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penicillamine and Edema

penicillamine has been researched along with Edema in 28 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.

Research Excerpts

ExcerptRelevanceReference
"To determine if a policy of continuing penicillamine therapy in successfully treated patients with rheumatoid arthritis in the presence of persistent proteinuria, was associated or not with resolution of this adverse effect, a computer record of patients receiving penicillamine for rheumatoid arthritis was searched for patients with persistent proteinuria and the case notes of these patients reviewed."7.68Management of proteinuria secondary to penicillamine therapy in rheumatoid arthritis. ( DeSilva, RN; Eastmond, CJ, 1992)
"Experiments were performed in order to ascertain the action of D-penicillamine (PA) on adjuvant arthritis (AA) in rats and to develop a quantitative evaluation method for PA-like drugs, using Lewis, SD, and Wistar rats."7.67Studies of D-penicillamine on strain variability and lymph node cellularity in adjuvant arthritis. ( Aihara, H; Nakaike, S; Otomo, S; Shiono, M; Takeshita, K; Tomita, N, 1985)
"Levamisole potentiated paw oedema induced by carrageenan in the rat whereas penicillamine was without effect."7.66Effects of levamisole and D-penicillamine in rat paw oedema induced by carrageenan and by kaolin. ( Tranter, BC; West, GB, 1979)
"Oedema was measured after the challenging injection."5.26Pertussis vaccine oedema: an experimental model for the action of penicillamine-like drugs. ( Arrigoni-Martelli, E; Bramm, E; Dieppe, PA; Huskisson, EC; Willoughby, DA, 1976)
"In our study the effects of angiotension converting enzyme inhibitor captopril and immunosuppressant agent d-penicillamine were investigated on inflammations mediated by kinins and on adjuvant arthritis in rat paw oedema tests."3.69[Effects pf captopril and D-penicillamine on kinins-mediated and chronic inflammation]. ( Blazsó, G; Gáspár, R, 1996)
"To determine if a policy of continuing penicillamine therapy in successfully treated patients with rheumatoid arthritis in the presence of persistent proteinuria, was associated or not with resolution of this adverse effect, a computer record of patients receiving penicillamine for rheumatoid arthritis was searched for patients with persistent proteinuria and the case notes of these patients reviewed."3.68Management of proteinuria secondary to penicillamine therapy in rheumatoid arthritis. ( DeSilva, RN; Eastmond, CJ, 1992)
"Experiments were performed in order to ascertain the action of D-penicillamine (PA) on adjuvant arthritis (AA) in rats and to develop a quantitative evaluation method for PA-like drugs, using Lewis, SD, and Wistar rats."3.67Studies of D-penicillamine on strain variability and lymph node cellularity in adjuvant arthritis. ( Aihara, H; Nakaike, S; Otomo, S; Shiono, M; Takeshita, K; Tomita, N, 1985)
"The effects of 16 substances, including non-steroidal anti-inflammatory agents, a corticoid, phenols, immunomodulators and gold salts, were studied using two types of acute inflammatory reaction, a non-specific reaction (carrageenan-induced oedema) and an immune reaction (reversed passive Arthus reaction in the rat or active Arthus reaction in the mouse)."3.66Effects of various substances on two types of inflammatory reaction in animals. ( Chevrier, MM; DeFeudis, FV; Hertz, F, 1983)
"Tiopronin (50 mg/kg) and D-penicillamine (50 mg/kg) do not exhibit anti-inflammatory effects in classic animal models (carragenin oedema, granuloma cotton pellets) but suppress pertussis vaccine oedema, an immunological model, when given with a long-lasting dosing regime."3.66Some pharmacological properties of tiopronin. ( Capasso, F, 1981)
"Levamisole potentiated paw oedema induced by carrageenan in the rat whereas penicillamine was without effect."3.66Effects of levamisole and D-penicillamine in rat paw oedema induced by carrageenan and by kaolin. ( Tranter, BC; West, GB, 1979)
"Oedema was measured after the challenging injection."1.26Pertussis vaccine oedema: an experimental model for the action of penicillamine-like drugs. ( Arrigoni-Martelli, E; Bramm, E; Dieppe, PA; Huskisson, EC; Willoughby, DA, 1976)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199019 (67.86)18.7374
1990's3 (10.71)18.2507
2000's5 (17.86)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gucev, ZS1
Pop-Jordanova, N1
Calovska, V1
Tasic, V1
Slavevska, N1
Laban, N1
Noli, MC1
Lepori, MB1
Loudianos, G1
Fernandes, D1
Da Silva-Santos, JE1
Assreuy, J1
Khattab, MM1
Hertz, F1
Chevrier, MM1
DeFeudis, FV1
Capasso, F2
Mascolo, N1
Autore, G1
Tanphaichitr, K1
Gáspár, R1
Blazsó, G1
Nishino, T1
Watanabe, S1
Oyama, H1
Fukuya, Y1
Hayashi, N1
Kobayashi, M1
King, TS1
Chinchilli, VM1
Hawkes, ND1
Mutimer, D1
Thomas, GA1
Beirith, A1
Santos, AR1
Calixto, JB1
Hauftová, D1
Arrigoni-Martelli, E2
Vince, JD1
Ashford, RW1
Gratten, MJ1
Bana-Koiri, J1
Tranter, BC1
West, GB1
Bramm, E1
Huskisson, EC1
Willoughby, DA1
Dieppe, PA1
Friedrich, L1
Zimmermann, F1
DeSilva, RN1
Eastmond, CJ1
Mercurio, SD1
Combs, GF1
Beveridge, SJ1
Garrett, IR1
Whitehouse, MW1
Vernon-Roberts, B1
Brooks, PM1
Nakaike, S1
Takeshita, K1
Shiono, M1
Tomita, N1
Otomo, S1
Aihara, H1
Civatte, J1
Belaich, S1
Blanchet, P1
Kienecker, B1
Steinetz, B1
Giannina, T1
Butler, M1
Mörsdorf, K1
Knippertz, T1
Rausch, KD1
Domenjoz, R1
Stephens, AD1
Watts, RW1
Sancilio, LF1

