penicillamine has been researched along with Liver Cirrhosis, Biliary in 116 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Liver Cirrhosis, Biliary: FIBROSIS of the hepatic parenchyma due to obstruction of BILE flow (CHOLESTASIS) in the intrahepatic or extrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC; BILE DUCTS, EXTRAHEPATIC). Primary biliary cholangitis involves the destruction of small intra-hepatic bile ducts and decreased bile secretion. Secondary biliary cholangitis is produced by prolonged obstruction of large intrahepatic or extrahepatic bile ducts from a variety of causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A total of 227 patients with histologically advanced primary biliary cirrhosis entered a double-blind, randomized, controlled trial to determine whether penicillamine (1 g per day) was therapeutically effective; 111 patients received the drug, and 116 received placebo." | 9.05 | Trial of penicillamine in advanced primary biliary cirrhosis. ( Baldus, WP; Dickson, ER; Fleming, CR; Fleming, TR; Ludwig, J; McCall, JT; Wiesner, RH, 1985) |
| "The copper-chelating, immunological, and antifibrotic effects of D-penicillamine indicated that it might be suitable for the treatment of primary biliary cirrhosis (PBC)." | 9.05 | D-penicillamine treatment improves survival in primary biliary cirrhosis. ( Boss, AM; Cook, DG; Epstein, O; Jain, S; Lee, RG; Scheuer, PJ; Sherlock, S, 1981) |
| "One hundred and eighty nine patients with primary biliary cirrhosis were entered into a double blind, placebo controlled randomised trial starting in January 1978 to assess the therapeutic value of d-penicillamine 1200 mg daily." | 9.05 | Double blind controlled trial of d-penicillamine in patients with primary biliary cirrhosis. ( Caballeria, J; Christensen, E; Neuberger, J; Portmann, B; Ranek, L; Rodes, J; Tygstrup, N; Williams, R, 1985) |
| "A small double-blind controlled trial to evaluate the short-term effects of D-penicillamine therapy was carried out in 24 patients with primary biliary cirrhosis (PBC)." | 9.05 | Low therapeutic value of D-penicillamine in a short-term prospective trial in primary biliary cirrhosis. ( Brandt, KH; Schalm, SW; Taal, BG; Ten Kate, FW; Van Berge Henegouwen, GP, 1983) |
| "Six patients with primary biliary cirrhosis experienced lichen planus-like lesions while taking penicillamine." | 9.05 | Lichen planus-like lesions caused by penicillamine in primary biliary cirrhosis. ( Dickson, ER; Fleming, CR; Rogers, RS; Seehafer, JR, 1981) |
| "Although penicillamine is used in the treatment of primary biliary cirrhosis, its mechanism of action in this disease is unknown." | 9.05 | Effects of penicillamine on serum immunoglobulins and immune complex-reactive material in primary biliary cirrhosis. ( Bodenheimer, HC; Charland, C; Schaffner, F; Staples, PJ; Thayer, WR, 1985) |
| "We evaluated D-penicillamine in the treatment of primary biliary cirrhosis." | 9.05 | A prospective trial of D-penicillamine in primary biliary cirrhosis. ( Alpert, E; Kaplan, MM; Matloff, DS; Resnick, RH, 1982) |
| "Of 103 patients with the syndrome of primary biliary cirrhosis (chronic, nonsuppurative destructive cholangitis) who entered a double-blind, randomized, controlled treatment trial with either D-penicillamine or placebo, 21 (20%) were asymptomatic with respect to their liver disease." | 9.04 | Asymptomatic primary biliary cirrhosis. Presentation, histology, and results with D-penicillamine. ( Dickson, ER; Fleming, CR; Ludwig, J, 1978) |
| "D-penicillamine, 900 mg daily, was used in a randomised controlled trial for treatment of patients with primary biliary cirrhosis." | 9.04 | A controlled trial of D-penicillamine therapy in primary biliary cirrhosis. ( Jain, S; McGee, JO; Samourian, S; Scheuer, PJ, 1977) |
| "D-Penicillamine is used for patients with primary biliary cirrhosis due to its ability to decrease hepatic copper and modulate the immune response." | 8.83 | Systematic review and meta-analysis: D-Penicillamine vs. placebo/no intervention in patients with primary biliary cirrhosis--Cochrane Hepato-Biliary Group. ( Gluud, C; Gong, Y; Klingenberg, SL, 2006) |
| "D-penicillamine is used for patients with primary biliary cirrhosis due to its hepatic copper decreasing and immunomodulatory potentials." | 8.82 | D-penicillamine for primary biliary cirrhosis. ( Frederiksen, SL; Gluud, C; Gong, Y, 2004) |
| "25 serum samples of 22 patients with primary biliary cirrhosis (15 under or after treatment with D-penicillamine) were tested for antibodies against D-penicillamine." | 7.68 | [Antibodies against D-penicillamine in primary biliary cirrhosis]. ( Storch, W, 1990) |
| "Although there is good evidence that D-penicillamine can induce polymyositis, the exact pathogenic mechanism remains unclear." | 7.68 | Polymyositis complicating D-penicillamine treatment. ( Asherson, RA; Aydintug, AO; Cervera, R; D'Cruz, D; Hughes, GR; Khamashta, MA; Ramírez, G, 1991) |
| "Platelet function was assessed in 28 patients with primary biliary cirrhosis (PBC), of whom 10 were receiving D-penicillamine." | 7.67 | Platelet aggregation and thromboxane A2 release in primary biliary cirrhosis and effect of D-penicillamine treatment. ( Barradas, MA; Dandona, P; Epstein, O; Fonseca, V; Hutton, RA; Jeremy, JY; McIntyre, N; Mikhailidis, DP, 1988) |
| "A 36-yr-old woman with primary biliary cirrhosis developed a Goodpasture's-like syndrome while on D-penicillamine treatment." | 7.66 | D-Penicillamine-induced Goodpasture's-like syndrome in primary biliary cirrhosis--successful treatment with plasmapheresis and immunosuppressives. ( Kaplan, MM; Matloff, DS, 1980) |
| "Ursodeoxycholic acid (UDCA) is a beneficial medical therapy for patients with PBC." | 6.69 | Long-term ursodeoxycholic acid delays histological progression in primary biliary cirrhosis. ( Angulo, P; Batts, KP; Dickson, ER; Jorgensen, RA; Lindor, KD; Therneau, TM, 1999) |
