma.
Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Female; Humans; Immunosuppressive Agents; Male; Penic | 2008 |
Ankylosing spondylitis and systemic sclerosis: a rare combination.
Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Drug Therapy, Combination; Histocompatibility | 2009 |
[Effect of Wenyang Huazhuo Tongluo recipe contained serum on proliferation and cell cycle of systemic sclerosis skin fibroblasts].
Topics: Adult; Cell Cycle; Cell Proliferation; Cells, Cultured; Drug Combinations; Drugs, Chinese Herbal; Fe | 2009 |
Anti-MuSK- and anti-AChR-positive myasthenia gravis induced by d-penicillamine.
Topics: Aged; Antirheumatic Agents; Autoantibodies; Autoantigens; Female; Humans; Myasthenia Gravis; Penicil | 2012 |
Clinical trials for pediatric scleroderma.
Topics: Antirheumatic Agents; Child; Clinical Trials as Topic; Cyclophosphamide; Humans; Methotrexate; Penic | 2002 |
Predictors and outcomes of scleroderma renal crisis: data from the high-dose versus low-dose D-penicillamine in early diffuse systemic sclerosis trial.
Topics: Humans; Kidney Diseases; Penicillamine; Randomized Controlled Trials as Topic; Scleroderma, Systemic | 2002 |
D-penicillamine induced polymyositis and morphea in a woman with Hashimoto thyroiditis.
Topics: Aged; Antirheumatic Agents; Female; Humans; Penicillamine; Polymyositis; Scleroderma, Localized; Scl | 2002 |
Goodpasture-like syndrome induced by D-penicillamine in a patient with systemic sclerosis: report and review of the literature.
Topics: Aged; Anti-Glomerular Basement Membrane Disease; Antirheumatic Agents; Fatal Outcome; Glomerulonephr | 2003 |
Epidermolysis bullosa acquisita-like reaction associated with penicillamine therapy for sclerodermatous graft-versus-host disease.
Topics: Bone Marrow Transplantation; Cyclosporine; Epidermolysis Bullosa Acquisita; Graft vs Host Disease; H | 2003 |
[Obliterating bronchiolitis induced by D-penicillamine in the female patient with systemic scleroderma].
Topics: Adult; Beclomethasone; Bronchiolitis Obliterans; Cyclophosphamide; Female; Humans; Methylprednisolon | 2004 |
[Minimal changes nephrotic syndrome associated to penicillamine treatment].
Topics: Adult; Arthritis, Rheumatoid; Autoimmune Diseases; Female; Humans; Immunosuppressive Agents; Middle | 2004 |
Improvement of skin sclerosis after occurrence of anticentromere antibody in a patient with diffuse cutaneous systemic sclerosis.
Topics: Administration, Oral; Adult; Antibodies, Antineutrophil Cytoplasmic; Antirheumatic Agents; Centromer | 2004 |
D-penicillamine-induced pemphigus vulgaris in a patient with scleroderma-rheumatoid arthritis overlap syndrome.
Topics: Arthritis, Rheumatoid; Female; Follow-Up Studies; Humans; Middle Aged; Pemphigus; Penicillamine; Ris | 2004 |
Pulmonary involvement in systemic sclerosis due to therapy and as a complication.
Topics: Antirheumatic Agents; Bronchiectasis; Bronchiolitis; Female; Follow-Up Studies; Humans; Hypertension | 2005 |
A case of nodular scleroderma.
Topics: Adult; Biopsy, Needle; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Immunohistochem | 2005 |
[Systemic sclerosis--a challenge in rheumatology].
Topics: Antibodies, Antinuclear; Gastrointestinal Diseases; Humans; Hypertension, Pulmonary; Immunosuppressi | 2006 |
Collagenous colitis in a patient with systemic sclerosis: a rare entity.
Topics: Abdomen; Aged; Autoimmune Diseases; Colitis, Collagenous; Comorbidity; Diarrhea; Female; Humans; Lop | 2007 |
Eosinophilic fasciitis (Shulman syndrome) in association with morphoea and systemic sclerosis.
Topics: Eosinophils; Fascia; Humans; Inflammation; Male; Middle Aged; Penicillamine; Scleroderma, Localized; | 1980 |
[D-Penicillamine effect on collagen synthesis and structural maintenance Red Sirius staining with polarized-light examination. The value of this staining in cases of collagen diseases (author's transl)].
Topics: Adult; Collagen; Connective Tissue; Humans; Male; Microscopy, Polarization; Penicillamine; Scleroder | 1982 |
[Cholestatic jaundice induced by D-penicillamine and oral steroid contraceptive in progressive systemic sclerosis (author's transl)].
