penicillamine has been researched along with Genetic Predisposition in 7 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hereditary hemochromatosis and Wilson disease are autosomal recessive storage disorders of iron and copper overload, respectively." | 2.50 | Metal storage disorders: Wilson disease and hemochromatosis. ( Kanwar, P; Kowdley, KV, 2014) |
| "Wilson disease is caused by disease-specific mutations of the copper transporting ATPase, ATP7B." | 2.43 | Wilson disease: new insights into pathogenesis, diagnosis, and future therapy. ( Schilsky, ML, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kanwar, P | 1 |
| Kowdley, KV | 1 |
| Fieten, H | 2 |
| Penning, LC | 1 |
| Leegwater, PA | 2 |
| Rothuizen, J | 2 |
| Cocco, GA | 1 |
| Loudianos, G | 1 |
| Pes, GM | 1 |
| Tolu, F | 1 |
| Lepori, MB | 1 |
| Barrocu, M | 1 |
| Sechi, GP | 1 |
| Bruha, R | 1 |
| Marecek, Z | 1 |
| Pospisilova, L | 1 |
| Nevsimalova, S | 1 |
| Vitek, L | 1 |
| Martasek, P | 1 |
| Nevoral, J | 1 |
| Petrtyl, J | 1 |
| Urbanek, P | 1 |
| Jiraskova, A | 1 |
| Ferenci, P | 1 |
| Dirksen, K | 1 |
| van den Ingh, TS | 1 |
| Winter, EA | 1 |
| Watson, AL | 1 |
| Schilsky, ML | 1 |
| Buchanan, WW | 1 |
| Singal, DP | 1 |
2 reviews available for penicillamine and Genetic Predisposition
| Article | Year |
|---|---|
Metal storage disorders: Wilson disease and hemochromatosis.
Topics: Biopsy; Chelating Agents; Disease Progression; Genetic Predisposition to Disease; Genetic Testing; H | 2014 |
Wilson disease: new insights into pathogenesis, diagnosis, and future therapy.
Topics: Adenosine Triphosphatases; Cation Transport Proteins; Cell Transplantation; Copper-Transporting ATPa | 2005 |
5 other studies available for penicillamine and Genetic Predisposition
| Article | Year |
|---|---|
New canine models of copper toxicosis: diagnosis, treatment, and genetics.
Topics: Adaptor Proteins, Signal Transducing; Animals; Chromosome Deletion; Copper; Disease Models, Animal; | 2014 |
"Acquired" hepatocerebral degeneration in a patient heterozygote carrier for a novel mutation in ATP7B gene.
Topics: Adenosine Triphosphatases; Adult; Amino Acid Substitution; Basal Ganglia; Cation Transport Proteins; | 2009 |
Long-term follow-up of Wilson disease: natural history, treatment, mutations analysis and phenotypic correlation.
Topics: Adenosine Triphosphatases; Adolescent; Adult; Asymptomatic Diseases; Cation Transport Proteins; Chel | 2011 |
D-penicillamine treatment of copper-associated hepatitis in Labrador retrievers.
Topics: Animals; Copper; Dog Diseases; Dogs; Female; Genetic Predisposition to Disease; Liver Cirrhosis; Mal | 2013 |
Is there a need to reclassify adult rheumatoid arthritis?
Topics: Arthritis, Rheumatoid; Female; Genes; Genetic Predisposition to Disease; Gold; HLA-DQ Antigens; HLA- | 1990 |