| "We report a patient with primary biliary cirrhosis, who developed polymyositis while receiving D-penicillamine therapy." | 5.29 | A case of polymyositis in a patient with primary biliary cirrhosis treated with D-penicillamine. ( Ahn, JH; Kim, TH; Peck, KR; Song, YW, 1993) |
| "In primary biliary cirrhosis there are increased skin pigmentation, hepatic fibrosis, elevated cholesterol and alkaline phosphatase levels, defective T lymphocytes and hyperactive B lymphocytes." | 5.26 | The pineal and regulation of fibrosis: pinealectomy as a model of primary biliary cirrhosis: roles of melatonin and prostaglandins in fibrosis and regulation of T lymphocytes. ( Cunnane, SC; Horrobin, DF; Manku, MS, 1979) |
| "Although penicillamine is used in the treatment of primary biliary cirrhosis, its mechanism of action in this disease is unknown." | 5.05 | Effects of penicillamine on serum immunoglobulins and immune complex-reactive material in primary biliary cirrhosis. ( Bodenheimer, HC; Charland, C; Schaffner, F; Staples, PJ; Thayer, WR, 1985) |
| "One hundred and eighty nine patients with primary biliary cirrhosis were entered into a double blind, placebo controlled randomised trial starting in January 1978 to assess the therapeutic value of d-penicillamine 1200 mg daily." | 5.05 | Double blind controlled trial of d-penicillamine in patients with primary biliary cirrhosis. ( Caballeria, J; Christensen, E; Neuberger, J; Portmann, B; Ranek, L; Rodes, J; Tygstrup, N; Williams, R, 1985) |
| "The copper-chelating, immunological, and antifibrotic effects of D-penicillamine indicated that it might be suitable for the treatment of primary biliary cirrhosis (PBC)." | 5.05 | D-penicillamine treatment improves survival in primary biliary cirrhosis. ( Boss, AM; Cook, DG; Epstein, O; Jain, S; Lee, RG; Scheuer, PJ; Sherlock, S, 1981) |
| "A small double-blind controlled trial to evaluate the short-term effects of D-penicillamine therapy was carried out in 24 patients with primary biliary cirrhosis (PBC)." | 5.05 | Low therapeutic value of D-penicillamine in a short-term prospective trial in primary biliary cirrhosis. ( Brandt, KH; Schalm, SW; Taal, BG; Ten Kate, FW; Van Berge Henegouwen, GP, 1983) |
| "Six patients with primary biliary cirrhosis experienced lichen planus-like lesions while taking penicillamine." | 5.05 | Lichen planus-like lesions caused by penicillamine in primary biliary cirrhosis. ( Dickson, ER; Fleming, CR; Rogers, RS; Seehafer, JR, 1981) |
| "We evaluated D-penicillamine in the treatment of primary biliary cirrhosis." | 5.05 | A prospective trial of D-penicillamine in primary biliary cirrhosis. ( Alpert, E; Kaplan, MM; Matloff, DS; Resnick, RH, 1982) |
| "A total of 227 patients with histologically advanced primary biliary cirrhosis entered a double-blind, randomized, controlled trial to determine whether penicillamine (1 g per day) was therapeutically effective; 111 patients received the drug, and 116 received placebo." | 5.05 | Trial of penicillamine in advanced primary biliary cirrhosis. ( Baldus, WP; Dickson, ER; Fleming, CR; Fleming, TR; Ludwig, J; McCall, JT; Wiesner, RH, 1985) |
| "D-penicillamine, 900 mg daily, was used in a randomised controlled trial for treatment of patients with primary biliary cirrhosis." | 5.04 | A controlled trial of D-penicillamine therapy in primary biliary cirrhosis. ( Jain, S; McGee, JO; Samourian, S; Scheuer, PJ, 1977) |
| "Of 103 patients with the syndrome of primary biliary cirrhosis (chronic, nonsuppurative destructive cholangitis) who entered a double-blind, randomized, controlled treatment trial with either D-penicillamine or placebo, 21 (20%) were asymptomatic with respect to their liver disease." | 5.04 | Asymptomatic primary biliary cirrhosis. Presentation, histology, and results with D-penicillamine. ( Dickson, ER; Fleming, CR; Ludwig, J, 1978) |
| "As part of a double blind, randomized trial evaluating D-penicillamine in primary biliary cirrhosis, we monitored urinary copper excretion and hepatic copper concentration during the 1st year of therapy in 46 patients with this disease." | 5.04 | Effect of D-penicillamine on copper retention in patients with primary billiary cirrhosis. ( Baggenstoss, AH; Deering, TB; Dickson, ER; Fleming, CR; Geall, MG; McCall, JT, 1977) |
| "D-Penicillamine is used for patients with primary biliary cirrhosis due to its ability to decrease hepatic copper and modulate the immune response." | 4.83 | Systematic review and meta-analysis: D-Penicillamine vs. placebo/no intervention in patients with primary biliary cirrhosis--Cochrane Hepato-Biliary Group. ( Gluud, C; Gong, Y; Klingenberg, SL, 2006) |
| "D-penicillamine is used for patients with primary biliary cirrhosis due to its hepatic copper decreasing and immunomodulatory potentials." | 4.82 | D-penicillamine for primary biliary cirrhosis. ( Frederiksen, SL; Gluud, C; Gong, Y, 2004) |
| "Although there is good evidence that D-penicillamine can induce polymyositis, the exact pathogenic mechanism remains unclear." | 3.68 | Polymyositis complicating D-penicillamine treatment. ( Asherson, RA; Aydintug, AO; Cervera, R; D'Cruz, D; Hughes, GR; Khamashta, MA; Ramírez, G, 1991) |
| "25 serum samples of 22 patients with primary biliary cirrhosis (15 under or after treatment with D-penicillamine) were tested for antibodies against D-penicillamine." | 3.68 | [Antibodies against D-penicillamine in primary biliary cirrhosis]. ( Storch, W, 1990) |
| "Platelet function was assessed in 28 patients with primary biliary cirrhosis (PBC), of whom 10 were receiving D-penicillamine." | 3.67 | Platelet aggregation and thromboxane A2 release in primary biliary cirrhosis and effect of D-penicillamine treatment. ( Barradas, MA; Dandona, P; Epstein, O; Fonseca, V; Hutton, RA; Jeremy, JY; McIntyre, N; Mikhailidis, DP, 1988) |
