penicillamine has been researched along with Keloid in 7 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Keloid: A sharply elevated, irregularly shaped, progressively enlarging scar resulting from formation of excessive amounts of collagen in the dermis during connective tissue repair. It is differentiated from a hypertrophic scar (CICATRIX, HYPERTROPHIC) in that the former does not spread to surrounding tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Ten patients with massive keloids, resistant to conventional therapy by excision, grafting, and/or intralesional injection of steroids, have been treated by excising the keloid, grafting the defect, inducing lathyrism with Beta aminopropionitrile fumurate or penicillamine and administering colchicine." | 3.66 | Pharmacologic control of surface scarring in human beings. ( Peacock, EE, 1981) |
| "In other situations, as in the treatment of keloids, physicians may wish to introduce drugs known to reduce scar formation into the biologic environment in which wound healing ensues." | 1.26 | Wound healing: a review. IV. Systemic medications affecting wound healing. ( Pollack, SV, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Santiago, M | 1 |
| de Castro, DO | 1 |
| Costa, CA | 1 |
| Passos, ES | 1 |
| Paixão, A | 1 |
| Mayou, BJ | 1 |
| Pollack, SV | 1 |
| Peacock, EE | 1 |
| Mizutani, H | 1 |
| Taniguchi, H | 1 |
| Sakakura, T | 1 |
| Shimizu, M | 1 |
| Waki, EY | 1 |
| Crumley, RL | 1 |
| Jakowatz, JG | 1 |
| Moynahan, EJ | 1 |
1 trial available for penicillamine and Keloid
| Article | Year |
|---|---|
D-Penicillamine in the treatment of keloids.
Topics: Adolescent; Adult; Child; Child, Preschool; Clinical Trials as Topic; Ear, External; Humans; Keloid; | 1981 |
6 other studies available for penicillamine and Keloid
| Article | Year |
|---|---|
Keloidal scleroderma.
Topics: Adult; Antirheumatic Agents; Azathioprine; Female; Humans; Keloid; Penicillamine; Scleroderma, Diffu | 2004 |
Wound healing: a review. IV. Systemic medications affecting wound healing.
Topics: Adrenal Cortex Hormones; Aminopropionitrile; Animals; Anti-Inflammatory Agents; Anticoagulants; Anti | 1982 |
Pharmacologic control of surface scarring in human beings.
Topics: Adolescent; Adult; Aged; Aminopropionitrile; Child; Cicatrix; Colchicine; Drug Administration Schedu | 1981 |
Nodular scleroderma: focally increased tenascin expression differing from that in the surrounding scleroderma skin.
Topics: Adult; Biopsy; Cell Adhesion Molecules, Neuronal; Diagnosis, Differential; Extracellular Matrix Prot | 1995 |
Effects of pharmacologic agents on human keloids implanted in athymic mice. A pilot study.
Topics: Acetylcysteine; Adolescent; Adult; Animals; Colchicine; Female; Humans; Keloid; Male; Mice; Mice, Nu | 1991 |
Penicillamine in the treatment of morphoea and keloid in children.
Topics: Child; Female; Humans; Keloid; Male; Penicillamine; Scleroderma, Localized | 1974 |