Page last updated: 2024-11-07

penicillamine and Liver Cirrhosis

penicillamine has been researched along with Liver Cirrhosis in 114 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
"Serial liver biopsy changes have been reviewed in 30 patients with Indian childhood cirrhosis (ICC) who were randomly allocated to receive treatment with penicillamine in a dose of 20 mg/kg/day, 10 of whom also received prednisolone, and five receiving placebo."9.08Reversal of Indian childhood cirrhosis by D-penicillamine therapy. ( Bavdekar, AR; Bhave, SA; Joshi, VV; Pandit, AN; Pradhan, AM; Tanner, MS, 1995)
"To report a case of early-decompensated liver cirrhosis secondary to discontinuation of penicillamine therapy in a patient with Wilson's disease."7.74Discontinuation of penicillamine in the absence of alternative orphan drugs (trientine-zinc): a case of decompensated liver cirrhosis in Wilson's disease. ( Awaisu, A; Aziz, NA; Ghazali, R; Hassan, Y; Ping, CC, 2007)
"Ursodeoxycholic acid (UDCA) is a beneficial medical therapy for patients with PBC."6.69Long-term ursodeoxycholic acid delays histological progression in primary biliary cirrhosis. ( Angulo, P; Batts, KP; Dickson, ER; Jorgensen, RA; Lindor, KD; Therneau, TM, 1999)
"According to our examinations in case of liver fibrosis cirrhosis induced by CCL4-PB treatment in rats the Pe treatment proved to be unsuccessful."6.38[The effect of D-penicillamine on experimental liver cirrhosis induced by CCl4]. ( Divald, A; Gergely, P; Gonzales Cabello, R; Jeney, A; Lapis, K; Major, J; Schaff, Z; Simon, K; Szende, B; Timár, F, 1990)
"The effect of D-penicillamine (Pe) on liver fibrosis-cirrhosis induced by chronic CCl4 and phenobarbital (Pb) administration in Fischer 344 male rats was studied."5.28The effect of D-penicillamine on CCl4-induced experimental liver cirrhosis. ( Divald, A; Gergely, P; Jeney, A; Lapis, K; Major, J; Schaff, Z; Simon, K; Szende, B; Timár, F, 1991)
"Serial liver biopsy changes have been reviewed in 30 patients with Indian childhood cirrhosis (ICC) who were randomly allocated to receive treatment with penicillamine in a dose of 20 mg/kg/day, 10 of whom also received prednisolone, and five receiving placebo."5.08Reversal of Indian childhood cirrhosis by D-penicillamine therapy. ( Bavdekar, AR; Bhave, SA; Joshi, VV; Pandit, AN; Pradhan, AM; Tanner, MS, 1995)
"Controlled trial of D-penicillamine was carried out with low dosis in 10 patients with chronic persistent hepatitis, 11 patients with chronic aggressive hepatitis and 7 patients with liver cirrhosis."5.05Controlled trial of D-penicillamine with low dosis in the treatment of chronic liver diseases. ( Imura, H; Ito, K; Miyamura, M; Nakano, H; Ohnishi, S; Sugiyama, T; Yamamoto, Y, 1980)
"To report a case of early-decompensated liver cirrhosis secondary to discontinuation of penicillamine therapy in a patient with Wilson's disease."3.74Discontinuation of penicillamine in the absence of alternative orphan drugs (trientine-zinc): a case of decompensated liver cirrhosis in Wilson's disease. ( Awaisu, A; Aziz, NA; Ghazali, R; Hassan, Y; Ping, CC, 2007)
"Cyclic GMP (cGMP) concentration is increased in plasma of patients with liver cirrhosis."3.73Correlation of nitric oxide and atrial natriuretic peptide changes with altered cGMP homeostasis in liver cirrhosis. ( Del Olmo, JA; Felipo, V; Kosenko, E; Montoliu, C; Rodrigo, JM; Serra, MA, 2005)
"Ursodeoxycholic acid (UDCA) is a beneficial medical therapy for patients with PBC."2.69Long-term ursodeoxycholic acid delays histological progression in primary biliary cirrhosis. ( Angulo, P; Batts, KP; Dickson, ER; Jorgensen, RA; Lindor, KD; Therneau, TM, 1999)
"Most patients with Wilson disease become symptomatic between the ages of 6 and 15."2.41[Rare, but important chronic liver diseases]. ( Maier, KP, 2002)
"According to our examinations in case of liver fibrosis cirrhosis induced by CCL4-PB treatment in rats the Pe treatment proved to be unsuccessful."2.38[The effect of D-penicillamine on experimental liver cirrhosis induced by CCl4]. ( Divald, A; Gergely, P; Gonzales Cabello, R; Jeney, A; Lapis, K; Major, J; Schaff, Z; Simon, K; Szende, B; Timár, F, 1990)
"The mortality of liver cirrhosis has doubled during the past two decades and is still increasing in most of the European countries."2.36[Liver fibrosis. 2]. ( Hahn, EG; Martini, GA; Ott, U, 1980)