| "The prevalence of autoimmune associations was determined in 113 patients with primary biliary cirrhosis who participated in a therapeutic trial of D-penicillamine." | 3.66 | Autoimmune associations in primary biliary cirrhosis. ( Baldus, WP; Culp, KS; Dickson, ER; Duffy, J; Fleming, CR, 1982) |
| "A 36-yr-old woman with primary biliary cirrhosis developed a Goodpasture's-like syndrome while on D-penicillamine treatment." | 3.66 | D-Penicillamine-induced Goodpasture's-like syndrome in primary biliary cirrhosis--successful treatment with plasmapheresis and immunosuppressives. ( Kaplan, MM; Matloff, DS, 1980) |
| "Ursodeoxycholic acid (UDCA) is a beneficial medical therapy for patients with PBC." | 2.69 | Long-term ursodeoxycholic acid delays histological progression in primary biliary cirrhosis. ( Angulo, P; Batts, KP; Dickson, ER; Jorgensen, RA; Lindor, KD; Therneau, TM, 1999) |
| "Primary sclerosing cholangitis and primary biliary cirrhosis are chronic cholestatic syndromes that may be difficult to differentiate clinically." | 2.66 | Comparison of the clinicopathologic features of primary sclerosing cholangitis and primary biliary cirrhosis. ( Dickson, ER; LaRusso, NF; Ludwig, J; Wiesner, RH, 1985) |
| "In this subset of patients with primary biliary cirrhosis, a significantly higher prevalence (86 percent) of circulating immune complexes was detected compared with those patients showing no autoimmune features (60 percent)." | 2.65 | Immune complexes in primary biliary cirrhosis. Higher prevalence of circulating immune complexes in patients with associated autoimmune features. ( Baggenstoss, AH; Dickson, ER; Gupta, RC; McDuffie, FC, 1982) |
| "Lichen planus and primary biliary cirrhosis were seen in twenty-four patients." | 2.65 | Primary biliary cirrhosis and lichen planus. ( Dickson, ER; Powell, FC; Rogers, RS, 1983) |
| "Ursodeoxycholic acid has been shown to improve survival free of transplantation in a conclusive fashion." | 2.40 | Management of primary biliary cirrhosis and autoimmune cholangitis. ( Angulo, P; Lindor, KD, 1998) |
| "Primary biliary cirrhosis is a disease of the small bile ducts with altered immunologic responsiveness often associated with various collagen diseases." | 2.36 | Primary biliary cirrhosis as a collagen disease. ( Schaffner, F, 1979) |
| "Primary biliary cirrhosis is a disease where small intra-hepatic bile ducts are destroyed as a result of an immunological reaction, presumably by cytotoxic T-lymphocytes on biliary epithelium." | 2.36 | Primary biliary cirrhosis: critical evaluation and treatment policies. ( Sherlock, S, 1982) |
| "We report a patient with primary biliary cirrhosis, who developed polymyositis while receiving D-penicillamine therapy." | 1.29 | A case of polymyositis in a patient with primary biliary cirrhosis treated with D-penicillamine. ( Ahn, JH; Kim, TH; Peck, KR; Song, YW, 1993) |
| "Data from 73 asymptomatic patients with primary biliary cirrhosis were analyzed to determine clinical course and long-term survival." | 1.28 | Diminished survival in asymptomatic primary biliary cirrhosis. A prospective study. ( Balasubramaniam, K; Dickson, ER; Grambsch, PM; Lindor, KD; Wiesner, RH, 1990) |
| "Ten patients with primary biliary cirrhosis (PBC) were clinically followed under the conditions of follow-up care." | 1.27 | [Clinical-dispensary finding of patients with primary biliary cirrhosis]. ( Bakalov, V; Chernev, K, 1985) |
| "Thus most patients with primary biliary cirrhosis have increased pancreatic enzyme activity and immunoreactive trypsin concentration in their sera." | 1.27 | Serum immunoreactive trypsin and pancreatic lipase in primary biliary cirrhosis. ( Dandona, P; Epstein, O; Fonseca, V; Junglee, D; Katrak, A; McIntyre, N; Mikhailidis, DP, 1986) |
| "The previously unreported occurrence of primary biliary cirrhosis with cold autoimmune hemolytic anemia is described." | 1.26 | Primary biliary cirrhosis and cold autoimmune hemolytic anemia: effect of partial plasma exchange. ( Berkman, EM; Kaplan, MM; Matloff, DS; Orlin, JB, 1980) |
| "In primary biliary cirrhosis there are increased skin pigmentation, hepatic fibrosis, elevated cholesterol and alkaline phosphatase levels, defective T lymphocytes and hyperactive B lymphocytes." | 1.26 | The pineal and regulation of fibrosis: pinealectomy as a model of primary biliary cirrhosis: roles of melatonin and prostaglandins in fibrosis and regulation of T lymphocytes. ( Cunnane, SC; Horrobin, DF; Manku, MS, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 83 (71.55) | 18.7374 |
| 1990's | 14 (12.07) | 18.2507 |
| 2000's | 9 (7.76) | 29.6817 |
| 2010's | 9 (7.76) | 24.3611 |
| 2020's | 1 (0.86) | 2.80 |
| Authors | Studies |
|---|---|
| Shan, G | 1 |
| Lu, B | 1 |
| Cai, D | 1 |
| Tong, X | 1 |
| Wey, A | 1 |
| Wang, L | 1 |
| Rudser, K | 1 |
| Shen, C | 1 |
| Li, X | 1 |
| Li, L | 1 |
| Bartolucci, F | 1 |
| Farcomeni, A | 1 |
| Zhu, GQ | 1 |
| Huang, S | 1 |
| Huang, GQ | 1 |
| Wang, LR | 1 |
| Lin, YQ | 1 |
| Wu, YM | 1 |
| Shi, KQ | 1 |
| Wang, JT | 1 |
| Zhou, ZR | 1 |
| Braddock, M | 1 |
| Chen, YP | 1 |
| Zhou, MT | 1 |
| Zheng, MH | 1 |
| Wu, J | 1 |
| Xiong, X | 1 |
| Su, X | 1 |
| Zhou, T | 1 |
| Yan, X | 1 |
| Fan, J | 1 |
| Yang, S | 1 |
| Kahan, BC | 1 |
| Morris, TP | 1 |
| Tian, L | 1 |
| Cai, T | 1 |
| Zhao, L | 1 |
| Wei, LJ | 1 |
| Saha-Chaudhuri, P | 1 |
| Heagerty, PJ | 2 |
| McCann, P | 1 |
| Pramanik, A | 1 |
| Gong, Y | 2 |
| Frederiksen, SL | 1 |
| Gluud, C | 2 |
| Angulo, P | 3 |
| Lindor, KD | 5 |
| Carter, RE | 1 |
| Lipsitz, SR | 1 |
| Tilley, BC | 1 |
| Zheng, Y | 1 |
| Xie, J | 1 |
| Liu, C | 1 |
| Klingenberg, SL | 1 |
| Epstein, O | 8 |
| Jain, S | 3 |
| Lee, RG | 1 |
| Cook, DG | 1 |
| Boss, AM | 1 |
| Scheuer, PJ | 2 |
| Sherlock, S | 6 |
| Lesna, M | 1 |
| Powell, FC | 3 |
| Rogers, RS | 4 |
| Rebora, A | 1 |
| Müting, D | 1 |
| Fischer, R | 1 |
| Kalk, JF | 1 |
