Page last updated: 2024-11-07

penicillamine and Dystonia

penicillamine has been researched along with Dystonia in 8 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Dystonia: An attitude or posture due to the co-contraction of agonists and antagonist muscles in one region of the body. It most often affects the large axial muscles of the trunk and limb girdles. Conditions which feature persistent or recurrent episodes of dystonia as a primary manifestation of disease are referred to as DYSTONIC DISORDERS. (Adams et al., Principles of Neurology, 6th ed, p77)

Research Excerpts

ExcerptRelevanceReference
"The generalized dystonia improved in the following 3 months and 3 years respectively in 2 patients."5.30Acute dystonia with thalamic and brainstem lesions after initial penicillamine treatment in Wilson's disease. ( Chu, NS; Huang, CC, 1998)
"The clinical manifestations of Wilson disease (WD) are varied and challenging."1.34Wilson disease: description of 282 patients evaluated over 3 decades. ( Arunodaya, GR; Meenakshi-Sundaram, S; Sinha, S; Swamy, HS; Taly, AB, 2007)
"A 37-year-old man with Wilson's disease is described, in whom the introduction of penicillamine therapy was followed after 3."1.31Penicillamine-induced lethal status dystonicus in a patient with Wilson's disease. ( Kostić, VS; Pejović, S; Sternić, N; Svetel, M, 2001)
"We conclude that Wilson's disease may be a good indication for LTX for both neurological manifestation with stable liver function and hepatic manifestation with cirrhosis or acute liver failure."1.30Liver transplantation: treatment of choice for hepatic and neurological manifestation of Wilson's disease. ( Bechstein, WO; Becker, M; Luck, W; Mueller, AR; Neuhaus, P; Neuhaus, R; Platz, KP; Schuelke, M; Schumacher, G; Steinmüller, T, 1997)
"The generalized dystonia improved in the following 3 months and 3 years respectively in 2 patients."1.30Acute dystonia with thalamic and brainstem lesions after initial penicillamine treatment in Wilson's disease. ( Chu, NS; Huang, CC, 1998)
"All patients had dystonia as their major clinical manifestation but also had dysarthria and at the presentation of the disease had choreoathetoid movements in at least one limb."1.29Neurological Wilson's disease studied with magnetic resonance imaging and with positron emission tomography using dopaminergic markers. ( Andersson, Y; Aquilonius, SM; Hartvig, P; Hörnfeldt, K; Långström, B; Tedroff, J; Thuomas, KA; Westermark, K, 1995)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (50.00)18.2507
2000's3 (37.50)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Samanci, B1
Sahin, E1
Bilgic, B1
Tufekcioglu, Z1
Gurvit, H1
Emre, M1
Demir, K1
Hanagasi, HA1
Thapa, R1
Ghosh, A1
Taly, AB1
Meenakshi-Sundaram, S1
Sinha, S1
Swamy, HS1
Arunodaya, GR1
Suda, M1
Kubota, J1
Yamaguchi, Y1
Fujioka, Y1
Saito, Y1
Aoki, T1
Westermark, K1
Tedroff, J1
Thuomas, KA1
Hartvig, P1
Långström, B1
Andersson, Y1
Hörnfeldt, K1
Aquilonius, SM1
Schumacher, G1
Platz, KP1
Mueller, AR1
Neuhaus, R1
Steinmüller, T1
Bechstein, WO1
Becker, M1
Luck, W1
Schuelke, M1
Neuhaus, P1
Huang, CC1
Chu, NS1
Svetel, M1
Sternić, N1
Pejović, S1
Kostić, VS1

Other Studies

8 other studies available for penicillamine and Dystonia

ArticleYear
Neurological features and outcomes of Wilson's disease: a single-center experience.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2021, Volume: 42, Issue:9

    Topics: Copper; Dystonia; Female; Hepatolenticular Degeneration; Humans; Male; Penicillamine; Tremor

2021
'Face of the giant panda' sign in Wilson disease.
    Pediatric radiology, 2008, Volume: 38, Issue:12

    Topics: Adolescent; Arm; Brain; Chelating Agents; Dystonia; Follow-Up Studies; Hepatolenticular Degeneration

2008
Wilson disease: description of 282 patients evaluated over 3 decades.
    Medicine, 2007, Volume: 86, Issue:2

    Topics: Adolescent; Adult; Athetosis; Brain; Ceruloplasmin; Chelating Agents; Child; Child, Preschool; Chore

2007
[A study of trientine therapy in Wilson's disease with neurological symptoms].
    No to hattatsu = Brain and development, 1993, Volume: 25, Issue:5

    Topics: Adolescent; Adult; Dysarthria; Dystonia; Female; Hepatolenticular Degeneration; Humans; Male; Penici

1993
Neurological Wilson's disease studied with magnetic resonance imaging and with positron emission tomography using dopaminergic markers.
    Movement disorders : official journal of the Movement Disorder Society, 1995, Volume: 10, Issue:5

    Topics: Adult; Anti-Bacterial Agents; Binding Sites; Brain; Caudate Nucleus; Ceruloplasmin; Copper; Corpus S

1995
Liver transplantation: treatment of choice for hepatic and neurological manifestation of Wilson's disease.
    Clinical transplantation, 1997, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Anemia, Hemolytic; Ataxia; Chelating Agents; Deglutition Disorders; Dysarthria; D

1997
Acute dystonia with thalamic and brainstem lesions after initial penicillamine treatment in Wilson's disease.
    European neurology, 1998, Volume: 39, Issue:1

    Topics: Adolescent; Adult; Brain Stem; Dystonia; Female; Hepatolenticular Degeneration; Humans; Magnetic Res

1998
Penicillamine-induced lethal status dystonicus in a patient with Wilson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2001, Volume: 16, Issue:3

    Topics: Acute Kidney Injury; Adult; Chelating Agents; Dystonia; Fatal Outcome; Hepatolenticular Degeneration

2001