penicillamine has been researched along with Ehlers-Danlos Syndrome in 8 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Ehlers-Danlos Syndrome: A heterogeneous group of autosomally inherited COLLAGEN DISEASES caused by defects in the synthesis or structure of FIBRILLAR COLLAGEN. There are numerous subtypes: classical, hypermobility, vascular, and others. Common clinical features include hyperextensible skin and joints, skin fragility and reduced wound healing capability.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 2 1/4 year-old boy was treated for cystinuria and urolithiasis with high fluid intake, sodium bicarbonate, and D-penicillamine, over a period of 5 3/4 years, unauthorized interruptions and prescribed pauses included." | 7.66 | Skin and bone lesions (dermato-osteolathyrism), possible side effects of D-penicillamine treatment, in a boy with cystinuria. ( Gitzelmann, R; Otten, A; Steinmann, B, 1979) |
| "A 2 1/4 year-old boy was treated for cystinuria and urolithiasis with high fluid intake, sodium bicarbonate, and D-penicillamine, over a period of 5 3/4 years, unauthorized interruptions and prescribed pauses included." | 3.66 | Skin and bone lesions (dermato-osteolathyrism), possible side effects of D-penicillamine treatment, in a boy with cystinuria. ( Gitzelmann, R; Otten, A; Steinmann, B, 1979) |
| "Excellent treatment options exist for Wilson disease, based on copper chelation." | 2.49 | Inborn errors of copper metabolism. ( Kaler, SG, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kaler, SG | 1 |
| Prockop, DJ | 1 |
| Kivirikko, KI | 1 |
| Tuderman, L | 1 |
| Guzman, NA | 1 |
| Siegel, RC | 1 |
| Steinmann, B | 1 |
| Otten, A | 1 |
| Gitzelmann, R | 1 |
| Grahame, R | 1 |
| Harvey, W | 1 |
| Woo, TY | 1 |
| Rasmussen, JE | 1 |
| Charlebois, G | 1 |
| Cadotte, M | 1 |
| Barbeau, A | 1 |
| Eyre, DR | 1 |
2 reviews available for penicillamine and Ehlers-Danlos Syndrome
| Article | Year |
|---|---|
Inborn errors of copper metabolism.
Topics: Chelating Agents; Child; Copper; Cutis Laxa; Ehlers-Danlos Syndrome; Hepatolenticular Degeneration; | 2013 |
Lysyl oxidase.
Topics: Amino Acid Oxidoreductases; Aneurysm; Animals; Chickens; Collagen; Copper; Cutis Laxa; Dogs; Ehlers- | 1979 |
6 other studies available for penicillamine and Ehlers-Danlos Syndrome
| Article | Year |
|---|---|
The biosynthesis of collagen and its disorders (second of two parts).
Topics: Aging; Animals; Colchicine; Collagen; Collagen Diseases; Ehlers-Danlos Syndrome; Glucosyltransferase | 1979 |
Skin and bone lesions (dermato-osteolathyrism), possible side effects of D-penicillamine treatment, in a boy with cystinuria.
Topics: Atrophy; Bicarbonates; Bone and Bones; Bone Diseases; Child, Preschool; Cystinuria; Drug Eruptions; | 1979 |
Cutaneous extensibility in health and disease.
Topics: Acromegaly; Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Collagen; Cutis Laxa; Ehlers-Da | 1975 |
Disorders of transepidermal elimination. Part 1.
Topics: Adolescent; Adult; Aged; Cartilage Diseases; Child; Child, Preschool; Collagen Diseases; Down Syndro | 1985 |
[Cutis hyperelastica following prolonged administration of penicillamine in a patient with Wilson's disease].
Topics: Adolescent; Biopsy; Copper; Ehlers-Danlos Syndrome; Female; Hepatolenticular Degeneration; Humans; P | 1972 |
Collagen defects in genetic disorders of connective tissue.
Topics: Aminopropionitrile; Chemical Phenomena; Chemistry; Collagen; Ehlers-Danlos Syndrome; Homocystinuria; | 1974 |