| Kruck, P | 1 |
| Paumgartner, G | 1 |
| Triger, DR | 1 |
| Dickson, ER | 14 |
| Rull, S | 1 |
| Rodríguez-San Román, JL | 1 |
| Velilla, JP | 1 |
| Taal, BG | 3 |
| Schalm, SW | 4 |
| Ten Kate, FW | 1 |
| Van Berge Henegouwen, GP | 2 |
| Brandt, KH | 2 |
| Seehafer, JR | 1 |
| Fleming, CR | 6 |
| Thomas, HC | 2 |
| Brown, D | 1 |
| Labrooy, J | 1 |
| Tittor, W | 1 |
| Savolainen, ER | 1 |
| Miettinen, TA | 2 |
| Pikkarainen, P | 2 |
| Salaspuro, MP | 2 |
| Kivirikko, KI | 1 |
| Culp, KS | 1 |
| Duffy, J | 1 |
| Baldus, WP | 2 |
| Willson, RA | 1 |
| Fernandes, L | 1 |
| Berry, H | 1 |
| Hamilton, E | 1 |
| Matloff, DS | 3 |
| Alpert, E | 1 |
| Resnick, RH | 2 |
| Kaplan, MM | 6 |
| Reed, M | 1 |
| Jones, EA | 1 |
| Vierling, JM | 1 |
| Le Bihan, G | 1 |
| Birembaut, JC | 1 |
| Bourreille, J | 1 |
| Ueda, A | 1 |
| Miyanaga, O | 1 |
| Ishibashi, H | 1 |
| Okubo, H | 1 |
| Gupta, RC | 1 |
| McDuffie, FC | 1 |
| Baggenstoss, AH | 2 |
| Rosen, R | 1 |
| Theodor, E | 1 |
| Mörl, M | 2 |
| Scott, J | 1 |
| Jenkins, W | 1 |
| Smith, GP | 1 |
| Peters, TJ | 1 |
| Ward, K | 1 |
| Weir, DG | 1 |
| Mansurov, KhKh | 1 |
| Mirodzhov, GK | 1 |
| Ladnaia, MM | 1 |
| Sullivan, AL | 1 |
| Burakoff, R | 1 |
| Weintraub, LR | 1 |
| Sipponen, P | 1 |
| Vuori, E | 1 |
| Orlin, JB | 1 |
| Berkman, EM | 1 |
| Jenss, H | 1 |
| Ahn, JH | 1 |
| Kim, TH | 1 |
| Peck, KR | 1 |
| Song, YW | 1 |
| Locke, GR | 1 |
| Therneau, TM | 3 |
| Ludwig, J | 6 |
| Karrison, TG | 1 |
| Chuah, SY | 1 |
| Wong, NW | 1 |
| Goh, KL | 1 |
| Faraggi, D | 1 |
| Simon, R | 1 |
| Batts, KP | 2 |
| Jorgensen, RA | 1 |
| Larson, DR | 1 |
| LaRusso, NF | 2 |
| King, TS | 1 |
| Chinchilli, VM | 1 |
| Tazi, KA | 1 |
| Barrière, E | 1 |
| Moreau, R | 1 |
| Poirel, O | 1 |
| Lebrec, D | 1 |
| Samourian, S | 1 |
| McGee, JO | 1 |
| Gottfried, DJ | 1 |
| McDonald, GS | 1 |
| Elveback, LR | 1 |
| McCall, JT | 3 |
| Cunnane, SC | 1 |
| Manku, MS | 1 |
| Horrobin, DF | 1 |
| Schaffner, F | 2 |
| Soltis, RD | 1 |
| Wilson, ID | 1 |
| Thomas, H | 1 |
| Ahmed, N | 1 |
| DeCoux, R | 1 |
| Thompson, FA | 1 |
| Achord, JL | 1 |
| Scott, LD | 1 |
| De Villiers, D | 1 |
| Potter, BJ | 1 |
| Deering, TB | 1 |
| Geall, MG | 1 |
| Beukers, R | 1 |
| van Zanten, RA | 1 |
| Berenguer Lapuerta, J | 1 |
| Nos Mateu, P | 1 |
| Siles Moreno, MS | 1 |
| Aydintug, AO | 1 |
| Cervera, R | 1 |
| D'Cruz, D | 1 |
| Ramírez, G | 1 |
| Asherson, RA | 1 |
| Khamashta, MA | 1 |
| Hughes, GR | 1 |
| Storch, W | 1 |
| Balasubramaniam, K | 1 |
| Grambsch, PM | 1 |
| Wiesner, RH | 3 |
| Christensen, E | 3 |
| Neuberger, J | 2 |
| Altman, DG | 1 |
| Polson, R | 1 |
| Buckels, J | 1 |
| Rolles, K | 1 |
| Elias, E | 2 |
| Calne, R | 1 |
| McMaster, P | 1 |
| Williams, R | 2 |
| Chernev, K | 1 |
| Bakalov, V | 1 |
| Mikhailidis, DP | 2 |
| Fonseca, V | 2 |
| Barradas, MA | 1 |
| Hutton, RA | 1 |
| Jeremy, JY | 1 |
| McIntyre, N | 2 |
| Dandona, P | 2 |
| Adams, D | 1 |
| Clements, D | 1 |
| Graham-Brown, RA | 1 |
| Sarkany, I | 1 |
| Katrak, A | 1 |
| Junglee, D | 1 |
| Shimizu, H | 1 |
| Takahashi, M | 1 |
| Kurihara, T | 1 |
| Tomizawa, T | 1 |
| Shimomura, Y | 1 |
| Takezawa, J | 1 |
| Kobayashi, I | 1 |
| Kobayashi, S | 1 |
| Bassendine, MF | 1 |
| Dewar, PJ | 1 |
| James, OF | 2 |
| Bodenheimer, HC | 1 |
| Charland, C | 1 |
| Thayer, WR | 1 |
| Staples, PJ | 1 |
| Portmann, B | 1 |
| Caballeria, J | 1 |
| Rodes, J | 1 |
| Ranek, L | 1 |
| Tygstrup, N | 1 |
| Fleming, TR | 1 |
| Smithgall, JM | 1 |
| Roll, J | 1 |
| Warnes, TW | 1 |
| Weismann, K | 1 |
| Wantzin, GL | 1 |
| James, SP | 1 |
| Gibson, LE | 1 |
| Dicken, CH | 1 |
| Smallwood, RA | 1 |
| Williams, HA | 1 |
| Rosenoer, VM | 1 |
| Henrich, M | 1 |
| Leeson, PM | 1 |
| Fourman, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized Controlled Trial To Assess Risk of Delirium in Older Adults Undergoing Hip Fracture Surgery With Spinal or General Anesthesia[NCT02190903] | 15 participants (Actual) | Interventional | 2013-10-31 | Completed | |||
| An Adaptive, Randomized Phase II Trial to Determine Pathologic Complete Response With the Addition of Carboplatin With and Without Veliparib to Standard Chemotherapy in the Neoadjuvant Treatment of Triple-Negative Breast Cancer[NCT01818063] | Phase 2 | 9 participants (Actual) | Interventional | 2013-04-25 | Completed | ||
| Ependymomics: Multiomic Approach to Radioresistance of Ependymomas in Children and Adolescents[NCT05151718] | 370 participants (Anticipated) | Observational | 2021-09-30 | Recruiting | |||
| Efficacy and Security of Bezafibrate in Patients With Primary Biliary Cirrhosis Without Biochemical Response to Ursodeoxycholic Acid: A Randomized, Double-blind, Placebo-controlled Trial[NCT02937012] | Phase 3 | 34 participants (Anticipated) | Interventional | 2016-10-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Delirium will be assessed by the Confusion Assessment Method Instrument (CAM), a validated method of assessing delirium based on the presence of both (1) an acute onset of signs and symptoms with a fluctuating course AND (2) inattention; PLUS (3) disorganized thinking OR (4) an altered level of consciousness. (NCT02190903)
Timeframe: Up to 5 days post hip fracture surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| General Endotracheal Anesthesia | 2 |
| Regional (Spinal) Anesthesia | 0 |
PCR is defined as the absence of any residual invasive cancer on hematoxylin and eosin (H&E) evaluation of the resected breast specimen and all sampled ipsilateral lymph nodes. (NCT01818063)
Timeframe: 36 months following surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Arm 1 (Paclitaxel, Carboplatin) | 3 |
| Arm 2 (Veliparib, Paclitaxel, Carboplatin) | 3 |
22 reviews available for penicillamine and Liver Cirrhosis, Biliary
| Article | Year |
|---|---|
Optimal drug regimens for primary biliary cirrhosis: a systematic review and network meta-analysis.