Reviews

1 review available for penicillamine and Edema

ArticleYear
[Dermatology from 1969 to 1973].
    La Revue du praticien, 1974, Apr-21, Volume: 24, Issue:23

    Topics: Agammaglobulinemia; Blood Protein Disorders; Bromides; Candidiasis, Cutaneous; Carcinoid Tumor; Derm

1974

Trials

1 trial available for penicillamine and Edema

ArticleYear
The treatment of cystinuria with N-acetyl-D-penicillamine, a comparison with the results of D-penicillamine treatment.
    The Quarterly journal of medicine, 1971, Volume: 40, Issue:159

    Topics: Acylation; Adolescent; Adult; Child; Cysteine; Cystinuria; Desensitization, Immunologic; Drug Hypers

1971

Other Studies

26 other studies available for penicillamine and Edema

ArticleYear
Acute Gallbladder Hydrops and Arthritis: unusual initial manifestations of Wilson's Disease (WD): Case Report.
    Prilozi, 2011, Volume: 32, Issue:2

    Topics: Adenosine Triphosphatases; Arthritis; Cation Transport Proteins; Ceruloplasmin; Chelating Agents; Ch

2011
Nitric oxide-induced inhibition of mouse paw edema: involvement of soluble guanylate cyclase and potassium channels.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2002, Volume: 51, Issue:8

    Topics: Animals; Blood Pressure; Bradykinin; Carrageenan; Dextran Sulfate; Edema; Female; Guanylate Cyclase;

2002
TEMPOL, a membrane-permeable radical scavenger, attenuates peroxynitrite- and superoxide anion-enhanced carrageenan-induced paw edema and hyperalgesia: a key role for superoxide anion.
    European journal of pharmacology, 2006, Oct-24, Volume: 548, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cyclic N-Oxides; Edema; Enzyme Inhibitors; Foot; Fre

2006
Effects of various substances on two types of inflammatory reaction in animals.
    General pharmacology, 1983, Volume: 14, Issue:4

    Topics: Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Arthus Reaction; Butylated Hydroxytoluen

1983
The effects of levamisole and D-penicillamine on some inflammatory models in vivo and on PG production in vitro.
    Pharmacological research communications, 1981, Volume: 13, Issue:4

    Topics: Animals; Disease Models, Animal; Edema; In Vitro Techniques; Indomethacin; Inflammation; Leukocytes;

1981
Some pharmacological properties of tiopronin.
    Agents and actions, 1981, Volume: 11, Issue:6-7

    Topics: Amino Acids, Sulfur; Animals; Anti-Inflammatory Agents; Carrageenan; Edema; Gossypium; Granuloma; Le

1981
D-penicillamine-induced bronchial spasm.
    Southern medical journal, 1980, Volume: 73, Issue:6

    Topics: Adolescent; Arthritis, Rheumatoid; Bronchial Spasm; Edema; Female; Humans; Male; Middle Aged; Penici

1980
[Effects pf captopril and D-penicillamine on kinins-mediated and chronic inflammation].
    Acta pharmaceutica Hungarica, 1996, Volume: 66, Issue:4

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Arthritis, Experimental; Bradykinin; Capillaries;

1996
An endothelial nitric oxide synthase inhibitor aggravates CDL-induced acute pancreatitis in rats.
    Pancreas, 1999, Volume: 19, Issue:4

