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penicillamine and Hematuria

penicillamine has been researched along with Hematuria in 16 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Hematuria: Presence of blood in the urine.

Research Excerpts

ExcerptRelevanceReference
"During the period 1976-1983, 67 patients with rheumatoid arthritis attending the arthritis clinics at Groote Schuur Hospital and Princess Alice Orthopaedic Hospital, Cape Town, were treated with penicillamine."7.67Penicillamine therapy in rheumatoid arthritis. ( Grobbelaar, J; Meyers, OL, 1984)
"A patient with advanced rheumatoid arthritis and severe clinical manifestations of rheumatoid vasculitis died of acute renal failure after 30 months of treatment with high-dosage D-penicillamine."7.67Rapidly progressive glomerulonephritis in a patient with rheumatoid arthritis during treatment with high-dosage D-penicillamine. ( Berger, AR; Milstoc, M; Sadjadi, SA; Seelig, MS, 1985)
"This report includes 31 patients who developed a perimembranous glomerulonephritis generally 7 months after the onset of the treatment of various illnesses with D-Penicillamine."7.65[Perimembranous glomerulonephritis after treatment with D-penicillamine. Report on 31 cases (author's transl)]. ( Bohle, A; Gärtner, HV; Hallauer, W; Hoppe-Seyler, G; Lüttgen, FM; Neild, GH; Schollmeyer, P, 1975)
"One hundred sixty-two consecutive patients with rheumatoid arthritis (RA) were studied for possible association between HLA antigens, particularly DR antigens, and disease characteristics and adverse reactions to gold or D-penicillamine treatment."3.67A systematic survey of HLA-A,B,C and D antigens and drug toxicity in rheumatoid arthritis. ( Dequeker, J; Van Wanghe, P; Verdickt, W, 1984)
"During the period 1976-1983, 67 patients with rheumatoid arthritis attending the arthritis clinics at Groote Schuur Hospital and Princess Alice Orthopaedic Hospital, Cape Town, were treated with penicillamine."3.67Penicillamine therapy in rheumatoid arthritis. ( Grobbelaar, J; Meyers, OL, 1984)
"A patient with advanced rheumatoid arthritis and severe clinical manifestations of rheumatoid vasculitis died of acute renal failure after 30 months of treatment with high-dosage D-penicillamine."3.67Rapidly progressive glomerulonephritis in a patient with rheumatoid arthritis during treatment with high-dosage D-penicillamine. ( Berger, AR; Milstoc, M; Sadjadi, SA; Seelig, MS, 1985)
"This report includes 31 patients who developed a perimembranous glomerulonephritis generally 7 months after the onset of the treatment of various illnesses with D-Penicillamine."3.65[Perimembranous glomerulonephritis after treatment with D-penicillamine. Report on 31 cases (author's transl)]. ( Bohle, A; Gärtner, HV; Hallauer, W; Hoppe-Seyler, G; Lüttgen, FM; Neild, GH; Schollmeyer, P, 1975)
"Hypercalciuria was detected in 23% at baseline, 34% in those patients treated for up to 5 years and 37."1.51Urinary abnormalities in children and adolescents with Wilson disease before and during treatment with d-penicillamine. ( Abdel Aziz, H; Abdel Hameed, N; El-Karaksy, H; Fahmy, M; Ghobrial, C; Helmy, H, 2019)
"Hypercalciuria and nephrocalcinosis are not uncommon in patients with Wilson's disease but have only once been reported as the presenting sign."1.29Hypercalciuria and nephrocalcinosis, a feature of Wilson's disease. ( Forster, I; Hoppe, B; Leumann, E; Neuhaus, T; Superti-Furga, A, 1993)
"Gold therapy has been continued in the presence of haematuria without ill effect."1.27Haematuria occurring during antirheumatoid therapy. ( Smith, DH; White, EG; Zaphiropoulos, GC, 1984)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19909 (56.25)18.7374
1990's2 (12.50)18.2507
2000's2 (12.50)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Helmy, H1
Fahmy, M1
Abdel Aziz, H1
Ghobrial, C1
Abdel Hameed, N1
El-Karaksy, H1
Franco, DL1
Keddis, MT1
Zhuang, XH1
Mo, Y1
Jiang, XY1
Chen, SM1
Sinha, R1
Akhtar, S1
Shafagh, H1
Soltani, MA1
Douvoyiannis, M1
Widness, J1
Di Paola, J1
Yadav, N1
Jatzlau, A1
Pohl, J1
Weir, M1
Dequeker, J1
Van Wanghe, P1
Verdickt, W1
White, EG1
Smith, DH1
Zaphiropoulos, GC1
Grobbelaar, J1
Meyers, OL1
Barraclough, D1
Cunningham, TJ1
Muirden, KD1
Hoppe, B1
Neuhaus, T1
Superti-Furga, A1
Forster, I1
Leumann, E1
Gärtner, HV1
Neild, GH1
Bohle, A1
Hallauer, W1
Hoppe-Seyler, G1
Lüttgen, FM1
Schollmeyer, P1
Laufer, J1
Passwell, J1
Lotan, D1
Boichis, H1
Bird, HA1
Leonard, PA1
Bienz, SR1
Clegg, DO1
Ward, JR1
Sadjadi, SA1
Seelig, MS1
Berger, AR1
Milstoc, M1
Burry, HC1

