penicillamine has been researched along with Polyarthritis in 87 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twelve patients with rheumatoid arthritis who had failed to respond to or developed side effects preventing further use of penicillamine were given 5-thiopyridoxine (5-TP)." | 9.05 | 5-Thiopyridoxine in rheumatoid arthritis: clinical and experimental studies. ( Dieppe, PA; Huskisson, EC; Jaffe, IA; Scott, J, 1980) |
| "The effects of long term D-penicillamine treatment on adjuvant arthritis in the rat were determined in order to establish a possible approach to the laboratory evaluation of anti-rheumatic drugs." | 7.67 | Prolonged treatment with D-penicillamine: effects on adjuvant arthritis in the rat. ( Branceni, D; Delahaye, M; Dunn, CJ; Prouteau, M; Purcell, T, 1984) |
| "Experiments were performed in order to ascertain the action of D-penicillamine (PA) on adjuvant arthritis (AA) in rats and to develop a quantitative evaluation method for PA-like drugs, using Lewis, SD, and Wistar rats." | 7.67 | Studies of D-penicillamine on strain variability and lymph node cellularity in adjuvant arthritis. ( Aihara, H; Nakaike, S; Otomo, S; Shiono, M; Takeshita, K; Tomita, N, 1985) |
| " D-penicillamine, a drug effective in the proliferative synovitis of rheumatoid arthritis, was evaluated in a rabbit model of hemarthroses-induced arthritis and in four hemophiliacs with chronic synovitis." | 7.67 | Treatment of hemophilic arthritis with D-penicillamine: a preliminary report. ( Corrigan, JJ; Damiano, ML; Gall, EP; Jeter, M; Kolba, KS; Meredith, K; Trombley, J, 1985) |
| "D-Penicillamine (D-PA), 80-100 mg/kg/day enhanced the early phase of adjuvant arthritis (AA) in rats when it was administered orally for about 4 weeks after the adjuvant injection day, whereas dexamethasone (1 mg/kg/day, p." | 7.66 | [Studies of D-penicillamine (5): effects on rat adjuvant arthritis (author's transl)]. ( Higuchi, S; Kimura, M; Nakaike, S; Ohzeki, M; Otomo, S; Sasajima, M; Tarumoto, Y, 1981) |
| "Treatment of rabbits with D-penicillamine at doses up to 30 mg/kg, beginning either before or after the onset of antigen-induced experimental arthritis, diminished the severity of the inflammatory synovitis in a considerable proportion of animals as judged by both external joint measurements and terminal histopathological assessment." | 7.66 | Effect of oral D-penicillamine treatment on experimental arthritis and associated immune responses in rabbits. III: Reduction of the monoarticular arthritis. ( Hunneyball, IM; Stanworth, DR; Stewart, GA, 1979) |
| "Prolonged oral treatment (up to 410 days) of rabbits with D-penicillamine at a dose of 15 mg/kg body weight commencing either before or after immunization and the onset of arthritis, diminished and eventually abolished the delayed hypersensitivity response to intradermally administered tuberculin PPD." | 7.66 | The effects of oral D-penicillamine treatment on experimental arthritis and the associated immune response in rabbits. II. The effects on cellular parameters. ( Hunneyball, IM; Stanworth, DR; Stewart, GA, 1978) |
| "Preliminary observations on the effect of D(-)penicillamine on chronic antigen-induced experimental arthritis in rabbits are reported." | 7.65 | Effect of D(-)penicillamine on chronic experimental arthritis in rabbits. ( Hunneyball, IM; Stanworth, DR; Stewart, GA, 1977) |
| "SA679 also inhibited the adjuvant arthritis at a dose of 100 mg/kg, but its effect was less potent than that of SA96." | 5.27 | [Pharmacological studies on N-(2-mercapto-2-methylpropanoyl)-L-cysteine(SA96). IV. Effects of SA96 and its main metabolite, SA679, on denaturation of human gamma-globulin and adjuvant arthritis in rats]. ( Hayashi, M; Iso, T; Kasamatsu, S; Nakata, K; Sasano, M; Suda, H; Yamauchi, H, 1985) |
