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penicillamine and Hemolysis

penicillamine has been researched along with Hemolysis in 24 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.

Research Excerpts

ExcerptRelevanceReference
"L-1) was enhanced by the presence of epinephrine and to a lesser extent by homocysteine, whereas D-penicillamine, succimer, and mercaptodextran reduced the copper-induced hemolysis."3.70Hemolytic activity of copper sulfate as influenced by epinephrine and chelating thiols. ( Aaseth, J; Afanas'ev, IB; Korkina, LG, 1998)
"Severe hemolysis was reduced to low-grade hemolysis, with no further need for transfusions."1.35A 15-year-old girl with severe hemolytic Wilson's crisis recovered without transplantation after extracorporeal circulation with the Prometheus system. ( Aagaard, NK; Holland-Fischer, P; Jørgensen, SP; Ott, P; Thomsen, KL, 2009)
"Although Wilson's Disease is a treatable disorder, 9 of 15 cases referred with undiagnosed liver disease in the present series died in 3 to 53 days of admission."1.27Wilson's disease in childhood. Variability of clinical presentation. ( Ede, RJ; Mowat, AP; Nazer, H; Williams, R, 1983)
"Symptoms similar to phenomena in immunologic diseases but without specific reactions are classified as pseudo-immunologic."1.27[Pseudo-immunopathy]. ( Baenkler, HW, 1983)
"During childhood, Wilson's disease becomes manifest mostly in the hepatic form."1.26[Morbus Wilson--pathogenesis, diagnosis, therapy, and course (author's transl)]. ( Helwig, H; Werner, JP, 1977)
"This was accompanied by acute renal failure."1.26Fulminant Wilson's disease with haemolysis and renal failure: copper studies and assessment of dialysis regimens. ( Douglas, AP; Gollan, JL; Hamlyn, AN; Sherlock, S, 1977)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199018 (75.00)18.7374
1990's4 (16.67)18.2507
2000's2 (8.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aagaard, NK1
Thomsen, KL1
Holland-Fischer, P1
Jørgensen, SP1
Ott, P1
Faure, A1
Mathon, L1
Poupelin, JC1
Allaouchiche, B1
Chassard, D1
FRICK, PG1
Nazer, H1
Ede, RJ1
Mowat, AP1
Williams, R1
Baenkler, HW1
Vielhauer, W1
Eckardt, V1
Holtermüller, KH1
Lüth, JB1
Schulte, B1
Prellwitz, W1
Sonntag, W1
Shimon, I1
Moses, B1
Sela, BA1
Dolev, E1
Santos Silva, EE1
Sarles, J1
Buts, JP1
Sokal, EM1
Aaseth, J1
Korkina, LG1
Afanas'ev, IB1
Gordon, NC1
Brown, S1
Khosla, VM1
Hansen, LS1
Chugh, KS1
Sakhuja, V1
Werner, JP2
Helwig, H2
Werlin, SL1
Grand, RJ1
Perman, JA1
Watkins, JB1
Hamlyn, AN1
Gollan, JL1
Douglas, AP1
Sherlock, S1
Botha, CJ1
Naude, TW1
Swan, GE1
Guthrie, AJ1
Sim, E1
Dodds, AW1
Goldin, A1
Oroszlán, G1
Lakatos, L1
Balázs, M1
Karmazsin, L1
Aagenaes, O1
Berg, K1
De Sandre, G2
Cortesi, S2
Corrocher, R2
Falezza, G1
Perona, G2
Deiss, A1
Lee, GR1
Cartwright, GE1
Thiel, N1
L'age-Stehr, J1
Wacker, A1
Vettore, L1

Other Studies

24 other studies available for penicillamine and Hemolysis

ArticleYear
A 15-year-old girl with severe hemolytic Wilson's crisis recovered without transplantation after extracorporeal circulation with the Prometheus system.
    Blood purification, 2009, Volume: 28, Issue:2

    Topics: Acetylcysteine; Adolescent; Antidotes; Copper; Extracorporeal Circulation; Female; Free Radical Scav

2009
[Acute cupric sulfate intoxication: pathophysiology and therapy about a case report].
    Annales francaises d'anesthesie et de reanimation, 2003, Volume: 22, Issue:6

    Topics: Adult; Chelating Agents; Copper Sulfate; Erythrocyte Transfusion; Hemolysis; Humans; Intellectual Di

2003
[NOCTURNAL PAROXYSMAL HEMOGLOBINURIA: STUDIES IN VITRO AND IN VIVO ON THE SUSCEPTIBILITY OF HEMOLYSIS TO A MERCAPTANE COMPOUND (PENICILLAMINE)].
    Acta haematologica, 1964, Volume: 32

    Topics: Drug Therapy; Erythrocytes; Hemoglobinuria; Hemoglobinuria, Paroxysmal; Hemolysis; Humans; In Vitro

1964
[PAROXYSMAL NOCTURNAL HEMOGLOBINURIA: IN-VITRO AND IN-VIVO INVESTIGATIONS OF THE INHIBITION OF HEMOLYSIS WITH A MERCAPTAN COMPOUND (PENICILLAMINE)].
    Schweizerische medizinische Wochenschrift, 1964, Sep-26, Volume: 94

    Topics: Cell Death; Circadian Rhythm; Drug Therapy; Hemoglobinuria; Hemoglobinuria, Paroxysmal; Hemolysis; H

1964
Wilson's disease in childhood. Variability of clinical presentation.
    Clinical pediatrics, 1983, Volume: 22, Issue:11

    Topics: Adolescent; Aspartate Aminotransferases; Bilirubin; Child; Female; Hemolysis; Hepatolenticular Degen

1983
[Pseudo-immunopathy].
    Fortschritte der Medizin, 1983, Apr-07, Volume: 101, Issue:13