Topics: Adult; Alanine Transaminase; Bilirubin; Chlormadinone Acetate; Cholestasis, Intrahepatic; Contracept | 1982 |
Does long-term treatment with D-penicillamine alter calcium and phosphorus metabolism in patients with systemic sclerosis?
Topics: Adult; Aged; Calcium; Female; Humans; Male; Middle Aged; Penicillamine; Phosphorus; Scleroderma, Sys | 1983 |
Zinc and zinc-dependent enzymes in penicillamine-treated patients with generalized scleroderma.
Topics: Adult; Aged; Alkaline Phosphatase; Carbonic Anhydrases; Erythrocytes; Female; Granulocytes; Humans; | 1984 |
Systemic sclerosis.
Topics: Adult; Captopril; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Penicillamine; Sclerod | 1984 |
Changes in the growth and metabolism of cells cultured from normal, sclerotic and rheumatoid connective tissue brought about by D-penicillamine and by sodium salicylate.
Topics: Adult; Arthritis, Rheumatoid; Cell Division; Cells, Cultured; Fibroblasts; Glycosaminoglycans; Human | 1980 |
[Collagen metabolites in the urine in patients with generalized scleroderma].
Topics: Adult; Aged; Amino Acids; Collagen; Female; Glutamine; Humans; Male; Middle Aged; Penicillamine; Scl | 1984 |
[Prognosis and treatment of scleroderma].
Topics: Adrenal Cortex Hormones; Autoantibodies; Colchicine; Humans; Immunosuppressive Agents; Penicillamine | 1984 |
[Myasthenia gravis induced by D-penicillamine in a patient with progressive systemic sclerosis].
Topics: Adult; Autoimmune Diseases; Female; Humans; Myasthenia Gravis; Neuromuscular Junction; Penicillamine | 1984 |
Antibodies to cellular antigens in Greek patients with autoimmune rheumatic diseases: anti-Ro(SSA) antibody a possible marker of penicillamine-D intolerance.
Topics: Adult; Aged; Antigens; Arthritis, Rheumatoid; Autoantibodies; Autoantigens; Autoimmune Diseases; Fem | 1984 |
[Morphology and pathogenesis of penicillamine-induced nephropathy].
Topics: Adult; Alveolitis, Extrinsic Allergic; Arthritis, Rheumatoid; Biopsy; Female; Glomerulonephritis; Hu | 1983 |
The gastrointestinal manifestations of scleroderma: pathogenesis and management.
Topics: Action Potentials; Diagnosis, Differential; Digestive System; Gastrointestinal Diseases; Gastrointes | 1980 |
Penicillamine and progressive systemic sclerosis.
Topics: Drug Evaluation; Humans; Penicillamine; Prospective Studies; Scleroderma, Systemic | 1983 |
D-penicillamine treatment of progressive systemic sclerosis (scleroderma): a comparison of clinical and in vitro effects.
Topics: Adult; Aged; Cells, Cultured; Female; Fibroblasts; Glycosaminoglycans; Humans; In Vitro Techniques; | 1983 |
Historical perspectives on penicillamine.
Topics: Animals; Chelating Agents; Chemical Phenomena; Chemistry; Hepatitis; Humans; Immunity; Lathyrism; Li | 1980 |
[D-penicillamine in the treatment of progressive systemic sclerosis].
Topics: Adolescent; Adult; Female; Follow-Up Studies; Humans; Middle Aged; Penicillamine; Scleroderma, Syste | 1980 |
Hidden anti-nuclear antibodies in rheumatic diseases.
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Collagen Diseases; Fluorescent Antibody Technique; H | 1980 |
Successful treatment of far-advanced progressive systemic sclerosis by D-penicillamine.
Topics: Adolescent; Adult; Blood Volume; Collagen; Colonic Diseases; Electrocardiography; Female; Humans; In | 1982 |
[Experience using d-penicillamine in systemic scleroderma].
Topics: Adult; Biopsy; Drug Evaluation; Female; Humans; Male; Middle Aged; Penicillamine; Scleroderma, Syste | 1982 |
Treatment of generalized scleroderma with inhibitors of collagen synthesis.
Topics: Catechin; Chlorpromazine; Collagen; Dextrothyroxine; Glutamine; Humans; Hydralazine; Levodopa; Penic | 1982 |
D-Penicillamine therapy in progressive systemic sclerosis (scleroderma): a retrospective analysis.
Topics: Biopsy; Contracture; Female; Humans; Male; Middle Aged; Penicillamine; Retrospective Studies; Sclero | 1982 |
[D-penicillamine-induced lipoid nephrosis in a patient with scleroderma].
