penicillamine has been researched along with Homocystinuria in 7 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Homocystinuria: Autosomal recessive inborn error of methionine metabolism usually caused by a deficiency of CYSTATHIONINE BETA-SYNTHASE and associated with elevations of homocysteine in plasma and urine. Clinical features include a tall slender habitus, SCOLIOSIS, arachnodactyly, MUSCLE WEAKNESS, genu varus, thin blond hair, malar flush, lens dislocations, an increased incidence of MENTAL RETARDATION, and a tendency to develop fibrosis of arteries, frequently complicated by CEREBROVASCULAR ACCIDENTS and MYOCARDIAL INFARCTION. (From Adams et al., Principles of Neurology, 6th ed, p979)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In an attempt to remove bound homocyst(e)ine, D-penicillamine was given to three patients with pyridoxine-nonresponsive homocystinuria." | 3.66 | The effect of D-penicillamine on protein-bound homocyst(e)ine in homocystinurics. ( Curley, K; Kang, SS; Wong, PW, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kang, SS | 1 |
| Wong, PW | 1 |
| Curley, K | 1 |
| Prockop, DJ | 1 |
| Kivirikko, KI | 1 |
| Tuderman, L | 1 |
| Guzman, NA | 1 |
| Rabenstein, DL | 1 |
| Yamashita, GT | 1 |
| Pestaña, A | 1 |
| Sandoval, IV | 1 |
| Sols, A | 1 |
| Eyre, DR | 1 |
| Schaub, J | 1 |
| Bremer, HJ | 1 |
| Kelly, S | 1 |
| Copeland, W | 1 |
1 review available for penicillamine and Homocystinuria
| Article | Year |
|---|---|
[Diet therapy of inborn errors of metabolism].
Topics: Adult; Carbohydrate Metabolism, Inborn Errors; Child; Cystinosis; Diet Therapy; Dietary Carbohydrate | 1970 |
6 other studies available for penicillamine and Homocystinuria
| Article | Year |
|---|---|
The effect of D-penicillamine on protein-bound homocyst(e)ine in homocystinurics.
Topics: Adolescent; Adult; Blood Proteins; Female; Homocysteine; Homocystine; Homocystinuria; Humans; Male; | 1982 |
The biosynthesis of collagen and its disorders (second of two parts).
Topics: Aging; Animals; Colchicine; Collagen; Collagen Diseases; Ehlers-Danlos Syndrome; Glucosyltransferase | 1979 |
Determination of homocysteine, penicillamine, and their symmetrical and mixed disulfides by liquid chromatography with electrochemical detection.
Topics: Chromatography, High Pressure Liquid; Disulfides; Electrochemistry; Electrodes; Homocysteine; Homocy | 1989 |
Inhibition by homocysteine of serine dehydratase and other pyridoxal 5'-phosphate enzymes of the rat through cofactor blockage.
Topics: Alanine Transaminase; Animals; Cysteine; Homocysteine; Homocystinuria; Humans; L-Serine Dehydratase; | 1971 |
Collagen defects in genetic disorders of connective tissue.
Topics: Aminopropionitrile; Chemical Phenomena; Chemistry; Collagen; Ehlers-Danlos Syndrome; Homocystinuria; | 1974 |
A hypothesis on the homocystinuric's response to pyridoxine.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Chemistry, Clinical; Cysteine; Homocystinuria; Hum | 1968 |