penicillamine has been researched along with Diabetes Mellitus, Type 1 in 9 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe the association of balanitis xerotica obliterans and differentiated penile intraepithelial neoplasia (PeIN) with dermal elastosis and "bramble-bush" elastic fibers in a diabetic patient with no history of penicillamine intake." | 7.96 | Balanitis Xerotica Obliterans Associated With Differentiated Penile Intraepithelial Neoplasia and "Bramble-Bush" Elastic Fibers Accumulation: A Finding Not Specific for Penicillamine Intake. ( Navalon-Verdejo, P; Sabater-Abad, VJ; Sabater-Marco, V, 2020) |
| " Treatment with D-penicillamine was begun, and within five weeks anemia disappeared and the patient achieved complete resolution of symptoms." | 7.73 | [Weight loss, abdominal pain and anemia after a holiday abroad--case report of lead poisoning]. ( Kirchgatterer, A; Knoflach, P; Rammer, M, 2005) |
| " Conditions often associated with rheumatoid arthritis and also thought to have an immunologic basis, such as Sjögren's syndrome, Felty's syndrome, and rheumatoid vasculitis, and reactions to medications, such as gold and penicillamine, reveal an interesting spectrum of immunogenetic relationships." | 4.76 | Rheumatoid arthritis: relationship with HLA-D. ( Stastny, P, 1983) |
| "We describe the association of balanitis xerotica obliterans and differentiated penile intraepithelial neoplasia (PeIN) with dermal elastosis and "bramble-bush" elastic fibers in a diabetic patient with no history of penicillamine intake." | 3.96 | Balanitis Xerotica Obliterans Associated With Differentiated Penile Intraepithelial Neoplasia and "Bramble-Bush" Elastic Fibers Accumulation: A Finding Not Specific for Penicillamine Intake. ( Navalon-Verdejo, P; Sabater-Abad, VJ; Sabater-Marco, V, 2020) |
| " Treatment with D-penicillamine was begun, and within five weeks anemia disappeared and the patient achieved complete resolution of symptoms." | 3.73 | [Weight loss, abdominal pain and anemia after a holiday abroad--case report of lead poisoning]. ( Kirchgatterer, A; Knoflach, P; Rammer, M, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (22.22) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Sabater-Marco, V | 1 |
| Navalon-Verdejo, P | 1 |
| Sabater-Abad, VJ | 1 |
| Ahmad, S | 1 |
| Shahab, U | 1 |
| Habib, S | 1 |
| Salman Khan, M | 1 |
| Alam, K | 1 |
| Ali, A | 1 |
| Fehsel, K | 1 |
| Kolb-Bachofen, V | 1 |
| Kröncke, KD | 1 |
| Kirchgatterer, A | 1 |
| Rammer, M | 1 |
| Knoflach, P | 1 |
| Stastny, P | 1 |
| Kauschansky, A | 1 |
| Frydman, M | 1 |
| Assa, S | 1 |
| Kwon, OJ | 1 |
| Israel, S | 1 |
| Lazard, D | 1 |
| Sprecher, E | 1 |
| Bloch, K | 1 |
| Brautbar, C | 1 |
| Vardi, P | 1 |
| Jakus, V | 1 |
| Hrnciarová, M | 1 |
| Cársky, J | 1 |
| Krahulec, B | 1 |
| Rietbrock, N | 1 |
| Nakata, M | 1 |
| Uto, N | 1 |
| Maruyama, I | 1 |
| Yada, T | 1 |
| Schukowski, H | 1 |
| Lorenz, G | 1 |
| Haubenreiser, H | 1 |
| Lüdtke, E | 1 |
1 review available for penicillamine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Rheumatoid arthritis: relationship with HLA-D.
Topics: Adult; Arthritis, Juvenile; Arthritis, Rheumatoid; Child; Diabetes Mellitus, Type 1; Felty Syndrome; | 1983 |
1 trial available for penicillamine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Inhibition of nonenzymatic protein glycation and lipid peroxidation by drugs with antioxidant activity.
Topics: Aged; Antioxidants; Captopril; Depression, Chemical; Diabetes Mellitus, Type 1; Erythrocytes; Glycos | 1999 |
7 other studies available for penicillamine and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Balanitis Xerotica Obliterans Associated With Differentiated Penile Intraepithelial Neoplasia and "Bramble-Bush" Elastic Fibers Accumulation: A Finding Not Specific for Penicillamine Intake.
Topics: Aged, 80 and over; Balanitis Xerotica Obliterans; Carcinoma in Situ; Diabetes Mellitus, Type 1; Elas | 2020 |
Glycoxidative damage to human DNA: Neo-antigenic epitopes on DNA molecule could be a possible reason for autoimmune response in type 1 diabetes.
Topics: Autoimmunity; Deoxyguanosine; Diabetes Mellitus, Type 1; DNA; DNA Damage; Epitopes; Glycation End Pr | 2014 |
Necrosis is the predominant type of islet cell death during development of insulin-dependent diabetes mellitus in BB rats.
Topics: Animals; Annexin A5; Apoptosis; Blotting, Western; Cells, Cultured; Diabetes Mellitus, Experimental; | 2003 |
[Weight loss, abdominal pain and anemia after a holiday abroad--case report of lead poisoning].
Topics: Abdominal Pain; Anemia; Bone Marrow; Ceramics; Chelating Agents; Coronary Artery Disease; Diabetes M | 2005 |
D-penicillamine-induced pancreatic islet autoantibody production is independent of the immunogenetic background: a lesson from patients with Wilson's disease.
Topics: Adolescent; Adult; Autoantibodies; Child; Diabetes Mellitus, Type 1; Female; Haplotypes; Hepatolenti | 1998 |
Nitric oxide induces apoptosis via Ca2+-dependent processes in the pancreatic beta-cell line MIN6.
Topics: Animals; Apoptosis; Calcium; Cell Survival; Chelating Agents; Diabetes Mellitus, Type 1; Egtazic Aci | 1999 |
[Liver diseases in diabetic patients in childhood and adolescence].
Topics: Adolescent; Adult; Child; Child, Preschool; Chronic Disease; Diabetes Mellitus, Type 1; Fatty Liver; | 1976 |