Page last updated: 2024-11-07

penicillamine and Pleural Effusion

penicillamine has been researched along with Pleural Effusion in 5 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.

Research Excerpts

ExcerptRelevanceReference
"This case report illustrates the occurrence of a large pleural effusion associated with long-term D-penicillamine therapy."7.69Pleural effusion associated with D-penicillamine therapy: a case report. ( Karkos, C; Manche, A; Moore, A; Thorpe, JA, 1996)
"This case report illustrates the occurrence of a large pleural effusion associated with long-term D-penicillamine therapy."3.69Pleural effusion associated with D-penicillamine therapy: a case report. ( Karkos, C; Manche, A; Moore, A; Thorpe, JA, 1996)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kahan, BC1
Morris, TP1
Huggins, JT1
Sahn, SA1
Karkos, C1
Moore, A1
Manche, A1
Thorpe, JA1
White, JP1
Ward, MJ1
Sancilio, LF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized Controlled Trial To Assess Risk of Delirium in Older Adults Undergoing Hip Fracture Surgery With Spinal or General Anesthesia[NCT02190903]15 participants (Actual)Interventional2013-10-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Postoperative Delirium After Hip Fracture Surgery

Delirium will be assessed by the Confusion Assessment Method Instrument (CAM), a validated method of assessing delirium based on the presence of both (1) an acute onset of signs and symptoms with a fluctuating course AND (2) inattention; PLUS (3) disorganized thinking OR (4) an altered level of consciousness. (NCT02190903)
Timeframe: Up to 5 days post hip fracture surgery

InterventionParticipants (Count of Participants)
General Endotracheal Anesthesia2
Regional (Spinal) Anesthesia0

Reviews

2 reviews available for penicillamine and Pleural Effusion

ArticleYear
Drug-induced pleural disease.
    Clinics in chest medicine, 2004, Volume: 25, Issue:1

    Topics: Anti-Infective Agents, Urinary; Antimetabolites, Antineoplastic; Bleomycin; Cardiovascular Agents; C

2004
Drug-induced adverse pulmonary reactions.
    Adverse drug reactions and acute poisoning reviews, 1985,Winter, Volume: 4, Issue:4

    Topics: Amiodarone; Asthma; Bleomycin; Carmustine; Drug-Related Side Effects and Adverse Reactions; Gold; Hu

1985

Other Studies

3 other studies available for penicillamine and Pleural Effusion

ArticleYear
Improper analysis of trials randomised using stratified blocks or minimisation.
    Statistics in medicine, 2012, Feb-20, Volume: 31, Issue:4

    Topics: Antineoplastic Agents; Back Injuries; Bias; Breast Neoplasms; Carcinoma; Computer Simulation; Data I

2012
Pleural effusion associated with D-penicillamine therapy: a case report.
    Journal of clinical pharmacy and therapeutics, 1996, Volume: 21, Issue:1

    Topics: Adult; Antidotes; Drainage; Female; Hepatolenticular Degeneration; Humans; Penicillamine; Pleural Ef

1996
Evans blue-carrageenan pleural effusion as a model for the assay of nonsteroidal antirheumatic drugs.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 168, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Carrageenan; Chloroquine; Coloring Agents; Ed

1969