penicillamine has been researched along with Hyperhomocysteinemia in 3 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Hyperhomocysteinemia: Condition in which the plasma levels of homocysteine and related metabolites are elevated (
| Excerpt | Relevance | Reference |
|---|---|---|
| " It has been demonstrated, however, that copper augments the inhibitory effect of homocysteine on nitric oxide (NO)-mediated relaxation of the rat aorta through increased superoxide formation, which reacts with NO thereby reducing the bioavailability of NO." | 1.33 | Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation and superoxide formation in the aorta of the rabbit. ( Angelini, GD; Jeremy, JY; Jones, RA; Koupparis, A; Persad, R; Shukla, N, 2006) |
| " Copper is a catalyst for the generation of H2O2 in the presence of homocysteine and in the presence of copper, H2O2 undergoes reactions resulting in the generation of O2*-, which reacts with NO to produce peroxynitrite (ONOO-), thereby reducing the bioavailability of NO and impairing NO-mediated relaxation of CC." | 1.33 | Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation in the corpus cavernosum in the rabbit. ( Angelini, G; Jeremy, J; Koupparis, AJ; Persad, R; Shukla, N, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bagi, Z | 1 |
| Cseko, C | 1 |
| Tóth, E | 1 |
| Koller, A | 1 |
| Shukla, N | 2 |
| Koupparis, A | 1 |
| Jones, RA | 1 |
| Angelini, GD | 1 |
| Persad, R | 2 |
| Jeremy, JY | 1 |
| Koupparis, AJ | 1 |
| Jeremy, J | 1 |
| Angelini, G | 1 |
3 other studies available for penicillamine and Hyperhomocysteinemia
| Article | Year |
|---|---|
Oxidative stress-induced dysregulation of arteriolar wall shear stress and blood pressure in hyperhomocysteinemia is prevented by chronic vitamin C treatment.
Topics: Animals; Antioxidants; Arterioles; Ascorbic Acid; Blood Pressure; Calcimycin; Dinoprost; F2-Isoprost | 2003 |
Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation and superoxide formation in the aorta of the rabbit.
Topics: Acetophenones; Acetylcholine; Administration, Oral; Animals; Aorta; Blotting, Western; Cyclic GMP; D | 2006 |
Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation in the corpus cavernosum in the rabbit.
Topics: Animals; Chelating Agents; Dietary Supplements; Dose-Response Relationship, Drug; Endothelium, Vascu | 2006 |