penicillamine has been researched along with Dystonia in 8 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The generalized dystonia improved in the following 3 months and 3 years respectively in 2 patients." | 5.30 | Acute dystonia with thalamic and brainstem lesions after initial penicillamine treatment in Wilson's disease. ( Chu, NS; Huang, CC, 1998) |
| "The clinical manifestations of Wilson disease (WD) are varied and challenging." | 1.34 | Wilson disease: description of 282 patients evaluated over 3 decades. ( Arunodaya, GR; Meenakshi-Sundaram, S; Sinha, S; Swamy, HS; Taly, AB, 2007) |
| "A 37-year-old man with Wilson's disease is described, in whom the introduction of penicillamine therapy was followed after 3." | 1.31 | Penicillamine-induced lethal status dystonicus in a patient with Wilson's disease. ( Kostić, VS; Pejović, S; Sternić, N; Svetel, M, 2001) |
| "We conclude that Wilson's disease may be a good indication for LTX for both neurological manifestation with stable liver function and hepatic manifestation with cirrhosis or acute liver failure." | 1.30 | Liver transplantation: treatment of choice for hepatic and neurological manifestation of Wilson's disease. ( Bechstein, WO; Becker, M; Luck, W; Mueller, AR; Neuhaus, P; Neuhaus, R; Platz, KP; Schuelke, M; Schumacher, G; Steinmüller, T, 1997) |
| "The generalized dystonia improved in the following 3 months and 3 years respectively in 2 patients." | 1.30 | Acute dystonia with thalamic and brainstem lesions after initial penicillamine treatment in Wilson's disease. ( Chu, NS; Huang, CC, 1998) |
| "All patients had dystonia as their major clinical manifestation but also had dysarthria and at the presentation of the disease had choreoathetoid movements in at least one limb." | 1.29 | Neurological Wilson's disease studied with magnetic resonance imaging and with positron emission tomography using dopaminergic markers. ( Andersson, Y; Aquilonius, SM; Hartvig, P; Hörnfeldt, K; Långström, B; Tedroff, J; Thuomas, KA; Westermark, K, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Samanci, B | 1 |
| Sahin, E | 1 |
| Bilgic, B | 1 |
| Tufekcioglu, Z | 1 |
| Gurvit, H | 1 |
| Emre, M | 1 |
| Demir, K | 1 |
| Hanagasi, HA | 1 |
| Thapa, R | 1 |
| Ghosh, A | 1 |
| Taly, AB | 1 |
| Meenakshi-Sundaram, S | 1 |
| Sinha, S | 1 |
| Swamy, HS | 1 |
| Arunodaya, GR | 1 |
| Suda, M | 1 |
| Kubota, J | 1 |
| Yamaguchi, Y | 1 |
| Fujioka, Y | 1 |
| Saito, Y | 1 |
| Aoki, T | 1 |
| Westermark, K | 1 |
| Tedroff, J | 1 |
| Thuomas, KA | 1 |
| Hartvig, P | 1 |
| Långström, B | 1 |
| Andersson, Y | 1 |
| Hörnfeldt, K | 1 |
| Aquilonius, SM | 1 |
| Schumacher, G | 1 |
| Platz, KP | 1 |
| Mueller, AR | 1 |
| Neuhaus, R | 1 |
| Steinmüller, T | 1 |
| Bechstein, WO | 1 |
| Becker, M | 1 |
| Luck, W | 1 |
| Schuelke, M | 1 |
| Neuhaus, P | 1 |
| Huang, CC | 1 |
| Chu, NS | 1 |
| Svetel, M | 1 |
| Sternić, N | 1 |
| Pejović, S | 1 |
| Kostić, VS | 1 |
8 other studies available for penicillamine and Dystonia
| Article | Year |
|---|---|
Neurological features and outcomes of Wilson's disease: a single-center experience.
Topics: Copper; Dystonia; Female; Hepatolenticular Degeneration; Humans; Male; Penicillamine; Tremor | 2021 |
'Face of the giant panda' sign in Wilson disease.
Topics: Adolescent; Arm; Brain; Chelating Agents; Dystonia; Follow-Up Studies; Hepatolenticular Degeneration | 2008 |
Wilson disease: description of 282 patients evaluated over 3 decades.
Topics: Adolescent; Adult; Athetosis; Brain; Ceruloplasmin; Chelating Agents; Child; Child, Preschool; Chore | 2007 |
[A study of trientine therapy in Wilson's disease with neurological symptoms].
Topics: Adolescent; Adult; Dysarthria; Dystonia; Female; Hepatolenticular Degeneration; Humans; Male; Penici | 1993 |
Neurological Wilson's disease studied with magnetic resonance imaging and with positron emission tomography using dopaminergic markers.
Topics: Adult; Anti-Bacterial Agents; Binding Sites; Brain; Caudate Nucleus; Ceruloplasmin; Copper; Corpus S | 1995 |
Liver transplantation: treatment of choice for hepatic and neurological manifestation of Wilson's disease.
Topics: Adolescent; Adult; Anemia, Hemolytic; Ataxia; Chelating Agents; Deglutition Disorders; Dysarthria; D | 1997 |
Acute dystonia with thalamic and brainstem lesions after initial penicillamine treatment in Wilson's disease.
Topics: Adolescent; Adult; Brain Stem; Dystonia; Female; Hepatolenticular Degeneration; Humans; Magnetic Res | 1998 |
Penicillamine-induced lethal status dystonicus in a patient with Wilson's disease.
Topics: Acute Kidney Injury; Adult; Chelating Agents; Dystonia; Fatal Outcome; Hepatolenticular Degeneration | 2001 |