Topics: Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Bezafibrate; Bile Ducts; Colchicine; Cyclosporin | 2015 |
D-penicillamine for primary biliary cirrhosis.
Topics: Chelating Agents; Humans; Liver Cirrhosis, Biliary; Penicillamine; Randomized Controlled Trials as T | 2004 |
Management of primary biliary cirrhosis and autoimmune cholangitis.
Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Cholangitis; Colchicine; Disease Progression; Drug The | 1998 |
Systematic review and meta-analysis: D-Penicillamine vs. placebo/no intervention in patients with primary biliary cirrhosis--Cochrane Hepato-Biliary Group.
Topics: Chelating Agents; Female; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Penicillamine; Random | 2006 |
[Therapy of liver cirrhosis].
Topics: Adrenal Cortex Hormones; Azathioprine; Chronic Disease; Colchicine; Hepatitis; Humans; Liver Cirrhos | 1983 |
Primary biliary cirrhosis.
Topics: Aged; Antibodies; Antigen-Antibody Complex; Cholecalciferol; Copper; Humans; Immunoglobulin M; Liver | 1982 |
[Current aspects of primary biliary cirrhosis (2)].
Topics: Azathioprine; Biliary Tract Diseases; Cholestyramine Resin; Cyclosporins; Diagnosis, Differential; H | 1983 |
Primary biliary cirrhosis: critical evaluation and treatment policies.
Topics: Adrenal Cortex Hormones; Adult; Antibodies; Azathioprine; Copper; Female; Humans; Liver; Liver Cirrh | 1982 |
T cell subsets in autoimmune and HBV-induced chronic liver disease, HBs antigen carriers with normal histology and primary biliary cirrhosis: a review of the abnormalities and the effects of treatment.
Topics: Antibodies, Monoclonal; Autoimmune Diseases; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surfac | 1982 |
Primary biliary cirrhosis: a challenging disease for hepatologists and immunologists.
Topics: Azathioprine; Chlorambucil; Cholestyramine Resin; Copper; Cyclophosphamide; Female; Humans; Liver; L | 1981 |
Copper metabolism in primary biliary cirrhosis.
Topics: Adrenal Cortex Hormones; Bile; Ceruloplasmin; Copper; Diet; Estrogens; Homeostasis; Humans; Intestin | 1981 |
Treatment and prognosis of primary biliary cirrhosis.
Topics: Antigen-Antibody Complex; Azathioprine; Collagen; Copper; Cyclosporins; Humans; Liver; Liver Cirrhos | 1981 |
Primary biliary cirrhosis as a collagen disease.
Topics: Adrenal Cortex Hormones; Antibodies; Antigen-Antibody Complex; Aspirin; Collagen Diseases; Complemen | 1979 |
Primary biliary cirrhosis.
Topics: Adult; Aged; Antigen-Antibody Complex; Copper; Esophageal and Gastric Varices; Female; Humans; Liver | 1979 |
[The treatment of primary biliary cirrhosis. Its current status].
Topics: Adrenal Cortex Hormones; Colchicine; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Liv | 1991 |
Medical treatment of primary biliary cirrhosis.
Topics: Colchicine; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Methotrexate; Penicillamine; | 1989 |
Prognostication in primary biliary cirrhosis: relevance to the individual patient.
Topics: Azathioprine; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Models, Theoretical; Penicill | 1989 |
The treatment of primary biliary cirrhosis.
Topics: Adrenal Cortex Hormones; Antipruritics; Azathioprine; Celiac Disease; Chlorambucil; Colchicine; Cycl | 1986 |
Primary biliary cirrhosis. The present position.
Topics: Adult; Antibodies; Biopsy; Combined Modality Therapy; Female; Humans; Liver; Liver Cirrhosis, Biliar | 1986 |
Primary biliary cirrhosis.
Topics: Azathioprine; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Penicillamine | 1987 |
The copper-controlled diet: current aspects of dietary copper restriction in management of copper metabolism disorders.
Topics: Chelating Agents; Copper; Diet; Hepatolenticular Degeneration; Humans; Liver Cirrhosis, Biliary; Pen | 1985 |
Treatment of primary biliary cirrhosis.
Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Chlorambucil; Cholelithiasis; Colchicine | 1985 |
22 trials available for penicillamine and Liver Cirrhosis, Biliary
| Article | Year |
|---|---|
A discrete time event-history approach to informative drop-out in mixed latent Markov models with covariates.
Topics: Artifacts; Data Interpretation, Statistical; Humans; Liver Cirrhosis, Biliary; Markov Chains; Outcom | 2015 |
D-penicillamine treatment improves survival in primary biliary cirrhosis.
Topics: Antigen-Antibody Complex; Clinical Trials as Topic; Double-Blind Method; Humans; Liver Cirrhosis, Bi | 1981 |
Primary biliary cirrhosis and lichen planus.
