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penicillamine and Hyperhomocysteinemia

penicillamine has been researched along with Hyperhomocysteinemia in 3 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Hyperhomocysteinemia: Condition in which the plasma levels of homocysteine and related metabolites are elevated (

Research Excerpts

ExcerptRelevanceReference
" It has been demonstrated, however, that copper augments the inhibitory effect of homocysteine on nitric oxide (NO)-mediated relaxation of the rat aorta through increased superoxide formation, which reacts with NO thereby reducing the bioavailability of NO."1.33Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation and superoxide formation in the aorta of the rabbit. ( Angelini, GD; Jeremy, JY; Jones, RA; Koupparis, A; Persad, R; Shukla, N, 2006)
" Copper is a catalyst for the generation of H2O2 in the presence of homocysteine and in the presence of copper, H2O2 undergoes reactions resulting in the generation of O2*-, which reacts with NO to produce peroxynitrite (ONOO-), thereby reducing the bioavailability of NO and impairing NO-mediated relaxation of CC."1.33Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation in the corpus cavernosum in the rabbit. ( Angelini, G; Jeremy, J; Koupparis, AJ; Persad, R; Shukla, N, 2006)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bagi, Z1
Cseko, C1
Tóth, E1
Koller, A1
Shukla, N2
Koupparis, A1
Jones, RA1
Angelini, GD1
Persad, R2
Jeremy, JY1
Koupparis, AJ1
Jeremy, J1
Angelini, G1

Other Studies

3 other studies available for penicillamine and Hyperhomocysteinemia

ArticleYear
Oxidative stress-induced dysregulation of arteriolar wall shear stress and blood pressure in hyperhomocysteinemia is prevented by chronic vitamin C treatment.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:6

    Topics: Animals; Antioxidants; Arterioles; Ascorbic Acid; Blood Pressure; Calcimycin; Dinoprost; F2-Isoprost

2003
Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation and superoxide formation in the aorta of the rabbit.
    European journal of pharmacology, 2006, Feb-15, Volume: 531, Issue:1-3

    Topics: Acetophenones; Acetylcholine; Administration, Oral; Animals; Aorta; Blotting, Western; Cyclic GMP; D

2006
Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation in the corpus cavernosum in the rabbit.
    BJU international, 2006, Volume: 98, Issue:2

    Topics: Animals; Chelating Agents; Dietary Supplements; Dose-Response Relationship, Drug; Endothelium, Vascu

2006