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penicillamine and Granulomas

penicillamine has been researched along with Granulomas in 17 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Research Excerpts

ExcerptRelevanceReference
"The influence of D-penicillamine (DPA) on a defined chronic proliferative inflammation in a model granuloma was tested in a long-term experiment."7.65The influence of D-penicillamine on cell proliferation. II. Quantitative investigations during a chronic proliferative inflammation in a model granuloma. ( Bock, G; Paulini, K; Sonntag, W, 1977)
"D-penicillamine was found to have a pro-inflammatory effect when given to rats during the formation of carrageenan air pouch granulomas or simple air cavity linings."3.66The effects of D-penicillamine on non-immune responses to tissue injury. ( Edwards, JC; Sedgwick, AD; Willoughby, DA, 1983)
"Tiopronin (50 mg/kg) and D-penicillamine (50 mg/kg) do not exhibit anti-inflammatory effects in classic animal models (carragenin oedema, granuloma cotton pellets) but suppress pertussis vaccine oedema, an immunological model, when given with a long-lasting dosing regime."3.66Some pharmacological properties of tiopronin. ( Capasso, F, 1981)
"The influence of D-penicillamine (DPA) on a defined chronic proliferative inflammation in a model granuloma was tested in a long-term experiment."3.65The influence of D-penicillamine on cell proliferation. II. Quantitative investigations during a chronic proliferative inflammation in a model granuloma. ( Bock, G; Paulini, K; Sonntag, W, 1977)
"Collagen synthesis, as judged by the accumulation of collagen in a subcutaneous, induced granuloma, was significantly decreased by penicillamine."3.64Collagen defect induced by penicillamine. ( Bavetta, LA; Nimni, ME, 1965)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199016 (94.12)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tovaru, S1
Parlatescu, I1
Dumitriu, AS1
Bucur, A1
Kaplan, I1
Sedgwick, AD1
Edwards, JC1
Willoughby, DA1
Reymond, JL1
Stoebner, P1
Zambelli, P1
Beani, JC1
Amblard, P1
Capasso, F1
Boyle, E1
Mangan, FR1
Otsuka, K2
Murota, S1
Mori, Y3
Paulini, K1
Bock, G1
Sonntag, W1
Nakagawa, H1
Ohkoshi, K1
Tsurufuji, S1
Friedrich, L1
Zimmermann, F1
Beveridge, SJ1
Garrett, IR1
Whitehouse, MW1
Vernon-Roberts, B1
Brooks, PM1
Chiku, S1
Okada, M1
Bazin, S1
Delaunay, A1
Steinetz, B1
Giannina, T1
Butler, M1
Henneman, DH1
Morris, JJ1
Seifter, E1
Rettura, G1
Geever, EF1
Levenson, SM1
Nimni, ME1
Bavetta, LA1

Other Studies

17 other studies available for penicillamine and Granulomas

ArticleYear
Oral complications associated with D-penicillamine treatment for Wilson disease: a clinicopathologic report.
    Journal of periodontology, 2010, Volume: 81, Issue:8

    Topics: Adult; Candidiasis, Oral; Cheilitis; Chelating Agents; Elastic Tissue; Female; Follow-Up Studies; Gi

2010
The effects of D-penicillamine on non-immune responses to tissue injury.
    International journal of tissue reactions, 1983, Volume: 5, Issue:1

    Topics: Animals; Carrageenan; Cell Movement; Dexamethasone; Granuloma; Inflammation; Male; Penicillamine; Ra

1983
Penicillamine induced elastosis perforans serpiginosa: an ultrastructural study of two cases.
    Journal of cutaneous pathology, 1982, Volume: 9, Issue:5

    Topics: Adolescent; Elastic Tissue; Female; Granuloma; Humans; Male; Penicillamine; Skin Diseases

1982
Some pharmacological properties of tiopronin.
    Agents and actions, 1981, Volume: 11, Issue:6-7

    Topics: Amino Acids, Sulfur; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Gossypium; Granuloma; Le

