penicillamine has been researched along with Hypertension, Pulmonary in 15 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Penicillamine (P) and tetramethyl-pyrazine (T) were administered to treat experimentally hypoxic pulmonary hypertension in rats exposed to hypoxia of 380 torr for up to 21-days." | 7.68 | [Effect of penicillamine and tetramethyl pyrazine on the hypoxic pulmonary hypertension in rats]. ( Chen, BH, 1990) |
| "Pulmonary hypertension is one of the major problems in the neonatal period." | 6.38 | [D-penicillamine: old drug, new indication? D-penicillamine reduced pulmonary hypertension induced by free radicals]. ( Lakatos, L; Oroszlán, G; Sanderud, J; Saugstad, OD, 1992) |
| " We report a case of a patient affected by SS, with isolated pulmonary hypertension, who developed bronchiolitis secondary to penicillamine." | 3.73 | Pulmonary involvement in systemic sclerosis due to therapy and as a complication. ( Chiappini, F; Maugeri, L; Zoli, A, 2005) |
| "Penicillamine (P) and tetramethyl-pyrazine (T) were administered to treat experimentally hypoxic pulmonary hypertension in rats exposed to hypoxia of 380 torr for up to 21-days." | 3.68 | [Effect of penicillamine and tetramethyl pyrazine on the hypoxic pulmonary hypertension in rats]. ( Chen, BH, 1990) |
| "Pulmonary hypertension is one of the major problems in the neonatal period." | 2.38 | [D-penicillamine: old drug, new indication? D-penicillamine reduced pulmonary hypertension induced by free radicals]. ( Lakatos, L; Oroszlán, G; Sanderud, J; Saugstad, OD, 1992) |
| "The connective tissue disease systemic sclerosis (SSc) is still a challenge to every rheumatologist." | 1.33 | [Systemic sclerosis--a challenge in rheumatology]. ( Müller-Ladner, U; Saar, P, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 5 (33.33) | 18.2507 |
| 2000's | 7 (46.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chiappini, F | 1 |
| Zoli, A | 1 |
| Maugeri, L | 1 |
| van den Hoogen, FH | 1 |
| Saar, P | 1 |
| Müller-Ladner, U | 1 |
| Mouthon, L | 1 |
| Berezné, A | 1 |
| Poiraudeau, S | 1 |
| Guillevin, L | 1 |
| Lakatos, L | 2 |
| Koh, ET | 1 |
| Lee, P | 1 |
| Gladman, DD | 1 |
| Abu-Shakra, M | 1 |
| Pope, JE | 1 |
| Jacobs, BR | 1 |
| Smith, DJ | 1 |
| Zingarelli, B | 1 |
| Passerini, DJ | 1 |
| Ballard, ET | 1 |
| Brilli, RJ | 1 |
| Resta, TC | 1 |
| Kanagy, NL | 1 |
| Walker, BR | 1 |
| Stummvoll, GH | 1 |
| Oroszlán, G | 1 |
| Sanderud, J | 1 |
| Saugstad, OD | 1 |
| Chen, BH | 1 |
| White, JP | 1 |
| Ward, MJ | 1 |
| Grisanti, M | 1 |
| Vicencio, M | 1 |
| Will, JA | 1 |
| Kay, JM | 1 |
6 reviews available for penicillamine and Hypertension, Pulmonary
| Article | Year |
|---|---|
[Treatment of systemic sclerosis].
Topics: Cyclophosphamide; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Hematopoietic S | 2006 |
[Therapeutic management of systemic sclerosis].
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Anti-Inflam | 2006 |
Treatment of systemic sclerosis.
Topics: Antirheumatic Agents; Calcinosis; Clinical Trials as Topic; Gastrointestinal Diseases; Heart Disease | 1996 |
Current treatment options in systemic Sclerosis (Scleroderma).
Topics: Antirheumatic Agents; Gastrointestinal Diseases; Hematopoietic Stem Cell Transplantation; Humans; Hy | 2002 |
[D-penicillamine: old drug, new indication? D-penicillamine reduced pulmonary hypertension induced by free radicals].
Topics: Animals; Animals, Newborn; Drug Evaluation, Preclinical; Free Radicals; Humans; Hypertension, Pulmon | 1992 |
Drug-induced adverse pulmonary reactions.
Topics: Amiodarone; Asthma; Bleomycin; Carmustine; Drug-Related Side Effects and Adverse Reactions; Gold; Hu | 1985 |
9 other studies available for penicillamine and Hypertension, Pulmonary
| Article | Year |
|---|---|
Pulmonary involvement in systemic sclerosis due to therapy and as a complication.
Topics: Antirheumatic Agents; Bronchiectasis; Bronchiolitis; Female; Follow-Up Studies; Humans; Hypertension | 2005 |
[Systemic sclerosis--a challenge in rheumatology].
Topics: Antibodies, Antinuclear; Gastrointestinal Diseases; Humans; Hypertension, Pulmonary; Immunosuppressi | 2006 |
[Effect of penicillamine D, nitric oxide, or both?].
Topics: Animals; Guinea Pigs; Humans; Hypertension, Pulmonary; Infant, Newborn; Nitric Oxide; Penicillamine | 1993 |
Pulmonary hypertension in systemic sclerosis: an analysis of 17 patients.
Topics: Adult; Anti-Inflammatory Agents; Antirheumatic Agents; Cohort Studies; Demography; Dyspnea; Female; | 1996 |
Soluble nitric oxide donor and surfactant improve oxygenation and pulmonary hypertension in porcine lung injury.
Topics: Amino Acids, Diamino; Animals; Aorta; Disease Models, Animal; Drug Synergism; Hemodynamics; Hyperten | 2000 |
Estradiol-induced attenuation of pulmonary hypertension is not associated with altered eNOS expression.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Chronic Disease; Endoth | 2001 |
[Effect of penicillamine and tetramethyl pyrazine on the hypoxic pulmonary hypertension in rats].
Topics: Animals; Female; Hypertension, Pulmonary; Hypoxia; Male; Penicillamine; Pyrazines; Rats; Rats, Inbre | 1990 |
[Pulmonary involvement in progressive systemic sclerosis].
Topics: Humans; Hypertension, Pulmonary; Lung Diseases; Nifedipine; Penicillamine; Pulmonary Fibrosis; Scler | 1986 |
Hypertensive pulmonary vascular disease associated with papain emphysema in rats.
Topics: Aerosols; Animals; Cardiomegaly; Drug Synergism; Female; Heart; Hypertension, Pulmonary; Hypoxia; Lu | 1974 |