Page last updated: 2024-11-07

penicillamine and Drug Hypersensitivity

penicillamine has been researched along with Drug Hypersensitivity in 70 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.

Research Excerpts

ExcerptRelevanceReference
"The anti-rheumatoid drug D-penicillamine (D-pen) has a reactive sulfhydryl group capable of modifying self antigens, and can provoke typical autoantibody-mediated myasthenia gravis (MG), especially in DR1+ individuals."7.70T cell responses to D-penicillamine in drug-induced myasthenia gravis: recognition of modified DR1:peptide complexes. ( Hill, M; Moss, P; Newsom-Davis, J; Willcox, N; Wordsworth, P, 1999)
"25 serum samples of 22 patients with primary biliary cirrhosis (15 under or after treatment with D-penicillamine) were tested for antibodies against D-penicillamine."7.68[Antibodies against D-penicillamine in primary biliary cirrhosis]. ( Storch, W, 1990)
"Six patients with rheumatoid arthritis developed a syndrome resembling lupus erythematosus while being treated with penicillamine."7.66Systemic lupus erythematosus during penicillamine therapy for rheumatoid arthritis. ( Chalmers, A; Patterson, AC; Reid, G; Stein, HE; Thompson, D, 1982)
"Intraperitoneal gelatin sponge implants were used in guinea-pigs to examine the effect of D-penicillamine on the delayed hypersensitivity reaction in vivo."7.66D-penicillamine-induced enhancement of the delayed hypersensitivity reaction in guinea-pigs. ( Honma, T; Nakayama, Y, 1982)
"Following one-week treatment with D-penicillamine for rheumatoid arthritis a seven-year-old girl died with the clinical features of protracted circulatory shock."7.66[Administration of D-penicillamine instead of penicillin with fatal results: allergy of the delayed type with protracted shock as fatal complication of treatment with D-penicillamine for rheumatoid arthritis in a child (author's transl)]. ( Adebahr, G; Erkrath, KD; Klöppel, A, 1980)
"The anti-rheumatoid drug D-penicillamine (D-pen) has a reactive sulfhydryl group capable of modifying self antigens, and can provoke typical autoantibody-mediated myasthenia gravis (MG), especially in DR1+ individuals."3.70T cell responses to D-penicillamine in drug-induced myasthenia gravis: recognition of modified DR1:peptide complexes. ( Hill, M; Moss, P; Newsom-Davis, J; Willcox, N; Wordsworth, P, 1999)
"25 serum samples of 22 patients with primary biliary cirrhosis (15 under or after treatment with D-penicillamine) were tested for antibodies against D-penicillamine."3.68[Antibodies against D-penicillamine in primary biliary cirrhosis]. ( Storch, W, 1990)
"Six patients with rheumatoid arthritis developed a syndrome resembling lupus erythematosus while being treated with penicillamine."3.66Systemic lupus erythematosus during penicillamine therapy for rheumatoid arthritis. ( Chalmers, A; Patterson, AC; Reid, G; Stein, HE; Thompson, D, 1982)
"Intraperitoneal gelatin sponge implants were used in guinea-pigs to examine the effect of D-penicillamine on the delayed hypersensitivity reaction in vivo."3.66D-penicillamine-induced enhancement of the delayed hypersensitivity reaction in guinea-pigs. ( Honma, T; Nakayama, Y, 1982)
"Following one-week treatment with D-penicillamine for rheumatoid arthritis a seven-year-old girl died with the clinical features of protracted circulatory shock."3.66[Administration of D-penicillamine instead of penicillin with fatal results: allergy of the delayed type with protracted shock as fatal complication of treatment with D-penicillamine for rheumatoid arthritis in a child (author's transl)]. ( Adebahr, G; Erkrath, KD; Klöppel, A, 1980)
"18 patients with Wilson's disease with and without proteinuria and 19 test persons without Wilson's disease were examined for a disturbance of the transformation on account of phythemagglutinin, streptolysin-O and several D-penicillamine preparations by means of the lymphocyte transformation test."3.66[Immunologic studies with the lymphocyte transformation test on the side effects of D-penicillamine therapy in Wilson's disease]. ( Berger, H; Storch, W, 1980)
"In a 53-year-old woman an acute allergic thrombocytopenia (acute Werlhf's disease) occurred after treatment with D-penicillamine for one month which led to death."3.65[Severe side-effects of treatment with D-penicillamine (author's transl)]. ( Hennemann, HH; Hubertus, H; Stocker, WG, 1975)
" During the treatment, clinical observations and 24-h urine copper excretion as well as adverse effects of medicines were recorded and analyzed."1.39Clinical efficacy and safety of chelation treatment with typical penicillamine in cross combination with DMPS repeatedly for Wilson's disease. ( Chen, L; Fang, F; Li, XF; Liu, Y; Xu, SQ; Zhu, HY, 2013)
"The effects of different antirheumatic drugs administered according to various dosing regimes on tuberculin hypersensitivity in rats have been assessed quantitating the changes of exudate volume and mononuclear cells immigration at the site of challenge."1.26Delayed hypersensitivity to tuberculin in rats: effects of antirheumatic drugs. ( Arrigoni-Martelli, E; Binderup, L; Bramm, E, 1979)