"The patient was diagnosed with liver cirrhosis 6 years prior based on outside hospital ultrasound and liver biopsy."1.72Wilson's disease: neuropsychiatric presentation and delayed diagnosis. ( Alick-Lindstrom, S; Deme, P; Sheffield, A, 2022)
"Four patients presented with acute liver failure, four with persistently elevated liver function tests, and two with decompensated cirrhosis; none had neurological manifestations."1.48Hepatic manifestations of Wilson's disease: 12-year experience in a Swiss tertiary referral centre. ( Ferenci, P; Fraga, M; Giostra, E; Hiroz, P; Moradpour, D; Saldarriaga, J; Sempoux, C; Vieira Barbosa, J, 2018)
"Sixty patients with liver fibrosis induced by hepatolenticular degeneration were randomly divided into two groups, a penicillamine group and a BMSCs plus penicillamine group, with 30 patients in each."1.46A clinical study of bone mesenchymal stem cells for the treatment of hepatic fibrosis induced by hepatolenticular degeneration. ( Zhang, D, 2017)
"Wilson disease is a disorder of copper metabolism characterized by copper overload."1.35Effect of D-penicillamine on liver fibrosis and inflammation in Wilson disease. ( Bahador, A; Dehghani, M; Dehghani, SM; Geramizadeh, B; Kakaei, F; Kazemi, K; Malek-Hosseini, SA; Nikeghbalian, S; Reza Nejatollahi, SM; Salahi, H, 2008)
"Evaluation of minimal hepatic encephalopathy (MHE) in cirrhotic patients would have prognostic value."1.34Activation of soluble guanylate cyclase by nitric oxide in lymphocytes correlates with minimal hepatic encephalopathy in cirrhotic patients. ( del Olmo, JA; Felipo, V; Ferrandez, A; Montoliu, C; Piedrafita, B; Rodrigo, JM; Serra, MA, 2007)
"A case of a patient is reported in whom Wilson's disease presented in debut with a picture of decompensated liver cirrhosis and immune thrombocytopania complicated by recurrent hemorrhagic syndrome."1.32[Wilson's disease and secondary copper hemochromatoses in hematological practice]. ( Levina, AA; Lukina, EA; Solov'eva, TI; Sysoeva, EP; Vorob'ev, AI, 2004)
"We conclude that Wilson's disease may be a good indication for LTX for both neurological manifestation with stable liver function and hepatic manifestation with cirrhosis or acute liver failure."1.30Liver transplantation: treatment of choice for hepatic and neurological manifestation of Wilson's disease. ( Bechstein, WO; Becker, M; Luck, W; Mueller, AR; Neuhaus, P; Neuhaus, R; Platz, KP; Schuelke, M; Schumacher, G; Steinmüller, T, 1997)
"Major depressive disorder was the first clinical manifestation at the age of 38 years."1.30Psychiatric symptoms as late onset of Wilson's disease: neuroradiological findings, clinical features and treatment. ( Bergamasco, B; Crasto, S; Keller, R; Lagget, M; Torta, R, 1999)
"A patient with untreated Wilson's disease showed the possibility of fetal liver damage and copper accumulation in the placenta by this disease."1.29Copper disposition of the fetus and placenta in a patient with untreated Wilson's disease. ( Anai, T; Inoue, I; Matsui, N; Miyakawa, I; Oga, M; Yoshimatsu, J, 1993)
"The effect of D-penicillamine (Pe) on liver fibrosis-cirrhosis induced by chronic CCl4 and phenobarbital (Pb) administration in Fischer 344 male rats was studied."1.28The effect of D-penicillamine on CCl4-induced experimental liver cirrhosis. ( Divald, A; Gergely, P; Jeney, A; Lapis, K; Major, J; Schaff, Z; Simon, K; Szende, B; Timár, F, 1991)
"Twenty of 320 patients with Wilson's disease initially presented with chemical and laboratory features of chronic active hepatitis, confirmed histologically in 17."1.28Prognosis of Wilsonian chronic active hepatitis. ( Scheinberg, IH; Schilsky, ML; Sternlieb, I, 1991)
"Oral zinc therapy in Wilson's Disease may be regarded as an alternative to D-Penicillamine treatment when this drug has to be discontinued because of side effects."1.27[Oral zinc in Wilson disease--an alternative to D-penicillamine]. ( Dormeyer, HH; Hütteroth, T; Keidl, E; Manns, M; Meyer zum Büschenfelde, KH; Ramadori, G, 1985)
"During childhood, Wilson's disease becomes manifest mostly in the hepatic form."1.26[Morbus Wilson--pathogenesis, diagnosis, therapy, and course (author's transl)]. ( Helwig, H; Werner, JP, 1977)
"Thus, since Wilson's disease may present with chronic active hepatitis or cirrhosis with a normal ESR and without ocular or neurologic signs, it may be a more common cause of liver disease in young people than has been appreciated."1.26Wilson's disease: a common liver disorder? ( Barr, R; Hyslop, PS; Sass-Kortsak, A; Thompson, WG, 1977)