Topics: Female; Humans; Kidney; Middle Aged; Nephrosis, Lipoid; Penicillamine; Scleroderma, Systemic | 1982 |
[Progressive systemic sclerosis with gastrointestinal manifestations].
Topics: Adult; Gastrointestinal Diseases; Glutamine; Humans; Male; Penicillamine; Scleroderma, Systemic | 1982 |
[Pregnancy and rheumatic disease (author's transl)].
Topics: Arthritis, Rheumatoid; Female; Gold; Humans; Penicillamine; Pregnancy; Pregnancy Complications; Scle | 1981 |
[Microcirculatory disorders in systemic scleroderma treated with d-penicillamine].
Topics: Adult; Capillary Permeability; Female; Humans; Male; Microcirculation; Muscles; Penicillamine; Scler | 1981 |
Penicillamine-induced myasthenia gravis in progressive systemic sclerosis.
Topics: Adult; Female; Humans; Myasthenia Gravis; Penicillamine; Scleroderma, Systemic | 1980 |
[Nephropathy in a patient with systemic scleroderma treated with D-penicillamine].
Topics: Humans; Male; Middle Aged; Nephrotic Syndrome; Penicillamine; Scleroderma, Systemic | 1980 |
[Scleroderma in the child. Treatment with colchicine].
Topics: Child; Colchicine; Female; Humans; Penicillamine; Scleroderma, Systemic | 1980 |
Nodular scleroderma: focally increased tenascin expression differing from that in the surrounding scleroderma skin.
Topics: Adult; Biopsy; Cell Adhesion Molecules, Neuronal; Diagnosis, Differential; Extracellular Matrix Prot | 1995 |
[Multifocal idiopathic fibrosis].
Topics: Adult; Diagnosis, Differential; Drug Therapy, Combination; Humans; Male; Penicillamine; Prednisolone | 1994 |
The use of serologic markers for collagen synthesis and degradation in systemic sclerosis.
Topics: Biomarkers; Blister; Collagen; Collagen Type I; Cyclophosphamide; Cyclosporine; Exudates and Transud | 1995 |
Breast gigantism due to D-penicillamine.
Topics: Breast Diseases; Female; Gigantism; Humans; Middle Aged; Penicillamine; Scleroderma, Systemic | 1994 |
Unilateral ptosis as an initial manifestation of D-penicillamine induced myasthenia gravis.
Topics: Adult; Arthritis, Rheumatoid; Blepharoptosis; Female; Humans; Myasthenia Gravis; Penicillamine; Scle | 1993 |
Toward rational treatment of scleroderma.
Topics: Humans; Interferon-gamma; Penicillamine; Scleroderma, Systemic | 1993 |
Therapy for childhood rheumatic diseases. Have we been doing enough?
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Juvenile; Child; Child, Pr | 1993 |
Chromosome abnormalities in peripheral lymphocytes from patients with progressive systemic sclerosis.
Topics: Adult; Aged; Asian People; Base Sequence; Cells, Cultured; Chromosome Aberrations; Chromosome Disord | 1993 |
Childhood-onset scleroderma: is it different from adult-onset disease.
Topics: Adolescent; Adult; Age of Onset; Anti-Inflammatory Agents; Antirheumatic Agents; Autoantibodies; Chi | 1996 |
Cystic lung disease in systemic sclerosis: a case report with high resolution computed tomography findings.
Topics: Adult; Antirheumatic Agents; Cysts; Female; Humans; Lung Diseases; Nifedipine; Penicillamine; Pulmon | 1996 |
Pulmonary hypertension in systemic sclerosis: an analysis of 17 patients.
Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Cohort Studies; Demography; Dyspnea; Female; | 1996 |
Intestinal pseudo-obstruction as an initial presentation of systemic sclerosis in two children.
Topics: Adolescent; Anti-Inflammatory Agents; Antirheumatic Agents; Child, Preschool; Dermatologic Agents; F | 1997 |
Organizing diffuse alveolar damage associated with progressive systemic sclerosis.
Topics: Aged; Antirheumatic Agents; Biopsy; Female; Humans; Middle Aged; Pancytopenia; Penicillamine; Pulmon | 1997 |
Transient acantholytic dermatosis (Grover's disease) in a patient with progressive systemic sclerosis treated with D-penicillamine.
Topics: Acantholysis; Antirheumatic Agents; Chelating Agents; Female; Humans; Middle Aged; Penicillamine; Sc | 1997 |
Scleroderma, D-penicillamine treatment, and progressive renal failure associated with positive antimyeloperoxidase antineutrophil cytoplasmic antibodies.
Topics: Antibodies, Antineutrophil Cytoplasmic; Autoantibodies; Female; Glomerulonephritis; Humans; Middle A | 1997 |
[A patient with systemic scleroderma showing improvement during long-term hemodialysis after renal crisis].
