penicillamine has been researched along with Muscle Contraction in 49 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Two patients with classical rheumatoid arthritis developed myopathy during treatment with penicillamine." | 7.66 | Penicillamine-induced polymyositis-dermatomyositis. ( Halberg, P; Højgaard, K; Lyon, BB; Petersen, J; Ullman, S, 1978) |
| " In thoracic aortic rings from CH rats, cumulative dose-response curves to phenylephrine (PE) in the presence of the nitric oxide (NO) synthase inhibitor Nomega-nitro-L-arginine (L-NNA) and the HO inhibitor zinc protoporphyrin 9 (ZnPPIX) elicited increased contractility compared with CH rings treated with only L-NNA." | 5.30 | Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia. ( Caudill, TK; Kanagy, NL; Resta, TC; Walker, BR, 1998) |
| "The role of muscle contraction, prostanoids, nitric oxide and adenosine in the regulation of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF) and endothelial cell proliferative compounds in skeletal muscle cell cultures was examined." | 3.72 | Regulation of VEGF and bFGF mRNA expression and other proliferative compounds in skeletal muscle cells. ( Hellsten, Y; Jensen, L; Schjerling, P, 2004) |
| "Two patients with classical rheumatoid arthritis developed myopathy during treatment with penicillamine." | 3.66 | Penicillamine-induced polymyositis-dermatomyositis. ( Halberg, P; Højgaard, K; Lyon, BB; Petersen, J; Ullman, S, 1978) |
| " Endothelial dysfunction and poor NO bioavailability are hallmarks of vasculature dysfunction in states of insulin resistance and metabolic syndrome (MetSyn)." | 1.43 | Blunted flow-mediated responses and diminished nitric oxide synthase expression in lymphatic thoracic ducts of a rat model of metabolic syndrome. ( Gasheva, O; Muthuchamy, M; Zawieja, DC; Zawieja, SD, 2016) |
| "Cromakalim dilation was attenuated by ET-1 and partially restored by the protein kinase C (PKC) inhibitor staurosporine (12 +/- 1 and 28 +/- 1 vs." | 1.30 | Endothelin impairs ATP-sensitive K+ channel function after brain injury. ( Armstead, WM; Kasemsri, T, 1997) |
| " In thoracic aortic rings from CH rats, cumulative dose-response curves to phenylephrine (PE) in the presence of the nitric oxide (NO) synthase inhibitor Nomega-nitro-L-arginine (L-NNA) and the HO inhibitor zinc protoporphyrin 9 (ZnPPIX) elicited increased contractility compared with CH rings treated with only L-NNA." | 1.30 | Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia. ( Caudill, TK; Kanagy, NL; Resta, TC; Walker, BR, 1998) |
| "Twenty-three patients with Wilson's disease (WD) treated with D-penicillamine underwent clinical examination, as well as laboratory and motor testing." | 1.29 | Motor impairment in Wilson's disease, I: Slowness of voluntary limb movements. ( Arendt, G; Freund, HJ; Hefter, H; Stremmel, W, 1993) |
| "When carbachol was added to the chamber, the electrode responded when the solution was bubbled with 20% but not with 40% or 95% of oxygen, suggesting a much faster decomposition of nitric oxide in the presence of higher concentrations of oxygen." | 1.29 | A nitric oxide-sensitive electrode: requirement of lower oxygen concentration for detecting nitric oxide from the tissue. ( Fukushima, S; Hashimoto, M; Ishida, Y; Isokawa, S; Masumura, S; Momose, K; Murakami, E; Nakayama, K; Sasaki, T; Tamura, K, 1996) |
| " With vitamin E as adjunct therapy, the dosage level of penicillamine could be lowered by 50%, thereby minimizing side effects." | 1.27 | Interactions of vitamin E and penicillamine in the treatment of hereditary avian muscular dystrophy. ( Brandon, S; Dement, SH; Hill, EJ; Park, CR; Park, JH; Serafin, WE, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (20.41) | 18.7374 |