Topics: Clinical Trials as Topic; Double-Blind Method; Graft vs Host Reaction; Humans; Lichen Planus; Liver | 1983 |
Low therapeutic value of D-penicillamine in a short-term prospective trial in primary biliary cirrhosis.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Liver Cirrhosis, Biliary; Male | 1983 |
Lichen planus-like lesions caused by penicillamine in primary biliary cirrhosis.
Topics: Clinical Trials as Topic; Double-Blind Method; Drug Eruptions; Female; Humans; Lichen Planus; Liver | 1981 |
Enzymes of collagen synthesis and type III procollagen aminopropeptide in the evaluation of D-penicillamine and medroxyprogesterone treatments of primary biliary cirrhosis.
Topics: Adult; Aged; Collagen; Female; Humans; Liver; Liver Cirrhosis, Biliary; Male; Medroxyprogesterone; M | 1983 |
A prospective trial of D-penicillamine in primary biliary cirrhosis.
Topics: Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Clinical Trials | 1982 |
Penicillamine therapy 'encouraging' in primary biliary cirrhosis study.
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Liver Cirrhosis, Biliary; Penicillamine | 1982 |
Immune complexes in primary biliary cirrhosis. Higher prevalence of circulating immune complexes in patients with associated autoimmune features.
Topics: Antigen-Antibody Complex; Autoantibodies; Autoimmune Diseases; Complement Activation; Humans; Liver | 1982 |
Time course of histological progression in primary biliary cirrhosis.
Topics: Biopsy; Disease Progression; Double-Blind Method; Female; Humans; Liver; Liver Cirrhosis, Biliary; M | 1996 |
Long-term ursodeoxycholic acid delays histological progression in primary biliary cirrhosis.
Topics: Adult; Aged; Cholagogues and Choleretics; Disease Progression; Female; Humans; Liver Cirrhosis; Live | 1999 |
A controlled trial of D-penicillamine therapy in primary biliary cirrhosis.
Topics: Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Clinical Trials as Topic; Copper; Drug | 1977 |
Asymptomatic primary biliary cirrhosis. Presentation, histology, and results with D-penicillamine.
Topics: Adult; Aged; Clinical Trials as Topic; Copper; Female; Humans; Liver; Liver Cirrhosis, Biliary; Live | 1978 |
Reduction of immune complexes and immunoglobulins induced by D-penicillamine in primary biliary cirrhosis.
Topics: Antigen-Antibody Complex; Aspartate Aminotransferases; Bilirubin; Complement System Proteins; Copper | 1979 |
Effect of D-penicillamine on copper retention in patients with primary billiary cirrhosis.
Topics: Ceruloplasmin; Copper; Humans; Liver; Liver Cirrhosis, Biliary; Penicillamine; Placebos | 1977 |
Comparison of the clinicopathologic features of primary sclerosing cholangitis and primary biliary cirrhosis.
Topics: Adult; Bile Ducts; Biopsy; Cholangiography; Cholangitis; Clinical Trials as Topic; Diagnosis, Differ | 1985 |
Effects of penicillamine on serum immunoglobulins and immune complex-reactive material in primary biliary cirrhosis.
Topics: Antigen-Antibody Complex; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Immunoglobu | 1985 |
D-penicillamine for primary biliary cirrhosis.
Topics: Clinical Trials as Topic; Humans; Liver Cirrhosis, Biliary; Penicillamine | 1985 |
Double blind controlled trial of d-penicillamine in patients with primary biliary cirrhosis.
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Liver Cirrhosis, Biliary; Penicillamine | 1985 |
Trial of penicillamine in advanced primary biliary cirrhosis.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Humans; Liver; Liver Cirrh | 1985 |
A new treatment for primary biliary cirrhosis?
Topics: Aged; Azathioprine; Clinical Trials as Topic; Humans; Liver Cirrhosis, Biliary; Liver Transplantatio | 1985 |
Cryoglobulins in primary biliary cirrhosis: prevalence and modulation by immunosuppressive therapy.
Topics: Adult; Aged; Alkaline Phosphatase; Autoantibodies; Autoimmune Diseases; Clinical Trials as Topic; Cr | 1985 |
72 other studies available for penicillamine and Liver Cirrhosis, Biliary
| Article | Year |
|---|---|
Two-stage optimal designs based on exact variance for a single-arm trial with survival endpoints.
Topics: Clinical Trials as Topic; Computer Simulation; Data Interpretation, Statistical; Humans; Liver Cirrh | 2020 |
Testing causal effects in observational survival data using propensity score matching design.
Topics: Bias; Biostatistics; Causality; Cohort Studies; Computer Simulation; Confounding Factors, Epidemiolo | 2018 |
Censored quantile regression with recursive partitioning-based weights.
Topics: Bilirubin; Computer Simulation; Humans; Kaplan-Meier Estimate; Liver Cirrhosis, Biliary; Models, Sta | 2014 |
Inverse probability weighting for covariate adjustment in randomized studies.
Topics: Computer Simulation; Data Interpretation, Statistical; Female; Humans; Liver Cirrhosis, Biliary; Mal | 2014 |
Survival trial design and monitoring using historical controls.
Topics: Double-Blind Method; Humans; Liver Cirrhosis, Biliary; Models, Statistical; Penicillamine; Randomize | 2016 |
Interaction trees with censored survival data.
Topics: Algorithms; Biostatistics; Endpoint Determination; Humans; Kaplan-Meier Estimate; Liver Cirrhosis, B | 2008 |
Improper analysis of trials randomised using stratified blocks or minimisation.
Topics: Antineoplastic Agents; Back Injuries; Bias; Breast Neoplasms; Carcinoma; Computer Simulation; Data I | 2012 |
On the covariate-adjusted estimation for an overall treatment difference with data from a randomized comparative clinical trial.
Topics: Analysis of Variance; Bias; Biostatistics; Data Interpretation, Statistical; Humans; Kaplan-Meier Es | 2012 |
Non-parametric estimation of a time-dependent predictive accuracy curve.
Topics: Area Under Curve; Biomarkers; Breast Neoplasms; Cell Cycle; Computer Simulation; Data Interpretation | 2013 |
Dysphagia and unexpected myasthenia gravis associated with primary biliary cirrhosis, ulcerative colitis and vitiligo.
Topics: Aged; Colitis, Ulcerative; Deglutition Disorders; Humans; Liver Cirrhosis, Biliary; Male; Myasthenia | 2004 |
Quasi-likelihood estimation for relative risk regression models.
Topics: Antibiotics, Antineoplastic; Humans; Likelihood Functions; Liver Cirrhosis, Biliary; Penicillamine; | 2005 |
Survival model predictive accuracy and ROC curves.
Topics: Biometry; Humans; Liver Cirrhosis, Biliary; Lung Neoplasms; Models, Statistical; Penicillamine; Pred | 2005 |
Survival model predictive accuracy and ROC curves.