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antirheumatic Agents; Humans; Kidney Diseases; Male; | 1997 |
Case-control study of corticosteroids and other drugs that either precipitate or protect from the development of scleroderma renal crisis.
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroid | 1998 |
Postural changes, dysphagia, and systemic sclerosis.
Topics: Antirheumatic Agents; Deglutition Disorders; Diagnosis, Differential; Histocompatibility Testing; Hu | 1998 |
[A case of myasthenia gravis caused by D-penicillamine therapy].
Topics: Adult; Antirheumatic Agents; Female; Humans; Myasthenia Gravis; Penicillamine; Plasma Exchange; Scle | 1998 |
[Extracapillary glomerulonephritis with anti-myeloperoxidase antibodies in 2 patients with systemic scleroderma treated with penicillamine D].
Topics: Aged; Antibodies, Antineutrophil Cytoplasmic; Autoimmune Diseases; Female; Glomerulonephritis; Human | 1999 |
[Extra-capillary glomerulonephritis induced by D-penicillamine therapy].
Topics: Glomerulonephritis; Humans; Male; Middle Aged; Penicillamine; Scleroderma, Systemic | 1999 |
Correlates of the disability index of the health assessment questionnaire: a measure of functional impairment in systemic sclerosis.
Topics: Adolescent; Adult; Aged; Disability Evaluation; Female; Health Surveys; Humans; Logistic Models; Mal | 1999 |
In vitro inhibition of hematopoiesis in a patient with systemic sclerosis treated with D-penicillamine.
Topics: Aged; Anemia; Antirheumatic Agents; Colony-Forming Units Assay; Female; Hematopoiesis; Humans; Penic | 1999 |
[D-penicillamine: an outdated cure for systemic scleroderma?].
Topics: Antirheumatic Agents; Humans; Penicillamine; Prognosis; Scleroderma, Systemic; Skin Diseases; Surviv | 1999 |
Pemphigus vulgaris induced by D-penicillamine therapy in a patient with systemic sclerosis.
Topics: Aged; Antirheumatic Agents; Disease Progression; Female; Humans; Pemphigus; Penicillamine; Scleroder | 2000 |
Skin thickness score as a predictor and correlate of outcome in systemic sclerosis: high-dose versus low-dose penicillamine trial.
Topics: Adult; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; Linear Models; Lo | 2000 |
[Two cases of successfully treated multifocal fibrosis].
Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Diagnosis, Differential; Drug Therapy, Combin | 2002 |
Letter: Marrow aplasia and penicillamine.
Topics: Anemia, Aplastic; Arthritis, Rheumatoid; Bone Marrow; Female; Humans; Middle Aged; Penicillamine; Sc | 1976 |
Treatment of generalized scleroderma: updated results.
Topics: Chlorpromazine; Collagen; Drug Evaluation; Glutamine; Glycosaminoglycans; Humans; Hydralazine; Levod | 1979 |
Penicillamine therapy in systemic sclerosis.
Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Penicillamine; Scleroderma, Systemic | 1977 |
Treatment of scleroderma heart by D-penicillamine.
Topics: Adult; Cardiomegaly; Cardiomyopathies; Exercise Test; Female; Heart Failure; Humans; Penicillamine; | 1976 |
Scleroderma in childhood.
Topics: Adolescent; Central Nervous System Diseases; Child; Child, Preschool; Female; Humans; Immunosuppress | 1977 |
Connective tissue changes in systemic sclerosis and the use of D-penicillamine.
Topics: Collagen; Connective Tissue; Humans; Penicillamine; Scleroderma, Systemic | 1979 |
[Drug therapy of various collagen diseases based on connective tissue metabolism--with special reference to systemic scleroderma].
Topics: Adult; Connective Tissue; Drug Evaluation; Female; Humans; Male; Middle Aged; Penicillamine; Plant E | 1977 |
Scleroderma with massive regional lymphadenopathy.
Topics: Child, Preschool; Humans; Lymphatic Diseases; Male; Penicillamine; Scleroderma, Systemic | 1979 |
[Treatment of scleroderma and dermatomyositis in childhood].
Topics: Adolescent; Age Factors; Aluminum Hydroxide; Anabolic Agents; Child; Cyclophosphamide; Dermatomyosit | 1978 |
Taste dysfunction and changes in zinc and copper metabolism during penicillamine therapy for generalized scleroderma.
Topics: Adult; Aged; Arthritis, Rheumatoid; Copper; Female; Humans; Male; Metabolic Diseases; Middle Aged; P | 1978 |
Scleroderma (progressive systemic sclerosis, PSS); pathophysiological, clinical and pharmacological aspects of the syndrome.