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-199054 (77.14)18.7374
1990's12 (17.14)18.2507
2000's1 (1.43)29.6817
2010's2 (2.86)24.3611
2020's1 (1.43)2.80

Authors

AuthorsStudies
Zhu, XQ1
Li, LY1
Yang, WM1
Wang, Y1
Lian, X1
Yan, B1
Xu, SQ1
Li, XF1
Zhu, HY1
Liu, Y1
Fang, F1
Chen, L1
WILLIAMSON, CI1
BLAKEY, CL1
LITTLE, SC1
DEMPSEY, H1
BRANSCOMB, BV1
BUTTERWORTH, CE1
PITTMAN, JA1
ZEH, E1
ADAMS, DA1
GOLDMAN, R1
MAXWELL, MH1
LATTA, H1
BUDD, MA1
PARKER, CW1
NORDEN, CW1
HIRSCHMAN, SZ1
ISSELBACHER, KJ1
Nierkens, S1
Aalbers, M1
Bol, M1
Bleumink, R1
van Kooten, P1
Boon, L1
Pieters, R1
Edwards, RG1
Spackman, DA1
Dewdney, JM1
Chalès, G1
Fauchet, R1
Pawlotsky, Y1
Gueguen, M1
Coutard, J1
Duval, A1
Pittie, P1
Bell, CL1
Graziano, FM1
Heymans, G1
Soupart, A1
Chalmers, A1
Thompson, D1
Stein, HE1
Reid, G1
Patterson, AC1
Honma, T1
Nakayama, Y1
Seibold, JR1
Lynch, CJ1
Medsger, TA1
Murphy, KC1
Atkins, CJ1
Offer, RC1
Hogg, JC1
Stein, HB1
Ruenitz, PC1
Sorenson, JR1
West, GB1
Haneke, EG1
Körner, E1
Haneke, E1
Erkrath, KD1
Adebahr, G1
Klöppel, A1
Storch, W3
Berger, H1
Chan, CY1
Baker, AL1
Takeuchi, F1
Nakano, K1
Yamada, H1
Kosuge, E1
Hirai, M1
Maeda, H1
Moroi, Y1
Keeble, E1
Cooke, SW1
Coleman, JW3
Hill, M1
Moss, P1
Wordsworth, P1
Newsom-Davis, J1
Willcox, N1
Cole, P1
Newbold, PC1
Bramm, E1
Binderup, L1
Arrigoni-Martelli, E1
Krel', AA1
Ivanova, TS1
Juhlin, L1
Ahlstedt, S1
Andal, L1
Ekström, B1
Svärd, PO1
Wide, L1
Walshe, JM1
Rabenalt, P1
Wysocka, K1
Praszek, B1
Hennemann, HH1
Hubertus, H1
Stocker, WG1
O'Donnell, CA1
Bannwarth, B1
Schaeverbeke, T1
Dehais, J1
Sany, J1
Combe, B1
Verdie-Petibon, D1
Tagemouati, A1
Daures, JP1
Ishii, N1
Ichiyama, S1
Ishii, T1
Aoki, I1
Okuda, K1
Nakajima, H1
Adler, SG1
Cohen, AH1
Border, WA1
Ritland, S1
Umeki, S1
Ohga, R1
Konishi, Y1
Yasuda, T1
Morimoto, K1
Terao, A1
Bach, GL1
Wildhirt, E1
Merrill, JP1
Assem, ES1
Vickers, MR1
Kuffer, R1
Noble, JP1
Wallnöfer, H1
Hanusch, M1
Amos, HE1
Gros, H1
Zwirner, K1
Herzog, W1
Oliver, L1
Liberman, AU1
De Vries, A1
Witzgall, H1
St George, IM1
Rau, R1
Weber, S1
Böni, A1
Oliver, I1
Liberman, UA1
DeVries, A1
Fulghum, DD1
Katz, R1
Ledvina, M1
Ellederová, D1
Metz, G1
Pevny, I1
Metz, J1
Stephens, AD1
Watts, RW2
Thivolet, J1
Perrot, H1
François, R1
Hayslett, JP1
Bensch, KG1
Kashgarian, M1
Rosenberg, LE1
Scheinberg, IH1
Amos, H1
Crawhall, JC1
Negreiros, EB1