| "Twelve patients with rheumatoid arthritis who had failed to respond to or developed side effects preventing further use of penicillamine were given 5-thiopyridoxine (5-TP)." | 5.05 | 5-Thiopyridoxine in rheumatoid arthritis: clinical and experimental studies. ( Dieppe, PA; Huskisson, EC; Jaffe, IA; Scott, J, 1980) |
| " Injectable gold compounds and penicillamine are not contraindicated in the elderly, because they are just as efficacious as in younger persons for the treatment of rheumatoid arthritis." | 4.76 | Problems of antiarthritic therapy in the elderly. ( Brooks, PM; Buchanan, WW; Kassam, Y; Kean, WF, 1984) |
| "The effects of long term D-penicillamine treatment on adjuvant arthritis in the rat were determined in order to establish a possible approach to the laboratory evaluation of anti-rheumatic drugs." | 3.67 | Prolonged treatment with D-penicillamine: effects on adjuvant arthritis in the rat. ( Branceni, D; Delahaye, M; Dunn, CJ; Prouteau, M; Purcell, T, 1984) |
| "Experiments were performed in order to ascertain the action of D-penicillamine (PA) on adjuvant arthritis (AA) in rats and to develop a quantitative evaluation method for PA-like drugs, using Lewis, SD, and Wistar rats." | 3.67 | Studies of D-penicillamine on strain variability and lymph node cellularity in adjuvant arthritis. ( Aihara, H; Nakaike, S; Otomo, S; Shiono, M; Takeshita, K; Tomita, N, 1985) |
| " D-penicillamine, a drug effective in the proliferative synovitis of rheumatoid arthritis, was evaluated in a rabbit model of hemarthroses-induced arthritis and in four hemophiliacs with chronic synovitis." | 3.67 | Treatment of hemophilic arthritis with D-penicillamine: a preliminary report. ( Corrigan, JJ; Damiano, ML; Gall, EP; Jeter, M; Kolba, KS; Meredith, K; Trombley, J, 1985) |
| "Adherent spleen cells from rats with adjuvant arthritis inhibit the incorporation of 3H-thymidine into DNA and 3H-leucine into protein in nonadherent spleen lymphocytes, stimulated by the mitogens Concanavalin A and E." | 3.66 | Splenic suppressor cells in adjuvant arthritic rats: effect of D-penicillamine. ( Arrigoni-Martelli, E; Binderup, L; Bramm, E, 1980) |
| "D-Penicillamine (D-PA), 80-100 mg/kg/day enhanced the early phase of adjuvant arthritis (AA) in rats when it was administered orally for about 4 weeks after the adjuvant injection day, whereas dexamethasone (1 mg/kg/day, p." | 3.66 | [Studies of D-penicillamine (5): effects on rat adjuvant arthritis (author's transl)]. ( Higuchi, S; Kimura, M; Nakaike, S; Ohzeki, M; Otomo, S; Sasajima, M; Tarumoto, Y, 1981) |
| "D-penicillamine (D-PA) has beneficial therapeutic effects for patients with rheumatoid arthritis but no convincing explanation has been offered for the mode of action." | 3.66 | Studies of D-penicillamine (3): immunomodulating effects of D-penicillamine. ( Mori, C; Nakaike, S; Ohzeki, M; Otomo, S; Tsuji, I, 1981) |
| "Administration of D-penicillamine (50 mg/kg/day orally) to rats with adjuvant arthritis for up to 42 days significantly modified the incorporation of 3H-thymidine (3H-TdR) in concanavalin A (Con A)-stimulated lymph node cells." | 3.66 | Immunological effects of D-penicillamine during experimental induced inflammation in rats. ( Arrigoni-Martelli, E; Binderup, L; Bramm, E, 1980) |
| "Treatment of rabbits with D-penicillamine at doses up to 30 mg/kg, beginning either before or after the onset of antigen-induced experimental arthritis, diminished the severity of the inflammatory synovitis in a considerable proportion of animals as judged by both external joint measurements and terminal histopathological assessment." | 3.66 | Effect of oral D-penicillamine treatment on experimental arthritis and associated immune responses in rabbits. III: Reduction of the monoarticular arthritis. ( Hunneyball, IM; Stanworth, DR; Stewart, GA, 1979) |
