penicillamine has been researched along with Focal Neurologic Deficits in 24 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diffuse fasciculations developed in a patient with rheumatoid arthritis who had received D-penicillamine for 6 months." | 7.66 | Diffuse fasciculations induced by D-penicillamine. ( Pinals, RS, 1983) |
| "Diffuse fasciculations developed in a patient with rheumatoid arthritis who had received D-penicillamine for 6 months." | 3.66 | Diffuse fasciculations induced by D-penicillamine. ( Pinals, RS, 1983) |
| "These data suggest that neurological manifestations occur frequently in those abusing leaded gasoline and that chelation therapy has an important place in their management." | 1.26 | The neurological manifestations of chronic inhalation of leaded gasoline. ( Boeckx, RL; Chow, PN; Rjani, KR; Seshia, SS, 1978) |
| "Thus, since Wilson's disease may present with chronic active hepatitis or cirrhosis with a normal ESR and without ocular or neurologic signs, it may be a more common cause of liver disease in young people than has been appreciated." | 1.26 | Wilson's disease: a common liver disorder? ( Barr, R; Hyslop, PS; Sass-Kortsak, A; Thompson, WG, 1977) |
| "A patient with Wilson's disease presented at the age of 41 with a neurological defect and gross osteomalacia secondary to a defect of renal tubular reabsorption." | 1.25 | Effect of treatment on renal function in severe osteomalacia due to Wilson's disease. ( Monro, P, 1970) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HERRING, VG | 1 |
| KLATSKIN, G | 1 |
| BRANDT, IK | 1 |
| BOUDIN, G | 1 |
| PEPIN, B | 1 |
| LAURAS, A | 1 |
| BARRAINE, R | 1 |
| STERNLIEB, I | 1 |
| SCHEINBERG, IH | 1 |
| JAFFE, IA | 1 |
| Wallauer, P | 1 |
| Harbauer, H | 1 |
| Pinals, RS | 1 |
| Seshia, SS | 1 |
| Rjani, KR | 1 |
| Boeckx, RL | 1 |
| Chow, PN | 1 |
| Thompson, WG | 1 |
| Hyslop, PS | 1 |
| Barr, R | 1 |
| Sass-Kortsak, A | 1 |
| Strickland, GT | 1 |
| Leu, ML | 1 |
| Walshe, JM | 1 |
| Ott, VR | 1 |
| Schmidt, KL | 1 |
| Gharib, M | 1 |
| Rustam, H | 1 |
| Hamdi, T | 1 |
| Bloch, KJ | 1 |
| Maki, DG | 1 |
| Karma, A | 1 |
| Kark, RA | 1 |
| Poskanzer, DC | 1 |
| Bullock, JD | 1 |
| Boylen, G | 1 |
| Monro, P | 1 |
| Hartl, J | 2 |
| Hauftová, D | 2 |
| Seidlová, V | 1 |
| Růzicková, R | 1 |
| Kubĕna, K | 1 |
| Slavícek, J | 1 |
| Slovis, TL | 1 |
| Dubois, RS | 1 |
| Rodgerson, DO | 1 |
| Silverman, A | 1 |
| Wewalka, F | 1 |
| Schnack, H | 1 |
| Barraquer-Bordas, L | 1 |
| Tolosa, E | 1 |
| Grau-Veciana, JM | 1 |
| Salisachs-Rowe, P | 1 |
| Tavolato, B | 1 |
| De Zanche, L | 1 |
2 reviews available for penicillamine and Focal Neurologic Deficits
| Article | Year |
|---|---|
[Treatment of rheumatoid arthritis using D-penicillamine].
Topics: Adult; Agranulocytosis; Arthritis, Rheumatoid; Biodegradation, Environmental; Female; Humans; Kidney | 1974 |
Hyperviscosity syndromes associated with immunoglobulin abnormalities.
Topics: Animals; Arthritis, Rheumatoid; Blood Protein Disorders; Blood Viscosity; Cardiovascular Diseases; E | 1973 |
22 other studies available for penicillamine and Focal Neurologic Deficits
| Article | Year |
|---|---|
HEPATOLENTICULAR DEGENERATION: OBSERVATIONS ON A CASE TREATED WITH D-PENICILLAMINE.
Topics: Blood Chemical Analysis; Ceruloplasmin; Child; Copper; Electrolytes; Hepatolenticular Degeneration; | 1963 |
[OUR EXPERIENCE IN THE TREATMENT OF WILSON'S DISEASE WITH PENICILLAMINE].