Topics: Cyclofenil; Humans; Male; Middle Aged; Penicillamine; Scleroderma, Systemic; Skin | 1978 |
(D)-penicillamine treatment in systemic sclerosis (scleroderma). Effect on nutritional capillary circulation.
Topics: Adult; Aged; Capillaries; Capillary Permeability; Female; Humans; Male; Middle Aged; Penicillamine; | 1977 |
[Effect of D-penicillamine in scleroderma complicating phenylketonuria].
Topics: Child, Preschool; Humans; Male; Penicillamine; Phenylketonurias; Scleroderma, Systemic | 1976 |
[Treatment of interstitial pulmonary fibrosis with D-penicillamine in progressive scleroderma: a long-term study (author's transl)].
Topics: Aged; Drug Evaluation; Female; Follow-Up Studies; Humans; Immunosuppressive Agents; Male; Middle Age | 1976 |
Scleroderma in childhood.
Topics: Adolescent; Age Factors; Arthritis, Juvenile; Bone Diseases; Child; Chlorambucil; Diagnosis, Differe | 1976 |
[Clinical and prognostic significance of antinuclear factors during D-penicillamine treatment (author's transl)].
Topics: Adult; Antibodies, Antinuclear; Arthritis, Rheumatoid; Humans; Kidney Diseases; Male; Middle Aged; P | 1975 |
[Biosynthesis of collagen and mode of action of D-penicillamine (author's transl)].
Topics: Amino Acids; Animals; Aorta; Binding Sites; Cartilage; Collagen; Connective Tissue; Hepatitis; Human | 1975 |
Cutaneous extensibility in health and disease.
Topics: Acromegaly; Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Collagen; Cutis Laxa; Ehlers-Da | 1975 |
Renal involvement in progressive systemic sclerosis.
Topics: Acute Kidney Injury; Adult; Blood Pressure; Female; Humans; Penicillamine; Peritoneal Dialysis; Scle | 1975 |
[Treatment of generalized scleroderma with connective tissue inhibitors].
Topics: Adrenal Cortex Hormones; Adult; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydral | 1976 |
[Proteinuria in immunopathological diseases during long-term penicillamine therapy (author's transl)].
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Humans; Penicillamine; Proteinuria; Scleroderma, Systemi | 1976 |
Nodular scleroderma in systemic sclerosis under D-penicillamine therapy.
Topics: Adult; Female; Humans; Penicillamine; Scleroderma, Systemic; Skin | 1992 |
Photochemotherapy in systemic sclerosis. The stage is set.
Topics: Humans; Leukocytes; Methoxsalen; Penicillamine; Photochemotherapy; Scleroderma, Systemic; Ultraviole | 1992 |
Serum levels of aminoterminal type III procollagen peptide and hyaluronan predict mortality in systemic sclerosis.
Topics: Cyclofenil; Female; Humans; Hyaluronic Acid; Male; Penicillamine; Peptide Fragments; Procollagen; Pr | 1992 |
[Therapeutic possibilities in systemic scleroderma].
Topics: Antibodies, Antinuclear; Autoantibodies; Azathioprine; Combined Modality Therapy; Dose-Response Rela | 1992 |
Progressive systemic sclerosis complicated with immune thrombocytopenia during D-penicillamine therapy.
Topics: Blood Platelets; Female; Humans; Immunoglobulin G; Middle Aged; Penicillamine; Scleroderma, Systemic | 1992 |
Why everything (or nothing) seems to work in the treatment of scleroderma.
Topics: Humans; Penicillamine; Scleroderma, Systemic | 1992 |
Vesicular lesions in a woman with progressive systemic sclerosis. Penicillamine-induced intradermal vesicles: an example of human lathyrism.
Topics: Female; Humans; Lathyrism; Middle Aged; Penicillamine; Scleroderma, Systemic; Skin; Skin Diseases, V | 1992 |
Palindromic morphea: multiple recurrence of morphea lesions in a case of systemic sclerosis.
Topics: Female; Humans; Middle Aged; Penicillamine; Prednisolone; Recurrence; Scleroderma, Localized; Sclero | 1992 |
Spontaneous and clastogen induced chromosomal breakage in scleroderma.
Topics: 4-Nitroquinoline-1-oxide; Adult; Aged; Bleomycin; Cells, Cultured; Chromosome Aberrations; Chromosom | 1991 |
D-penicillamine treatment in systemic sclerosis.
Topics: Humans; Penicillamine; Scleroderma, Systemic | 1991 |
Immunological alterations during photopheresis and D-penicillamine treatment of systemic sclerosis.