| "Prolonged oral treatment (up to 410 days) of rabbits with D-penicillamine at a dose of 15 mg/kg body weight commencing either before or after immunization and the onset of arthritis, diminished and eventually abolished the delayed hypersensitivity response to intradermally administered tuberculin PPD." | 3.66 | The effects of oral D-penicillamine treatment on experimental arthritis and the associated immune response in rabbits. II. The effects on cellular parameters. ( Hunneyball, IM; Stanworth, DR; Stewart, GA, 1978) |
| "Preliminary observations on the effect of D(-)penicillamine on chronic antigen-induced experimental arthritis in rabbits are reported." | 3.65 | Effect of D(-)penicillamine on chronic experimental arthritis in rabbits. ( Hunneyball, IM; Stanworth, DR; Stewart, GA, 1977) |
| " A preliminary bioavailability study of two of the lead structures is presented." | 1.27 | Antiinflammatory activity of substituted 6-hydroxypyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-triones. Atypical nonsteroidal antiinflammatory agents. ( Blythin, DJ; Bober, LA; Chiu, PJ; Conn, DJ; Domalski, MS; Kaminski, JJ; Solomon, DM; Spitler, J; Verbiar, LL; Wong, SC, 1986) |
| "SA679 also inhibited the adjuvant arthritis at a dose of 100 mg/kg, but its effect was less potent than that of SA96." | 1.27 | [Pharmacological studies on N-(2-mercapto-2-methylpropanoyl)-L-cysteine(SA96). IV. Effects of SA96 and its main metabolite, SA679, on denaturation of human gamma-globulin and adjuvant arthritis in rats]. ( Hayashi, M; Iso, T; Kasamatsu, S; Nakata, K; Sasano, M; Suda, H; Yamauchi, H, 1985) |
| "actions, which can be disclosed in the adjuvant arthritis as well as in the B." | 1.27 | [The testing of long-term antirheumatics in animals]. ( Bekemeier, H; Hirschelmann, R; Weber, M, 1987) |
| " During gradual reduction of the steroid dosage osteocalcin returned to pretreatment values." | 1.27 | Serum osteocalcin in rheumatoid arthritis and other inflammatory arthritides: relation between inflammatory activity and the effect of glucocorticoids and remission inducing drugs. ( Ekenstam, EA; Hällgren, R; Ljunghall, S, 1986) |
| " This result indicates that long-term administration of the drug may alter the collagen composition of synovial tissue matrix in rheumatoid arthritis." | 1.27 | In vitro production of collagen by synovial fibroblasts from D-penicillamine-treated arthritic rabbits. ( Béliard, R; Bocquet, J; Brisset, M; Farjanel, J; Loyau, G; Penfornis, H; Pujol, JP; Rattner, A, 1986) |
| "adjuvant arthritis, were found to increase tumour cell 3H-TdR incorporation, compared to macrophages from nonarthritic rats." | 1.26 | Antirheumatic drugs and macrophage function: effects on tumour cell growth in vitro. ( Arrigoni-Martelli, E; Binderup, L; Bramm, E, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 81 (93.10) | 18.7374 |
| 1990's | 4 (4.60) | 18.2507 |
| 2000's | 1 (1.15) | 29.6817 |
| 2010's | 1 (1.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blythin, DJ | 1 |
| Kaminski, JJ | 1 |
| Domalski, MS | 1 |
| Spitler, J | 1 |
| Solomon, DM | 1 |
| Conn, DJ | 1 |
| Wong, SC | 1 |
| Verbiar, LL | 1 |
| Bober, LA | 1 |
| Chiu, PJ | 1 |
| Gucev, ZS | 1 |
| Pop-Jordanova, N | 1 |
| Calovska, V | 1 |
| Tasic, V | 1 |
| Slavevska, N | 1 |
| Laban, N | 1 |
| Noli, MC | 1 |
| Lepori, MB | 1 |
| Loudianos, G | 1 |
| JAFFE, IA | 3 |
| OPDECOUL, AA | 1 |
| RUBENS, A | 1 |
| CORCOS, JM | 1 |
| SOLER-BECHARA, J | 1 |
| MAYER, K | 1 |
| FREYBERG, RH | 1 |
| GOLDSTEIN, R | 1 |
| JAFFE, I | 1 |
| PROHASKA, E | 1 |
| SCHWAEGERL, W | 1 |
| JESSERER, H | 1 |
| Brooks, PM | 1 |
| Kean, WF | 1 |
| Kassam, Y | 1 |
| Buchanan, WW | 1 |
| Lewis, AJ | 1 |
| Carlson, RP | 1 |
| Chang, J | 1 |
| DeLustro, F | 1 |
| Binderup, L | 4 |
| Bramm, E | 5 |
| Arrigoni-Martelli, E | 5 |
| Bhalla, AK | 1 |
| Simon, LS | 1 |