Reviews

7 reviews available for penicillamine and Drug Hypersensitivity

ArticleYear
[Drug-induced pneumopathies (excluding anticancer drugs)].
    Revue medicale de Bruxelles, 1984, Volume: 5, Issue:4

    Topics: Antigen-Antibody Complex; Complement Activation; Drug Hypersensitivity; Humans; Lung; Lung Diseases;

1984
Protein haptenation by drugs.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1998, Volume: 28 Suppl 4

    Topics: Animals; Antirheumatic Agents; Carrier Proteins; Drug Hypersensitivity; Haptens; Humans; Penicillami

1998
Drug-induced lung disease.
    Drugs, 1977, Volume: 13, Issue:6

    Topics: Bronchial Spasm; Dermatomyositis; Drug Hypersensitivity; Humans; Immunity; Immunoglobulin E; Iodides

1977
[Clinical use of d-penicillamine, complications and possibilities of their prevention].
    Terapevticheskii arkhiv, 1977, Volume: 49, Issue:10

    Topics: Collagen Diseases; Dose-Response Relationship, Drug; Drug Eruptions; Drug Evaluation; Drug Hypersens

1977
Allergic reactions to drugs: current concepts and problems.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1990, Volume: 20, Issue:1

    Topics: Antibodies; B-Lymphocytes; Captopril; Drug Hypersensitivity; Humans; Molecular Weight; Penicillamine

1990
Hypersensitivity phenomena and the kidney: role of drugs and environmental agents.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1985, Volume: 5, Issue:2

    Topics: Animals; Anti-Glomerular Basement Membrane Disease; Anti-Inflammatory Agents; Antibodies; Captopril;

1985
Glomerulonephritis (second of three parts).
    The New England journal of medicine, 1974, Feb-07, Volume: 290, Issue:6

    Topics: Anti-Glomerular Basement Membrane Disease; Cryoglobulins; Drug Hypersensitivity; Endocarditis, Subac

1974

Trials

2 trials available for penicillamine and Drug Hypersensitivity

ArticleYear
[Treatment of chronic hepatitis with immunosuppressive agents and D-penicillamine].
    Wiener medizinische Wochenschrift (1946), 1973, Jun-23, Volume: 123, Issue:25

    Topics: Agranulocytosis; Azathioprine; Chronic Disease; Clinical Trials as Topic; Drug Hypersensitivity; Fem

1973
The treatment of cystinuria with N-acetyl-D-penicillamine, a comparison with the results of D-penicillamine treatment.
    The Quarterly journal of medicine, 1971, Volume: 40, Issue:159

    Topics: Acylation; Adolescent; Adult; Child; Cysteine; Cystinuria; Desensitization, Immunologic; Drug Hypers

1971

Other Studies

61 other studies available for penicillamine and Drug Hypersensitivity

ArticleYear
Combined dimercaptosuccinic acid and zinc treatment in neurological Wilson's disease patients with penicillamine-induced allergy or early neurological deterioration.
    Bioscience reports, 2020, 08-28, Volume: 40, Issue:8

    Topics: Adolescent; Adult; Brain; Chelating Agents; Child; Disease Progression; Drug Hypersensitivity; Drug

2020
Diagnosis of penicillin allergy: a MOFs-based composite hydrogel for detecting β-lactamase in serum.
    Chemical communications (Cambridge, England), 2018, Dec-20, Volume: 55, Issue:2

    Topics: Alginates; beta-Lactamases; Drug Hypersensitivity; Europium; Humans; Hydrogels; Iron; Limit of Detec

