penicillamine has been researched along with Lung Neoplasms in 8 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In in vitro models of lung and oral cancers, we found D-penicillamine (PenA) to be a most potent protector against CS, both in the absence and presence of saliva (a highly pro-oxidative condition)." | 1.36 | Penicillamine as a potent protector against injurious effects of cigarette smoke in aerodigestive tract cancer. ( Cohen, S; Gavish, M; Leschiner, S; Nagler, R; Otradnov, I; Savulescu, D, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sciegienka, SJ | 1 |
| Solst, SR | 1 |
| Falls, KC | 1 |
| Schoenfeld, JD | 1 |
| Klinger, AR | 1 |
| Ross, NL | 1 |
| Rodman, SN | 1 |
| Spitz, DR | 1 |
| Fath, MA | 1 |
| Nagler, R | 1 |
| Cohen, S | 1 |
| Savulescu, D | 1 |
| Leschiner, S | 1 |
| Otradnov, I | 1 |
| Gavish, M | 1 |
| Chao, JI | 1 |
| Kuo, PC | 1 |
| Hsu, TS | 1 |
| Heagerty, PJ | 1 |
| Zheng, Y | 1 |
| Takenaga, M | 1 |
| Igarashi, R | 1 |
| Ochiai, A | 1 |
| Mizushima, Y | 1 |
| Wurm, K | 1 |
| Brem, SS | 1 |
| Zagzag, D | 1 |
| Tsanaclis, AM | 1 |
| Gately, S | 1 |
| Elkouby, MP | 1 |
| Brien, SE | 1 |
| Levine, GB | 1 |
| Mills, PE | 1 |
| Epstein, WV | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Adaptive, Randomized Phase II Trial to Determine Pathologic Complete Response With the Addition of Carboplatin With and Without Veliparib to Standard Chemotherapy in the Neoadjuvant Treatment of Triple-Negative Breast Cancer[NCT01818063] | Phase 2 | 9 participants (Actual) | Interventional | 2013-04-25 | Completed | ||
| Ependymomics: Multiomic Approach to Radioresistance of Ependymomas in Children and Adolescents[NCT05151718] | 370 participants (Anticipated) | Observational | 2021-09-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
PCR is defined as the absence of any residual invasive cancer on hematoxylin and eosin (H&E) evaluation of the resected breast specimen and all sampled ipsilateral lymph nodes. (NCT01818063)
Timeframe: 36 months following surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Arm 1 (Paclitaxel, Carboplatin) | 3 |
| Arm 2 (Veliparib, Paclitaxel, Carboplatin) | 3 |
1 review available for penicillamine and Lung Neoplasms
| Article | Year |
|---|---|
[Sarcoidosis therapy and its problems today].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Anti-Inflammatory Agents; Antineoplasti | 1978 |
7 other studies available for penicillamine and Lung Neoplasms
| Article | Year |
|---|---|
D-penicillamine combined with inhibitors of hydroperoxide metabolism enhances lung and breast cancer cell responses to radiation and carboplatin via H
Topics: Antineoplastic Combined Chemotherapy Protocols; Auranofin; Breast Neoplasms; Buthionine Sulfoximine; | 2017 |
Penicillamine as a potent protector against injurious effects of cigarette smoke in aerodigestive tract cancer.
Topics: Anticarcinogenic Agents; Cell Line, Tumor; Cell Survival; Humans; Lung Neoplasms; Mouth Neoplasms; P | 2010 |
Down-regulation of survivin in nitric oxide-induced cell growth inhibition and apoptosis of the human lung carcinoma cells.
Topics: Antineoplastic Agents; Apoptosis; Arsenites; Benzazepines; Blotting, Western; Carcinoma; CDC2 Protei | 2004 |
Survival model predictive accuracy and ROC curves.
Topics: Biometry; Humans; Liver Cirrhosis, Biliary; Lung Neoplasms; Models, Statistical; Penicillamine; Pred | 2005 |
Survival model predictive accuracy and ROC curves.
Topics: Biometry; Humans; Liver Cirrhosis, Biliary; Lung Neoplasms; Models, Statistical; Penicillamine; Pred | 2005 |
Survival model predictive accuracy and ROC curves.
Topics: Biometry; Humans; Liver Cirrhosis, Biliary; Lung Neoplasms; Models, Statistical; Penicillamine; Pred | 2005 |
Survival model predictive accuracy and ROC curves.
Topics: Biometry; Humans; Liver Cirrhosis, Biliary; Lung Neoplasms; Models, Statistical; Penicillamine; Pred | 2005 |
Effect of lecithinized superoxide dismutase (PC-SOD) on experimental pulmonary metastasis in mice.
Topics: Animals; Drug Synergism; Female; Free Radicals; Lung; Lung Neoplasms; Mice; Mice, Inbred BALB C; Nit | 1999 |
Inhibition of angiogenesis and tumor growth in the brain. Suppression of endothelial cell turnover by penicillamine and the depletion of copper, an angiogenic cofactor.
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Capillary Permeability; Cell Division; Copper; Diet; Fi | 1990 |
Circulating LgG globulin anti-LgG globulin complex in a patient with carcinoma of the lung and severe neuromyopathy.
Topics: Aged; Arteritis; Autoantibodies; Blood Proteins; Carcinoma, Squamous Cell; Chromatography, Gel; gamm | 1967 |