Topics: Female; Humans; Leukapheresis; Male; Penicillamine; PUVA Therapy; Scleroderma, Systemic; T-Lymphocyt | 1991 |
Polymyositis due to D-penicillamine in a patient with systemic sclerosis.
Topics: Female; Humans; Middle Aged; Myositis; Penicillamine; Scleroderma, Systemic | 1991 |
Penicillamine in systemic sclerosis: a reappraisal.
Topics: Adult; Female; Humans; Male; Middle Aged; Penicillamine; Scleroderma, Localized; Scleroderma, System | 1990 |
[Fever caused by penicillin. Description of a clinical case].
Topics: Female; Fever; Humans; Middle Aged; Penicillamine; Scleroderma, Systemic | 1990 |
Lupus erythematosus-like eruption due to D-penicillamine in progressive systemic sclerosis.
Topics: Drug Eruptions; Female; Humans; Lupus Erythematosus, Cutaneous; Middle Aged; Penicillamine; Sclerode | 1990 |
The progress of oesophageal involvement in progressive systemic sclerosis during D-penicillamine treatment.
Topics: Esophagitis; Esophagus; Female; Gastroesophageal Reflux; Humans; Male; Penicillamine; Peristalsis; P | 1989 |
[Analysis of the distribution of class I HLA-antigens in patients with systemic scleroderma with regard to features of the clinical course of the disease and therapy with D-penicillamine].
Topics: Adolescent; Adult; Aged; Female; Gene Frequency; HLA-A Antigens; HLA-B Antigens; HLA-C Antigens; Hum | 1989 |
The toxicity of D-penicillamine in systemic sclerosis.
Topics: Arthritis, Rheumatoid; Digestive System Diseases; Dose-Response Relationship, Drug; Drug Eruptions; | 1986 |
[Effect of penicillin and D-penicillamine on beta-galactosidase activity in patients with progressive scleroderma].
Topics: beta-Galactosidase; Dose-Response Relationship, Drug; Galactosidases; Humans; Liver; Penicillamine; | 1988 |
[Epidemiological study of systemic scleroderma in Tokyo based on application forms for financial aid for patients with intractable diseases].
Topics: Adrenal Cortex Hormones; Adult; Age Factors; Aged; Female; Humans; Male; Middle Aged; Penicillamine; | 1988 |
Systemic sclerosis secondary to occupational exposure.
Topics: Adult; Chemical Industry; Humans; Male; Middle Aged; Occupational Diseases; Penicillamine; Phenylene | 1988 |
D-penicillamine induced crescentic glomerulonephritis: report and review of the literature.
Topics: Biopsy; Female; Glomerulonephritis; Hemoptysis; Humans; Kidney Glomerulus; Microscopy, Electron; Mid | 1987 |
Phenotype of peripheral blood lymphocytes in patients with progressive systemic sclerosis: activated T lymphocytes and the effect of D-penicillamine therapy.
Topics: Adult; Antibodies, Monoclonal; Antigens, Surface; Arthritis, Rheumatoid; Female; Humans; Lymphocyte | 1987 |
[Pulmonary involvement in progressive systemic sclerosis].
Topics: Humans; Hypertension, Pulmonary; Lung Diseases; Nifedipine; Penicillamine; Pulmonary Fibrosis; Scler | 1986 |
Bioavailability of D-penicillamine in relation to gastrointestinal involvement of generalized scleroderma.
Topics: Administration, Oral; Adult; Aged; Biological Availability; Capsules; Esophageal Diseases; Female; G | 1987 |
[Cholestatic hepatitis: a rare complication of the treatment with D. penicillamine].
Topics: Adult; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Female; Humans; Penicillam | 1987 |
D-penicillamine therapy and interstitial lung disease in scleroderma. A long-term followup study.
Topics: Carbon Monoxide; Diffusion; Follow-Up Studies; Humans; Lung; Penicillamine; Pulmonary Fibrosis; Resp | 1987 |
Scleroderma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Drug Therapy, Combination; Female; Glutamine; Hum | 1987 |
[Penicillamine in the treatment of patients with systemic scleroderma].
Topics: Adult; Ceruloplasmin; Copper; Female; Humans; Male; Middle Aged; Penicillamine; Scleroderma, Systemi | 1987 |
[Treatment of systemic scleroderma with D-penicillamine. Results in 14 patients treated for more than a year].
Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Male; Middle Aged; Penicillamine; Scleroderma, Syste | 1986 |
[Long-term use of D-penicillamine in systemic scleroderma and rheumatoid arthritis].