2018
Clinical efficacy and safety of chelation treatment with typical penicillamine in cross combination with DMPS repeatedly for Wilson's disease.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2013, Volume: 33, Issue:5

    Topics: Administration, Oral; Adolescent; Chelating Agents; Chelation Therapy; Child; Copper; Drug Administr

2013
MEDICAL GRAND ROUNDS FROM THE UNIVERSITY OF ALABAMA MEDICAL CENTER. CASE 9: WILSON'S DISEASE.
    Southern medical journal, 1963, Volume: 56

    Topics: Chelating Agents; Drug Hypersensitivity; Hepatolenticular Degeneration; Humans; Penicillamine; Teach

1963
[THE SYMPTOMS OF MYOCARDITIS DUE TO DRUG ALLERGY].
    Allergie und Asthma, 1963, Volume: 9

    Topics: Antitussive Agents; Aspirin; Caffeine; Cardiac Complexes, Premature; Chloramphenicol; Drug Hypersens

1963
NEPHROTIC SYNDROME ASSOCIATED WITH PENICILLAMINE THERAPY OF WILSON'S DISEASE.
    The American journal of medicine, 1964, Volume: 36

    Topics: Biopsy; Dermatology; Drug Hypersensitivity; Glomerulonephritis; Hepatolenticular Degeneration; Human

1964
EVALUATION OF INTRADERMAL SKIN TESTS IN PENICILLIN HYPERSENSITIVITY.
    JAMA, 1964, Oct-19, Volume: 190

    Topics: Antigens; Biomedical Research; Drug Hypersensitivity; Ethylenediamines; Humans; Male; Penicillamine;

1964
THE NEPHROTIC SYNDROME AS A COMPLICATION OF PENICILLAMINE THERAPY FOR HEPATOLENTICULAR DEGENERATION (WILSON'S DISEASE).
    Annals of internal medicine, 1965, Volume: 62

    Topics: Drug Hypersensitivity; Drug Therapy; Hepatolenticular Degeneration; Humans; Hypersensitivity, Delaye

1965
Differential requirement for CD28/CTLA-4-CD80/CD86 interactions in drug-induced type 1 and type 2 immune responses to trinitrophenyl-ovalbumin.
    Journal of immunology (Baltimore, Md. : 1950), 2005, Sep-15, Volume: 175, Issue:6

    Topics: Animals; Antibodies; Antigens, CD; Antigens, Differentiation; B7-1 Antigen; Bystander Effect; CD28 A

2005
Development and use of three new radioallergosorbent tests in the diagnosis of penicillin allergy.
    International archives of allergy and applied immunology, 1982, Volume: 68, Issue:4

    Topics: Chemical Phenomena; Chemistry; Drug Hypersensitivity; Dyspnea; Epitopes; Humans; Immunoglobulin E; O

1982
[The HLA-DR determinants in chronic inflammatory rheumatism].
    Revue du rhumatisme et des maladies osteo-articulaires, 1983, Volume: 50, Issue:7

    Topics: Adult; Aged; Arthritis, Rheumatoid; Chondrocalcinosis; Drug Hypersensitivity; Epitopes; Female; Gold

1983
The safety of administration of penicillamine to penicillin-sensitive individuals.
    Arthritis and rheumatism, 1983, Volume: 26, Issue:6

    Topics: Adult; Aged; Benzeneacetamides; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Penicillam

1983
Systemic lupus erythematosus during penicillamine therapy for rheumatoid arthritis.
    Annals of internal medicine, 1982, Volume: 97, Issue:5

    Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Hypersensitivity; Female; Histocompatibility Antigens Class

1982
D-penicillamine-induced enhancement of the delayed hypersensitivity reaction in guinea-pigs.
    Annals of the rheumatic diseases, 1982, Volume: 41, Issue:1

    Topics: Animals; Ascitic Fluid; Chemotaxis; Drug Hypersensitivity; Exudates and Transudates; Female; Guinea

1982
Cholestasis associated with D-penicillamine therapy: case report and review of the literature.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:3

    Topics: Adult; Arthritis, Rheumatoid; Cholestasis; Drug Hypersensitivity; Eosinophils; Female; Humans; Leuko

1981
Obliterative bronchiolitis in two rheumatoid arthritis patients treated with penicillamine.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:3

    Topics: Arthritis, Rheumatoid; Bronchitis; Drug Hypersensitivity; Female; Humans; Middle Aged; Necrosis; Pen

