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penicillamine and Pseudoxanthoma Elasticum

penicillamine has been researched along with Pseudoxanthoma Elasticum in 16 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Pseudoxanthoma Elasticum: An inherited disorder of connective tissue with extensive degeneration and calcification of ELASTIC TISSUE primarily in the skin, eye, and vasculature. At least two forms exist, autosomal recessive and autosomal dominant. This disorder is caused by mutations of one of the ATP-BINDING CASSETTE TRANSPORTERS. Patients are predisposed to MYOCARDIAL INFARCTION and GASTROINTESTINAL HEMORRHAGE.

Research Excerpts

ExcerptRelevanceReference
"A patient with cystinuria who was treated with large doses of D-penicillamine for 19 years developed skin abnormalities resembling those seen in pseudoxanthoma elasticum."7.67Collagen and elastin changes in D-penicillamine-induced pseudoxanthoma elasticum-like skin. ( Avery, NC; Fryer, PR; Kirby, JD; Light, N; Meyrick Thomas, RH; Stephens, A, 1986)
"We describe a 14-year-old boy with Wilson disease (WD) who first developed pseudo-pseudoxanthoma elasticum (PPXE) after 4."5.56Pediatric Pseudo-pseudoxanthoma Elasticum Resulting From D-Penicillamine Treatment for Wilson Disease. ( Corey, K; Hawryluk, EB; Schmidt, B; Sheu Song, J; Yu, Z, 2020)
"These patients had been treated for Wilson's disease since 14 and 16 years, respectively."5.33Elastosis perforans serpiginosa associated with pseudo-pseudoxanthoma elasticum during treatment of Wilson's disease with penicillamine. ( Balme, B; Bécuwe, C; Dalle, S; Kanitakis, J; Ronger-Savlé, S; Skowron, F; Thomas, L, 2005)
"Elastosis perforans serpiginosa (EPS) and the elastotic changes of pseudoxanthoma elasticum (PXE) are rare but well-recognized side-effects of long-term penicillamine therapy."3.69Penicillamine-induced elastosis perforans serpiginosa treated successfully with isotretinoin. ( Norris, PG; Ratnavel, RC, 1994)
"We have studied 23 patients receiving penicillamine for the treatment of rheumatoid arthritis to determine the prevalence of penicillamine-induced elastosis."3.68Elastic fibre damage induced by low-dose D-penicillamine. ( Burge, SM; Dalziel, KL; Frith, PA; Mowat, A; Ryan, TJ, 1990)
"A patient with cystinuria who was treated with large doses of D-penicillamine for 19 years developed skin abnormalities resembling those seen in pseudoxanthoma elasticum."3.67Collagen and elastin changes in D-penicillamine-induced pseudoxanthoma elasticum-like skin. ( Avery, NC; Fryer, PR; Kirby, JD; Light, N; Meyrick Thomas, RH; Stephens, A, 1986)
"We describe a 14-year-old boy with Wilson disease (WD) who first developed pseudo-pseudoxanthoma elasticum (PPXE) after 4."1.56Pediatric Pseudo-pseudoxanthoma Elasticum Resulting From D-Penicillamine Treatment for Wilson Disease. ( Corey, K; Hawryluk, EB; Schmidt, B; Sheu Song, J; Yu, Z, 2020)
"These patients had been treated for Wilson's disease since 14 and 16 years, respectively."1.33Elastosis perforans serpiginosa associated with pseudo-pseudoxanthoma elasticum during treatment of Wilson's disease with penicillamine. ( Balme, B; Bécuwe, C; Dalle, S; Kanitakis, J; Ronger-Savlé, S; Skowron, F; Thomas, L, 2005)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's5 (31.25)18.2507
2000's2 (12.50)29.6817
2010's1 (6.25)24.3611
2020's2 (12.50)2.80

Authors

AuthorsStudies
Sehgal, S1
Fazal, ZZ1
Gupta, L1
Sheeran, T1
Yu, Z1
Sheu Song, J1
Schmidt, B1
Corey, K1
Hawryluk, EB1
Ibáñez-Samaniego, L1
Ochoa-Palominos, A1
Catalina-Rodríguez, MV1
Salcedo-Plaza, M1
Clemente-Ricote, G1
Bécuwe, C1
Dalle, S1
Ronger-Savlé, S1
Skowron, F1
Balme, B1
Kanitakis, J1
Thomas, L1
Rayatt, S1
Pandey, U1
Khanna, A1
Meyrick Thomas, RH3
Light, N2
Stephens, AD1
Avery, NC2
Kirby, JD3
Ratnavel, RC1
Norris, PG1
Coatesworth, AP1
Darnton, SJ1
Green, RM1
Cayton, RM1
Antonakopoulos, GN1
Grahame, R1
Harvey, W1
Narron, GH1
Zec, N1
Neves, RI1
Manders, EK1
Sexton, FM1
Bolognia, JL1
Braverman, I1
Dalziel, KL1
Burge, SM1
Frith, PA1
Ryan, TJ1
Mowat, A1
Burge, S1
Ryan, T1
Stephens, A1
Fryer, PR1
Bentley-Phillips, B1