Research

Studies (114)

TimeframeStudies, this research(%)All Research%
pre-199073 (64.04)18.7374
1990's17 (14.91)18.2507
2000's11 (9.65)29.6817
2010's12 (10.53)24.3611
2020's1 (0.88)2.80

Authors

AuthorsStudies
Deme, P1
Sheffield, A1
Alick-Lindstrom, S1
Vieira Barbosa, J1
Fraga, M1
Saldarriaga, J1
Hiroz, P1
Giostra, E1
Sempoux, C1
Ferenci, P1
Moradpour, D1
Gerosa, C1
Fanni, D2
Congiu, T1
Piras, M1
Cau, F1
Moi, M1
Faa, G2
Idrissi, ML1
Babakhoya, A1
Khabbache, K1
Souilmi, F1
Benmiloud, S1
Abourrazak, S1
Chaouki, S1
Atmani, S1
Bouharrou, A1
Hida, M1
Mareček, Z1
Brůha, R1
Fieten, H2
Penning, LC1
Leegwater, PA2
Rothuizen, J2
Zhang, D1
Kazemi, K1
Geramizadeh, B1
Nikeghbalian, S1
Salahi, H1
Bahador, A1
Reza Nejatollahi, SM1
Dehghani, SM1
Dehghani, M1
Kakaei, F1
Malek-Hosseini, SA1
Seo, JY1
Kim, SY1
Choi, WC1
Cocco, GA1
Loudianos, G2
Pes, GM1
Tolu, F1
Lepori, MB2
Barrocu, M1
Sechi, GP1
Cope-Yokoyama, S1
Finegold, MJ2
Sturniolo, GC1
Kim, K1
Mescoli, C1
Rugge, M1
Medici, V1
Roy, DN1
Sen, G1
Chowdhury, KD1
Biswas, T1
Gucev, ZS1
Pop-Jordanova, N1
Calovska, V1
Tasic, V1
Slavevska, N1
Laban, N1
Noli, MC1
Moores, A1
Fox, S1
Lang, A1
Hirschfield, GM1
Sini, M1
Sorbello, O1
Sanna, F1
Battolu, F1
Civolani, A1
Demelia, L1
Dirksen, K1
van den Ingh, TS1
Winter, EA1
Watson, AL1
Maier, KP1
Rakhimova, OIu1
Rozina, TP1
Ignatova, TM1
STERNLIEB, I3
Mandrekar, SJ1
Mandrekar, JN1
Vorob'ev, AI1
Lukina, EA1
Sysoeva, EP1
Levina, AA1
Solov'eva, TI1
Montoliu, C2
Kosenko, E1
Del Olmo, JA2
Serra, MA2
Rodrigo, JM2
Felipo, V2
Piedrafita, B1
Ferrandez, A1
Ping, CC1
Hassan, Y1
Aziz, NA1
Ghazali, R1
Awaisu, A1
Hauftová, D1
Hartl, J1
Slavícek, J1
Valach, V1
Fialová, J1
Pojerová, M1
Hahn, EG1
Ott, U1
Martini, GA1
Paumgartner, G1
Ferraccioli, GF1
Baldini, A1
Ambanelli, U1
Berg, PA1
Marcus, SN1
Chadwick, D1
Walker, RJ1
Nakano, H1
Ohnishi, S1
Sugiyama, T1
Miyamura, M1
Imura, H1
Yamamoto, Y1
Ito, K1
Weinzierl, M1
Kruis, W1
Eisenburg, J2
Mörl, M3
Thierman-Duffaud, D1
Lévy, VG1
Pigrau Serrallach, C1
Pahissa Berga, A1
Clotet Sala, B1
Guardia Massó, J1
Gichev, IuP1
Bakulina, LF1
Pradhan, AM3
Bhave, SA3
Joshi, VV1
Bavdekar, AR2
Pandit, AN3
Tanner, MS6
Horslen, SP1
Lyon, TD1
Fell, GS1
Lowry, MF1
Oga, M1
Matsui, N1
Anai, T1
Yoshimatsu, J1
Inoue, I1
Miyakawa, I1
Schumacher, G1
Platz, KP1
Mueller, AR1
Neuhaus, R1
Steinmüller, T1
Bechstein, WO1
Becker, M1
Luck, W1
Schuelke, M1
Neuhaus, P1
Angulo, P2
Batts, KP2
Therneau, TM2
Jorgensen, RA1
Dickson, ER1
Lindor, KD2
Larson, DR1
LaRusso, NF1
Keller, R1
Torta, R1
Lagget, M1
Crasto, S1
Bergamasco, B1
Svegliati-Baroni, G1
Saccomanno, S1
van Goor, H1
Jansen, P1
Benedetti, A1
Moshage, H1
Kuntz, HD1
May, B1
Ulmer, WT1
Mezey, E1
Potter, JJ1
Iber, FL2
Maddrey, WC1
Wallnöfer, H1
Jackson, DS1
Friedrich, K1
Henning, H1
Nisman, RM1
Ganderson, AP1
Vlahcevic, ZR1
Gregory, DH1
Talke, H1
Werner, JP1
Helwig, H1
Thaler, H1
Szepesi, T1
Szepesi, G1
Pusch, JH1
Ullmann, W1
Gabriel, L1
Thompson, WG1
Hyslop, PS1
Barr, R1
Sass-Kortsak, A1
Davcev, P1
Vanovski, B1
Bidikov, V1
Moritz, AJ1
Bielawski, W1
Kaszewska-Jablońska, I1
Górski, M1
Adamson, M1
Reiner, B1
Olson, JL1
Goodman, Z1
Plotnick, L1
Bernardini, I1
Gahl, WA1
Schaff, Z2
Lapis, K2
Szende, B2
Jeney, A2
Gergely, P2
Simon, K2
Divald, A2
Timár, F2
Major, J2
Singh, S2
Kohli, V1
Johnson, PJ1
Williams, R1
Schilsky, ML1
Scheinberg, IH1
Bhusnurmath, SR1
Walia, BN1
Parkash, D1
Radotra, BD1
Nath, R1
Gonzales Cabello, R1
Walshe, JM1
Dixon, AK1
Barrow, L1
Tarantino, G1
Guardascione, AM1
Rossi, A1
Carandente, B1
Ciccarelli, AF1
De Michele, NG1
De Rosa, G1
Pannain, M1
Camus, JP1
Koeger, AC1
Last, JA1
Manghani, DK1
Dastur, DK1
Ramadori, G1
Keidl, E1
Hütteroth, T1
Dormeyer, HH1
Manns, M1
Meyer zum Büschenfelde, KH1
Elmes, ME1
Levi, AJ1
Sherlock, S2
Scheuer, PJ1
Cumings, JN1
Smallwood, RA1
Williams, HA1
Rosenoer, VM1
Danks, DM1
Stevens, BJ1
Alexander, M2
Wille, G1
Wildhirt, E1
Henrich, M1
Bannaski, H1
Furrer, HU1
Tönz, O1
Scheiffarth, F1
Lössner, J1
Eichner, B1
Bachmann, H1
Biesold, D1
Günther, K1
Thomas, M1
Schnack, H2
Resnick, RH1
Boitnott, J1
Makopour, H1
Cerda, JJ1
Markoff, N1
Gros, H1
Zwirner, K1
Herzog, W1
Lynch, RE1
Lee, GR1
Cartwright, GE1
Albukerk, JN1
Grasedyck, K1
Jarstorff, G1
Trux, F1
Hansen, HJ1
Andersen, OS2
Blattner, RJ1
Bickel, H1
Becker, K1
Falkmer, S1
Samuelson, G1
Sjölin, S1
Brailski, C1
Kolarski, V1
Krastev, I1
Leu, ML1
Strickland, GT2
Gutman, RA1
Lange, J1
Schumacher, K1
Witscher, HP1
Slovis, TL1
Dubois, RS1
Rodgerson, DO1
Silverman, A1
O'Reilly, S1
Weber, PM1
Beckner, WM1
Shipley, L1
Boudin, G1
Pépin, B1
Milhaud, M1
Jérome, H1
Pacilly, A1
Hansen, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy and Security of Bezafibrate in Patients With Primary Biliary Cirrhosis Without Biochemical Response to Ursodeoxycholic Acid: A Randomized, Double-blind, Placebo-controlled Trial[NCT02937012]Phase 334 participants (Anticipated)Interventional2016-10-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

20 reviews available for penicillamine and Liver Cirrhosis

ArticleYear
Liver pathology in Wilson's disease: From copper overload to cirrhosis.
    Journal of inorganic biochemistry, 2019, Volume: 193

    Topics: Copper; Copper-Transporting ATPases; Epigenesis, Genetic; Hepatolenticular Degeneration; Humans; Liv

2019
[Wilson's disease in the child: apropos of 20 cases].
    The Pan African medical journal, 2013, Volume: 14

    Topics: Adolescent; Anemia, Hemolytic; Ceruloplasmin; Chelation Therapy; Child; Child, Preschool; Consanguin

2013
[Wilsons disease].
    Vnitrni lekarstvi, 2013, Volume: 59, Issue:7

    Topics: Adenosine Triphosphatases; Adult; Cation Transport Proteins; Chelating Agents; Copper; Copper-Transp

2013
[Rare, but important chronic liver diseases].
    Praxis, 2002, Nov-27, Volume: 91, Issue:48