Topics: Biometry; Humans; Liver Cirrhosis, Biliary; Lung Neoplasms; Models, Statistical; Penicillamine; Pred | 2005 |
Survival model predictive accuracy and ROC curves.
Topics: Biometry; Humans; Liver Cirrhosis, Biliary; Lung Neoplasms; Models, Statistical; Penicillamine; Pred | 2005 |
Survival model predictive accuracy and ROC curves.
Topics: Biometry; Humans; Liver Cirrhosis, Biliary; Lung Neoplasms; Models, Statistical; Penicillamine; Pred | 2005 |
Adjusted Kaplan-Meier estimator and log-rank test with inverse probability of treatment weighting for survival data.
Topics: Adult; Aged; Black People; Chlamydia Infections; Computer Simulation; Data Interpretation, Statistic | 2005 |
Role of copper in primary biliary cirrhosis.
Topics: Copper; Humans; Liver Cirrhosis, Biliary; Penicillamine | 1981 |
Primary biliary cirrhosis, penicillamine, and lichen planus.
Topics: Adult; Female; Humans; Lichen Planus; Liver Cirrhosis, Biliary; Middle Aged; Penicillamine | 1981 |
Lichen planus and the liver.
Topics: Aged; Female; Humans; Lichen Planus; Liver Cirrhosis, Biliary; Male; Middle Aged; Penicillamine | 1981 |
[Chronic destructive non-suppurating cholangitis].
Topics: Aged; Alkaline Phosphatase; Antibodies, Antinuclear; Autoantibodies; Cholestyramine Resin; Female; g | 1982 |
Lichen planus and liver disease.
Topics: Autoimmune Diseases; Chronic Disease; Female; Hepatitis, Chronic; Humans; Lichen Planus; Liver Cirrh | 1984 |
[Therapy of primary biliary cirrhosis].
Topics: Antilymphocyte Serum; Azathioprine; Humans; Liver Cirrhosis, Biliary; Nitroglycerin; Penicillamine; | 1980 |
Autoimmune associations in primary biliary cirrhosis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Autoimmune Diseases; Female; Humans; Immunoglobulins; Keratoconj | 1982 |
Therapeutic quandary: asymptomatic primary biliary cirrhosis associated with polymyositis.
Topics: Alkaline Phosphatase; Female; Histocompatibility Antigens Class II; Humans; Liver Cirrhosis, Biliary | 1981 |
Historical perspectives on penicillamine.
Topics: Animals; Chelating Agents; Chemical Phenomena; Chemistry; Hepatitis; Humans; Immunity; Lathyrism; Li | 1980 |
[Primary biliary cirrhosis and lupus: role of D-penicillamine?].
Topics: Aged; Female; Humans; Liver Cirrhosis, Biliary; Lupus Erythematosus, Systemic; Penicillamine | 1982 |
[A case of primary biliary cirrhosis treated with D-penicillamine (author's transl)].
Topics: Adult; Female; Humans; Immunoglobulin M; Liver Cirrhosis, Biliary; Penicillamine | 1982 |
Lichen planus, primary biliary cirrhosis and penicillamine.
Topics: Female; Humans; Lichen Planus; Liver Cirrhosis, Biliary; Penicillamine | 1982 |
[Primary biliary cirrhosis].
Topics: Adrenal Cortex Hormones; Adult; Drug Therapy, Combination; Female; Humans; Liver Cirrhosis, Biliary; | 1982 |
[Main characteristics of the treatment of liver cirrhosis].
Topics: Adolescent; Adult; Ascites; Bed Rest; Bloodletting; Child; Child, Preschool; Cholestyramine Resin; D | 1981 |
Hepatic organelle pathology in primary biliary cirrhosis and the response to low-dose D-penicillamine therapy.
Topics: Adult; Alkaline Phosphatase; Copper; Humans; Immunoglobulin M; Liver; Liver Cirrhosis, Biliary; Midd | 1981 |
Life threatening agranulocytosis and toxic epidermal necrolysis during low dose penicillamine therapy.
Topics: Agranulocytosis; Female; Humans; Liver Cirrhosis, Biliary; Middle Aged; Penicillamine; Stevens-Johns | 1981 |
[Treatment of chronic hepatitis and primary biliary liver cirrhosis with D-penicillamine].
Topics: Adult; Chronic Disease; Female; Hepatitis; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Peni | 1981 |
Sideroblastic anemia associated with penicillamine therapy.
Topics: Anemia, Sideroblastic; Female; Humans; Liver Cirrhosis, Biliary; Middle Aged; Penicillamine | 1981 |
Hepatic copper in primary biliary cirrhosis: biliary excretion and response to penicillamine treatment.
Topics: Adult; Aged; Bile; Bile Acids and Salts; Copper; Female; Humans; Liver; Liver Cirrhosis, Biliary; Ma | 1981 |
Studies in primary biliary cirrhosis.
Topics: Adult; Aged; Bile Ducts; Cryoglobulins; Drug Therapy, Combination; Female; Humans; Immunoglobulins; | 1981 |
Primary biliary cirrhosis and cold autoimmune hemolytic anemia: effect of partial plasma exchange.
Topics: Agglutinins; Anemia, Hemolytic, Autoimmune; Autoantibodies; Azathioprine; Cold Temperature; Erythroc | 1980 |
[Therapy of primary biliary cirrhosis].
Topics: Humans; Liver Cirrhosis, Biliary; Penicillamine | 1980 |
D-Penicillamine-induced Goodpasture's-like syndrome in primary biliary cirrhosis--successful treatment with plasmapheresis and immunosuppressives.
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Azathioprine; Female; Humans; Liver Cirrhosis, Bil | 1980 |
A case of polymyositis in a patient with primary biliary cirrhosis treated with D-penicillamine.
Topics: Autoimmune Diseases; Female; Humans; Liver Cirrhosis, Biliary; Middle Aged; Penicillamine; Polymyosi | 1993 |
Use of Irwin's restricted mean as an index for comparing survival in different treatment groups--interpretation and power considerations.
Topics: Antirheumatic Agents; Data Interpretation, Statistical; Double-Blind Method; Humans; Liver Cirrhosis | 1997 |
Lethargy in a patient with cirrhosis.
Topics: Female; Humans; Hyperthyroidism; Liver Cirrhosis, Biliary; Middle Aged; Myasthenia Gravis; Penicilla | 1997 |
Bayesian variable selection method for censored survival data.
Topics: Bayes Theorem; Biometry; Humans; Likelihood Functions; Linear Models; Liver Cirrhosis, Biliary; Peni | 1998 |
Time course of histological progression in primary sclerosing cholangitis.
