penicillamine has been researched along with Experimental Hepatoma in 11 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The formation of liver metastases involves interactions between intravascular cancer cells and the hepatic microvasculature." | 1.31 | B16 melanoma cell arrest in the mouse liver induces nitric oxide release and sinusoidal cytotoxicity: a natural hepatic defense against metastasis. ( Ahmed, N; Hasinoff, BB; McIntosh, AR; Nance, DM; Orr, FW; Rector, ES; Wang, HH, 2000) |
| "Trientine treatment resulted in a marked suppression of neovascularization and increase of apoptosis in the tumor, whereas tumor cell proliferation itself was not altered." | 1.31 | The copper-chelating agent, trientine, suppresses tumor development and angiogenesis in the murine hepatocellular carcinoma cells. ( De Lorenzo, MS; Fukui, H; Gomez, DE; Ikenaka, Y; Kishida, H; Kuriyama, S; Nakae, D; Nakatani, T; Noguchi, R; Okuda, H; Tejera, AM; Tsujinoue, H; Yoshii, J; Yoshiji, H, 2001) |
| "adjuvant arthritis, were found to increase tumour cell 3H-TdR incorporation, compared to macrophages from nonarthritic rats." | 1.26 | Antirheumatic drugs and macrophage function: effects on tumour cell growth in vitro. ( Arrigoni-Martelli, E; Binderup, L; Bramm, E, 1982) |
| "The growth of 9A and 7316A Morris hepatomas was studied in pyridoxine (PN)-depleted and in pair-fed control Buffalo rats." | 1.26 | Control of tumor growth by pyridoxine restriction or treatment with an antivitamin agent. ( Tryfiates, GP, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (45.45) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Binderup, L | 1 |
| Bramm, E | 1 |
| Arrigoni-Martelli, E | 1 |
| Tryfiates, GP | 2 |
| Morris, HP | 1 |
| Sonidis, GP | 1 |
| Fujii, Y | 1 |
| Shimizu, K | 1 |
| Satoh, M | 1 |
| Fujita, M | 1 |
| Fujioka, Y | 1 |
| Li, Y | 2 |
| Togashi, Y | 1 |
| Takeichi, N | 1 |
| Nagashima, K | 1 |
| Phillips, JD | 1 |
| Kinikini, DV | 1 |
| Yu, Y | 1 |
| Guo, B | 1 |
| Leibold, EA | 1 |
| Joshi, MS | 1 |
| Ponthier, JL | 1 |
| Lancaster, JR | 1 |
| Wang, HH | 1 |
| McIntosh, AR | 1 |
| Hasinoff, BB | 1 |
| Rector, ES | 1 |
| Ahmed, N | 1 |
| Nance, DM | 1 |
| Orr, FW | 1 |
| Yoshii, J | 1 |
| Yoshiji, H | 1 |
| Kuriyama, S | 1 |
| Ikenaka, Y | 1 |
| Noguchi, R | 1 |
| Okuda, H | 1 |
| Tsujinoue, H | 1 |
| Nakatani, T | 1 |
| Kishida, H | 1 |
| Nakae, D | 1 |
| Gomez, DE | 1 |
| De Lorenzo, MS | 1 |
| Tejera, AM | 1 |
| Fukui, H | 1 |
| Huber, M | 1 |
| Keppler, D | 1 |
| Bertram, B | 1 |
| Frei, E | 1 |
| Scherf, HR | 1 |
| Schuhmacher, J | 1 |
| Tacchi, AM | 1 |
| Wiessler, M | 1 |
1 review available for penicillamine and Experimental Hepatoma
| Article | Year |
|---|---|
Vitamin B6 and cancer (review).
Topics: Animals; Biotransformation; Cell Division; Fluorodeoxyuridylate; Fluorouracil; Liver Neoplasms, Expe | 1981 |
10 other studies available for penicillamine and Experimental Hepatoma
| Article | Year |
|---|---|
Antirheumatic drugs and macrophage function: effects on tumour cell growth in vitro.
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Chloroquine; Female; Levamiso | 1982 |
Control of tumor growth by pyridoxine restriction or treatment with an antivitamin agent.
Topics: Animals; Female; Liver Neoplasms, Experimental; Neoplasms, Experimental; Penicillamine; Pyridoxine; | 1981 |
Histochemical demonstration of copper in LEC rat liver.
Topics: Animals; Copper; Histocytochemistry; Liver; Liver Neoplasms, Experimental; Male; Paraffin Embedding; | 1993 |
Differential regulation of IRP1 and IRP2 by nitric oxide in rat hepatoma cells.
Topics: Animals; Cytokines; Gene Expression Regulation, Neoplastic; Iron Regulatory Protein 1; Iron Regulato | 1996 |
Cellular antioxidant and pro-oxidant actions of nitric oxide.
Topics: Animals; Antioxidants; Azetidines; Cells, Cultured; Free Radical Scavengers; Glutathione; Hydrogen P | 1999 |
B16 melanoma cell arrest in the mouse liver induces nitric oxide release and sinusoidal cytotoxicity: a natural hepatic defense against metastasis.
Topics: Animals; Apoptosis; Endothelium, Vascular; Female; Liver; Liver Neoplasms, Experimental; Melanoma, E | 2000 |
The copper-chelating agent, trientine, suppresses tumor development and angiogenesis in the murine hepatocellular carcinoma cells.
Topics: Animals; Apoptosis; Cell Division; Chelating Agents; Copper; Female; Liver Neoplasms, Experimental; | 2001 |
[Abnormal hepatic copper accumulation and its significance in LEC rats developing spontaneous hepatitis and hepatoma].
Topics: Alanine Transaminase; Animals; Ceruloplasmin; Copper; Disease Models, Animal; Female; Hepatitis, Ani | 1991 |
Inhibition of leukotriene D4 catabolism by D-penicillamine.
Topics: Animals; Bile; Dipeptidases; Kinetics; Liver Neoplasms, Experimental; Penicillamine; Platelet Activa | 1987 |
Influence of a prolonged treatment with disulfiram and D(-)penicillamine on nitrosodiethylamine-induced biological and biochemical effects in rats. I. Investigations on the drug metabolizing system.
Topics: Animals; Diethylnitrosamine; Disulfiram; Drug Interactions; Enzyme Inhibitors; Esophageal Neoplasms; | 1985 |