    Topics: Adolescent; Adult; Biopsy; Ceruloplasmin; Chelating Agents; Child; Chronic Disease; Copper; Diabetes

2002
[Liver fibrosis. 2].
    Zeitschrift fur Gastroenterologie, 1980, Volume: 18, Issue:10

    Topics: Acetylglucosaminidase; Aminopropionitrile; Animals; Collagen; Connective Tissue; Female; Fibroblasts

1980
[Therapy of liver cirrhosis].
    Zeitschrift fur Gastroenterologie. Verhandlungsband, 1983, Volume: 18

    Topics: Adrenal Cortex Hormones; Azathioprine; Chronic Disease; Colchicine; Hepatitis; Humans; Liver Cirrhos

1983
[Clinical aspects and immunology of chronic active autoimmune hepatitis and primary biliary cirrhosis].
    Immunitat und Infektion, 1982, Volume: 10, Issue:1

    Topics: Adrenal Cortex Hormones; Autoantibodies; Azathioprine; Chronic Disease; Hepatitis; Humans; Liver Cir

1982
[Typical risks in the treatment of acute and chronic liver diseases].
    Der Internist, 1982, Volume: 23, Issue:3

    Topics: Androgens; Ascites; Cholestyramine Resin; Cimetidine; Disseminated Intravascular Coagulation; Diuret

1982
Role of copper in Indian childhood cirrhosis.
    The American journal of clinical nutrition, 1998, Volume: 67, Issue:5 Suppl

    Topics: Chelating Agents; Child, Preschool; Copper; Diet; Humans; India; Infant; Liver Cirrhosis; Penicillam

1998
Possible modification of scar tissue by biochemical methods.
    Equine veterinary journal, 1979, Volume: 11, Issue:2

    Topics: Aminopropionitrile; Animals; Cicatrix; Collagen; Cortisone; Humans; Hydroxylysine; Hydroxyproline; L

1979
[Long-term treatment of chronic hepatitis and liver cirrhosis].
    Medizinische Klinik, 1975, Apr-11, Volume: 70, Issue:15

    Topics: Adrenal Cortex Hormones; Anabolic Agents; Chronic Disease; Diagnosis, Differential; Diet Therapy; Di

1975
The development of cirrhosis in Wilson's disease.
    Clinics in gastroenterology, 1975, Volume: 4, Issue:2

    Topics: Ceruloplasmin; Copper; Cornea; Cytosol; Hepatolenticular Degeneration; Humans; Liver; Liver Cirrhosi

1975
D-penicillamine.
    Indian pediatrics, 1991, Volume: 28, Issue:7

    Topics: Child; Hepatolenticular Degeneration; Humans; India; Liver Cirrhosis; Penicillamine

1991
[The effect of D-penicillamine on experimental liver cirrhosis induced by CCl4].
    Morphologiai es igazsagugyi orvosi szemle, 1990, Volume: 30, Issue:3

    Topics: Animals; Carbon Tetrachloride; Humans; Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Penici

1990
[D-penicillamine and collagen].
    Annales de biologie clinique, 1986, Volume: 44, Issue:3

    Topics: Aminopropionitrile; Arthritis, Rheumatoid; Autoantibodies; Bronchi; Cicatrix; Collagen; Collagen Dis

1986
Changes in the collagen pathway in fibrosis.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Colchicine; Collagen; Connective Tissue Diseases; Cross-Linking R

1985
Wilson's disease and copper metabolism--a review.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 1985, Volume: 4, Issue:2

    Topics: Brain; Ceruloplasmin; Child; Copper; Cornea; Hepatolenticular Degeneration; Humans; India; Kidney; L

1985
[Long-term therapy of liver diseases].
    Wiener medizinische Wochenschrift (1946), 1972, Feb-12, Volume: 122, Issue:7

    Topics: Aged; Anabolic Agents; Chronic Disease; Cortisone; Diet Therapy; Fatty Liver; Female; Fluorouracil;

1972
[Hepatolenticular degeneration. Wilson's disease].
    Ugeskrift for laeger, 1969, Jul-31, Volume: 131, Issue:31

    Topics: Age Factors; Ceruloplasmin; Copper; Hepatolenticular Degeneration; Humans; Liver Cirrhosis; Penicill

1969
[Wilson's disease (hepatolenticular degeneration)].
    Der Internist, 1966, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Biopsy; Brain; Ceruloplasmin; Child; Copper; Dimercaprol; Edetic Acid; Hepatolent

1966

Trials

6 trials available for penicillamine and Liver Cirrhosis

ArticleYear
Controlled trial of D-penicillamine with low dosis in the treatment of chronic liver diseases.
    Gastroenterologia Japonica, 1980, Volume: 15, Issue:4

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Chronic Disease; Clinical Trials as To

1980
Reversal of Indian childhood cirrhosis by D-penicillamine therapy.
    Journal of pediatric gastroenterology and nutrition, 1995, Volume: 20, Issue:1

    Topics: Biopsy; Copper; Female; Fibrosis; Humans; India; Infant; Inflammation; Liver; Liver Cirrhosis; Male;

1995
Long term survival in Indian childhood cirrhosis treated with D-penicillamine.
    Archives of disease in childhood, 1996, Volume: 74, Issue:1

    Topics: Chelating Agents; Child, Preschool; Chronic Disease; Female; Follow-Up Studies; Humans; India; Infan

1996
Long-term ursodeoxycholic acid delays histological progression in primary biliary cirrhosis.
    Hepatology (Baltimore, Md.), 1999, Volume: 29, Issue:3

    Topics: Adult; Aged; Cholagogues and Choleretics; Disease Progression; Female; Humans; Liver Cirrhosis; Live

1999
Clinical trials of penicillamine in Indian childhood cirrhosis.
    Archives of disease in childhood, 1987, Volume: 62, Issue:11

    Topics: Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; India; Inf

1987
Preliminary observations of d-penicillamine therapy in acute alcoholic liver disease.
    Digestion, 1974, Volume: 11, Issue:3-4

    Topics: Acute Disease; Adult; Albumins; Alcoholism; Biopsy; Clinical Trials as Topic; Female; Globulins; Hep

1974

Other Studies

88 other studies available for penicillamine and Liver Cirrhosis

ArticleYear
Wilson's disease: neuropsychiatric presentation and delayed diagnosis.
    BMJ case reports, 2022, Jul-04, Volume: 15, Issue:7