| Neuberger, GB | 1 |
| West, GB | 1 |
| Dunn, CJ | 1 |
| Prouteau, M | 1 |
| Delahaye, M | 1 |
| Purcell, T | 1 |
| Branceni, D | 1 |
| Langlands, DR | 1 |
| Dawkins, RL | 1 |
| Matz, LR | 1 |
| Cobain, TJ | 1 |
| Goatcher, P | 1 |
| Papadimitriou, JM | 1 |
| Cohen, ML | 1 |
| Cashin, CH | 2 |
| Doherty, NS | 1 |
| Jeffries, BL | 1 |
| Buckland-Wright, JC | 1 |
| Sloboda, AE | 1 |
| Birnbaum, JE | 1 |
| Oronsky, AL | 1 |
| Kerwar, SS | 1 |
| Otomo, S | 3 |
| Higuchi, S | 1 |
| Nakaike, S | 3 |
| Tarumoto, Y | 1 |
| Kimura, M | 1 |
| Sasajima, M | 1 |
| Ohzeki, M | 2 |
| Tsuji, I | 1 |
| Mori, C | 1 |
| Ehrlich, GE | 1 |
| Lipsky, PE | 1 |
| Huskisson, EC | 1 |
| Scott, J | 1 |
| Dieppe, PA | 1 |
| Hardo, HG | 1 |
| Holden, G | 1 |
| Jones, SA | 1 |
| Kennedy, AJ | 1 |
| Roberts, NA | 1 |
| Brouilhet, H | 2 |
| Rabaud, M | 2 |
| Boucherie, S | 2 |
| Mach, PS | 1 |
| Delbarre, F | 1 |
| Dryll, A | 1 |
| Sack, KE | 1 |
| Nishikaku, F | 1 |
| Aono, S | 1 |
| Koga, Y | 1 |
| Gaskin, G | 1 |
| Thompson, EM | 1 |
| Pusey, CD | 1 |
| Miura, M | 1 |
| Okabe, T | 1 |
| Tsubata, S | 1 |
| Takizawa, N | 1 |
| Sawaguchi, T | 1 |
| Elston, DM | 1 |
| Seipelt, H | 1 |
| Kennedy, C | 1 |
| Hodge, L | 1 |
| Sanderson, KV | 1 |
| Chlud, K | 2 |
| Eberl, R | 1 |
| Hunneyball, IM | 6 |
| Stewart, GA | 4 |
| Stanworth, DR | 4 |
| Miehle, W | 1 |
| Marqués, J | 1 |
| López Pallarés, P | 1 |
| Barceló, P | 1 |
| Brühl, W | 1 |
| Cygler, B | 1 |
| Woźniczko-Orłowska, G | 1 |
| Chrzczonowski, Z | 2 |
| Dyznarowska, H | 1 |
| Doerwald, K | 1 |
| Humrich, A | 1 |
| Krebber, K | 1 |
| Kriegel, W | 1 |
| Arrigoni-Martelld, E | 1 |
| Nasonova, VA | 1 |
| Matulis, AA | 1 |
| Trofimova, TM | 1 |
| Olhagen, B | 1 |
| Kahn, MF | 1 |
| Roux, H | 1 |
| Maestracci, D | 1 |
| Recordier, AM | 1 |
| Hirschelmann, R | 2 |
| Bekemeier, H | 2 |
| Reimann, S | 1 |
| Schobess, B | 1 |
| McQuaid, A | 1 |
| Lamand, M | 1 |
| Mason, J | 1 |
| Yamauchi, H | 1 |
| Hayashi, M | 1 |
| Kasamatsu, S | 1 |
| Suda, H | 1 |
| Nakata, K | 1 |
| Sasano, M | 1 |
| Iso, T | 1 |
| Weber, M | 1 |
| Crossley, MJ | 2 |
| Spowage, M | 2 |
| Grondin, C | 1 |
| Malleson, P | 1 |
| Petty, RE | 1 |
| Panayi, GS | 1 |
| Mills, MM | 1 |
| Kaschak, TJ | 1 |
| Edworthy, S | 1 |
| Ekenstam, EA | 1 |
| Ljunghall, S | 1 |
| Hällgren, R | 2 |
| Brisset, M | 1 |
| Pujol, JP | 2 |
| Penfornis, H | 1 |
| Farjanel, J | 1 |
| Rattner, A | 1 |
| Bocquet, J | 2 |
| Béliard, R | 2 |
| Loyau, G | 2 |
| Fontagne, J | 1 |
| Loizeau, M | 1 |
| Perret, C | 1 |
| Semichon, M | 1 |
| Lechat, P | 1 |
| Connolly, KM | 1 |
| Stecher, VJ | 1 |
| Danis, E | 1 |
| Pruden, DJ | 1 |
| LaBrie, T | 1 |
| Rainsford, KD | 1 |
| Legendre, P | 1 |
| Daireaux, M | 1 |
| Langris, M | 1 |
| Svenson, KL | 1 |
| Lithell, H | 1 |
| Vessby, B | 1 |
| Price, R | 1 |
| Gibson, T | 1 |
| Craft, AW | 1 |
| Pasternak, RD | 1 |
| Marks, RL | 1 |
| Hubbs, SJ | 1 |
| DiPasquale, G | 1 |
| Takeshita, K | 1 |
| Shiono, M | 1 |
| Tomita, N | 1 |
| Aihara, H | 1 |
| Ziminski, CM | 1 |
| Corrigan, JJ | 1 |
| Kolba, KS | 1 |
| Gall, EP | 1 |
| Trombley, J | 1 |
| Damiano, ML | 1 |
| Meredith, K | 1 |
| Jeter, M | 1 |
| Baumgartner, R | 2 |
| Obenaus, H | 2 |
| Stoerk, HC | 2 |
| Anderson, AJ | 1 |
| Raab, W | 1 |
| Liyanage, SP | 1 |
| Currey, HL | 1 |
| Steinetz, B | 1 |
| Giannina, T | 1 |
| Butler, M | 1 |
| Miksić, J | 1 |
| Stern, M | 1 |
| Stern, P | 1 |
| Gmaz-Nikulin, E | 1 |
| Beritić, T | 1 |
| Miehlke, K | 1 |
| Klamer, B | 1 |
| Kimura, ET | 1 |
| Makstenieks, M | 1 |
| Sancilio, LF | 1 |
8 reviews available for penicillamine and Polyarthritis
| Article | Year |
|---|---|
Problems of antiarthritic therapy in the elderly.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Allopurinol; Anti-Inflammatory Agents; Anti-Inflammatory | 1984 |
Palindromic rheumatism: a review.
