penicillamine has been researched along with Optic Nerve Diseases in 2 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Optic Nerve Diseases: Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Optic neuropathy developed in a patient with rheumatoid arthritis who had been receiving D-penicillamine for about 1 year." | 7.67 | Optic neuropathy associated with penicillamine therapy in a patient with rheumatoid arthritis. ( Burde, RM; Klingele, TG, 1984) |
| "Optic neuropathy developed in a patient with rheumatoid arthritis who had been receiving D-penicillamine for about 1 year." | 3.67 | Optic neuropathy associated with penicillamine therapy in a patient with rheumatoid arthritis. ( Burde, RM; Klingele, TG, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Klingele, TG | 1 |
| Burde, RM | 1 |
| Lee, AH | 1 |
| Lawton, NF | 1 |
2 other studies available for penicillamine and Optic Nerve Diseases
| Article | Year |
|---|---|
Optic neuropathy associated with penicillamine therapy in a patient with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Fluorescein Angiography; Humans; Male; Middle Aged; Optic Nerve Diseases; Pap | 1984 |
Penicillamine treatment of Wilson's disease and optic neuropathy.
Topics: Adult; Color Perception; Dose-Response Relationship, Drug; Female; Hepatolenticular Degeneration; Hu | 1991 |