    Topics: Ataxia; Delayed Diagnosis; Female; Hepatolenticular Degeneration; Humans; Liver Cirrhosis; Penicilla

2022
Hepatic manifestations of Wilson's disease: 12-year experience in a Swiss tertiary referral centre.
    Swiss medical weekly, 2018, 12-17, Volume: 148

    Topics: Adult; Chelating Agents; Copper; Copper-Transporting ATPases; Female; Hepatolenticular Degeneration;

2018
New canine models of copper toxicosis: diagnosis, treatment, and genetics.
    Annals of the New York Academy of Sciences, 2014, Volume: 1314

    Topics: Adaptor Proteins, Signal Transducing; Animals; Chromosome Deletion; Copper; Disease Models, Animal;

2014
A clinical study of bone mesenchymal stem cells for the treatment of hepatic fibrosis induced by hepatolenticular degeneration.
    Genetics and molecular research : GMR, 2017, Mar-15, Volume: 16, Issue:1

    Topics: Adult; Biomarkers; Case-Control Studies; Cells, Cultured; Chelating Agents; Combined Modality Therap

2017
Effect of D-penicillamine on liver fibrosis and inflammation in Wilson disease.
    Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation, 2008, Volume: 6, Issue:4

    Topics: Adolescent; Adult; Chelating Agents; Child; Child, Preschool; Copper; Disease Progression; Female; H

2008
Education and imaging. Hepatobiliary and pancreatic: hypersensitivity pneumonitis induced by penicillamine.
    Journal of gastroenterology and hepatology, 2009, Volume: 24, Issue:4

    Topics: Alveolitis, Extrinsic Allergic; Chelating Agents; Female; Hepatolenticular Degeneration; Humans; Liv

2009
"Acquired" hepatocerebral degeneration in a patient heterozygote carrier for a novel mutation in ATP7B gene.
    Movement disorders : official journal of the Movement Disorder Society, 2009, Aug-15, Volume: 24, Issue:11

    Topics: Adenosine Triphosphatases; Adult; Amino Acid Substitution; Basal Ganglia; Cation Transport Proteins;

2009
Wilson disease: histopathological correlations with treatment on follow-up liver biopsies.
    World journal of gastroenterology, 2010, Mar-28, Volume: 16, Issue:12

    Topics: Adolescent; Adult; Alanine Transaminase; Aspartate Aminotransferases; Biomarkers; Biopsy; Chelating

2010
Combination therapy with andrographolide and d-penicillamine enhanced therapeutic advantage over monotherapy with d-penicillamine in attenuating fibrogenic response and cell death in the periportal zone of liver in rats during copper toxicosis.
    Toxicology and applied pharmacology, 2011, Jan-01, Volume: 250, Issue:1

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Apoptosis; Biomarkers; Caspases; Copper; Di

2011
Acute Gallbladder Hydrops and Arthritis: unusual initial manifestations of Wilson's Disease (WD): Case Report.
    Prilozi, 2011, Volume: 32, Issue:2

    Topics: Adenosine Triphosphatases; Arthritis; Cation Transport Proteins; Ceruloplasmin; Chelating Agents; Ch

2011
Wilson disease: Canadian perspectives on presentation and outcomes from an adult ambulatory setting.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2012, Volume: 26, Issue:6

    Topics: Adolescent; Adult; Ambulatory Care; Biopsy; Brain Diseases; Canada; Chelating Agents; Child; Female;

2012
Histologic evolution and long-term outcome of Wilson's disease: results of a single-center experience.
    European journal of gastroenterology & hepatology, 2013, Volume: 25, Issue:1

    Topics: Adolescent; Adult; Biopsy; Chelating Agents; Chi-Square Distribution; Child; Child, Preschool; Disea

2013
D-penicillamine treatment of copper-associated hepatitis in Labrador retrievers.
    Veterinary journal (London, England : 1997), 2013, Volume: 196, Issue:3

    Topics: Animals; Copper; Dog Diseases; Dogs; Female; Genetic Predisposition to Disease; Liver Cirrhosis; Mal

2013
[Nephrolithiasis as an initial clinical manifestation of Wilson-Konovalov disease].
    Terapevticheskii arkhiv, 2003, Volume: 75, Issue:6

    Topics: Adolescent; Adult; Chelating Agents; Diagnosis, Differential; Female; Hepatolenticular Degeneration;

2003
WILSON'S DISEASE AS A GASTROENTEROLOGIC PROBLEM.
    The American journal of gastroenterology, 1964, Volume: 42

    Topics: Copper; Diet; Diet Therapy; Dimercaprol; Gastroenterology; Genetics, Medical; Hepatolenticular Degen

1964
Are our data symmetric?
    Statistical methods in medical research, 2003, Volume: 12, Issue:6

    Topics: Biometry; Chelating Agents; Cholesterol; Data Interpretation, Statistical; Humans; Liver Cirrhosis;

2003
[Wilson's disease and secondary copper hemochromatoses in hematological practice].
    Terapevticheskii arkhiv, 2004, Volume: 76, Issue:7

    Topics: Adult; Chelating Agents; Copper; Diagnosis, Differential; Drug Administration Schedule; Hemochromato

2004
Correlation of nitric oxide and atrial natriuretic peptide changes with altered cGMP homeostasis in liver cirrhosis.
    Liver international : official journal of the International Association for the Study of the Liver, 2005, Volume: 25, Issue:4

    Topics: Adult; Aged; Ascites; Atrial Natriuretic Factor; Cells, Cultured; Cyclic GMP; Guanylate Cyclase; Hum

2005
Activation of soluble guanylate cyclase by nitric oxide in lymphocytes correlates with minimal hepatic encephalopathy in cirrhotic patients.
    Journal of molecular medicine (Berlin, Germany), 2007, Volume: 85, Issue:3

    Topics: Adult; Aged; Case-Control Studies; Cyclic GMP; Enzyme Activation; Female; Guanylate Cyclase; Hepatic

2007
Discontinuation of penicillamine in the absence of alternative orphan drugs (trientine-zinc): a case of decompensated liver cirrhosis in Wilson's disease.
    Journal of clinical pharmacy and therapeutics, 2007, Volume: 32, Issue:1

    Topics: Adult; Chelating Agents; Fatal Outcome; Female; Hepatolenticular Degeneration; Humans; Liver Cirrhos

2007
[Hepatic changes in the neurological form of Wilson's disease].
    Vnitrni lekarstvi, 1967, Volume: 13, Issue:11