1981
The histology and collagen content of cotton pellet and polyvinyl sponge-induced granulomas in normal and drug-treated rats.
    British journal of experimental pathology, 1980, Volume: 61, Issue:4

    Topics: Aminopropionitrile; Animals; Collagen; Dexamethasone; DNA; Female; Gossypium; Granuloma; Indomethaci

1980
Inhibitory effect of D-penicillamine on the fibrosis caused by bleomycin treatment in rat carrageein granuloma.
    Chemical & pharmaceutical bulletin, 1977, Volume: 25, Issue:6

    Topics: Animals; Bleomycin; Carrageenan; Disease Models, Animal; Granuloma; Male; Penicillamine; Rats

1977
The influence of D-penicillamine on cell proliferation. II. Quantitative investigations during a chronic proliferative inflammation in a model granuloma.
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:12

    Topics: Animals; Body Weight; Cell Division; Collagen; DNA; Granuloma; Inflammation; Male; Penicillamine; Ra

1977
Inhibitory effect of D-penicillamine on degradation of hexosamine-containing substances in the involution of carrageenin granuloma induced by calcium chelate ethylenediaminetetraacetate.
    Chemical & pharmaceutical bulletin, 1976, Volume: 24, Issue:2

    Topics: Animals; Biodegradation, Environmental; Calcium; Carrageenan; Edetic Acid; Granuloma; Hexosamines; M

1976
Effect of D-penicillamine and beta-aminopropionitrile on collagen breakdown of carrageenin granuloma in rats.
    Biochemical pharmacology, 1976, May-15, Volume: 25, Issue:10

    Topics: Aminopropionitrile; Animals; Carrageenan; Collagen; Granuloma; Guanidines; Male; Penicillamine; Rats

1976
[Pharmacology of D-penicillamine].
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:2

    Topics: Administration, Oral; Animals; Biomechanical Phenomena; Burns; Edema; Elasticity; Female; Granulatio

1975
Biodistribution of 64Cu in inflamed rats following administration of two anti-inflammatory copper complexes.
    Agents and actions, 1985, Volume: 17, Issue:1

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Carrageenan; Copper; Edema; Granuloma; I

1985
[Changes in glycosaminoglycans and glycoproteins during development of proliferative inflamed tissue and effect of anti-inflammatory drugs on the metabolism of these hexosamine-containing substances (author's transl)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1974, Volume: 94, Issue:9

    Topics: Animals; Anti-Inflammatory Agents; Betamethasone; Carrageenan; Chondroitin; Glycoproteins; Glycosami

1974
[Action of lathyrogenic substances on the collagen of granulomas].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1972, Jan-24, Volume: 274, Issue:4

    Topics: Animals; Collagen; Female; Granuloma; Mercaptoethylamines; Penicillamine; Polyvinyls; Rats; Skin; Te

1972
The role of sulfhydryl groups in three models of inflammatory disease.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 185, Issue:1

    Topics: Animals; Arthritis; Carrageenan; Croton Oil; Cyclophosphamide; Cysteine; Dexamethasone; Disulfides;

1973
Inhibition of the effect of D-penicillamine on collagen solubility in skin by 17-beta-estradiol cypionate; and the effect of D-penicillamine and 17-beta-estradiol on the abnormalities in rat bone produced by a low calcium diet.
    Endocrinology, 1970, Volume: 87, Issue:3

    Topics: Animals; Aorta; Bone and Bones; Calcium, Dietary; Carbon Isotopes; Carrageenan; Collagen; Deficiency

1970
Effect of penicillamine upon healing wounds.
    The Journal of surgical research, 1969, Volume: 9, Issue:3

    Topics: Alcohols; Animals; Collagen; Collagen Diseases; Diet; Formaldehyde; Granuloma; Hydroxyproline; Male;

1969
Collagen defect induced by penicillamine.
    Science (New York, N.Y.), 1965, Nov-12, Volume: 150, Issue:3698

    Topics: Collagen; Granuloma; Penicillamine; Pyridoxine; Skin; Wound Healing

1965