Page last updated: 2024-11-07

penicillamine and Down Syndrome

penicillamine has been researched along with Down Syndrome in 3 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Woo, TY1
Rasmussen, JE1
Tu, JB1
Zellweger, H1
Gibson, SL1
Lam, CN1
McCrae, WM1
Goldberg, A1

Other Studies

3 other studies available for penicillamine and Down Syndrome

ArticleYear
Disorders of transepidermal elimination. Part 1.
    International journal of dermatology, 1985, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Cartilage Diseases; Child; Child, Preschool; Collagen Diseases; Down Syndro

1985
Blood-serotonin deficiency in Down's syndrome.
    Lancet (London, England), 1965, Oct-09, Volume: 2, Issue:7415

    Topics: Adolescent; Blood; Brain; Child; Down Syndrome; Humans; Penicillamine; Pyridoxine; Serotonin; Trypto

1965
Blood lead levels in normal and mentally deficiency children.
    Archives of disease in childhood, 1967, Volume: 42, Issue:226

    Topics: Brain Damage, Chronic; Child; Child, Preschool; Down Syndrome; Humans; Intellectual Disability; Lead

1967