    Topics: Adolescent; Adult; Female; Hepatolenticular Degeneration; Humans; Liver Cirrhosis; Male; Penicillami

1967
[Reactive SH-groups in clinical practice. Methodological notes].
    Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma, 1981, Volume: 52, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Citrates; Darkness; Diabetes Mellitus;

1981
D-penicillamine-induced myasthenia gravis in primary biliary cirrhosis.
    Gastroenterology, 1984, Volume: 86, Issue:1

    Topics: Autoantibodies; Electromyography; Female; Humans; Liver Cirrhosis; Middle Aged; Myasthenia Gravis; P

1984
[Myasthenia syndrome in D-penicillamine therapy in primary biliary cirrhosis].
    Der Internist, 1981, Volume: 22, Issue:2

    Topics: Adult; Copper; Female; Humans; Liver; Liver Cirrhosis; Myasthenia Gravis; Penicillamine

1981
[Main characteristics of the treatment of liver cirrhosis].
    Therapie der Gegenwart, 1981, Volume: 120, Issue:5

    Topics: Adolescent; Adult; Ascites; Bed Rest; Bloodletting; Child; Child, Preschool; Cholestyramine Resin; D

1981
[Copper metabolism: ultimate therapeutic implications in cholestasis].
    Medecine & chirurgie digestives, 1981, Volume: 10, Issue:4

    Topics: Cholestasis; Copper; Hepatolenticular Degeneration; Humans; Liver; Liver Cirrhosis; Penicillamine

1981
[Wilson's disease: seven cases with hepatic onset (author's transl)].
    Medicina clinica, 1981, Nov-25, Volume: 77, Issue:9

    Topics: Adolescent; Adult; Child; Copper; Female; Hepatitis; Hepatolenticular Degeneration; Humans; Liver; L

1981
[Study of the in vitro effect of hydrocortisone and D-penicillamine on the liver of patients with chronic hepatitis and liver cirrhosis].
    Terapevticheskii arkhiv, 1980, Volume: 52, Issue:7

    Topics: Chronic Disease; Drug Evaluation, Preclinical; Glucocorticoids; Hepatitis; Humans; Hydrocortisone; L

1980
Copper associated childhood cirrhosis.
    Gut, 1994, Volume: 35, Issue:10

    Topics: Bangladesh; Child, Preschool; Copper; Humans; Isotopes; Liver; Liver Cirrhosis; Male; Penicillamine;

1994
Copper disposition of the fetus and placenta in a patient with untreated Wilson's disease.
    American journal of obstetrics and gynecology, 1993, Volume: 169, Issue:1

    Topics: Adult; Ceruloplasmin; Copper; Female; Fetal Diseases; Fetus; Hepatolenticular Degeneration; Humans;

1993
Liver transplantation: treatment of choice for hepatic and neurological manifestation of Wilson's disease.
    Clinical transplantation, 1997, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Anemia, Hemolytic; Ataxia; Chelating Agents; Deglutition Disorders; Dysarthria; D

1997
Time course of histological progression in primary sclerosing cholangitis.
    The American journal of gastroenterology, 1999, Volume: 94, Issue:11

    Topics: Adolescent; Adult; Aged; Biopsy; Cholagogues and Choleretics; Cholangitis, Sclerosing; Disease Progr

1999
Psychiatric symptoms as late onset of Wilson's disease: neuroradiological findings, clinical features and treatment.
    Italian journal of neurological sciences, 1999, Volume: 20, Issue:1

    Topics: Adult; Age of Onset; Antidepressive Agents; Basal Ganglia; Basal Ganglia Diseases; Biopsy; Bipolar D

1999
Involvement of reactive oxygen species and nitric oxide radicals in activation and proliferation of rat hepatic stellate cells.
    Liver, 2001, Volume: 21, Issue:1

    Topics: Animals; Ascorbic Acid; Cell Division; Cells, Cultured; Dimethylnitrosamine; Disease Models, Animal;

2001
[Wilson's disease or liver cirrhosis of a different etiology].
    MMW, Munchener medizinische Wochenschrift, 1979, Nov-16, Volume: 121, Issue:46

    Topics: Adolescent; Ceruloplasmin; Copper; Corneal Diseases; Diagnosis, Differential; Female; Hepatolenticul

1979
Hepatic collagen proline hydroxylase activity in alcoholic hepatitis: effect of d-penicillamine.
    The Journal of laboratory and clinical medicine, 1979, Volume: 93, Issue:1

    Topics: Adult; Aged; Aspartate Aminotransferases; Collagen; Fatty Liver; Female; Glycosaminoglycans; Hepatit

1979
[Fundamental aspects of diagnosis and therapy of chronic hepatitis and cirrhosis].
    Wiener medizinische Wochenschrift. Supplement, 1977, Volume: 44

    Topics: Adult; Antibodies, Antinuclear; Austria; Chemical and Drug Induced Liver Injury; Female; Hepatitis;

1977
[Spontaneous and DL-penicillamine-induced renal copper excretion in liver diseases (author's transl)].
    Zeitschrift fur Gastroenterologie, 1979, Volume: 17, Issue:3

    Topics: Copper; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Penicillamine

1979
Acute viral hepatitis with bridging hepatic necrosis. An overview.
    Archives of internal medicine, 1979, Volume: 139, Issue:11

    Topics: Adrenal Cortex Hormones; Biopsy; Hepatitis, Viral, Human; Humans; Liver; Liver Cirrhosis; Necrosis;

1979
[Treatment of liver cirrhosis and its complications].
    La Clinica terapeutica, 1979, Apr-15, Volume: 89, Issue:1

    Topics: Ascites; Azathioprine; Barbiturates; Hemochromatosis; Hepatic Encephalopathy; Hepatolenticular Degen

1979
[Morbus Wilson--pathogenesis, diagnosis, therapy, and course (author's transl)].
    Monatsschrift fur Kinderheilkunde, 1977, Volume: 125, Issue:12

    Topics: Age Factors; Ceruloplasmin; Child; Copper; Hemolysis; Hepatolenticular Degeneration; Humans; Liver C

1977
[Results of treatment of chronic hepatitis (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1978, Nov-10, Volume: 103, Issue:45

    Topics: Adolescent; Adult; Aged; Aspartate Aminotransferases; Azathioprine; Child; Child, Preschool; Chronic

1978
[Liver cirrhosis caused by genetic defects].
    Medizinische Klinik, 1977, Mar-25, Volume: 72, Issue:12