| 1990's | 29 (59.18) | 18.2507 |
| 2000's | 9 (18.37) | 29.6817 |
| 2010's | 1 (2.04) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zawieja, SD | 1 |
| Gasheva, O | 1 |
| Zawieja, DC | 1 |
| Muthuchamy, M | 1 |
| Jensen, L | 1 |
| Schjerling, P | 1 |
| Hellsten, Y | 1 |
| Goy, MF | 1 |
| Chan, WY | 1 |
| Fear, R | 1 |
| Du Vigneaud, V | 3 |
| Ignarro, LJ | 1 |
| Burke, TM | 1 |
| Wood, KS | 1 |
| Wolin, MS | 1 |
| Kadowitz, PJ | 1 |
| Pearce, WJ | 3 |
| White, CR | 1 |
| Kojda, G | 1 |
| Beck, JK | 1 |
| Meyer, W | 1 |
| Noack, E | 1 |
| Folkerts, G | 2 |
| van der Linde, HJ | 2 |
| Nijkamp, FP | 2 |
| Dubey, RK | 1 |
| Hefter, H | 2 |
| Arendt, G | 2 |
| Stremmel, W | 2 |
| Freund, HJ | 2 |
| Ishida, Y | 1 |
| Hashimoto, M | 1 |
| Fukushima, S | 1 |
| Masumura, S | 1 |
| Sasaki, T | 1 |
| Nakayama, K | 1 |
| Tamura, K | 1 |
| Murakami, E | 1 |
| Isokawa, S | 1 |
| Momose, K | 1 |
| Sadeghi-Hashjin, G | 1 |
| Henricks, PA | 1 |
| Verheyen, AK | 1 |
| De la Lande, IS | 1 |
| Stafford, I | 1 |
| Horowitz, JD | 1 |
| Keef, KD | 1 |
| Murray, DC | 1 |
| Sanders, KM | 1 |
| Smith, TK | 2 |
| Galler, S | 1 |
| Hilber, K | 1 |
| Göbesberger, A | 1 |
| Carrier, GO | 1 |
| Fuchs, LC | 1 |
| Winecoff, AP | 1 |
| Giulumian, AD | 1 |
| White, RE | 1 |
| Murrant, CL | 1 |
| Frisbee, JC | 1 |
| Barclay, JK | 1 |
| Kasemsri, T | 1 |
| Armstead, WM | 1 |
| Baba, K | 1 |
| Yoshida, K | 1 |
| Hattori, T | 1 |
| Kobayashi, T | 1 |
| McKendrick, JD | 1 |
| Salas, E | 1 |
| Dubé, GP | 1 |
| Murat, J | 1 |
| Russell, JC | 1 |
| Radomski, MW | 1 |
| Grieve, DJ | 1 |
| Avella, MA | 1 |
| Botham, KM | 1 |
| Elliott, J | 1 |
| Caudill, TK | 1 |
| Resta, TC | 1 |
| Kanagy, NL | 1 |
| Walker, BR | 1 |
| McCarron, SL | 1 |
| Maréchal, G | 1 |
| Beckers-Bleukx, G | 1 |
| Billack, B | 1 |
| Laskin, JD | 1 |
| Heck, PT | 1 |
| Troll, W | 1 |
| Gallo, MA | 1 |
| Heck, DE | 1 |
| Régrigny, O | 1 |
| Delagrange, P | 1 |
| Scalbert, E | 1 |
| Lartaud-Idjouadiene, I | 1 |
| Atkinson, J | 1 |
| Chillon, JM | 1 |
| Fujisawa, K | 1 |
| Onoue, H | 1 |
| Abe, K | 1 |
| Ito, Y | 1 |
| Ghisdal, P | 1 |
| Godfraind, T | 1 |
| Morel, N | 1 |
| Takano, H | 1 |
| Tang, XL | 1 |
| Kodani, E | 1 |
| Bolli, R | 1 |
| Alloatti, G | 1 |
| Penna, C | 1 |
| Mariano, F | 1 |
| Camussi, G | 1 |
| Hennan, JK | 1 |
| Diamond, J | 1 |
| Andrew, PS | 1 |
| Deng, Y | 1 |
| Sultanian, R | 1 |
| Kaufman, S | 1 |
| Queiroz, RN | 1 |
| Alves-Do-Prado, W | 1 |
| Moon, A | 1 |
| Tazi, KA | 1 |
| Barrière, E | 1 |
| Moreau, R | 1 |
| Poirel, O | 1 |
| Lebrec, D | 1 |
| Petersen, J | 1 |
| Halberg, P | 1 |
| Højgaard, K | 1 |
| Lyon, BB | 1 |
| Ullman, S | 1 |
| Webster, DD | 1 |
| Mortimer, JA | 1 |
| Flitney, FW | 1 |
| Megson, IL | 1 |
| Flitney, DE | 1 |
| Butler, AR | 1 |
| Meyer, BU | 1 |
| Britton, TC | 1 |
| Bischoff, C | 1 |
| Machetanz, J | 1 |
| Benecke, R | 1 |
| Conrad, B | 1 |
| Hull, AD | 2 |
| Long, DM | 2 |
| Longo, LD | 2 |
| Berardelli, A | 1 |
| Inghilleri, M | 1 |
| Priori, A | 1 |
| Thompson, PD | 1 |
| Fabri, S | 1 |
| Fieschi, C | 1 |
| Manfredi, M | 1 |
| Serafin, WE | 1 |
| Dement, SH | 1 |
| Brandon, S | 1 |
| Hill, EJ | 1 |
| Park, CR | 1 |
| Park, JH | 1 |
| Verzár, F | 1 |
| Moser, P | 1 |
| Vargaftig, BB | 1 |
| Tranier, Y | 1 |
| Chignard, M | 1 |
| Vavrek, RJ | 1 |
| Ferger, MF | 1 |
| Allen, GA | 1 |
| Rich, DH | 1 |
| Blomquist, AT | 1 |
| Gascon, AL | 1 |
| Schulz, H | 1 |
1 review available for penicillamine and Muscle Contraction
| Article | Year |
|---|---|
Nitric oxide: an inhibitory retrograde modulator in the crustacean heart.
