penicillamine has been researched along with Pancreatic Neoplasms in 7 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pancreatic ductal carcinoma is characterized by a profound chemoresistance." | 1.32 | Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta. ( Arlt, A; Fölsch, UR; Kalthoff, H; Klöppel, G; Kruse, ML; Müerköster, S; Schäfer, H; Sebens, T; Sipos, B; Wegehenkel, K; Witt, M, 2004) |
| ""Autoimmune" hypoglycemia is a syndrome consisting of fasting hypoglycemia, hyperinsulinemia, and insulin-binding antibodies in a patient who has never been exposed to exogenous insulin." | 1.27 | Insulin autoimmunity as a cause of hypoglycemia. ( Benson, EA; Fredlund, PN; Ho, P; Wang, C; Wu, PC; Yueng, RT, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chae, SY | 1 |
| Lee, M | 1 |
| Kim, SW | 1 |
| Bae, YH | 1 |
| Müerköster, S | 1 |
| Wegehenkel, K | 1 |
| Arlt, A | 1 |
| Witt, M | 1 |
| Sipos, B | 1 |
| Kruse, ML | 1 |
| Sebens, T | 1 |
| Klöppel, G | 1 |
| Kalthoff, H | 1 |
| Fölsch, UR | 1 |
| Schäfer, H | 1 |
| Kwon, KB | 1 |
| Kim, EK | 1 |
| Lim, JG | 1 |
| Shin, BC | 1 |
| Han, SC | 1 |
| Song, BK | 1 |
| Kim, KS | 1 |
| Seo, EA | 1 |
| Ryu, DG | 1 |
| Benson, EA | 1 |
| Ho, P | 1 |
| Wang, C | 1 |
| Wu, PC | 1 |
| Fredlund, PN | 1 |
| Yueng, RT | 1 |
| Kaneto, H | 1 |
| Fujii, J | 1 |
| Seo, HG | 1 |
| Suzuki, K | 1 |
| Matsuoka, T | 1 |
| Nakamura, M | 1 |
| Tatsumi, H | 1 |
| Yamasaki, Y | 1 |
| Kamada, T | 1 |
| Taniguchi, N | 1 |
| Grassi, C | 1 |
| D'Ascenzo, M | 1 |
| Valente, A | 1 |
| Battista Azzena, G | 1 |
| Nakata, M | 1 |
| Uto, N | 1 |
| Maruyama, I | 1 |
| Yada, T | 1 |
7 other studies available for penicillamine and Pancreatic Neoplasms
| Article | Year |
|---|---|
Protection of insulin secreting cells from nitric oxide induced cellular damage by crosslinked hemoglobin.
Topics: Animals; Cell Line, Tumor; Cell Survival; Cells, Cultured; Coated Materials, Biocompatible; Cross-Li | 2004 |
Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta.
Topics: Adenocarcinoma; Carcinoma, Pancreatic Ductal; Cell Communication; Cell Line, Tumor; Drug Resistance, | 2004 |
Protective effect of Coptidis Rhizoma on S-nitroso-N-acetylpenicillamine (SNAP)-induced apoptosis and necrosis in pancreatic RINm5F cells.
Topics: Animals; Apoptosis; Cell Line, Tumor; Coptis chinensis; Dose-Response Relationship, Drug; Drugs, Chi | 2005 |
Insulin autoimmunity as a cause of hypoglycemia.
Topics: Autoantibodies; Diagnosis, Differential; Female; Humans; Hyperplasia; Hypoglycemia; Insulin Antibodi | 1984 |
Apoptotic cell death triggered by nitric oxide in pancreatic beta-cells.
Topics: Amino Acid Oxidoreductases; Animals; Apoptosis; Cell Survival; Cricetinae; Cycloheximide; Dactinomyc | 1995 |
Ca2+ channel inhibition induced by nitric oxide in rat insulinoma RINm5F cells.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Cyclic GMP; Electrophysiology; Enzyme Inhibitor | 1999 |
Nitric oxide induces apoptosis via Ca2+-dependent processes in the pancreatic beta-cell line MIN6.
Topics: Animals; Apoptosis; Calcium; Cell Survival; Chelating Agents; Diabetes Mellitus, Type 1; Egtazic Aci | 1999 |