    Topics: Acute Disease; Animals; Arginine; Ascitic Fluid; Duodenum; Edema; Enzyme Inhibitors; Guanidines; Lig

1999
A generalized concordance correlation coefficient for continuous and categorical data.
    Statistics in medicine, 2001, Jul-30, Volume: 20, Issue:14

    Topics: Computer Simulation; Confidence Intervals; Data Interpretation, Statistical; Edema; Female; Humans;

2001
Generalised oedema, lethargy, personality disturbance, and recurring nightmares in a young girl.
    Postgraduate medical journal, 2001, Volume: 77, Issue:910

    Topics: Adolescent; Biopsy; Ceruloplasmin; Chelating Agents; Copper; Edema; Female; Hepatolenticular Degener

2001
Mechanisms underlying the nociception and paw oedema caused by injection of glutamate into the mouse paw.
    Brain research, 2002, Jan-11, Volume: 924, Issue:2

    Topics: Animals; Azo Compounds; Coloring Agents; Dizocilpine Maleate; Dose-Response Relationship, Drug; Edem

2002
[Adverse effects of penicillamine].
    Vnitrni lekarstvi, 1978, Volume: 24, Issue:3

    Topics: Adult; Drug Eruptions; Edema; Female; Humans; Male; Penicillamine; Proteinuria

1978
Penicillamine in experimental models of immunologically mediated inflammation.
    Agents and actions. Supplements, 1979, Issue:5

    Topics: Animals; Arthritis; Arthritis, Experimental; Edema; Levamisole; Penicillamine; Pertussis Vaccine; Ra

1979
Strongyloides species infestation in young infants of papu, New Guinea: association with generalized oedema.
    Papua and New Guinea medical journal, 1979, Volume: 22, Issue:2

    Topics: Blood Transfusion; Chloramphenicol; Edema; Female; Humans; Infant; Infant, Newborn; Male; New Guinea

1979
Effects of levamisole and D-penicillamine in rat paw oedema induced by carrageenan and by kaolin.
    International archives of allergy and applied immunology, 1979, Volume: 59, Issue:3

    Topics: Animals; Carrageenan; Edema; Female; Inflammation; Kaolin; Levamisole; Male; Penicillamine; Rats

1979
Pertussis vaccine oedema: an experimental model for the action of penicillamine-like drugs.
    Agents and actions, 1976, Volume: 6, Issue:5

    Topics: Animals; Disease Models, Animal; Drug Administration Schedule; Edema; Female; Freund's Adjuvant; Hyp

1976
[Pharmacology of D-penicillamine].
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:2

    Topics: Administration, Oral; Animals; Biomechanical Phenomena; Burns; Edema; Elasticity; Female; Granulatio

1975
Management of proteinuria secondary to penicillamine therapy in rheumatoid arthritis.
    Clinical rheumatology, 1992, Volume: 11, Issue:2

    Topics: Arthritis, Rheumatoid; Edema; Humans; Penicillamine; Proteinuria

1992
Synthetic seleno-organic compound with glutathione peroxidase-like activity in the chick.
    Biochemical pharmacology, 1986, Dec-15, Volume: 35, Issue:24

    Topics: Animals; Aurothioglucose; Azoles; Chickens; Edema; Glutathione Peroxidase; Isoindoles; Liver; NADP;

1986
Biodistribution of 64Cu in inflamed rats following administration of two anti-inflammatory copper complexes.
    Agents and actions, 1985, Volume: 17, Issue:1

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Carrageenan; Copper; Edema; Granuloma; I

1985
Studies of D-penicillamine on strain variability and lymph node cellularity in adjuvant arthritis.
    Agents and actions, 1985, Volume: 16, Issue:6

    Topics: Animals; Arthritis; Arthritis, Experimental; Cell Division; Edema; Female; Gold Sodium Thiomalate; L

1985
[D-Penicillamine in adjuvant arthritis of rats].
    Die Medizinische Welt, 1974, Sep-27, Volume: 25, Issue:39

    Topics: Adjuvants, Immunologic; Animals; Arthritis, Rheumatoid; Dose-Response Relationship, Drug; Edema; Fem

1974
The role of sulfhydryl groups in three models of inflammatory disease.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 185, Issue:1

    Topics: Animals; Arthritis; Carrageenan; Croton Oil; Cyclophosphamide; Cysteine; Dexamethasone; Disulfides;

1973
Studies on the antiphlogistic activity of cytostatics.
    Pharmacology, 1972, Volume: 7, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Antimetabolites; Carrageenan; Chloramphenicol; Cyclophosphamide;

1972
Evans blue-carrageenan pleural effusion as a model for the assay of nonsteroidal antirheumatic drugs.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 168, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Carrageenan; Chloroquine; Coloring Agents; Ed

1969