Topics: Animals; Cyclic GMP; Decapoda; Heart; Heart Conduction System; Immunoblotting; Models, Biological; M | 2005 |
48 other studies available for penicillamine and Muscle Contraction
| Article | Year |
|---|---|
Blunted flow-mediated responses and diminished nitric oxide synthase expression in lymphatic thoracic ducts of a rat model of metabolic syndrome.
Topics: Animals; Antioxidants; Cyclic N-Oxides; Endothelium, Lymphatic; Enzyme Inhibitors; Male; Metabolic S | 2016 |
Regulation of VEGF and bFGF mRNA expression and other proliferative compounds in skeletal muscle cells.
Topics: Adenosine; Adenosine Diphosphate; Animals; Cell Proliferation; Cells, Cultured; Electric Stimulation | 2004 |
Some pharmacologic studies on 1-L-penicillamine-oxytocin and 1-deaminopenicillamine-oxytocin: two potent oxytocin inhibitors.
Topics: Animals; Biological Assay; Female; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Organ Si | 1967 |
Association between cyclic GMP accumulation and acetylcholine-elicited relaxation of bovine intrapulmonary artery.
Topics: Acetylcholine; Animals; Cattle; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endotheliu | 1984 |
Determination of the cyclic GMP concentration yielding half-maximal activation of cyclic GMP-dependent protein kinase in intact ovine basilar arteries.
Topics: Animals; Basilar Artery; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Female | 1995 |
Nitrovasodilator-induced relaxation and tolerance development in porcine vena cordis magna: dependence on intact endothelium.
Topics: Animals; Arginine; Cysteine; Dinoprost; Drug Tolerance; Endothelium, Vascular; In Vitro Techniques; | 1994 |
Virus-induced airway hyperresponsiveness in guinea pigs is related to a deficiency in nitric oxide.
Topics: Animals; Arginine; Bronchoconstriction; Guinea Pigs; Histamine; Hypersensitivity; In Vitro Technique | 1995 |
Vasodilator-derived nitric oxide inhibits fetal calf serum- and angiotensin-II-induced growth of renal arteriolar smooth muscle cells.
Topics: Angiotensin II; Animals; Arterioles; Cattle; Cell Count; Cell Division; Cells, Cultured; Cyclic GMP; | 1994 |
Motor impairment in Wilson's disease, I: Slowness of voluntary limb movements.
Topics: Adolescent; Adult; Basal Ganglia; Female; Hepatolenticular Degeneration; Humans; Isometric Contracti | 1993 |
Motor impairment in Wilson's disease, II: Slowness of speech.
Topics: Adolescent; Adult; Basal Ganglia; Female; Hepatolenticular Degeneration; Humans; Liver Transplantati | 1993 |
A nitric oxide-sensitive electrode: requirement of lower oxygen concentration for detecting nitric oxide from the tissue.
Topics: Animals; Aorta, Thoracic; Arginine; Carbachol; Electrodes; Guinea Pigs; Male; Muscle Contraction; Mu | 1996 |
Bovine tracheal responsiveness in vitro: role of the epithelium and nitric oxide.