    Topics: Anaphylaxis; Diagnosis, Differential; Exanthema; Hemolysis; Humans; Immune System Diseases; Penicill

1983
D-penicillamine in Wilson's disease presenting as acute liver failure with hemolysis.
    Digestive diseases and sciences, 1982, Volume: 27, Issue:12

    Topics: Acute Disease; Adolescent; Ceruloplasmin; Copper; Female; Glucocorticoids; Hemolysis; Hepatolenticul

1982
Hemolytic episode in a patient with Wilson's disease treated with zinc.
    Israel journal of medical sciences, 1993, Volume: 29, Issue:10

    Topics: Adult; Anemia, Hemolytic; Copper; Female; Hemolysis; Hepatolenticular Degeneration; Humans; Penicill

1993
Successful medical treatment of severely decompensated Wilson disease.
    The Journal of pediatrics, 1996, Volume: 128, Issue:2

    Topics: Adolescent; Anti-Bacterial Agents; Chelation Therapy; Child; Copper; Female; Hemolysis; Hepatolentic

1996
Hemolytic activity of copper sulfate as influenced by epinephrine and chelating thiols.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1998, Volume: 19, Issue:3

    Topics: Adult; Antidotes; Ceruloplasmin; Chelating Agents; Copper Sulfate; Drug Synergism; Epinephrine; Hemo

1998
Lead poisoning. A comprehensive review and report of a case.
    Oral surgery, oral medicine, and oral pathology, 1979, Volume: 47, Issue:6

    Topics: Adult; Anemia; Child; Diagnosis, Differential; Dimercaprol; Edetic Acid; Gingival Hyperplasia; Hair;

1979
Acute copper intoxication.
    The International journal of artificial organs, 1979, Volume: 2, Issue:4

    Topics: Anemia; Copper; Hemolysis; Humans; Hypoxia; Penicillamine; Sulfates

1979
[Morbus Wilson--pathogenesis, diagnosis, therapy, and course (author's transl)].
    Monatsschrift fur Kinderheilkunde, 1977, Volume: 125, Issue:12

    Topics: Age Factors; Ceruloplasmin; Child; Copper; Hemolysis; Hepatolenticular Degeneration; Humans; Liver C

1977
[Morbus wilson--progressive fatal course of the hepatic form with apoplexy and abscess of the brain (author's transl)].
    Monatsschrift fur Kinderheilkunde, 1977, Volume: 125, Issue:12

    Topics: Adult; Brain Abscess; Cerebrovascular Disorders; Child; Female; Hemolysis; Hepatolenticular Degenera

1977
Diagnostic dilemmas of Wilson's disease: diagnosis and treatment.
    Pediatrics, 1978, Volume: 62, Issue:1

    Topics: Adolescent; Adult; Copper; Diagnosis, Differential; Female; Hemolysis; Hepatolenticular Degeneration

1978
Fulminant Wilson's disease with haemolysis and renal failure: copper studies and assessment of dialysis regimens.
    British medical journal, 1977, Sep-10, Volume: 2, Issue:6088

    Topics: Acute Kidney Injury; Adolescent; Child; Copper; Female; Hemolysis; Hepatolenticular Degeneration; Hu

1977
Evaluation of the efficacy of d-penicillamine and trientine as copper chelators using an in vitro technique involving ovine red blood cells.
    The Onderstepoort journal of veterinary research, 1992, Volume: 59, Issue:3

    Topics: Animals; Copper; Erythrocytes; Female; Hemolysis; In Vitro Techniques; Penicillamine; Sheep; Trienti

1992
Inhibition of the covalent binding reaction of complement component C4 by penicillamine, an anti-rheumatic agent.
    The Biochemical journal, 1989, Apr-15, Volume: 259, Issue:2

    Topics: Anaphylatoxins; Complement C4; Complement C4a; Complement C4b; Complement Pathway, Classical; Cystei

1989
D-penicillamine decreases the H2O2 and phenylhydrazine induced lipid peroxidation in the erythrocyte membrane.
    Acta paediatrica Hungarica, 1986, Volume: 27, Issue:1

    Topics: Animals; Erythrocyte Membrane; Female; Hemolysis; Humans; Hydrogen Peroxide; Lipid Peroxides; Penici

1986
Wilsons disease in childhood. Surviving severe haemolytic crisis with coma.
    Acta pharmacologica et toxicologica, 1986, Volume: 59 Suppl 7

    Topics: Bilirubin; Coma; Copper; Hemolysis; Hepatolenticular Degeneration; Humans; Penicillamine

1986
On the mechanism of the in vitro production of Ham-positive red cells by sulphydryl compounds: role of pH and Free -SH groups.
    British journal of haematology, 1970, Volume: 18, Issue:5

    Topics: beta-Aminoethyl Isothiourea; Blood Group Antigens; Cysteine; Erythrocytes; Glutathione Reductase; He

1970
Hemolytic anemia in Wilson's disease.
    Annals of internal medicine, 1970, Volume: 73, Issue:3

    Topics: Adult; Anemia, Hemolytic; Copper; Erythrocytes; Female; Glucosephosphate Dehydrogenase; Glutathione;

1970
[Studies on the influence of protein synthesis inhibitors on the formation of antibodies].
    Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1967, Volume: 348, Issue:11

    Topics: Animals; Anti-Infective Agents; Antibody Formation; Antimetabolites; Chloroquine; Dactinomycin; Depr

1967
Ham-positive red cells induced in vitro by N-acetylcysteine or D-penicillamine.
    British journal of haematology, 1968, Volume: 15, Issue:5

    Topics: Acetylcholinesterase; Acetylcysteine; beta-Aminoethyl Isothiourea; Cysteine; Erythrocytes; Hemolysis

1968