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penicillamine and Experimental Radiation Injuries

penicillamine has been researched along with Experimental Radiation Injuries in 15 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Research Excerpts

ExcerptRelevanceReference
" Long-term administration of D-penicillamine at a rate of 100 mg/kg/day had no significant effect on the LD50/160 in mice following pulmonary irradiation."1.26The effect of penicillamine on radiation-induced pulmonary lethality in mice. ( Fischer, JJ; Percarpio, B, 1979)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199014 (93.33)18.7374
1990's1 (6.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BACQ, ZM1
ALEXANDER, P1
Okuyama, S2
Mishina, H2
Matsuzawa, T1
Ward, WF7
Shih-Hoellwarth, A4
Tuttle, RD1
Pearlman, HG1
Kepka, AG1
Port, CD2
Takahashi, K1
Johnson, PM1
Kim, YT1
Percarpio, B1
Fischer, JJ1
Fisher, DR1
Dunavant, BG1
Peterson, LM1
Evans, ML1
Graham, MM1
Eary, JF1
Dahlen, DD1
Molteni, A1
Fitzsimons, EJ1
Hinz, J1
Langendorff, H1
Field, L1
Sweetman, BJ1
Bellas, M1

Reviews

1 review available for penicillamine and Experimental Radiation Injuries

ArticleYear
[Recent results of research on the effect of chemical substances during irradiation of higher organisms].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:4

    Topics: Animals; Antimetabolites; Cricetinae; Dogs; Endotoxins; Guinea Pigs; Haplorhini; Homocysteine; Human

1970

Other Studies

14 other studies available for penicillamine and Experimental Radiation Injuries

ArticleYear
IMPORTANCE FOR RADIO-PROTECTION OF THE REACTION OF CELL TO SULPHYDRYL AND DISULPHIDE COMPOUNDS.
    Nature, 1964, Jul-11, Volume: 203

    Topics: Cystamine; Cysteamine; Disulfides; Glutathione; Guanidines; Injections, Intraperitoneal; Mercaptoeth

1964
Principia of cancer therapy VIII. Role of D-penicillamine in the prevention of radiation pneumonitis and fibrosis: an experimental demonstration.
    The science reports of the research institutes, Tohoku University. Ser. C, Medicine. Tohoku Daigaku, 1984, Volume: 31, Issue:1-4

    Topics: Animals; Female; Lung; Penicillamine; Pneumonia; Pulmonary Fibrosis; Radiation Injuries, Experimenta

1984
Collagen accumulation in irradiated rat lung: modification by D-penicillamine.
    Radiology, 1983, Volume: 146, Issue:2

    Topics: Animals; Cobalt Radioisotopes; Collagen; Gamma Rays; Hydroxyproline; Lung; Male; Penicillamine; Pulm

1983
Whole-thorax radiation lethality in penicillamine-treated mice.
    Radiation research, 1982, Volume: 90, Issue:2

    Topics: Animals; Body Weight; Cobalt Radioisotopes; Dose-Response Relationship, Radiation; Gamma Rays; Male;

1982
The ultrastructure of radiation injury in rat lung: modification by D-penicillamine.
    Radiation research, 1982, Volume: 92, Issue:1

    Topics: Animals; Endothelium; Epithelium; Lung; Male; Penicillamine; Pulmonary Alveoli; Pulmonary Fibrosis;

1982
Radiation-induced pulmonary arterial perfusion defects: modification by D-penicillamine.
    Radiology, 1981, Volume: 139, Issue:1

    Topics: Animals; Lung; Male; Penicillamine; Pulmonary Circulation; Radiation Injuries, Experimental; Radionu

1981
Increased radiation morbidities, hypocupremia and hyperlipoperoxidemia in the rat induced by D-penicillamine administration.
    Gan, 1980, Volume: 71, Issue:5

    Topics: Animals; Copper; Female; Lipid Peroxides; Male; Penicillamine; Radiation Injuries, Experimental; Rat

1980
Survival of penicillamine-treated mice following whole-body irradiation.
    Radiation research, 1980, Volume: 81, Issue:1

    Topics: Animals; Gamma Rays; Male; Mice; Penicillamine; Pulmonary Fibrosis; Radiation Dosage; Radiation Inju

1980
Modification of radiation-induced pulmonary fibrosis in rats.
    Radiology, 1979, Volume: 131, Issue:3

    Topics: Animals; Body Weight; Diet; Gamma Rays; Lung; Male; Microscopy, Electron; Penicillamine; Pulmonary F

1979
The effect of penicillamine on radiation-induced pulmonary lethality in mice.
    Radiology, 1979, Volume: 131, Issue:3

    Topics: Animals; Diet; Lung; Mice; Penicillamine; Pulmonary Fibrosis; Radiation Injuries, Experimental; Radi

1979
Internal decontamination of radiocobalt.
    Health physics, 1978, Volume: 35, Issue:2

    Topics: Animals; Calcium; Cobalt; Cobalt Radioisotopes; Drug Therapy, Combination; Male; Mice; Mice, Inbred

1978
Vascular response to radiation injury in the rat lung.
    Radiation research, 1992, Volume: 129, Issue:2

    Topics: Animals; Captopril; Cesium Radioisotopes; Cyproheptadine; Dexamethasone; Diethylcarbamazine; Gamma R

1992
Serum copper concentration as an index of lung injury in rats exposed to hemithorax irradiation.
    Radiation research, 1988, Volume: 114, Issue:3

    Topics: Animals; Cobalt Radioisotopes; Copper; Epoprostenol; Gamma Rays; Lung; Male; Penicillamine; Radiatio

1988
Biologically oriented organic sulfur chemistry. II. Formation of hemimercaptals or hemimercaptoles as a means of latentiating thiols.
    Journal of medicinal chemistry, 1969, Volume: 12, Issue:4

    Topics: Animals; Arthritis, Rheumatoid; Cobalt Isotopes; Mice; Penicillamine; Radiation Injuries, Experiment

1969