Topics: Animals; Cattle; Dinoprostone; Epithelium; Female; Histamine; In Vitro Techniques; Male; Muscle Cont | 1996 |
Heterogeneity of glyceryl trinitrate response in isolated bovine coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Bradykinin; Cattle; Cor | 1996 |
Basal release of nitric oxide induces an oscillatory motor pattern in canine colon.
Topics: Animals; Colon; Dogs; Enzyme Inhibitors; Female; Male; Membrane Potentials; Muscle Contraction; Myen | 1997 |
Effects of nitric oxide on force-generating proteins of skeletal muscle.
Topics: Adenosine Triphosphatases; Animals; Calcium; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Muscl | 1997 |
Nitrovasodilators relax mesenteric microvessels by cGMP-induced stimulation of Ca-activated K channels.
Topics: Animals; Cells, Cultured; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; In Vitro Techniques; Kin | 1997 |
The effect of nitric oxide and endothelin on skeletal muscle contractility changes when stimulation is altered.
Topics: Animals; Dogs; Endothelin-1; Female; Male; Mice; Muscle Contraction; Muscle, Skeletal; Nitric Oxide; | 1997 |
Endothelin impairs ATP-sensitive K+ channel function after brain injury.
Topics: Animals; Animals, Newborn; Arterioles; Brain Injuries; Calcitonin Gene-Related Peptide; Cerebral Art | 1997 |
Effects of prostaglandin E2 on nitric oxide-mediated nonadrenergic noncholinergic relaxations in the guinea-pig tracheal muscle.
Topics: Animals; Autonomic Nervous System; Dinoprostone; Electric Stimulation; Enzyme Inhibitors; Guinea Pig | 1998 |
Inhibition of nitric oxide generation unmasks vascular dysfunction in insulin-resistant, obese JCR:LA-cp rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Platelets; Blood Pressure; Cyclic GMP; Diabetes Melli | 1998 |
Effects of chylomicrons and chylomicron remnants on endothelium-dependent relaxation of rat aorta.
Topics: Adenosine Triphosphate; Animals; Aorta; Calcimycin; Carbachol; Chylomicrons; Dose-Response Relations | 1998 |
Role of endothelial carbon monoxide in attenuated vasoreactivity following chronic hypoxia.
Topics: Animals; Aorta, Thoracic; Arsenites; Carbon Monoxide; Endothelium, Vascular; Enzyme Inhibitors; Guan | 1998 |
Nitric oxide modulates cholinergic reflex pathways to the longitudinal and circular muscle in the isolated guinea-pig distal colon.
Topics: Animals; Autonomic Pathways; Colon; Electric Stimulation; Enzyme Inhibitors; Guanylate Cyclase; Guin | 1998 |
Effect of nitric oxide on the maximal velocity of shortening of a mouse skeletal muscle.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Biomechanical Phenomena; Cyclic GMP; Enzyme I | 1998 |
Alterations in cholinergic signaling modulate contraction of isolated sea urchin tube feet: potential role of nitric oxide.
Topics: Acetylcholine; Animals; Enzyme Inhibitors; Muscle Contraction; Muscle, Smooth; NG-Nitroarginine Meth | 1998 |
Effects of melatonin on rat pial arteriolar diameter in vivo.
Topics: Algorithms; Animals; Antioxidants; Arterioles; Benzimidazoles; Dose-Response Relationship, Drug; Enz | 1999 |
Multiple calcium channels regulate neurotransmitter release from vagus nerve terminals in the cat bronchiole.
Topics: Acetylcholine; Animals; Bronchi; Cadmium; Calcium Channel Blockers; Calcium Channels; Cats; Electric | 1999 |
Effect of nitro-L-arginine on electrical and mechanical responses to acetylcholine in the superior mesenteric artery from stroke-prone hypertensive rat.
Topics: Acetylcholine; Animals; Drug Combinations; Enzyme Inhibitors; In Vitro Techniques; Male; Membrane Po | 1999 |
Late preconditioning enhances recovery of myocardial function after infarction in conscious rabbits.
Topics: Animals; Consciousness; Dobutamine; Dose-Response Relationship, Drug; Electrocardiography; Hemodynam | 2000 |
Role of NO and PAF in the impairment of skeletal muscle contractility induced by TNF-alpha.
Topics: Animals; Azepines; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Skeletal; NG-Nitroa | 2000 |
Effect of NO donors on protein phosphorylation in intact vascular and nonvascular smooth muscles.