1981
Skin reactions of rats to levamisole and D-penicillamine.
    International archives of allergy and applied immunology, 1980, Volume: 61, Issue:1

    Topics: Animals; Drug Hypersensitivity; Female; Hypersensitivity, Delayed; Intradermal Tests; Levamisole; Ma

1980
[Clinical significance of positive penicillin test reactions (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, May-02, Volume: 105, Issue:18

    Topics: Ampicillin; Chronic Disease; Drug Hypersensitivity; Humans; Lymphocyte Activation; Penicillamine; Pe

1980
[Administration of D-penicillamine instead of penicillin with fatal results: allergy of the delayed type with protracted shock as fatal complication of treatment with D-penicillamine for rheumatoid arthritis in a child (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1980, Aug-08, Volume: 105, Issue:32

    Topics: Arthritis, Rheumatoid; Autopsy; Child; Drug Hypersensitivity; Female; Humans; Malpractice; Penicilla

1980
[Immunologic studies with the lymphocyte transformation test on the side effects of D-penicillamine therapy in Wilson's disease].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1980, Jul-01, Volume: 35, Issue:13

    Topics: Drug Hypersensitivity; Hepatolenticular Degeneration; Humans; Lymphocyte Activation; Penicillamine;

1980
Penicillamine hypersensitivity: successful desensitization of a patient with severe hepatic Wilson's disease.
    The American journal of gastroenterology, 1994, Volume: 89, Issue:3

    Topics: Adolescent; Drug Hypersensitivity; Female; Hepatolenticular Degeneration; Humans; Liver Transplantat

1994
Chromosome abnormalities in peripheral lymphocytes from patients with progressive systemic sclerosis.
    Rheumatology international, 1993, Volume: 12, Issue:6

    Topics: Adult; Aged; Asian People; Base Sequence; Cells, Cultured; Chromosome Aberrations; Chromosome Disord

1993
Suspected allergic reaction to penicillamine in mute swans.
    The Veterinary record, 1997, Apr-26, Volume: 140, Issue:17

    Topics: Animals; Birds; Drug Hypersensitivity; Penicillamine

1997
Suspected allergic reaction to penicillamine in mute swans.
    The Veterinary record, 1997, May-24, Volume: 140, Issue:21

    Topics: Animals; Antidotes; Birds; Dose-Response Relationship, Drug; Drug Hypersensitivity; Humans; Lead Poi

1997
T cell responses to D-penicillamine in drug-induced myasthenia gravis: recognition of modified DR1:peptide complexes.
    Journal of neuroimmunology, 1999, Jun-01, Volume: 97, Issue:1-2

    Topics: Aged; Amino Acid Sequence; Antirheumatic Agents; Autoimmune Diseases; Base Sequence; Blood Proteins;

1999
Contact reaction to penicillamine in vaginal secretions.
    Lancet (London, England), 1979, Jun-23, Volume: 1, Issue:8130

    Topics: Adult; Arthritis, Rheumatoid; Coitus; Drug Hypersensitivity; Female; Humans; Male; Menstruation; Pen

1979
Delayed hypersensitivity to tuberculin in rats: effects of antirheumatic drugs.
    Acta pharmacologica et toxicologica, 1979, Volume: 44, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Cyclophosphamide; Drug Evaluation, Preclinical; Drug Hypersensiti

1979
Antibody reactivity in penicillin-sensitive patients determinated with different penicillin derivatives.
    International archives of allergy and applied immunology, 1977, Volume: 54, Issue:1

    Topics: Adolescent; Adult; Aged; Ampicillin; Antibody Formation; Drug Hypersensitivity; Female; Humans; Immu

1977
The management of Wilson's disease with trienthylene tetramine 2HC1 (Trien 2HC1).
    Progress in clinical and biological research, 1979, Volume: 34

    Topics: Drug Hypersensitivity; Ethylenediamines; Female; Hepatolenticular Degeneration; Humans; Male; Penici

1979
[Monocytic neck lymphadenitis with morbileiform exanthema as side effect of penicillamine therapy of infantile Wilson's diseases].
    Kinderarztliche Praxis, 1978, Volume: 46, Issue:8

    Topics: Child; Drug Hypersensitivity; Exanthema; Female; Hepatolenticular Degeneration; Humans; Lymphadeniti

1978
[Penicillamine in the treatment of rheumatoid arthritis].
    Reumatologia, 1975, Volume: 13, Issue:2

    Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Evaluation; Drug Hypersensitivity; Humans; Middle Aged; Pen

1975
Editorial: Penicillamine: more lessons from experience.
    British medical journal, 1975, Jul-19, Volume: 3, Issue:5976

    Topics: Arthritis, Rheumatoid; Blood Cell Count; Drug Hypersensitivity; Humans; Penicillamine; Proteinuria;

1975
[Severe side-effects of treatment with D-penicillamine (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1975, Aug-08, Volume: 100, Issue:32

    Topics: Acute Disease; Adult; Arthritis, Rheumatoid; Drug Hypersensitivity; Female; Humans; Male; Middle Age

1975
A T-cell response to the anti-arthritic drug penicillamine in the mouse: requirements for generation of the drug-derived antigen.
    Immunology, 1992, Volume: 76, Issue:4

    Topics: Animals; Antigens; CD4-Positive T-Lymphocytes; Cell Division; Cells, Cultured; Drug Hypersensitivity

1992
Low back pain associated with penicillamine.
    BMJ (Clinical research ed.), 1991, Aug-31, Volume: 303, Issue:6801

    Topics: Aged; Arthritis, Rheumatoid; Back Pain; Drug Hypersensitivity; Female; Humans; Penicillamine

1991
[Long-term tolerability of tiopronin (Acadione) in the treatment of rheumatoid arthritis. Apropos of 140 personal cases].
    Revue du rhumatisme et des maladies osteo-articulaires, 1990, Volume: 57, Issue:2

    Topics: Arthritis, Rheumatoid; Drug Eruptions; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Mal

1990
[Antibodies against D-penicillamine in primary biliary cirrhosis].
    Immunitat und Infektion, 1990, Volume: 18, Issue:1

    Topics: Drug Hypersensitivity; Fluorescent Antibody Technique; Humans; Immunoglobulin G; Liver Cirrhosis, Bi

1990
[What clinical significance do antibodies to drugs have? Side effects are as possible as ineffectiveness].
    Fortschritte der Medizin, 1990, Jan-15, Volume: 108, Issue:1

    Topics: Animals; Antibodies; Drug Hypersensitivity; Humans; Immunoglobulin G; Penicillamine; Risk Factors

1990
Genetic control of delayed-type hypersensitivity to D-penicillamine antigen.
    International archives of allergy and applied immunology, 1988, Volume: 85, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Antigens; Drug Hypersensitivity; Epitopes; Hypersensitivity, Delaye

1988
[Trientin in Wilson's disease. Therapeutic possibilities in patients who cannot tolerate penicillamine].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1987, Aug-10, Volume: 107, Issue:22

    Topics: Adult; Drug Hypersensitivity; Ethylenediamines; Hepatolenticular Degeneration; Humans; Male; Penicil

1987
Oral zinc therapy normalizes serum uric acid level in Wilson's disease patients.
    The American journal of the medical sciences, 1986, Volume: 292, Issue:5

    Topics: Administration, Oral; Child; Drug Hypersensitivity; Female; Hepatolenticular Degeneration; Humans; L

1986
Adverse reactions of antirheumatic drugs.
    International journal of clinical pharmacology, therapy and toxicology, 1973, Volume: 7, Issue:2

    Topics: Analgesics; Anti-Inflammatory Agents; Chloroquine; Dimethylamines; Drug Hypersensitivity; Gold; Huma

1973
[Penicillamine therapy of chronic liver diseases].
    MMW, Munchener medizinische Wochenschrift, 1974, Feb-01, Volume: 116, Issue:5

    Topics: Azathioprine; Chronic Disease; Drug Hypersensitivity; Female; Glucocorticoids; Hepatitis; Humans; Li

1974
Immunological response to penicillamine in penicillin-allergic patients and in normal subjects.
    Postgraduate medical journal, 1974, Volume: 50 Suppl 2

    Topics: Antibody Formation; Drug Hypersensitivity; Humans; In Vitro Techniques; Lymphocyte Activation; Penic

1974
[Stomatitis caused by D-penicillamine].
    Revue de stomatologie et de chirurgie maxillo-faciale, 1973, Volume: 74, Issue:4

    Topics: Arthritis, Rheumatoid; Drug Hypersensitivity; Epidermolysis Bullosa; Female; Hepatolenticular Degene

