penicillamine has been researched along with Liver Failure in 6 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Liver Failure: Severe inability of the LIVER to perform its normal metabolic functions, as evidenced by severe JAUNDICE and abnormal serum levels of AMMONIA; BILIRUBIN; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; LACTATE DEHYDROGENASES; and albumin/globulin ratio. (Blakiston's Gould Medical Dictionary, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Bilirubin levels and hepatic encephalopathy improved under MARS therapy." | 3.72 | Liver support--a task for nephrologists? Extracorporeal treatment of a patient with fulminant Wilson crisis. ( Bisse, E; Grotz, W; Manz, T; Ochs, A; Strey, C, 2003) |
| "Hereditary hemochromatosis and Wilson disease are autosomal recessive storage disorders of iron and copper overload, respectively." | 2.50 | Metal storage disorders: Wilson disease and hemochromatosis. ( Kanwar, P; Kowdley, KV, 2014) |
| "Severe hemolytic anemia is an unusual complication of Wilson's disease." | 1.35 | [Acute recurrent hemolytic anemia as the first manifestation of Wilson's disease: Report of a case]. ( Amézyane, T; Badaoui, M; El Khattabi, A; Fatihi, J; Mahassine, F; Ohayon, V; Salaheddine, H; Seddik, H, 2009) |
| "Evaluation of minimal hepatic encephalopathy (MHE) in cirrhotic patients would have prognostic value." | 1.34 | Activation of soluble guanylate cyclase by nitric oxide in lymphocytes correlates with minimal hepatic encephalopathy in cirrhotic patients. ( del Olmo, JA; Felipo, V; Ferrandez, A; Montoliu, C; Piedrafita, B; Rodrigo, JM; Serra, MA, 2007) |
| "She was diagnosed as having fulminant Wilson's disease (FWD)." | 1.32 | Bridging use of plasma exchange and continuous hemodiafiltration before living donor liver transplantation in fulminant Wilson's disease. ( Eto, T; Hamakawa, T; Hasuike, S; Hayashi, K; Ido, A; Nagata, Y; Tanaka, K; Tsubouchi, H; Uto, H, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kanwar, P | 1 |
| Kowdley, KV | 1 |
| El Khattabi, A | 1 |
| Seddik, H | 1 |
| Fatihi, J | 1 |
| Salaheddine, H | 1 |
| Badaoui, M | 1 |
| Amézyane, T | 1 |
| Mahassine, F | 1 |
| Ohayon, V | 1 |
| Manz, T | 1 |
| Ochs, A | 1 |
| Bisse, E | 1 |
| Strey, C | 1 |
| Grotz, W | 1 |
| Nagata, Y | 1 |
| Uto, H | 1 |
| Hasuike, S | 1 |
| Ido, A | 1 |
| Hayashi, K | 1 |
| Eto, T | 1 |
| Hamakawa, T | 1 |
| Tanaka, K | 1 |
| Tsubouchi, H | 1 |
| Sakaida, I | 1 |
| Kawaguchi, K | 1 |
| Kimura, T | 1 |
| Tamura, F | 1 |
| Okita, K | 1 |
| Montoliu, C | 1 |
| Piedrafita, B | 1 |
| Serra, MA | 1 |
| del Olmo, JA | 1 |
| Ferrandez, A | 1 |
| Rodrigo, JM | 1 |
| Felipo, V | 1 |
1 review available for penicillamine and Liver Failure
| Article | Year |
|---|---|
Metal storage disorders: Wilson disease and hemochromatosis.
Topics: Biopsy; Chelating Agents; Disease Progression; Genetic Predisposition to Disease; Genetic Testing; H | 2014 |
5 other studies available for penicillamine and Liver Failure
| Article | Year |
|---|---|
[Acute recurrent hemolytic anemia as the first manifestation of Wilson's disease: Report of a case].
Topics: Acute Disease; Anemia, Hemolytic; Arrhythmias, Cardiac; Chelating Agents; Chelation Therapy; Child; | 2009 |
Liver support--a task for nephrologists? Extracorporeal treatment of a patient with fulminant Wilson crisis.
Topics: Adolescent; Bilirubin; Copper; Female; Hepatic Encephalopathy; Hepatolenticular Degeneration; Humans | 2003 |
Bridging use of plasma exchange and continuous hemodiafiltration before living donor liver transplantation in fulminant Wilson's disease.
Topics: Adolescent; Chelating Agents; Female; Hemodiafiltration; Hepatolenticular Degeneration; Humans; Live | 2003 |
D-Penicillamine improved laparoscopic and histological findings of the liver in a patient with Wilson's disease: 3-year follow-up after diagnosis of Coombs-negative hemolytic anemia of Wilson's disease.
Topics: Adolescent; Anemia, Hemolytic; Antidotes; Biopsy; Coombs Test; Copper; Female; Follow-Up Studies; He | 2005 |
Activation of soluble guanylate cyclase by nitric oxide in lymphocytes correlates with minimal hepatic encephalopathy in cirrhotic patients.
Topics: Adult; Aged; Case-Control Studies; Cyclic GMP; Enzyme Activation; Female; Guanylate Cyclase; Hepatic | 2007 |