Topics: Adolescent; Adult; Aged; Biopsy; Cholagogues and Choleretics; Cholangitis, Sclerosing; Disease Progr | 1999 |
A generalized concordance correlation coefficient for continuous and categorical data.
Topics: Computer Simulation; Confidence Intervals; Data Interpretation, Statistical; Edema; Female; Humans; | 2001 |
Relationship between protein kinase C alterations and nitric oxide overproduction in cirrhotic rat aortas.
Topics: Animals; Aorta, Thoracic; Down-Regulation; Enzyme Inhibitors; In Vitro Techniques; Liver Cirrhosis, | 2002 |
D-penicillamine in primary biliary cirrhosis.
Topics: Humans; Liver Cirrhosis, Biliary; Penicillamine | 1977 |
Penicillamine in primary biliary cirrhosis.
Topics: Adult; Drug Evaluation; Female; Follow-Up Studies; Humans; Liver Cirrhosis, Biliary; Liver Function | 1978 |
Copper stains and the syndrome of primary biliary cirrhosis. Evaluation of staining methods and their usefulness for diagnosis and trials of penicillamine treatment.
Topics: Adult; Copper; Histocytochemistry; Humans; Liver; Liver Cirrhosis, Biliary; Penicillamine; Rhodamine | 1979 |
The pineal and regulation of fibrosis: pinealectomy as a model of primary biliary cirrhosis: roles of melatonin and prostaglandins in fibrosis and regulation of T lymphocytes.
Topics: Animals; Colchicine; Glucocorticoids; Humans; Liver Cirrhosis, Biliary; Melatonin; Models, Biologica | 1979 |
Immune complexes and the treatment of biliary cirrhosis.
Topics: Humans; Liver Cirrhosis, Biliary; Penicillamine | 1979 |
Immune complexes and the treatment of biliary cirrhosis.
Topics: Antigen-Antibody Complex; Humans; Immunoglobulins; Liver Cirrhosis, Biliary; Penicillamine | 1979 |
Immune complexes and the treatment of biliary cirrhosis.
Topics: Antigen-Antibody Complex; Humans; Immunoglobulins; Liver Cirrhosis, Biliary; Penicillamine | 1979 |
Primary biliary cirrhosis (PBC).
Topics: Azathioprine; Chronic Disease; Diagnosis, Differential; Hepatitis; Humans; Liver Cirrhosis, Biliary; | 1979 |
Copper toxicity in primary biliary cirrhosis.
Topics: Copper; Humans; Liver; Liver Cirrhosis, Biliary; Penicillamine | 1978 |
[Current insights in the treatment of primary biliary cirrhosis].
Topics: Azathioprine; Copper; Humans; Liver Cirrhosis, Biliary; Osteomalacia; Penicillamine; Pruritus; Vitam | 1978 |
Serial determination of type III procollagen amino propeptide serum levels in patients with histologically progressive and non-progressive primary biliary cirrhosis.
Topics: Adult; Alkaline Phosphatase; Bilirubin; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up S | 1992 |
Polymyositis complicating D-penicillamine treatment.
Topics: Adult; Arthritis, Psoriatic; Female; Humans; Liver Cirrhosis, Biliary; Middle Aged; Myositis; Penici | 1991 |
[Antibodies against D-penicillamine in primary biliary cirrhosis].
Topics: Drug Hypersensitivity; Fluorescent Antibody Technique; Humans; Immunoglobulin G; Liver Cirrhosis, Bi | 1990 |
Diminished survival in asymptomatic primary biliary cirrhosis. A prospective study.
Topics: Adult; Aged; Bilirubin; Female; Follow-Up Studies; Humans; Liver; Liver Cirrhosis, Biliary; Male; Mi | 1990 |
Survival in asymptomatic primary biliary cirrhosis. Not as good as previously reported?
Topics: Humans; Liver Cirrhosis, Biliary; Penicillamine; Prognosis; Survival Rate | 1990 |
Prognosis after liver transplantation for primary biliary cirrhosis.
Topics: Bilirubin; Diuretics; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Penicillamine; Progno | 1989 |
[Clinical-dispensary finding of patients with primary biliary cirrhosis].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Bilirubin; Diagnosis, Differential; | 1985 |
Platelet aggregation and thromboxane A2 release in primary biliary cirrhosis and effect of D-penicillamine treatment.
Topics: Aged; Cholesterol; Female; Humans; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged | 1988 |
[Are there new aspects in the therapy of primary biliary cirrhosis?].
Topics: Azathioprine; Bile Acids and Salts; Bilirubin; Cyclosporins; Humans; Liver Cirrhosis, Biliary; Liver | 1986 |
Lichen sclerosus et atrophicus. With primary biliary cirrhosis and lichen planus.
Topics: Autoantibodies; Humans; Lichen Planus; Liver Cirrhosis, Biliary; Male; Middle Aged; Mitochondria; Pe | 1986 |
Serum immunoreactive trypsin and pancreatic lipase in primary biliary cirrhosis.
Topics: Age Factors; Aged; Female; Humans; Isoenzymes; Lipase; Liver Cirrhosis, Biliary; Male; Middle Aged; | 1986 |
[A case of asymptomatic primary biliary cirrhosis with granuloma accompanied by giant cell].
Topics: Adult; Female; Granuloma, Giant Cell; Humans; Liver Cirrhosis, Biliary; Penicillamine; Prognosis | 1986 |
HLA-DR antigens in primary biliary cirrhosis: lack of association.
Topics: Bilirubin; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Liver Cirrhosis, Biliary; | 1985 |
[Lichen planus in primary biliary cirrhosis treated with penicillamine].
Topics: Female; Humans; Lichen Planus; Liver Cirrhosis, Biliary; Middle Aged; Penicillamine | 1986 |
Primary biliary cirrhosis.
Topics: Humans; Liver Cirrhosis, Biliary; Penicillamine | 1985 |
Pemphigus erythematosus, primary biliary cirrhosis, and D-penicillamine: report of a case.
Topics: Adult; Biopsy; Female; Humans; Liver Cirrhosis, Biliary; Pemphigus; Penicillamine; Skin | 1985 |
Liver-copper levels in liver disease: studies using neutron activation analysis.
Topics: Activation Analysis; Biliary Tract Diseases; Biopsy; Chemical and Drug Induced Liver Injury; Cholest | 1968 |
D-penicillamine in reconstructice surgery of the biliary tract.
Topics: Biliary Tract Surgical Procedures; Cholestasis; Chronic Disease; Hepatitis; Liver Cirrhosis; Liver C | 1974 |
A disorder of copper metabolism treated with penicillamine in a patient with primary biliary cirrhosis and renal tubular acidosis.
Topics: Acidosis, Renal Tubular; Adult; Alkaline Phosphatase; Bilirubin; Celiac Disease; Ceruloplasmin; Coli | 1967 |