penicillamine has been researched along with Optic Neuritis in 7 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Optic Neuritis: Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a 53-year-old woman an acute allergic thrombocytopenia (acute Werlhf's disease) occurred after treatment with D-penicillamine for one month which led to death." | 3.65 | [Severe side-effects of treatment with D-penicillamine (author's transl)]. ( Hennemann, HH; Hubertus, H; Stocker, WG, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| TU, J | 1 |
| BLACKWELL, RQ | 1 |
| LEE, PF | 1 |
| Yolton, DP | 1 |
| Hennemann, HH | 1 |
| Hubertus, H | 1 |
| Stocker, WG | 1 |
| Walshe, JM | 1 |
| Leibold, JE | 1 |
| Damaske, E | 1 |
| Althoff, W | 1 |
| Baghdassarian, SA | 1 |
1 review available for penicillamine and Optic Neuritis
| Article | Year |
|---|---|
Drugs having a toxic effect on the optic nerve.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Infective Agents; Contraceptives, Oral; Digitalis G | 1971 |
6 other studies available for penicillamine and Optic Neuritis
| Article | Year |
|---|---|
DL-penicillamine as a cause of optic axial neuritis.
Topics: Chelating Agents; Humans; Neuritis; Optic Neuritis; Penicillamine; Vitamin B 6 Deficiency | 1963 |
Nutritional effects of zinc on ocular and systemic physiology.
Topics: Clioquinol; Dithizone; Ethambutol; Eye Diseases; Humans; Intraocular Pressure; Iodoquinol; Isoniazid | 1981 |
[Severe side-effects of treatment with D-penicillamine (author's transl)].
Topics: Acute Disease; Adult; Arthritis, Rheumatoid; Drug Hypersensitivity; Female; Humans; Male; Middle Age | 1975 |
Chirality of penicillamine.
Topics: Chemistry, Pharmaceutical; Humans; Isomerism; Optic Neuritis; Penicillamine | 1992 |
[Optic neuritis in a child with Wilson's disease].
Topics: Adolescent; Copper; Hepatolenticular Degeneration; Humans; Long-Term Care; Male; Optic Atrophy; Opti | 1972 |
Optic neuropathy due to lead poisoning. Report of a case.
Topics: Environmental Exposure; Eye Diseases; Humans; Lead Poisoning; Male; Middle Aged; Occupational Diseas | 1968 |