Trials

1 trial available for penicillamine and Hematuria

ArticleYear
Hematuria in patients with rheumatoid arthritis receiving gold and D-penicillamine.
    The Journal of rheumatology, 1987, Volume: 14, Issue:1

    Topics: Adult; Aged; Arthritis, Rheumatoid; Auranofin; Clinical Trials as Topic; Double-Blind Method; Female

1987

Other Studies

15 other studies available for penicillamine and Hematuria

ArticleYear
Urinary abnormalities in children and adolescents with Wilson disease before and during treatment with d-penicillamine.
    Journal of gastroenterology and hepatology, 2019, Volume: 34, Issue:10

    Topics: Adolescent; Age Factors; Albuminuria; Asymptomatic Diseases; Child; Child, Preschool; Egypt; Female;

2019
28-year-old man with Crohn disease and hematuria.
    Mayo Clinic proceedings, 2014, Volume: 89, Issue:12

    Topics: Acute Kidney Injury; Adult; Chelating Agents; Crohn Disease; Hematuria; Humans; Male; Penicillamine;

2014
Analysis of renal impairment in children with Wilson's disease.
    World journal of pediatrics : WJP, 2008, Volume: 4, Issue:2

    Topics: Acetylglucosaminidase; Acidosis, Renal Tubular; Adolescent; Ceruloplasmin; Chelating Agents; Child;

2008
Gross hematuria in a case of Wilson disease: answers.
    Pediatric nephrology (Berlin, Germany), 2012, Volume: 27, Issue:6

    Topics: Acidosis, Renal Tubular; Bicarbonates; Chelating Agents; Child; Hematuria; Hepatolenticular Degenera

2012
Index of suspicion.
    Pediatrics in review, 2005, Volume: 26, Issue:12

    Topics: Chelating Agents; Child; Female; Gastric Outlet Obstruction; Hematuria; Hepatitis; Hepatolenticular

2005
A systematic survey of HLA-A,B,C and D antigens and drug toxicity in rheumatoid arthritis.
    The Journal of rheumatology, 1984, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Cytotoxicity Tests, Immunologic; Dermatitis; Dimerca

1984
Haematuria occurring during antirheumatoid therapy.
    British journal of rheumatology, 1984, Volume: 23, Issue:1

    Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Gold; Hematuria; Humans; Male; Middle Aged; Penicillamin

1984
Penicillamine therapy in rheumatoid arthritis.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1984, May-05, Volume: 65, Issue:18

    Topics: Adult; Aged; Arthritis, Rheumatoid; Hematuria; Humans; Middle Aged; Penicillamine; Proteinuria; Retr

1984
Microscopic haematuria in patients with rheumatoid arthritis on d-penicillamine.
    Australian and New Zealand journal of medicine, 1981, Volume: 11, Issue:6

    Topics: Arthritis, Rheumatoid; False Positive Reactions; Hematuria; Humans; Penicillamine; Urinary Tract Inf

1981
Hypercalciuria and nephrocalcinosis, a feature of Wilson's disease.
    Nephron, 1993, Volume: 65, Issue:3

    Topics: Adolescent; Calcium; Hematuria; Hepatolenticular Degeneration; Humans; Kidney Calculi; Male; Nephroc

1993
[Perimembranous glomerulonephritis after treatment with D-penicillamine. Report on 31 cases (author's transl)].
    Klinische Wochenschrift, 1975, Sep-01, Volume: 53, Issue:17

    Topics: Adolescent; Adult; Aged; Basement Membrane; Female; Glomerulonephritis; Hematuria; Humans; Kidney Gl

1975
Screening for Wilson's disease in the investigation of hematuria.
    Israel journal of medical sciences, 1992, Volume: 28, Issue:6

    Topics: Ceruloplasmin; Child; Child, Preschool; Hematuria; Hepatolenticular Degeneration; Humans; Male; Peni

1992
Should one use second-line agents such as gold and D-penicillamine in a patient with active rheumatoid arthritis and asymptomatic microscopic haematuria for which no cause can be determined?
    British journal of rheumatology, 1989, Volume: 28, Issue:1

    Topics: Arthritis, Rheumatoid; Gold Sodium Thiomalate; Hematuria; Humans; Penicillamine

1989
Rapidly progressive glomerulonephritis in a patient with rheumatoid arthritis during treatment with high-dosage D-penicillamine.
    American journal of nephrology, 1985, Volume: 5, Issue:3

    Topics: Arthritis, Rheumatoid; Female; Glomerulonephritis; Hematuria; Humans; Kidney Glomerulus; Middle Aged

1985
Drug-induced nephropathies.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:9

    Topics: Animals; Arthritis, Rheumatoid; Aspirin; Colic; Complement System Proteins; Glomerular Filtration Ra

1973