Topics: Adolescent; Adult; Aged; Arthritis, Juvenile; Arthritis, Rheumatoid; Female; Humans; Male; Middle Ag | 1986 |
Penicillamine-induced rapidly progressive glomerulonephritis in patients with progressive systemic sclerosis: successful treatment of two patients and a review of the literature.
Topics: Adolescent; Adult; Biopsy; Female; Glomerulonephritis; Humans; Kidney Glomerulus; Lupus Erythematosu | 1986 |
Systemic sclerosis-like lesions during long-term penicillamine therapy for Wilson's disease.
Topics: Adolescent; Hepatolenticular Degeneration; Humans; Male; Penicillamine; Scleroderma, Systemic | 1987 |
Bioavailability of D-penicillamine in a patient with gastrointestinal progressive systemic sclerosis.
Topics: Administration, Oral; Adult; Biological Availability; Enema; Fats; Feces; Gastrointestinal Diseases; | 1986 |
Penicillamine-induced polymyositis.
Topics: Female; Humans; Middle Aged; Myositis; Penicillamine; Scleroderma, Systemic | 1985 |
The effect of D-penicillamine on pulmonary findings in systemic sclerosis.
Topics: Colchicine; Female; Humans; Lung; Male; Penicillamine; Pulmonary Diffusing Capacity; Regression Anal | 1985 |
Pregnancy and progressive systemic sclerosis. Case report and review of the literature.
Topics: Adult; Blood Pressure; Colchicine; Female; Humans; Penicillamine; Prednisone; Pregnancy; Pregnancy C | 1985 |
[Progressive systemic sclerosis with pancytopenia, polymyositis and complete heart block developing after D-penicillamine therapy: a case report].
Topics: Aged; Female; Heart Block; Humans; Myositis; Pancytopenia; Penicillamine; Scleroderma, Systemic | 1985 |
Massive breast enlargement in a patient receiving D-penicillamine for systemic sclerosis.
Topics: Aged; Breast; Danazol; Female; Humans; Hyperprolactinemia; Penicillamine; Scleroderma, Systemic | 1985 |
[Treatment of generalized (progressive) scleroderma].
Topics: Ammotherapy; Female; Glucocorticoids; Heparinoids; Humans; Hyaluronoglucosaminidase; Male; Ointments | 1972 |
Biosynthesis and maturation of skin collagen in scleroderma, and effect of D-penicillamine.
Topics: Adolescent; Adult; Age Factors; Aged; Amino Acids; Animals; Biopsy; Collagen; Culture Techniques; Fe | 1974 |
[Rheumatic and pararheumatic diseases. Problems of diagnosis and therapy].
Topics: Antineoplastic Agents; Arthritis, Rheumatoid; Collagen Diseases; Dermatomyositis; Humans; Lupus Eryt | 1973 |
Effect of penicillamine on human collagen and its possible application to treatment of scleroderma.
Topics: Adult; Aged; Arthritis, Rheumatoid; Collagen; Cystinuria; Female; Hepatolenticular Degeneration; Hum | 1966 |
Decreased taste sensitivity after D-penicillamine reversed by copper administration.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Ceruloplasmin; Child; Copper; Cystinuria; Female; He | 1967 |
Nephropathy induced by D-penicillamine.
Topics: Adult; Arthritis, Rheumatoid; Complement System Proteins; Female; Fluorescent Antibody Technique; ga | 1968 |
Tryptophan metabolism in man (with special reference to rheumatoid arthritis and scleroderma).
Topics: Arthritis, Rheumatoid; Aspirin; Cystinuria; Drug Synergism; Edetic Acid; Humans; Kynurenic Acid; Kyn | 1973 |
Proceedings: Biosynthesis and maturation of skin collagen in scleroderma.
Topics: Biopsy; Collagen; Humans; Penicillamine; Protein Binding; Scleroderma, Systemic; Skin | 1974 |
The actionof D-penicillamine on collagen in scleroderma and osteoarthrosis.
Topics: Arthritis, Rheumatoid; Collagen; Humans; In Vitro Techniques; Osteoarthritis; Penicillamine; Sclerod | 1974 |
Two years of penicillamine for progressive systemic sclerosis: a case report.
Topics: Adolescent; Biopsy; Child; Female; Humans; Penicillamine; Scleroderma, Systemic | 1974 |
Penicillamine for systemic sclerosis?
Topics: Humans; Penicillamine; Scleroderma, Systemic | 1974 |
D-penicillamine in progressive scleroderma.
Topics: Adult; Aged; Biopsy; Blood Proteins; Blood Sedimentation; Collagen; Female; Hemoglobins; Humans; Hyd | 1972 |
Treatment of progressive systemic sclerosis (PSS) with penicillamine. Preliminary report of two cases.