    Topics: Adult; Bloodletting; Hemochromatosis; Hepatolenticular Degeneration; Humans; Liver Cirrhosis; Male;

1977
[Therapy and prognosis of chronic hepatitis].
    Fortschritte der Medizin, 1977, Mar-17, Volume: 95, Issue:11

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Chronic Disease; Drug Therapy, Combination; Hepatitis,

1977
Wilson's disease: a common liver disorder?
    Canadian Medical Association journal, 1977, Jul-09, Volume: 117, Issue:1

    Topics: Adolescent; Adult; Aspartate Aminotransferases; Blood Sedimentation; Ceruloplasmin; Child; Copper; E

1977
[Therapeutic procedures in chronic hepatitis and liver cirrhosis].
    Godisen zbornik na Medicinskiot fakultet vo Skopje, 1976, Volume: 22

    Topics: Adrenal Cortex Hormones; Chronic Disease; Female; Hepatitis; Humans; Immunosuppressive Agents; Liver

1976
[Biosynthesis of collagen and mode of action of D-penicillamine (author's transl)].
    Wiener klinische Wochenschrift, 1975, Jan-10, Volume: 87, Issue:1

    Topics: Amino Acids; Animals; Aorta; Binding Sites; Cartilage; Collagen; Connective Tissue; Hepatitis; Human

1975
[Results of controlled therapeutic trials of D-penicillamine in chronic hepatitis].
    Polskie Archiwum Medycyny Wewnetrznej, 1976, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Aged; Chronic Disease; Drug Evaluation; Female; Hepatitis; Humans; Liver Cirrhosi

1976
Indian childhood cirrhosis in an American child.
    Gastroenterology, 1992, Volume: 102, Issue:5

    Topics: Copper; Humans; Infant; Liver Cirrhosis; Male; Penicillamine

1992
The effect of D-penicillamine on CCl4-induced experimental liver cirrhosis.
    Experimental pathology, 1991, Volume: 43, Issue:1-2

    Topics: Animals; Carbon Tetrachloride; Collagen; Connective Tissue; Liver; Liver Cirrhosis; Male; Microscopy

1991
Excellent prognosis in Wilsonian chronic active hepatitis: new data or an article of faith?
    Hepatology (Baltimore, Md.), 1991, Volume: 14, Issue:6

    Topics: Hepatitis, Chronic; Hepatolenticular Degeneration; Humans; Liver Cirrhosis; Penicillamine; Prognosis

1991
Prognosis of Wilsonian chronic active hepatitis.
    Gastroenterology, 1991, Volume: 100, Issue:3

    Topics: Adolescent; Adult; Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Child; Copper; Fema

1991
Successful treatment of Indian childhood cirrhosis.
    Human pathology, 1991, Volume: 22, Issue:7

    Topics: Child, Preschool; Copper; Humans; India; Infant; Liver; Liver Cirrhosis; Penicillamine

1991
Sequential histopathologic alterations in Indian childhood cirrhosis treated with d-penicillamine.
    Human pathology, 1991, Volume: 22, Issue:7

    Topics: Copper; Female; Humans; India; Infant; Liver; Liver Cirrhosis; Male; Penicillamine

1991
Dangers of non-compliance in Wilson's disease.
    Lancet (London, England), 1986, Apr-12, Volume: 1, Issue:8485

    Topics: Acute Disease; Adolescent; Ascites; Brain Chemistry; Copper; Female; Follow-Up Studies; Hepatolentic

1986
Penicillamine in Indian childhood cirrhosis.
    Lancet (London, England), 1987, Aug-29, Volume: 2, Issue:8557

    Topics: Child; Copper; Drug Evaluation; Humans; India; Liver Cirrhosis; Penicillamine

1987
D-penicillamine in patients with postnecrotic liver cirrhosis.
    Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques, 1988, Volume: 10, Issue:1

    Topics: Female; Humans; Liver Cirrhosis; Male; Middle Aged; Penicillamine

1988
[Oral zinc in Wilson disease--an alternative to D-penicillamine].
    Zeitschrift fur Gastroenterologie, 1985, Volume: 23, Issue:1

    Topics: Administration, Oral; Adult; Hepatolenticular Degeneration; Humans; Liver Cirrhosis; Liver Function

1985
Letter: Anti-inflammatory drugs and tissue copper.
    Lancet (London, England), 1974, Nov-30, Volume: 2, Issue:7892

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Copper; Humans; Liver Cirrhosis; Penicillamine; Pro

1974
Presymptomatic Wilson's disease.
    Lancet (London, England), 1967, Sep-16, Volume: 2, Issue:7516

    Topics: Adolescent; Adult; Biopsy; Ceruloplasmin; Child; Child, Preschool; Copper; Fatty Liver; Hepatolentic

1967
Liver-copper levels in liver disease: studies using neutron activation analysis.
    Lancet (London, England), 1968, Dec-21, Volume: 2, Issue:7582

    Topics: Activation Analysis; Biliary Tract Diseases; Biopsy; Chemical and Drug Induced Liver Injury; Cholest

1968
Diagnosis of Wilson's disease in children with liver disease. A report of two families.
    Lancet (London, England), 1969, Jan-04, Volume: 1, Issue:7584

    Topics: Adolescent; Adult; Brain; Ceruloplasmin; Child; Copper; Diagnosis, Differential; Eye Manifestations;

1969
[D-penicillamine therapy in liver diseases. Preliminary results in 44 cases].
    MMW, Munchener medizinische Wochenschrift, 1974, Feb-01, Volume: 116, Issue:5

    Topics: Adult; Aged; Chronic Disease; Female; Hepatitis; Humans; Leukopenia; Liver Cirrhosis; Liver Diseases

1974
[Penicillamine therapy of chronic liver diseases].
    MMW, Munchener medizinische Wochenschrift, 1974, Feb-01, Volume: 116, Issue:5

    Topics: Azathioprine; Chronic Disease; Drug Hypersensitivity; Female; Glucocorticoids; Hepatitis; Humans; Li

1974
D-penicillamine in reconstructice surgery of the biliary tract.
    MMW, Munchener medizinische Wochenschrift, 1974, Dec-13, Volume: 116, Issue:50

    Topics: Biliary Tract Surgical Procedures; Cholestasis; Chronic Disease; Hepatitis; Liver Cirrhosis; Liver C

1974
[Long-term treatment of chronic aggressive hepatitis and liver cirrhosis using immunosuppressive agents].
    Die Medizinische Welt, 1974, Sep-27, Volume: 25, Issue:39