Topics: Adult; Arthritis; Chondrocalcinosis; Diagnosis, Differential; Female; Gold; Gout; Humans; Male; Midd | 1981 |
[Possibilities of drug therapy in monoarticular and oligoarticular diseases].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis; Arthritis | 1979 |
Slow-acting antirheumatic drugs in chronic arthritis of childhood.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Arthritis; Child; Drug Evaluation; Gold; Hum | 1988 |
Pharmacologic management of inflammatory joint disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antimetabolites; Arthritis; Gold; Gout; Huma | 1988 |
Actions of nonsteroidal anti-inflammatory drugs on the functions of lymphocytes.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Cyclooxygenase Inhibitors; Cyclosporins | 1988 |
Arthritis in children.
Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Juvenile; Child; Child, Preschool; Chronic Disease; | 1985 |
[Penicillamine in the light of current clinical research].
Topics: Antidotes; Arthritis; Arthritis, Rheumatoid; Chronic Disease; Collagen; Copper; Depression, Chemical | 1970 |
2 trials available for penicillamine and Polyarthritis
| Article | Year |
|---|---|
5-Thiopyridoxine in rheumatoid arthritis: clinical and experimental studies.
Topics: Animals; Arthritis; Arthritis, Rheumatoid; Clinical Trials as Topic; Copper; Humans; Kynurenine; Mal | 1980 |
[Letter: D penicillamine and psoriatic polyarthritis].
Topics: Arthritis; Clinical Trials as Topic; Follow-Up Studies; Humans; Penicillamine; Psoriasis; Rheumatic | 1975 |
77 other studies available for penicillamine and Polyarthritis
| Article | Year |
|---|---|
Antiinflammatory activity of substituted 6-hydroxypyrimido[2,1-f]purine-2,4,8(1H,3H,9H)-triones. Atypical nonsteroidal antiinflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Biological Availability; Cyclooxygenase Inhibitors; Ga | 1986 |
Acute Gallbladder Hydrops and Arthritis: unusual initial manifestations of Wilson's Disease (WD): Case Report.
Topics: Adenosine Triphosphatases; Arthritis; Cation Transport Proteins; Ceruloplasmin; Chelating Agents; Ch | 2011 |
Comparison of the effect of plasmapheresis and penicillamine on the level of circulating rheumatoid factor.
Topics: Arthritis; Arthritis, Rheumatoid; Chelating Agents; Humans; Immunologic Tests; Penicillamine; Plasma | 1963 |
[PSYCHOSIS DUE TO GOLD POISONING, TREATED WITH D-PENICILLAMINE].
Topics: Arthritis; Arthritis, Rheumatoid; Gold; Humans; Iatrogenic Disease; Mental Disorders; Penicillamine; | 1964 |
NEUTROPHILIC AGRANULOCYTOSIS DURING ADMINISTRATION OF PENICILLAMINE.
Topics: Adrenal Cortex Hormones; Agranulocytosis; Arthritis; Arthritis, Rheumatoid; Bone Marrow Examination; | 1964 |
RHEUMATOID ARTHRITIS WITH ARTERITIS; REPORT OF A CASE TREATED WITH PENICILLAMINE.
Topics: Amputation, Surgical; Arteritis; Arthritis; Arthritis, Rheumatoid; Drug Therapy; Foot Diseases; Gang | 1964 |
[ON THE BEHAVIOR OF THE RHEUMATOID FACTOR UNDER THE INFLUENCE OF PENICILLAMINE AND PENICILLIN IN PRIMARY CHRONIC POLYARTHRITIS (RHEUMATOID ARTHRITIS)].
Topics: Arthritis; Arthritis, Rheumatoid; Hemagglutination; Hemagglutination Tests; Humans; Immunologic Test | 1965 |
Effect of gold salts, D-penicillamine and benoxaprofen on type II collagen-induced arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents; Antibodies; Arthritis; Auranofin; Aurothioglucose; Collagen; Copp | 1984 |
Splenic suppressor cells in adjuvant arthritic rats: effect of D-penicillamine.
Topics: Animals; Arthritis; Arthritis, Experimental; Cell Adhesion; Concanavalin A; Female; Leucine; Lipopol | 1980 |
A clinical evaluation of the antiarthritic agents.
Topics: Anti-Inflammatory Agents; Antimalarials; Arthritis; Aspirin; Diflunisal; Fenoprofen; Glucocorticoids | 1984 |
The role of the nurse with arthritis patients on drug therapy.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antipyrine; Arthritis; Gold; Humans; Hydroxychlor | 1984 |
Anti-rheumatic agents and leucocyte migration.
