penicillamine has been researched along with Muscular Dystrophies in 6 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Muscular Dystrophies: A heterogeneous group of inherited MYOPATHIES, characterized by wasting and weakness of the SKELETAL MUSCLE. They are categorized by the sites of MUSCLE WEAKNESS; AGE OF ONSET; and INHERITANCE PATTERNS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind controlled trial of penicillamine and vitamin E against placebo was conducted in 106 boys with Duchenne muscular dystrophy." | 9.06 | Clinical investigation in Duchenne muscular dystrophy: penicillamine and vitamin E. ( Brooke, MH; Fenichel, GM; Florence, J; Griggs, RC; Kaiser, KK; Mendell, JR; Miller, JP; Moxley, RT; Park, JH; Provine, MA, 1988) |
| "No effect of penicillamine upon intelligence was found in boys with Duchenne muscular dystrophy when compared to placebo administered in a double-blind fashion." | 9.05 | Intellectual function in Duchenne muscular dystrophy: the influence of penicillamine. ( Buchanan, DC; Roelofs, RI; Saavedra de Arango, G; White, DK, 1981) |
| "Eleven boys with Duchenne's muscular dystrophy, randomly assigned to placebo (group A, n = 6) or penicillamine treatment (group B, n = 5), received three capsules per day containing lactose or 250 mg of penicillamine." | 9.04 | Treatment of Duchenne's muscular dystrophy with penicillamine. Results of a double-blind trial. ( Buchanan, DC; de Arango, GS; Kinsman, D; Law, PK; Park, JH; Roelofs, RI, 1979) |
| "A double-blind controlled trial of penicillamine and vitamin E against placebo was conducted in 106 boys with Duchenne muscular dystrophy." | 5.06 | Clinical investigation in Duchenne muscular dystrophy: penicillamine and vitamin E. ( Brooke, MH; Fenichel, GM; Florence, J; Griggs, RC; Kaiser, KK; Mendell, JR; Miller, JP; Moxley, RT; Park, JH; Provine, MA, 1988) |
| "No effect of penicillamine upon intelligence was found in boys with Duchenne muscular dystrophy when compared to placebo administered in a double-blind fashion." | 5.05 | Intellectual function in Duchenne muscular dystrophy: the influence of penicillamine. ( Buchanan, DC; Roelofs, RI; Saavedra de Arango, G; White, DK, 1981) |
| "Eleven boys with Duchenne's muscular dystrophy, randomly assigned to placebo (group A, n = 6) or penicillamine treatment (group B, n = 5), received three capsules per day containing lactose or 250 mg of penicillamine." | 5.04 | Treatment of Duchenne's muscular dystrophy with penicillamine. Results of a double-blind trial. ( Buchanan, DC; de Arango, GS; Kinsman, D; Law, PK; Park, JH; Roelofs, RI, 1979) |
| " A patient and his young sister were shown to be suffering from spinal muscular atrophy with superimposed, excessive proliferative activity of fibroblasts, and in these cases a beneficial effect of penicillamine was demonstrated." | 3.65 | The syndrome of myosclerosis. ( Bradley, WG; Gardner-Medwin, D; Hudgson, P; Walton, JN, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kean, WF | 1 |
| Bellamy, N | 1 |
| Lock, CJ | 1 |
| Adachi, J | 1 |
| Buchanan, DC | 2 |
| Roelofs, RI | 2 |
| White, DK | 1 |
| Saavedra de Arango, G | 1 |
| de Arango, GS | 1 |
| Law, PK | 1 |
| Kinsman, D | 1 |
| Park, JH | 2 |
| Morgan, J | 1 |
| Cohen, L | 1 |
| Bittner, S | 1 |
| Bozyk, ME | 1 |
| Fenichel, GM | 1 |
| Brooke, MH | 1 |
| Griggs, RC | 1 |
| Mendell, JR | 1 |
| Miller, JP | 1 |
| Moxley, RT | 1 |
| Provine, MA | 1 |
| Florence, J | 1 |
| Kaiser, KK | 1 |
| Bradley, WG | 1 |
| Hudgson, P | 1 |
| Gardner-Medwin, D | 1 |
| Walton, JN | 1 |
3 trials available for penicillamine and Muscular Dystrophies
| Article | Year |
|---|---|
Intellectual function in Duchenne muscular dystrophy: the influence of penicillamine.
Topics: Adolescent; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Humans; Intellig | 1981 |
Treatment of Duchenne's muscular dystrophy with penicillamine. Results of a double-blind trial.
Topics: Age Factors; Child; Child, Preschool; Clinical Trials as Topic; Creatine Kinase; Double-Blind Method | 1979 |
Clinical investigation in Duchenne muscular dystrophy: penicillamine and vitamin E.
Topics: Child; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Electromyography; H | 1988 |
3 other studies available for penicillamine and Muscular Dystrophies
| Article | Year |
|---|---|
Bio-inorganic effects of D-penicillamine in children and in the elderly.
Topics: Abnormalities, Drug-Induced; Aged; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Cystinuria; Fe | 1984 |
Penicillamine effects on enzyme efflux from skeletal and heart muscle.
Topics: Animals; Body Weight; Creatine Kinase; Heart; Humans; L-Lactate Dehydrogenase; Male; Mice; Muscles; | 1977 |
The syndrome of myosclerosis.
Topics: Adult; Child; Child, Preschool; Collagen; Diagnosis, Differential; Electromyography; Female; Humans; | 1973 |