    Topics: Adrenal Cortex Hormones; Alanine Transaminase; Aspartate Aminotransferases; Azathioprine; Chronic Di

1974
[Acute hemolysis in morbus Wilson (author's transl)].
    Zeitschrift fur Kinderheilkunde, 1974, Volume: 118, Issue:2

    Topics: Adolescent; Adult; Anemia, Hemolytic; Ascites; Bilirubin; Blood Coagulation Tests; Blood Protein Ele

1974
[Immunoprevention and immunosuppression of chronic inflammatory liver diseases].
    Die Medizinische Welt, 1974, Oct-04, Volume: 25, Issue:40

    Topics: Adrenal Cortex Hormones; Antineoplastic Agents; Chronic Disease; Drug Therapy, Combination; Hepatiti

1974
[Nature of course and rehabilitation in the clinical stage of Wilson's disease].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1974, Volume: 26, Issue:11

    Topics: Adolescent; Adult; Age Factors; Basal Ganglia Diseases; Child; Child, Preschool; Diagnosis, Differen

1974
[Toward a control of collagen metabolism].
    Medecine & chirurgie digestives, 1974, Volume: 3, Issue:6

    Topics: Animals; Collagen; Female; Humans; Liver; Liver Cirrhosis; Liver Diseases; Male; Metabolism; Penicil

1974
Treatment of active chronic hepatitis and active cirrhosis with penicillamine.
    Postgraduate medical journal, 1974, Volume: 50 Suppl 2

    Topics: Azathioprine; Hepatitis; Humans; Liver Cirrhosis; Penicillamine

1974
[Mesenchyma-suppressing therapy of chronic aggressive hepatitis].
    Medizinische Klinik, 1972, Oct-06, Volume: 67, Issue:40

    Topics: Adolescent; Adult; Aged; Biopsy; Chronic Disease; Drug Hypersensitivity; Exanthema; Female; Gingival

1972
Penicillamine-induced cupriuria in normal subjects and in patients with active liver disease.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1973, Volume: 142, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aspartate Aminotransferases; Bilirubin; Cerulo

1973
Wilson's disease and pregnancy. A case report.
    Fertility and sterility, 1973, Volume: 24, Issue:6

    Topics: Abortion, Spontaneous; Adult; Ascites; Autopsy; Ceruloplasmin; Copper; Diet Therapy; Female; Fetus;

1973
[Effect of D-penicillamine on the collagen metabolism].
    Verhandlungen der Deutschen Gesellschaft fur Rheumatologie, 1974, Volume: 3, Issue:0

    Topics: Animals; Anti-Inflammatory Agents; Collagen; Connective Tissue; Disease Models, Animal; Liver; Liver

1974
[Treatment of chronic hepatitis].
    Zeitschrift fur arztliche Fortbildung, 1974, Volume: 68, Issue:5

    Topics: Azathioprine; Chronic Disease; Diet Therapy; Dietary Carbohydrates; Dietary Proteins; Female; Hepati

1974
Hemolytic anemia associated with Wilson's disease.
    The Journal of pediatrics, 1967, Volume: 71, Issue:2

    Topics: Adult; Anemia, Hemolytic; Ascites; Child; Copper; Cornea; Diet Therapy; Dimercaprol; Edetic Acid; Fe

1967
[Long term and permanent therapy of chronic hepatitis].
    Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:8

    Topics: Autoimmune Diseases; Chronic Disease; Cortisone; Cyclophosphamide; Female; Hepatitis; Hepatitis A; H

1970
[Therapy of active cirrhosis with penicillamine].
    Wiener medizinische Wochenschrift (1946), 1971, Dec-04, Volume: 121, Issue:49

    Topics: Acute Disease; Biopsy; Female; Humans; Liver Cirrhosis; Male; Middle Aged; Penicillamine

1971
[Therapy of the chronic aggressive hepatitis with D-penicillamine].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1971, Volume: 77

    Topics: Adult; Aged; Biopsy; Chronic Disease; Female; Hepatitis; Humans; Liver; Liver Cirrhosis; Male; Middl

1971
Penicillamine-induced normalization of clinical signs, and liver morphology and histochemistry in a case of Wilson's disease.
    Pediatrics, 1970, Volume: 45, Issue:2

    Topics: Ceruloplasmin; Child; Copper; Female; Hepatolenticular Degeneration; Histocytochemistry; Humans; Liv

1970
[Studies of the hepatolenticular degeneration and results of its continuous therapy].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1970, Volume: 30, Issue:1

    Topics: Acid Phosphatase; Adolescent; Adult; Alkaline Phosphatase; Blood Proteins; Chronic Disease; Depressi

1970
Renal function in Wilson's disease: response to penicillamine therapy.
    The American journal of the medical sciences, 1970, Volume: 260, Issue:6

    Topics: Adolescent; Adult; Aminohippuric Acids; Ammonium Chloride; Calcium; Dehydration; Female; Follow-Up S

1970
[The treatment of chronic aggressive hepatitis with D-penicillamine].
    Deutsche medizinische Wochenschrift (1946), 1971, Jan-22, Volume: 96, Issue:4

    Topics: Aged; Alanine Transaminase; Aspartate Aminotransferases; Bilirubin; Chronic Disease; Copper; Female;

1971
The varied manifestations of Wilson's disease.
    The Journal of pediatrics, 1971, Volume: 78, Issue:4

    Topics: Adolescent; Anemia, Hemolytic; Ascites; Ceruloplasmin; Child; Copper; Diseases in Twins; Eye Manifes

1971
Abnormalities of the physiology of copper in Wilson's disease. I. The whole-body turnover of copper.
    Archives of neurology, 1971, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Ascites; California; Ceruloplasmin; Child; Copper; Female; Hepatolenticular Degen

1971
[Anatomo-clinical study of a case of Wilson's disease treated with chelating agents for 5 years].
    Revue neurologique, 1968, Volume: 118, Issue:1

    Topics: Acute Kidney Injury; Adult; Basal Ganglia; Chelating Agents; Female; Globus Pallidus; Hepatolenticul

1968
[Hepatolenticular degeneration, Wilson's disease. A characteristics case with remission under penicillamine therapy].
    Ugeskrift for laeger, 1969, Jul-31, Volume: 131, Issue:31

    Topics: Adolescent; Adult; Female; Hepatolenticular Degeneration; Humans; Liver Cirrhosis; Penicillamine; Ti

1969