Page last updated: 2024-11-07

penicillamine and Fasciitis

penicillamine has been researched along with Fasciitis in 7 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Fasciitis: Inflammation of the fascia. There are three major types: 1, Eosinophilic fasciitis, an inflammatory reaction with eosinophilia, producing hard thickened skin with an orange-peel configuration suggestive of scleroderma and considered by some a variant of scleroderma; 2, Necrotizing fasciitis (FASCIITIS, NECROTIZING), a serious fulminating infection (usually by a beta hemolytic streptococcus) causing extensive necrosis of superficial fascia; 3, Nodular/Pseudosarcomatous /Proliferative fasciitis, characterized by a rapid growth of fibroblasts with mononuclear inflammatory cells and proliferating capillaries in soft tissue, often the forearm; it is not malignant but is sometimes mistaken for fibrosarcoma.

Research Excerpts

ExcerptRelevanceReference
" CS plus d-penicillamine (d-Pen) in severe eosinophilic fasciitis."9.22Severe eosinophilic fasciitis: comparison of treatment with D-penicillamine plus corticosteroids vs. corticosteroids alone. ( Bai, R; Jimenez, SA; Kebede, AG; Mendoza, FA, 2016)
"Eosinophilic fasciitis (EF) is a rare disease characterized by symmetrical thickness and hardening of the skin, especially localized to forearms and thorax, with eosinophilia."6.48D-penicillamine in the treatment of eosinophilic fasciitis: case reports and review of the literature. ( Cesinaro, AM; Colaci, M; Ferri, C; Giuggioli, D; Manfredi, A; Manzini, CU; Sebastiani, M, 2012)
" CS plus d-penicillamine (d-Pen) in severe eosinophilic fasciitis."5.22Severe eosinophilic fasciitis: comparison of treatment with D-penicillamine plus corticosteroids vs. corticosteroids alone. ( Bai, R; Jimenez, SA; Kebede, AG; Mendoza, FA, 2016)
"Eosinophilic fasciitis (EF) is a rare disease characterized by symmetrical thickness and hardening of the skin, especially localized to forearms and thorax, with eosinophilia."2.48D-penicillamine in the treatment of eosinophilic fasciitis: case reports and review of the literature. ( Cesinaro, AM; Colaci, M; Ferri, C; Giuggioli, D; Manfredi, A; Manzini, CU; Sebastiani, M, 2012)
"All children who were referred for fasciitis were included in the study."1.28The fasciitis-morphea complex in children. ( Miller, JJ, 1992)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19902 (28.57)18.7374
1990's3 (42.86)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mendoza, FA1
Bai, R1
Kebede, AG1
Jimenez, SA1
Manzini, CU1
Sebastiani, M1
Giuggioli, D1
Manfredi, A1
Colaci, M1
Cesinaro, AM1
Ferri, C1
Caspi, D1
Fishel, R1
Varon, M1
Yona, E1
Baratz, M1
Yaron, M1
Farrington, ML1
Haas, JE1
Nazar-Stewart, V1
Mellins, ED1
Kato, Y1
Naito, Y1
Narita, Y1
Kuzuhara, S1
Miller, JJ1
Shaposhnikov, OK1
Rodionov, AN1
Samtsov, AV1

Reviews

1 review available for penicillamine and Fasciitis

ArticleYear
D-penicillamine in the treatment of eosinophilic fasciitis: case reports and review of the literature.
    Clinical rheumatology, 2012, Volume: 31, Issue:1

    Topics: Antirheumatic Agents; Drug Resistance; Drug Substitution; Eosinophilia; Fasciitis; Female; Glucocort

2012

Trials

1 trial available for penicillamine and Fasciitis

ArticleYear
Severe eosinophilic fasciitis: comparison of treatment with D-penicillamine plus corticosteroids vs. corticosteroids alone.
    Scandinavian journal of rheumatology, 2016, Volume: 45, Issue:2

    Topics: Adult; Aged; Antirheumatic Agents; Drug Therapy, Combination; Eosinophilia; Fasciitis; Female; Gluco

2016

Other Studies

5 other studies available for penicillamine and Fasciitis

ArticleYear
Multisystem presentation of eosinophilic fasciitis.
    Rheumatology and rehabilitation, 1982, Volume: 21, Issue:4

    Topics: Adult; Ankle Joint; Azathioprine; Blood Sedimentation; Bone Marrow Examination; Elbow Joint; Eosinop

1982
Eosinophilic fasciitis in children frequently progresses to scleroderma-like cutaneous fibrosis.
    The Journal of rheumatology, 1993, Volume: 20, Issue:1

    Topics: Adolescent; Biopsy; Child; Child, Preschool; Eosinophilia; Fasciitis; Female; Fibrosis; Humans; Male

1993
D-penicillamine-induced myasthenia gravis in a case of eosinophilic fasciitis.
    Journal of the neurological sciences, 1997, Feb-27, Volume: 146, Issue:1

    Topics: Eosinophilia; Fasciitis; Female; Humans; Middle Aged; Myasthenia Gravis; Penicillamine; Scleroderma,

1997
The fasciitis-morphea complex in children.
    American journal of diseases of children (1960), 1992, Volume: 146, Issue:6

    Topics: Adolescent; Antibodies, Antinuclear; Biopsy; Blood Sedimentation; Child; Child, Preschool; Eosinophi

1992
[Schulman's eosinophilic fasciitis: update on diagnosis and treatment].
    Vestnik dermatologii i venerologii, 1986, Issue:5

    Topics: Eosinophilia; Fasciitis; Female; Humans; Middle Aged; Penicillamine; Syndrome

1986