Page last updated: 2024-11-07

penicillamine and Jaundice

penicillamine has been researched along with Jaundice in 15 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Jaundice: A clinical manifestation of HYPERBILIRUBINEMIA, characterized by the yellowish staining of the SKIN; MUCOUS MEMBRANE; and SCLERA. Clinical jaundice usually is a sign of LIVER dysfunction.

Research Excerpts

ExcerptRelevanceReference
"A 65 year old woman with rheumatoid arthritis developed marrow aplasia and jaundice owing to D-penicillamine treatment."7.67Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis. ( Caspi, D; Fishel, B; Tishler, M; Yaron, M, 1989)
"A 65 year old woman with rheumatoid arthritis developed marrow aplasia and jaundice owing to D-penicillamine treatment."3.67Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis. ( Caspi, D; Fishel, B; Tishler, M; Yaron, M, 1989)
"Her jaundice was increasing along with prolonged prothrombin time and low albumin."1.62Prolonged Jaundice in a Patient with Coexisting Hepatitis A Virus Infection and Wilson's Disease. ( Chowdhury, M; Ghosh, CK; Hasan, MA; Miah, AR; Miah, SA, 2021)
"Although Wilson's Disease is a treatable disorder, 9 of 15 cases referred with undiagnosed liver disease in the present series died in 3 to 53 days of admission."1.27Wilson's disease in childhood. Variability of clinical presentation. ( Ede, RJ; Mowat, AP; Nazer, H; Williams, R, 1983)
"Forty-nine children with Wilson's disease under the age of 15 were treated with D-penicillamine for 2 to 15 years."1.26Prognosis of Wilson's disease in childhood. ( Arima, M; Kitahara, T; Suzuki, Y; Takeshita, K; Yoshino, K, 1977)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199013 (86.67)18.7374
1990's1 (6.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Ghosh, CK1
Miah, SA1
Hasan, MA1
Chowdhury, M1
Miah, AR1
Matek, W1
Rösch, W1
Becker, V1
Nazer, H1
Ede, RJ1
Mowat, AP1
Williams, R1
Matsukawa, Y1
Saito, N1
Nishinarita, S1
Horie, T1
Ryu, J1
Colombo, B1
Gerloni, V1
Bassetti, D1
Giacchino, R1
Ciravegna, B1
Ferrea, G1
Arima, M1
Takeshita, K1
Yoshino, K1
Kitahara, T1
Suzuki, Y1
Fishel, B1
Tishler, M1
Caspi, D1
Yaron, M1
Vakharlovskiĭ, VG1
Verovaia, AV1
Jeffers, L1
Krzymień, H1
Blattner, RJ1
Dupuy, R1
Vallin, J1
Fabiani, F1
Slovis, TL1
Dubois, RS1
Rodgerson, DO1
Silverman, A1
Holtzman, NA1
Elliott, DA1
Heller, RH1

Reviews

2 reviews available for penicillamine and Jaundice

ArticleYear
[Penicillamine: its use in rheumatoid arthritis].
    Recenti progressi in medicina, 1979, Volume: 66, Issue:2

    Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Eruptions; Drug Evaluation; Female; Fever; Gastrointestinal

1979
[Considerations on the role of copper in rheumatoid arthritis].
    Reumatologia, 1969, Volume: 7, Issue:1

    Topics: Arthritis, Rheumatoid; Copper; Female; Humans; Jaundice; Liver; Male; Penicillamine

1969

Other Studies

13 other studies available for penicillamine and Jaundice

ArticleYear
Prolonged Jaundice in a Patient with Coexisting Hepatitis A Virus Infection and Wilson's Disease.
    Mymensingh medical journal : MMJ, 2021, Volume: 30, Issue:2

    Topics: Adolescent; Bangladesh; Copper; Female; Hepatitis A; Hepatitis A virus; Hepatolenticular Degeneratio

2021
[Pathological changes in lungs and liver after therapy of ulcerative colitis].
    Fortschritte der Medizin, 1980, Apr-03, Volume: 98, Issue:13

    Topics: Amitriptyline; Chlordiazepoxide; Colitis, Ulcerative; Humans; Jaundice; Male; Middle Aged; Penicilla

1980
Wilson's disease in childhood. Variability of clinical presentation.
    Clinical pediatrics, 1983, Volume: 22, Issue:11

    Topics: Adolescent; Aspartate Aminotransferases; Bilirubin; Child; Female; Hemolysis; Hepatolenticular Degen

1983
Therapeutic effect of tiopronin following D-penicillamine toxicity in a patient with rheumatoid arthritis.
    Clinical rheumatology, 1998, Volume: 17, Issue:1

    Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Jaundice; Male; Penicillamine; Retreatme

1998
[Unusual and different clinical aspects of Wilson's disease in 2 sisters].
    Minerva pediatrica, 1979, Oct-31, Volume: 31, Issue:20

    Topics: Acute Kidney Injury; Anemia, Hemolytic; Chelating Agents; Child; Copper; Disseminated Intravascular

1979
Prognosis of Wilson's disease in childhood.
    European journal of pediatrics, 1977, Oct-12, Volume: 126, Issue:3

    Topics: Adolescent; Age Factors; Ascites; Child; Child, Preschool; Hepatolenticular Degeneration; Hepatomega

1977
Fatal aplastic anaemia and liver toxicity caused by D-penicillamine treatment of rheumatoid arthritis.
    Annals of the rheumatic diseases, 1989, Volume: 48, Issue:7

    Topics: Aged; Anemia, Aplastic; Arthritis, Rheumatoid; Female; Humans; Jaundice; Liver; Penicillamine

1989
[Characteristics of visceral manifestations of Wilson-Konovalov disease].
    Sovetskaia meditsina, 1989, Issue:8

    Topics: Adult; Diagnosis, Differential; Female; Hepatitis; Hepatolenticular Degeneration; Humans; Jaundice;

1989
Hemolytic anemia with jaundice and ascites.
    Hospital practice (Office ed.), 1987, May-30, Volume: 22, Issue:5A

    Topics: Adult; Anemia, Hemolytic; Ascites; Copper; Diagnosis, Differential; Female; Hepatolenticular Degener

1987
Hemolytic anemia associated with Wilson's disease.
    The Journal of pediatrics, 1967, Volume: 71, Issue:2

    Topics: Adult; Anemia, Hemolytic; Ascites; Child; Copper; Cornea; Diet Therapy; Dimercaprol; Edetic Acid; Fe

1967
[2 cases of Wilson's disease with hepatic precession in biliary lithiasis].
    Revue internationale d'hepatologie, 1969, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Cholelithiasis; Female; Hepatolenticular Degeneration; Humans; Jaundice; Penicill

1969
The varied manifestations of Wilson's disease.
    The Journal of pediatrics, 1971, Volume: 78, Issue:4

    Topics: Adolescent; Anemia, Hemolytic; Ascites; Ceruloplasmin; Child; Copper; Diseases in Twins; Eye Manifes

1971
Copper intoxication. Report of a case with observations on ceruloplasmin.
    The New England journal of medicine, 1966, Aug-18, Volume: 275, Issue:7

    Topics: Anemia, Hemolytic; Anuria; Aspartate Aminotransferases; Blood; Ceruloplasmin; Child, Preschool; Copp

1966