Topics: Adult; Collagen; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Humans; Middle Aged; P | 1973 |
Progressive systemic sclerosis (scleroderma).
Topics: Adult; Aged; Calcinosis; Esophageal Diseases; Female; Heart Diseases; Humans; Intestinal Diseases; J | 1973 |
[Investigations on the mode of action of D-penicillamine (Metalcaptase) in sclerodermia].
Topics: Adult; Birefringence; Child; Female; Humans; Male; Microscopy, Electron; Microscopy, Polarization; M | 1973 |
Serial changes in scleroderma and idiopathic interstitial lung disease.
Topics: Adult; Aged; Arteries; Carbon Monoxide; Cyclophosphamide; Female; Humans; Lung Compliance; Male; Mer | 1973 |
[Therapeutic effect of d-penicillamine in scleroderma].
Topics: Adolescent; Adult; Arthritis, Rheumatoid; Evaluation Studies as Topic; Female; Humans; Male; Middle | 1973 |
[Treatment of "collagen and autoimmune" diseases (author's transl)].
Topics: Adolescent; Adult; Aminobenzoates; Azathioprine; Chloroquine; Cyclophosphamide; Dermatomyositis; Dex | 1973 |
[Penicillamine in the treatment of scleroderma].
Topics: Adult; Drug Evaluation; Female; Humans; Male; Middle Aged; Penicillamine; Proteinuria; Scleroderma, | 1973 |
[Ultrastructural comparative study of the behavior of collagen tissue and elastic tissue during 3 pathological states (Marfans disease, scleroderma due to vitamin K-1 lathyrogenic effect of penicillamine)].
Topics: Collagen; Collagen Diseases; Connective Tissue; Culture Techniques; Elastic Tissue; Elastin; Fibrobl | 1973 |
Monoclonal gammopathy penicillamine-induced polymyositis and systemic sclerosis.
Topics: Aged; Biopsy; Humans; Hypergammaglobulinemia; Japan; Male; Myositis; Penicillamine; Prednisolone; Sc | 1974 |
Progressive systemic sclerosis. Diagnosis at the age of 4 years.
Topics: Alopecia; Biopsy; Child, Preschool; Ectropion; Female; Foot Deformities, Acquired; Hand Deformities, | 1972 |
[Recent attempts at treatment of diffuse scleroderma].
Topics: Female; Humans; Male; Penicillamine; Scleroderma, Systemic | 1972 |
[Allergic-toxic liver damage due to D-penicillamine].
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Liver Functio | 1972 |
[Studies on the solubility of skin collagen in scleroderma and the effect of D-penicillamine].
Topics: Adult; Aged; Biopsy; Collagen; Female; Humans; Male; Middle Aged; Penicillamine; Scleroderma, Locali | 1972 |
[Marked proteinuria in the course of penicillamine treatment of progressive systemic sclerosis].
Topics: Humans; Middle Aged; Penicillamine; Proteinuria; Scleroderma, Systemic | 1971 |
Penicillamine for scleroderma.
Topics: Animals; Drug Hypersensitivity; Feeding and Eating Disorders; Humans; Joint Diseases; Leukopenia; Pe | 1968 |
[Treatment of progressive scleroderma with D-penicillamine (Metalcaptase)].
Topics: Adult; Collagen; Copper; Elasticity; Female; Humans; Middle Aged; Penicillamine; Scleroderma, System | 1969 |
Treatment of systemic sclerosis with D-penicillamine. A new method of observing the effects of treatment.
Topics: Adult; Aged; Elasticity; Female; Humans; Male; Middle Aged; Penicillamine; Proteinuria; Scleroderma, | 1970 |
Skin collagen in patients with scleroderma: biosynthesis and maturation in vitro, and the effect of D-penicillamine.
Topics: Adult; Aged; Biopsy; Carbon Isotopes; Collagen; Female; Humans; Hydroxyproline; In Vitro Techniques; | 1970 |
Management of scleroderma.
Topics: Aminobenzoates; Aminocaproates; Anti-Inflammatory Agents; Dimethyl Sulfoxide; Environment; Hormones; | 1971 |
Nephrotic syndrome induced by penicillamine.
Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Nephrotic Syndrome; Penicillamine; Scleroderma, | 1968 |
Loss of taste during therapy with penicillamine.
Topics: Adolescent; Adult; Cystinuria; Female; Food; Humans; Hydrochloric Acid; Male; Middle Aged; Penicilla | 1968 |
[Collagen diseases. On clinical aspects and theapy of disseminated lupus erythematosus, progressive scleroderma and dermatomyositis].
Topics: Collagen Diseases; Dermatomyositis; Humans; Immunosuppressive Agents; Lupus Erythematosus, Systemic; | 1969 |