Topics: Adolescent; Copper; Dimercaprol; Edetic Acid; Hepatolenticular Degeneration; Humans; Neurologic Mani | 1963 |
PENICILLAMINE THERAPY FOR HEPATOLENTICULAR DEGENERATION.
Topics: Amenorrhea; Avitaminosis; Bone and Bones; Copper; Desensitization, Immunologic; Diet; Drug Eruptions | 1964 |
RHEUMATOID ARTHRITIS WITH ARTERITIS; REPORT OF A CASE TREATED WITH PENICILLAMINE.
Topics: Amputation, Surgical; Arteritis; Arthritis; Arthritis, Rheumatoid; Drug Therapy; Foot Diseases; Gang | 1964 |
[On the course and therapy of a juvenile Wilson's disease case].
Topics: Adolescent; Diet Therapy; Female; Hepatolenticular Degeneration; Humans; Neurologic Manifestations; | 1967 |
Diffuse fasciculations induced by D-penicillamine.
Topics: Arthritis, Rheumatoid; Fasciculation; Female; Humans; Middle Aged; Neurologic Manifestations; Penici | 1983 |
The neurological manifestations of chronic inhalation of leaded gasoline.
Topics: Adolescent; Adult; Child; Child, Preschool; Dimercaprol; Edetic Acid; Electrocardiography; Electroen | 1978 |
Wilson's disease: a common liver disorder?
Topics: Adolescent; Adult; Aspartate Aminotransferases; Blood Sedimentation; Ceruloplasmin; Child; Copper; E | 1977 |
Wilson's disease. Clinical and laboratory maniestations in 40 patients.
Topics: Adolescent; Adult; Blood Cell Count; Blood Platelets; Ceruloplasmin; Child; Copper; Cornea; Female; | 1975 |
Management of penicillamine nephropathy in Wilson's disease: a new chelating agent.
Topics: Adolescent; Chelating Agents; Chlorides; Copper; Ethylenediamines; Hepatolenticular Degeneration; Hu | 1969 |
Unusual problems tend to appear in crops.
Topics: Adult; Biopsy; Ceruloplasmin; Child; Diagnosis, Differential; Diet; Dimercaprol; Eye Manifestations; | 1971 |
Methyl mercury poisoning in Iraq. A neurological study.
Topics: Adolescent; Adult; Ataxia; Cerebellar Diseases; Child; Child, Preschool; Decerebrate State; Disease | 1974 |
Ophthalmologic and genetic aspects of Wilson's disease (hepatolenticular degeneration).
Topics: Adult; Biopsy; Ceruloplasmin; Copper; Eye Manifestations; Female; Finland; Hepatolenticular Degenera | 1973 |
Mercury poisoning and its treatment with N-acetyl-D,L-penicillamine.
Topics: Adult; Chronic Disease; Copper; Environmental Exposure; Feces; Humans; Male; Mercury; Mercury Poison | 1971 |
Effect of treatment on renal function in severe osteomalacia due to Wilson's disease.
Topics: Adult; Alkaline Phosphatase; Amino Acids; Ergocalciferols; Fanconi Syndrome; Hepatolenticular Degene | 1970 |
[Therapy of neurologic manifestations of Wilson's disease using penicillamine].
Topics: Adolescent; Adult; Female; Hepatolenticular Degeneration; Humans; Male; Neurologic Manifestations; P | 1970 |
[Penicillamine in the treatment of Wilson's disease. Clinical picture].
Topics: Adolescent; Adult; Child; Female; Handwriting; Hepatolenticular Degeneration; Humans; Male; Neurolog | 1970 |
The varied manifestations of Wilson's disease.
Topics: Adolescent; Anemia, Hemolytic; Ascites; Ceruloplasmin; Child; Copper; Diseases in Twins; Eye Manifes | 1971 |
[Wilson's disease. Introduction to current problems (early diagnosis and therapy)].
Topics: Adolescent; Adult; Agranulocytosis; Ceruloplasmin; Child; Copper; Female; Hepatolenticular Degenerat | 1967 |
[Urine copper determination in Wilson's disease during therapy].
Topics: Adult; Blood Cell Count; Child; Copper; Hepatolenticular Degeneration; Humans; Male; Neurologic Mani | 1967 |
[Clinical, bioptic, biochemical and therapeutic study of a case of hepatolenticular degeneration of K. Wilson with pseudotumoral onset].
Topics: Biopsy; Blood Protein Electrophoresis; Cerebral Angiography; Ceruloplasmin; Child; Eye Manifestation | 1966 |
[Therapeutic considerations on Wilson's disease].
Topics: Adult; Dimercaprol; Hepatolenticular Degeneration; Humans; Male; Mental Disorders; Movement Disorder | 1966 |