Topics: Animals; Arthritis; Arthritis, Experimental; Chemotaxis, Leukocyte; Levamisole; Passive Cutaneous An | 1983 |
Prolonged treatment with D-penicillamine: effects on adjuvant arthritis in the rat.
Topics: Administration, Oral; Animals; Arthritis; Arthritis, Experimental; Body Weight; Drug Evaluation, Pre | 1984 |
Arthritis associated with a crystallizing cryoprecipitable IgG paraprotein.
Topics: Arthritis; Complement Activation; Cornea; Cryoglobulins; Crystallization; Humans; Immunoglobulin G; | 1980 |
An investigation of the effect of anti-inflammatory and anti-rheumatoid drugs in cell-mediated immune arthritis in guinea-pigs by microfocal radiography.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Chloroquine; Disease Models, | 1980 |
Studies on type II collagen-induced polyarthritis in rats. Effect of antiinflammatory and antirheumatic agents.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthrography; Aurothioglucose; Collagen; Disease Model | 1981 |
[Studies of D-penicillamine (5): effects on rat adjuvant arthritis (author's transl)].
Topics: Administration, Oral; Animals; Arthritis; Arthritis, Experimental; Chloroquine; Dexamethasone; Femal | 1981 |
Studies of D-penicillamine (3): immunomodulating effects of D-penicillamine.
Topics: Adjuvants, Immunologic; Animals; Arthritis; Arthritis, Experimental; Concanavalin A; Dose-Response R | 1981 |
Medical management and its impact on work.
Topics: Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Female; | 1982 |
Immunological effects of D-penicillamine during experimental induced inflammation in rats.
Topics: Animals; Arthritis; Arthritis, Experimental; Cell Adhesion; Cell Separation; Concanavalin A; Female; | 1980 |
Modulation of T lymphocyte function by copper and thiols.
Topics: Adult; Anti-Inflammatory Agents; Arthritis; Cell Division; Cells, Cultured; Copper; Humans; In Vitro | 1981 |
Antirheumatic drugs and macrophage function: effects on tumour cell growth in vitro.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Chloroquine; Female; Levamiso | 1982 |
Age and arthritis.
Topics: Adult; Age Factors; Aged; Arthritis; Arthritis, Rheumatoid; England; Female; Gold; Humans; Male; Mid | 1982 |
Assessment of drugs for activity in established type II collagen arthritis.
Topics: Animals; Anti-Inflammatory Agents; Antibody Formation; Arthritis; Arthritis, Experimental; Collagen; | 1982 |
Comparison of effects of D. Penicillamine and dexamethasone on the articular and non articular lesions in immune connective tissue disease induced in rabbits.
Topics: Animals; Antibody Formation; Arthritis; Connective Tissue Diseases; Dexamethasone; Kidney; Liver; Lu | 1982 |
Arthritis: specifics on long-term management. Part II.
Topics: Anti-Inflammatory Agents; Arthritis; Gold; Humans; Immunosuppressive Agents; Indomethacin; Penicilla | 1980 |
Protective effects of D-penicillamine and a thiazole derivative, SM-8849, on pristane-induced arthritis in mice.
Topics: Adjuvants, Immunologic; Animals; Arthritis; Biphenyl Compounds; Carrier Proteins; Hyaluronan Recepto | 1994 |
Goodpasture-like syndrome associated with anti-myeloperoxidase antibodies following penicillamine treatment.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Antibodies, Antineutrophil Cytoplasmic; Antirheuma | 1995 |
Chronic infantile neurological cutaneous articular syndrome in a patient from Japan.
Topics: Age of Onset; Antirheumatic Agents; Arthritis; Central Nervous System Diseases; Eye Diseases; Female | 1997 |
Photo quiz. Drug-induced pemphigus foliaceus.
Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Stero | 2000 |
[Drug immunosuppression].
Topics: Alkylating Agents; Anemia, Hemolytic, Autoimmune; Antimetabolites; Arthritis; Arthritis, Juvenile; A | 1975 |
Skin changes caused by D-penicillamine treatment of arthritis. Report of three cases with immunological findings.
Topics: Arthritis; Child; Drug Eruptions; Female; Humans; Immunoglobulin G; Male; Middle Aged; Penicillamine | 1978 |
Characterization of inhibitor(s) of lymphocyte activation in serum from rats with adjuvant arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Chemical Fractionation; Chromatography, Gel; Concanaval | 1978 |
[Basic treatment for chronic polyarthritis].
Topics: Arthritis; Chloroquine; Chronic Disease; Gold; Humans; Immunosuppressive Agents; Mouth Mucosa; Penic | 1977 |
Effect of oral D-penicillamine treatment on experimental arthritis and associated immune responses in rabbits. III: Reduction of the monoarticular arthritis.