Topics: Animals; Aorta, Thoracic; Atrial Natriuretic Factor; Cyclic GMP; Cyclic GMP-Dependent Protein Kinase | 2001 |
Nitric oxide increases fluid extravasation from the splenic circulation of the rat.
Topics: Animals; Arteries; Hematocrit; In Vitro Techniques; Infusions, Parenteral; Male; Muscle Contraction; | 2001 |
Effects of L-arginine on the diaphragm muscle twitches elicited at different frequencies of nerve stimulation.
Topics: Acetylcholine; Animals; Arginine; Diaphragm; Electric Stimulation; Free Radical Scavengers; Muscle C | 2001 |
Influence of nitric oxide signalling pathways on pre-contracted human detrusor smooth muscle in vitro.
Topics: Dose-Response Relationship, Drug; Evoked Potentials; Humans; Muscle Contraction; Muscle Relaxation; | 2002 |
Relationship between protein kinase C alterations and nitric oxide overproduction in cirrhotic rat aortas.
Topics: Animals; Aorta, Thoracic; Down-Regulation; Enzyme Inhibitors; In Vitro Techniques; Liver Cirrhosis, | 2002 |
Penicillamine-induced polymyositis-dermatomyositis.
Topics: Action Potentials; Arthritis, Rheumatoid; Dermatomyositis; Female; Humans; Middle Aged; Muscle Contr | 1978 |
Failure of L-dopa to relieve activated rigidity in Parkinson's disease.
Topics: Adult; Amantadine; Extrapyramidal Tracts; Hepatolenticular Degeneration; Humans; Levodopa; Male; Mid | 1977 |
Iron-sulphur cluster nitrosyls, a novel class of nitric oxide generator: mechanism of vasodilator action on rat isolated tail artery.
Topics: Animals; Arteries; Carbachol; Chemical Phenomena; Chemistry, Physical; In Vitro Techniques; Iron Che | 1992 |
Abnormal conduction in corticospinal pathways in Wilson's disease: investigation of nine cases with magnetic brain stimulation.
Topics: Adult; Electromagnetic Fields; Electromyography; Follow-Up Studies; Hepatolenticular Degeneration; H | 1991 |
Chronic hypoxia alters ovine cerebrovascular reactivity and composition.
Topics: Animals; Cerebrovascular Circulation; Chronic Disease; Endothelium, Vascular; Hypoxia; In Vitro Tech | 1991 |
Pregnancy-induced changes in ovine cerebrovascular reactivity and composition.
Topics: Animals; Body Water; Calcimycin; Cerebrovascular Circulation; Female; Muscle Contraction; Muscle, Sm | 1991 |
Involvement of corticospinal tract in Wilson's disease. A study of three cases with transcranial stimulation.
Topics: Adolescent; Adult; Electric Stimulation; Female; Hepatolenticular Degeneration; Humans; Male; Muscle | 1990 |
Interactions of vitamin E and penicillamine in the treatment of hereditary avian muscular dystrophy.
Topics: alpha-Tocopherol; Animals; Chickens; Creatine Kinase; Dose-Response Relationship, Drug; Double-Blind | 1987 |
Influences on the structural stability of collagen in relation to ageing.
Topics: Aging; Animals; Biomechanical Phenomena; Collagen; Connective Tissue; Cysteine; Drug Interactions; F | 1973 |
Inhibition by sulfhydryl agents of arachidonic acid-induced platelet aggregation and release of potential inflammatory substances.
Topics: Animals; Aorta; Arachidonic Acids; Copper; Depression, Chemical; Dithiothreitol; Glycerol; In Vitro | 1974 |
Synthesis of three oxytocin analogs related to (1-deaminopenicillamine)oxytocin possessing antioxytocic acitvity.
Topics: Acetates; Animals; Chickens; Female; Muscle Contraction; Optical Rotation; Oxytocin; Penicillamine; | 1972 |
Influence of rat plasma and of various cations on the anti-eledoisin activity of morin.
Topics: Acetates; Animals; Blood Pressure; Chelating Agents; Eledoisin; Flavonoids; Muscle Contraction; Musc | 1969 |
Synthesis of 1-L-penicillamine-oxytocin, 1-D-penicillamine-oxytocin, and 1-deaminopenicillamine-oxytocin, potent inhibitors of the oxytocic response of oxytocin.
Topics: Animals; Birds; Chemistry, Organic; Female; Muscle Contraction; Organic Chemistry Phenomena; Oxytoci | 1966 |