penicillamine has been researched along with Embryopathies in 7 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mother we present is a Wilson's disease patient who had been compliant with D-penicillamine for the preceding 13 years." | 5.32 | Transient fetal myelosuppressive effect of D-penicillamine when used in pregnancy. ( Akisu, M; Aydogdu, S; Kultursay, N; Ozgenc, F; Yagci, RV; Yalaz, M, 2003) |
| " D-Penicillamine may be teratogenic thus it should not be commenced during pregnancy and if a patient becomes pregnant whilst receiving the drug, it should be slowly withdrawn or the dosage reduced." | 4.77 | Antirheumatic medication in pregnancy. ( Brooks, PM; Needs, CJ, 1985) |
| "We report a chromosomally normal infant boy with congenital diffuse cutis laxa, severe micrognathia, contractures of all limbs, and central nervous system abnormalities including agenesis of the corpus callosum, born to a woman taking D-penicillamine (DP) for Wilson disease (WD) throughout her pregnancy." | 3.72 | Infant with severe penicillamine embryopathy born to a woman with Wilson disease. ( Hogge, WA; McPherson, E; Pinter, R, 2004) |
| " During treatment with the basic drugs: gold, D-penicillamine and chloroquine, pregnancy should be avoided." | 3.65 | [Problems of rheumatic therapy in pregnancy (author's transl)]. ( Bischof, P, 1976) |
| "The mother we present is a Wilson's disease patient who had been compliant with D-penicillamine for the preceding 13 years." | 1.32 | Transient fetal myelosuppressive effect of D-penicillamine when used in pregnancy. ( Akisu, M; Aydogdu, S; Kultursay, N; Ozgenc, F; Yagci, RV; Yalaz, M, 2003) |
| "A patient with untreated Wilson's disease showed the possibility of fetal liver damage and copper accumulation in the placenta by this disease." | 1.29 | Copper disposition of the fetus and placenta in a patient with untreated Wilson's disease. ( Anai, T; Inoue, I; Matsui, N; Miyakawa, I; Oga, M; Yoshimatsu, J, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yalaz, M | 1 |
| Aydogdu, S | 1 |
| Ozgenc, F | 1 |
| Akisu, M | 1 |
| Kultursay, N | 1 |
| Yagci, RV | 1 |
| Pinter, R | 1 |
| Hogge, WA | 1 |
| McPherson, E | 1 |
| Oga, M | 1 |
| Matsui, N | 1 |
| Anai, T | 1 |
| Yoshimatsu, J | 1 |
| Inoue, I | 1 |
| Miyakawa, I | 1 |
| Bischof, P | 1 |
| Needs, CJ | 1 |
| Brooks, PM | 1 |
| Haley, TJ | 1 |
| Snyder, RD | 1 |
2 reviews available for penicillamine and Embryopathies
| Article | Year |
|---|---|
Antirheumatic medication in pregnancy.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Antineoplas | 1985 |
Saturnism, pediatric and adult lead poisoning.
Topics: Adult; Central Nervous System Diseases; Chicago; Child; Child, Preschool; Edetic Acid; Environmental | 1971 |
5 other studies available for penicillamine and Embryopathies
| Article | Year |
|---|---|
Transient fetal myelosuppressive effect of D-penicillamine when used in pregnancy.
Topics: Chelating Agents; Female; Fetal Diseases; Hepatolenticular Degeneration; Humans; Infant, Newborn; Le | 2003 |
Infant with severe penicillamine embryopathy born to a woman with Wilson disease.
Topics: Abnormalities, Drug-Induced; Agenesis of Corpus Callosum; Cutis Laxa; Female; Fetal Diseases; Fetus; | 2004 |
Copper disposition of the fetus and placenta in a patient with untreated Wilson's disease.
Topics: Adult; Ceruloplasmin; Copper; Female; Fetal Diseases; Fetus; Hepatolenticular Degeneration; Humans; | 1993 |
[Problems of rheumatic therapy in pregnancy (author's transl)].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Azathioprine; Chloroquine; Female; Fetal Diseases | 1976 |
The involuntary movements of chronic mercury poisoning.
Topics: Adolescent; Adult; Ataxia; Child; Dimercaprol; Female; Fetal Diseases; Humans; Infant, Newborn; Infa | 1972 |