Topics: Animals; Antibody Formation; Arthritis; Arthritis, Experimental; Blood Cell Count; Chronic Disease; | 1979 |
Penicillamine in experimental models of immunologically mediated inflammation.
Topics: Animals; Arthritis; Arthritis, Experimental; Edema; Levamisole; Penicillamine; Pertussis Vaccine; Ra | 1979 |
[The Reiter syndrome. 2. Diagnosis, therapy, prognosis].
Topics: Arthritis; Arthritis, Reactive; Chloroquine; Gold; Humans; Immunosuppressive Agents; Osteoporosis; P | 1979 |
[Diplopia caused by D-penicillamine].
Topics: Adult; Arthritis; Diplopia; Dose-Response Relationship, Drug; Female; Humans; Penicillamine | 1979 |
[Effect of D-penicillamine treatment of chronic arthritis on indices of humoral immunity].
Topics: Adult; Aged; Antibody Formation; Arthritis; Female; Humans; Immunoglobulins; Male; Middle Aged; Peni | 1978 |
The effects of oral D-penicillamine treatment on experimental arthritis and the associated immune response in rabbits.
Topics: Administration, Oral; Animals; Antibody Formation; Arthritis; Female; Immunoglobulins; Male; Ovalbum | 1978 |
The effects of oral D-penicillamine treatment on experimental arthritis and the associated immune response in rabbits. II. The effects on cellular parameters.
Topics: Animals; Arthritis; Cell Migration Inhibition; Female; Hypersensitivity, Delayed; Immunity, Cellular | 1978 |
[Scintigraphic studies of the course of primary chronic polyarthritis after basic therapy with gold salts and with D-penicillamine].
Topics: Adult; Aged; Arthritis; Arthritis, Rheumatoid; Female; Gold; Humans; Male; Middle Aged; Penicillamin | 1978 |
Investigations on the influence of cyclophosphamide, gold sodium thiomalate and D-penicillamine on nystatin oedema and adjuvant arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Cyclophosphamide; Disease Models, Animal; Female; Gold | 1975 |
Effect of D(-)penicillamine on chronic experimental arthritis in rabbits.
Topics: Animals; Arthritis; Arthritis, Experimental; Biometry; Hindlimb; Penicillamine; Rabbits | 1977 |
[Problems in the treatment of joing diseases (according to data of the 4th Congress of Rheumatologists GDR, Weimar, September 11-13, 1974)].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthriti | 1975 |
[Immunosuppressive treatment of rheumatologic diseases].
Topics: Arthritis; Arthritis, Rheumatoid; Drug Evaluation; Female; Humans; Immunity, Cellular; Immunosuppres | 1976 |
Medical treatment of chronic inflammatory rheumatic diseases.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthritis; Chronic Disease; Gold; | 1975 |
6-Sulfanilamidoindazole arthritis: influence of alloxan diabetes, phenylbutazone and D-penicillamine on inflammatory size, sulfhydryl groups, diphenylamine reaction and enzymes of the serum.
Topics: Alkaline Phosphatase; Animals; Arthritis; Blood Glucose; Diabetes Mellitus, Experimental; Diphenylam | 1975 |
The interactions of penicillamine with copper in vivo and the effect on hepatic metallothionein levels and copper/zinc distribution: the implications for Wilson's disease and arthritis therapy.
Topics: Animals; Arthritis; Copper; Cytosol; Hepatolenticular Degeneration; Humans; Injections, Intramuscula | 1992 |
[Pharmacological studies on N-(2-mercapto-2-methylpropanoyl)-L-cysteine(SA96). IV. Effects of SA96 and its main metabolite, SA679, on denaturation of human gamma-globulin and adjuvant arthritis in rats].
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Cysteine; gamma-Globulins; In | 1985 |
[The testing of long-term antirheumatics in animals].
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Chloroquine; Copper; Delayed- | 1987 |
Pharmacological studies of antigen-induced arthritis in BALB/c mice. II. The effects of second-line antirheumatic drugs and cytotoxic agents on the histopathological changes.
Topics: Animals; Arthritis; Arthritis, Experimental; Chloroquine; Dapsone; Female; Gold Sodium Thiomalate; M | 1986 |
Studies on the effects of pharmacological agents on antigen-induced arthritis in BALB/c mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Arthritis; Arthritis, Experimental; Azat | 1987 |
Second-line drug treatment in rheumatoid arthritis associated with depressed autologous mixed lymphocyte reaction.
Topics: Arthritis; Arthritis, Rheumatoid; Gold Sodium Thiomalate; Humans; Lymphocyte Culture Test, Mixed; Pe | 1986 |
Serum osteocalcin in rheumatoid arthritis and other inflammatory arthritides: relation between inflammatory activity and the effect of glucocorticoids and remission inducing drugs.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Arthritis; Arthritis, Rheumatoid; Azathioprine; Calcium-Bi | 1986 |
In vitro production of collagen by synovial fibroblasts from D-penicillamine-treated arthritic rabbits.