1973
Diagnosis of allergic drug reaction.
    International archives of allergy and applied immunology, 1973, Volume: 45, Issue:1

    Topics: Antibodies, Antinuclear; Antibody Formation; Antigen-Antibody Complex; Coombs Test; Dextrans; Drug H

1973
[Mesenchyma-suppressing therapy of chronic aggressive hepatitis].
    Medizinische Klinik, 1972, Oct-06, Volume: 67, Issue:40

    Topics: Adolescent; Adult; Aged; Biopsy; Chronic Disease; Drug Hypersensitivity; Exanthema; Female; Gingival

1972
[Prevention and dissolution of cystine stones by D-penicillinamine].
    Harefuah, 1973, Jan-01, Volume: 84, Issue:1

    Topics: Adult; Cystinuria; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Kidney Calculi; Male; M

1973
[Gold therapy in chronic joint rheumatism].
    Der Internist, 1967, Volume: 8, Issue:7

    Topics: Acute Kidney Injury; Arthritis, Rheumatoid; Dimercaprol; Drug Hypersensitivity; Gold; Hematologic Di

1967
Two men with lead poisoning.
    The New Zealand medical journal, 1970, Volume: 71, Issue:456

    Topics: Adult; Chelating Agents; Dimercaprol; Drug Hypersensitivity; Edetic Acid; Humans; Lead; Lead Poisoni

1970
[Allergic-toxic liver damage due to D-penicillamine].
    Schweizerische medizinische Wochenschrift, 1972, Aug-26, Volume: 102, Issue:34

    Topics: Biopsy; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Female; Humans; Liver Functio

1972
Lupus-like syndrome induced by penicillamine in cystinuria.
    JAMA, 1972, Apr-24, Volume: 220, Issue:4

    Topics: Cystinuria; Drug Hypersensitivity; Female; Humans; Lupus Vulgaris; Middle Aged; Penicillamine

1972
Penicillamine for scleroderma.
    Archives of dermatology, 1968, Volume: 98, Issue:1

    Topics: Animals; Drug Hypersensitivity; Feeding and Eating Disorders; Humans; Joint Diseases; Leukopenia; Pe

1968
[Immunochemical mechanisms in penicillin allergies].
    Casopis lekaru ceskych, 1970, Volume: 109, Issue:6

    Topics: Animals; Antibodies, Anti-Idiotypic; Drug Hypersensitivity; Haptens; Humans; Hydrogen-Ion Concentrat

1970
[Penicillin allergy--penicillamine allergy. A successful desensitization of a penicillamine allergy with penicillin G in mobus Wilson].
    Munchener medizinische Wochenschrift (1950), 1970, Jul-17, Volume: 29

    Topics: Adolescent; Desensitization, Immunologic; Drug Hypersensitivity; Exanthema; Hepatolenticular Degener

1970
[Glossitis, stomatitis and onychopathy caused by penicillinamine].
    Bulletin de la Societe francaise de dermatologie et de syphiligraphie, 1968, Volume: 75, Issue:1

    Topics: Child; Drug Hypersensitivity; Female; Glossitis; Hepatolenticular Degeneration; Humans; Nails; Penic

1968
Focal glomerulitis due to penicillamine.
    Laboratory investigation; a journal of technical methods and pathology, 1968, Volume: 19, Issue:4

    Topics: Adult; Biopsy; Cystinuria; Drug Hypersensitivity; Female; Glomerulonephritis; Humans; Kidney Glomeru

1968
Toxicity of penicillamine.
    Postgraduate medical journal, 1968

    Topics: Adult; Drug Hypersensitivity; Female; Hepatolenticular Degeneration; Humans; Penicillamine

1968
Detection of antibodies in penicillamine sensitivity.
    Postgraduate medical journal, 1968

    Topics: Antibodies; Drug Hypersensitivity; Humans; Penicillamine

1968
Some complications observed in the treatment of cystinuria with D-penicillamine and N-acetyl-D-penicillamine.
    Postgraduate medical journal, 1968

    Topics: Adolescent; Adult; Child; Cystinuria; Drug Hypersensitivity; Female; Humans; Male; Penicillamine; Pr

1968
[Allergy to penicillin. Clinical study of 105 patients tested with penicilloyl-pollylysine].
    Revista brasileira de medicina, 1968, Volume: 25, Issue:9

    Topics: Allergens; Drug Hypersensitivity; Humans; Penicillamine; Penicillins

1968