penicillamine has been researched along with MS (Multiple Sclerosis) in 8 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-three patients with the chronic progressive or intermittent relapsing form of multiple sclerosis (MS) were treated with d-penicillamine over a period from 6 weeks to 12 months." | 9.04 | Penicillamine in multiple sclerosis. Therapeutic trial and design of uncontrolled pilot drug study. ( Cendrowski, W; Czlonkowska, A, 1976) |
| "A pilot study of the effect of D-penicillamine in multiple sclerosis (MS) was undertaken because of D-penicillamine's activity against RNA neurotropic viruses, because it is effective against the auto-immune disease, rheumatoid arthritis, and because both viruses and autoimmunity have been implicated in multiple sclerosis." | 7.66 | Pilot study of d-penicillamine, vitamins and minerals in multiple sclerosis. ( Alba, A; Berger, AR; Rudez, A; Seelig, MS; Tarlau, M, 1978) |
| "It has been suggested that lead may be a cause of multiple sclerosis, but confirmation of this hypothesis is difficult to obtain as lead is so widely present both in the environment and in many human tissues." | 7.65 | Lead and multiple sclerosis. ( , 1976) |
| "Twenty-three patients with the chronic progressive or intermittent relapsing form of multiple sclerosis (MS) were treated with d-penicillamine over a period from 6 weeks to 12 months." | 5.04 | Penicillamine in multiple sclerosis. Therapeutic trial and design of uncontrolled pilot drug study. ( Cendrowski, W; Czlonkowska, A, 1976) |
| "A pilot study of the effect of D-penicillamine in multiple sclerosis (MS) was undertaken because of D-penicillamine's activity against RNA neurotropic viruses, because it is effective against the auto-immune disease, rheumatoid arthritis, and because both viruses and autoimmunity have been implicated in multiple sclerosis." | 3.66 | Pilot study of d-penicillamine, vitamins and minerals in multiple sclerosis. ( Alba, A; Berger, AR; Rudez, A; Seelig, MS; Tarlau, M, 1978) |
| "It has been suggested that lead may be a cause of multiple sclerosis, but confirmation of this hypothesis is difficult to obtain as lead is so widely present both in the environment and in many human tissues." | 3.65 | Lead and multiple sclerosis. ( , 1976) |
| "The diagnosis of MS preceded that of Wilson's disease and was relatively mild in course." | 2.82 | Rare co-occurrence of multiple sclerosis and Wilson's disease - case report. ( Despotov, K; Klivényi, P; Nagy, I; Pálvölgyi, A; Rajda, C; Vécsei, L, 2022) |
| "Multiple sclerosis is a chronic inflammatory disease of the CNS leading to focal destruction of myelin, still the earliest changes that lead to lesion formation are not known." | 1.32 | Molecular changes in normal appearing white matter in multiple sclerosis are characteristic of neuroprotective mechanisms against hypoxic insult. ( Graumann, U; Reynolds, R; Schaeren-Wiemers, N; Steck, AJ, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Despotov, K | 1 |
| Klivényi, P | 1 |
| Nagy, I | 1 |
| Pálvölgyi, A | 1 |
| Vécsei, L | 1 |
| Rajda, C | 1 |
| Graumann, U | 1 |
| Reynolds, R | 1 |
| Steck, AJ | 1 |
| Schaeren-Wiemers, N | 1 |
| Norga, K | 1 |
| Paemen, L | 1 |
| Masure, S | 1 |
| Dillen, C | 1 |
| Heremans, H | 1 |
| Billiau, A | 1 |
| Carton, H | 2 |
| Cuzner, L | 1 |
| Olsson, T | 1 |
| Van Damme, J | 1 |
| Dubois, B | 1 |
| D'Hooghe, MB | 1 |
| De Lepeleire, K | 1 |
| Ketelaer, P | 1 |
| Opdenakker, G | 1 |
| Lodemann, E | 1 |
| Seelig, MS | 1 |
| Alba, A | 1 |
| Berger, AR | 1 |
| Rudez, A | 1 |
| Tarlau, M | 1 |
| Cendrowski, W | 1 |
| Czlonkowska, A | 1 |
1 review available for penicillamine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Rare co-occurrence of multiple sclerosis and Wilson's disease - case report.
Topics: Copper; Hepatolenticular Degeneration; Humans; Multiple Sclerosis; Penicillamine; Quality of Life | 2022 |
2 trials available for penicillamine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Toxicity in a double-blind, placebo-controlled pilot trial with D-penicillamine and metacycline in secondary progressive multiple sclerosis.
Topics: Adult; Anti-Bacterial Agents; Antirheumatic Agents; Double-Blind Method; Drug Therapy, Combination; | 1998 |
Penicillamine in multiple sclerosis. Therapeutic trial and design of uncontrolled pilot drug study.
Topics: Adult; Ageusia; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Dyspepsia; Erythema; Fem | 1976 |
5 other studies available for penicillamine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Molecular changes in normal appearing white matter in multiple sclerosis are characteristic of neuroprotective mechanisms against hypoxic insult.
Topics: Aged; Aged, 80 and over; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Aurora Kinases; Bl | 2003 |
Prevention of acute autoimmune encephalomyelitis and abrogation of relapses in murine models of multiple sclerosis by the protease inhibitor D-penicillamine.
Topics: Acute Disease; Animals; Blotting, Northern; Chronic Disease; Collagenases; Encephalomyelitis, Autoim | 1995 |
[D-Penacillamine. From constituent of penicillins to significant drug].
Topics: Arthritis, Rheumatoid; Cystinuria; Hepatitis; Hepatolenticular Degeneration; Humans; Multiple Sclero | 1979 |
Pilot study of d-penicillamine, vitamins and minerals in multiple sclerosis.
Topics: Adult; Autoimmune Diseases; Brain; Dose-Response Relationship, Drug; Female; Humans; Magnesium; Male | 1978 |
Lead and multiple sclerosis.
Topics: Female; Humans; Lead; Lead Poisoning; Male; Multiple Sclerosis; Penicillamine | 1976 |