Topics: Animals; Arthritis; Collagen; Fibroblasts; In Vitro Techniques; Male; Penicillamine; Procollagen; Pr | 1986 |
Effects of long-term treatment with D-penicillamine on antigen-induced arthritis in rabbits: studies on in vivo articular chondrocyte damage and in vitro collagen biosynthesis by cultured chondrocytes.
Topics: Animals; Antigens; Arthritis; Arthritis, Experimental; Cartilage, Articular; Collagen; Male; Mycobac | 1987 |
Alteration of interleukin-1 activity and the acute phase response in adjuvant arthritic rats treated with disease modifying antirheumatic drugs.
Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Experi | 1988 |
Effects of an in vivo D-penicillamine treatment on glycosaminoglycan biosynthesis by synovial fibroblasts from arthritic-rendered rabbits.
Topics: Animals; Arthritis; Arthritis, Experimental; Cells, Cultured; Chromatography, Affinity; Chromatograp | 1988 |
The induction of an erosive arthropathy in the guinea pig with copper II bisglycinate and its treatment with antirheumatic drugs.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Disease Models, Animal; Glycine | 1987 |
Serum lipoprotein in active rheumatoid arthritis and other chronic inflammatory arthritides. II. Effects of anti-inflammatory and disease-modifying drug treatment.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis | 1987 |
D-penicillamine and psoriatic arthropathy.
Topics: Arthritis; Double-Blind Method; Female; Humans; Male; Middle Aged; Penicillamine; Psoriasis; Random | 1986 |
Effect of antirheumatic agents on the mitogen response of arthritic rat spleen cells.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Arthritis, Rheumatoid; Chloro | 1985 |
Studies of D-penicillamine on strain variability and lymph node cellularity in adjuvant arthritis.
Topics: Animals; Arthritis; Arthritis, Experimental; Cell Division; Edema; Female; Gold Sodium Thiomalate; L | 1985 |
Treating joint inflammation in the elderly: an update.
Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antimalarials; Arthritis; Arthritis, Infectio | 1985 |
Treatment of hemophilic arthritis with D-penicillamine: a preliminary report.
Topics: Animals; Arthritis; Hemarthrosis; Hemophilia A; Humans; Inflammation; Penicillamine; Platelet Aggreg | 1985 |
Proceedings: Suppression of adjuvant arthritis by DL-penicillamine in vitamin B6 deficient rats.
Topics: Adjuvants, Immunologic; Animals; Arthritis; Diet; Penicillamine; Pyridoxine; Rats; Vitamin B 6 Defic | 1974 |
Lysosomal enzyme activity in rats with adjuvant-induced arthritis.
Topics: Acid Phosphatase; Adjuvants, Immunologic; Animals; Arthritis; Female; Forelimb; Glucuronidase; Glyco | 1970 |
[Urinary hydroxyproline excretion in rheumatic conditions and under antirheumatic treatment].
Topics: Adjuvants, Immunologic; Adrenal Cortex Hormones; Animals; Arthritis; Aspirin; Drug Interactions; Glu | 1973 |
[Immunosuppressive therapy in polyarthritis].
Topics: Arthritis; Humans; Immunosuppressive Agents; Long-Term Care; Penicillamine | 1972 |
Failure of oral D-penicillamine to modify adjuvant arthritis or immune response in the rat.
Topics: Administration, Oral; Animals; Antibody Formation; Arthritis; Body Weight; Disease Models, Animal; F | 1972 |
The role of sulfhydryl groups in three models of inflammatory disease.
Topics: Animals; Arthritis; Carrageenan; Croton Oil; Cyclophosphamide; Cysteine; Dexamethasone; Disulfides; | 1973 |
[Penicillamine D and inflammation].
Topics: Adjuvants, Immunologic; Animals; Arthritis; Female; Male; Penicillamine; Rats | 1973 |
Suppression of adjuvant arthritis by penicillamine in pyridoxine deficient rats.
Topics: Animals; Arthritis; Freund's Adjuvant; Male; Penicillamine; Rats; Vitamin B 6 Deficiency | 1974 |
[Modern conception of a causal management of chronic polyarthritis].
Topics: Antigen-Antibody Complex; Arthritis; Chloroquine; Chronic Disease; Gold; Humans; Immunosuppressive A | 1969 |
Effects of oral cysteine, penicillamine and N-acetyl-penicillamine on adjuvant arthritis in rats.
Topics: Adjuvants, Immunologic; Animals; Arthritis; Cysteine; Male; Mycobacterium; Penicillamine; Pyridoxine | 1968 |
Evans blue-carrageenan pleural effusion as a model for the assay of nonsteroidal antirheumatic drugs.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Carrageenan; Chloroquine; Coloring Agents; Ed | 1969 |