Other Studies

16 other studies available for penicillamine and Pseudoxanthoma Elasticum

ArticleYear
Progressive dermopathy akin to pseudoxanthoma elasticum after D-penicillamine use in a patient with cystinuria.
    Rheumatology (Oxford, England), 2022, 10-06, Volume: 61, Issue:10

    Topics: Cystinuria; Humans; Penicillamine; Pseudoxanthoma Elasticum

2022
Pediatric Pseudo-pseudoxanthoma Elasticum Resulting From D-Penicillamine Treatment for Wilson Disease.
    Journal of pediatric gastroenterology and nutrition, 2020, Volume: 71, Issue:6

    Topics: Adolescent; Adult; Hepatolenticular Degeneration; Humans; Male; Penicillamine; Pseudoxanthoma Elasti

2020
Penicillamine induced pseudo-pseudoxanthoma elasticum in a patient with Wilson's disease, which role plays the hepatologist?
    Revista espanola de enfermedades digestivas, 2015, Volume: 107, Issue:3

    Topics: Adult; Chelating Agents; Female; Hepatolenticular Degeneration; Humans; Penicillamine; Pseudoxanthom

2015
Elastosis perforans serpiginosa associated with pseudo-pseudoxanthoma elasticum during treatment of Wilson's disease with penicillamine.
    Dermatology (Basel, Switzerland), 2005, Volume: 210, Issue:1

    Topics: Adult; Chelating Agents; Diagnosis, Differential; Facial Dermatoses; Female; Hepatolenticular Degene

2005
Familial pseudo pseudoxanthoma elasticum.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2006, Volume: 59, Issue:10

    Topics: Cystinuria; Diagnosis, Differential; Drug Eruptions; Female; Humans; Middle Aged; Neck; Penicillamin

2006
Pseudoxanthoma elasticum-like skin changes induced by penicillamine.
    Journal of the Royal Society of Medicine, 1984, Volume: 77, Issue:9

    Topics: Axilla; Elastin; Humans; Male; Microscopy, Electron; Middle Aged; Penicillamine; Pseudoxanthoma Elas

1984
Penicillamine-induced elastosis perforans serpiginosa treated successfully with isotretinoin.
    Dermatology (Basel, Switzerland), 1994, Volume: 189, Issue:1

    Topics: Adult; Elastic Tissue; Female; Hepatolenticular Degeneration; Humans; Isotretinoin; Penicillamine; P

1994
A case of systemic pseudo-pseudoxanthoma elasticum with diverse symptomatology caused by long-term penicillamine use.
    Journal of clinical pathology, 1998, Volume: 51, Issue:2

    Topics: Chelating Agents; Drug Administration Schedule; Hepatolenticular Degeneration; Humans; Male; Middle

1998
Cutaneous extensibility in health and disease.
    Rheumatology and rehabilitation, 1975, Volume: 14, Issue:2

    Topics: Acromegaly; Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Collagen; Cutis Laxa; Ehlers-Da

1975
Penicillamine-induced pseudoxanthoma elasticum-like skin changes requiring rhytidectomy.
    Annals of plastic surgery, 1992, Volume: 29, Issue:4

    Topics: Adult; Facial Dermatoses; Female; Humans; Neck; Penicillamine; Pseudoxanthoma Elasticum; Rhytidoplas

1992
Pseudoxanthoma-elasticum-like skin changes induced by penicillamine.
    Dermatology (Basel, Switzerland), 1992, Volume: 184, Issue:1

    Topics: Aged; Collagen; Elastin; Humans; Male; Microscopy, Electron; Penicillamine; Pseudoxanthoma Elasticum

1992
Elastic fibre damage induced by low-dose D-penicillamine.
    The British journal of dermatology, 1990, Volume: 123, Issue:3

    Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Administration Schedule; Elastic Tissue; Female; Humans; Jo

1990
Penicillamine-induced pseudo-pseudoxanthoma elasticum in a patient with rheumatoid arthritis.
    Clinical and experimental dermatology, 1988, Volume: 13, Issue:4

    Topics: Arthritis, Rheumatoid; Female; Humans; Middle Aged; Penicillamine; Pseudoxanthoma Elasticum

1988
Collagen and elastin changes in D-penicillamine-induced pseudoxanthoma elasticum-like skin.
    The British journal of dermatology, 1986, Volume: 114, Issue:3

    Topics: Aged; Collagen; Elastin; Female; Humans; Male; Middle Aged; Penicillamine; Pseudoxanthoma Elasticum;

1986
Elastosis perforans serpiginosa and pseudoxanthoma elasticum-like skin change due to D-penicillamine.
    Clinical and experimental dermatology, 1985, Volume: 10, Issue:4

    Topics: Child; Connective Tissue Diseases; Female; Humans; Penicillamine; Pseudoxanthoma Elasticum; Skin

1985
Pseudoxanthoma elasticum-like skin changes induced by penicillamine.
    Journal of the Royal Society of Medicine, 1985, Volume: 78, Issue:9

    Topics: Adolescent; Female; Hepatolenticular Degeneration; Humans; Penicillamine; Pseudoxanthoma Elasticum

1985