penicillamine has been researched along with Idiopathic Parkinson Disease in 7 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levodopa was effective, but the wearing-off phenomena were severe." | 1.29 | Effect of D-penicillamine on pharmacokinetics of levodopa in Parkinson's disease. ( Kuno, S; Mizuta, E, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zaleska, B | 1 |
| Peters, L | 1 |
| Steventon, GB | 1 |
| Green, S | 1 |
| Sturman, S | 1 |
| Waring, RH | 1 |
| Williams, AC | 1 |
| Mizuta, E | 1 |
| Kuno, S | 1 |
| Canals, S | 1 |
| Casarejos, MJ | 1 |
| de Bernardo, S | 1 |
| Rodríguez-Martín, E | 1 |
| Mena, MA | 1 |
| Webster, DD | 1 |
| Mortimer, JA | 1 |
| Soyka, D | 1 |
| Tkachev, RA | 1 |
| Markova, ED | 1 |
| Gotovtseva, EV | 1 |
| Barkhatova, VP | 1 |
| Ivanova-Smolenskaia, IA | 1 |
1 review available for penicillamine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
[Progress in the treatment of degenerative diseases of the nervous system. Selected problems].
Topics: Amyotrophic Lateral Sclerosis; Antiparkinson Agents; Humans; Huntington Disease; Lithium; Neostigmin | 1980 |
6 other studies available for penicillamine and Idiopathic Parkinson Disease
| Article | Year |
|---|---|
D-penicillamine metabolism in neurodegenerative diseases: an in vivo/in vitro sulphydryl methylation study.
Topics: Adult; Aged; Aged, 80 and over; Erythrocyte Membrane; Female; Humans; Male; Methylation; Methyltrans | 1994 |
Effect of D-penicillamine on pharmacokinetics of levodopa in Parkinson's disease.
Topics: Absorption; Adult; Dose-Response Relationship, Drug; Drug Interactions; Humans; Levodopa; Male; Park | 1993 |
Glutathione depletion switches nitric oxide neurotrophic effects to cell death in midbrain cultures: implications for Parkinson's disease.
Topics: Alkaloids; Aminoquinolines; Animals; Antioxidants; Apoptosis; Ascorbic Acid; Buthionine Sulfoximine; | 2001 |
Failure of L-dopa to relieve activated rigidity in Parkinson's disease.
Topics: Adult; Amantadine; Extrapyramidal Tracts; Hepatolenticular Degeneration; Humans; Levodopa; Male; Mid | 1977 |
[Syndrome involving the extrapyramidal motor systems and their drug treatment].
Topics: Amantadine; Antiparkinson Agents; Basal Ganglia Diseases; Dihydroxyphenylalanine; gamma-Aminobutyric | 1974 |
[Principles of the pathogenetic therapy of congenital extrapyramidal diseases].
Topics: Adolescent; Adult; Atropine; Basal Ganglia Diseases; Chelating Agents; Chronic Disease; Dihydroxyphe | 1973 |