Page last updated: 2024-11-07

penicillamine and Dermatosclerosis

penicillamine has been researched along with Dermatosclerosis in 47 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Research Excerpts

ExcerptRelevanceReference
"A 56-year-old woman with generalized morphea was treated with penicillamine."5.26Pemphigus in a patient treated with penicillamine for generalized morphea. ( Davies, MG; Holt, P, 1976)
"The spectrum of kidney involvement in systemic sclerosis (SSc) includes scleroderma renal crisis, widely recognized as the most severe renal-vascular complication, but also several forms of chronic renal vasculopathy and reduced renal function are complications of scleroderma."2.82Assessment of kidney involvement in systemic sclerosis: From scleroderma renal crisis to subclinical renal vasculopathy. ( Gigante, A; Leodori, G; Pellicano, C; Rosato, E; Villa, A, 2022)
"Although the aetiology of systemic sclerosis is unknown, its prevalence has been reported to be increased in workers exposed to silica."2.39[Systemic sclerosis]. ( Gustafsson, R, 1994)
"None of the patients with morphea had a history of thyroid pathology and the thyroid screenings were within normal limits."2.38[Scleroderma and thyroid diseases]. ( Claudy, A; Mourier-Clavreul, MC; Rousset, H, 1989)
"Primary biliary cirrhosis is a disease of the small bile ducts with altered immunologic responsiveness often associated with various collagen diseases."2.36Primary biliary cirrhosis as a collagen disease. ( Schaffner, F, 1979)
"Generalised morphea (GM) is a subtype of localised scleroderma that usually manifests with bilateral involvement."1.56Unilateral generalized morphea: First case report in Taiwan. ( Hsu, T; Lee, LW; Lu, MC; Shyur, SD, 2020)
"Localized scleroderma is a chronic inflammatory condition confined to the skin."1.39Localized scleroderma: a clinical study at a single center in Korea. ( Kim, J; Kim, JW; Noh, JW, 2013)
"Localized disease manifests as patches (morphea) or bandlike (linear scleroderma) areas of skin thickening."1.35Diagnosis and treatment of scleroderma. ( Adnan, ZA, 2008)
"Congenital localized scleroderma is a rare and probably underestimated condition in neonates."1.33Congenital localized scleroderma. ( Da Dalt, L; de Oliveira, SK; Eichenfield, LF; Galea, P; Mazur-Zielinska, H; Punaro, MG; Ros, J; Vallongo, C; Zulian, F, 2006)
"All children who were referred for fasciitis were included in the study."1.28The fasciitis-morphea complex in children. ( Miller, JJ, 1992)
"A 45-year-old woman had recurrent morphea lesions over 10 times in 6 years."1.28Palindromic morphea: multiple recurrence of morphea lesions in a case of systemic sclerosis. ( Mizutani, H; Mizutani, T; Okada, H; Shimizu, M; Tanaka, H, 1992)
"In all patients with diffuse systemic sclerosis there was objective improvement."1.28Penicillamine in systemic sclerosis: a reappraisal. ( Guindi, RT; Sattar, MA; Sugathan, TN, 1990)
"There is no accepted or proven treatment for localized scleroderma."1.28D-penicillamine in the treatment of localized scleroderma. ( Falanga, V; Medsger, TA, 1990)
"A 56-year-old woman with generalized morphea was treated with penicillamine."1.26Pemphigus in a patient treated with penicillamine for generalized morphea. ( Davies, MG; Holt, P, 1976)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199024 (51.06)18.7374
1990's13 (27.66)18.2507
2000's6 (12.77)29.6817
2010's1 (2.13)24.3611
2020's3 (6.38)2.80

Authors

AuthorsStudies
Gigante, A1
Leodori, G1
Pellicano, C1
Villa, A1
Rosato, E1
Atzori, L1
Ferreli, C1
Agosta, D1
Mou, M1
Coni, P1
Lachowicz, JI1
Pilloni, L1
Lu, MC1
Shyur, SD2
Lee, LW1
Hsu, T1
Noh, JW1
Kim, J1
Kim, JW1
Adnan, ZA1
Cox, D1
O' Regan, G1
Collins, S1
Byrne, A1
Irvine, A1
Watson, R1
Dourmishev, LA1
Stomonjakova, SR1
Dourmishev, AL1
Melani, L1
Caproni, M1
Cardinali, C1
Antiga, E1
Bernacchi, E1
Schincaglia, E1
Fabbri, P1
Zulian, F1
Vallongo, C1
de Oliveira, SK1
Punaro, MG1
Ros, J1
Mazur-Zielinska, H1
Galea, P1
Da Dalt, L1
Eichenfield, LF1
Coyle, HE1
Chapman, RS1
Bernstein, RM1
Hall, MA1
Gostelow, BE1
Crickx, B1
Belaich, S1
Kesler, RW1
McDonald, TD1
Balasubramaniam, M1
Saulsbury, FT1
Chan, WC1
Sy, LB1
Lin, YN1
Gustafsson, R1
Kaur, S1
Dhar, S1
Kanwar, AJ1
Farrington, ML1
Haas, JE1
Nazar-Stewart, V1
Mellins, ED1
Kato, Y1
Naito, Y1
Narita, Y1
Kuzuhara, S1
McGovern, TW1
Bennion, SD1
van Bergen, BH1
van Dooren-Greebe, RJ1
Fiselier, TJ1
Koopman, RJ1
Varga, J1
Ponor, I1
Tchebiner, JZ1
Davies, MG1
Holt, P1
Kornreich, HK1
King, KK1
Bernstein, BH1
Singsen, BH1
Hanson, V1
Schaffner, F1
Ansell, BM2
Davis, P1
Bleehen, SS1
Nasseh, GA1
Bywaters, EG1
Korting, GW1
Miller, JJ1
Mizutani, H1
Tanaka, H1
Okada, H1
Mizutani, T1
Shimizu, M1
Sattar, MA1
Guindi, RT1
Sugathan, TN1
Goldenstein-Schainberg, C1
Pereira, RM1
Gusukuma, MC1
Messina, WC1
Cossermelli, W1
Falanga, V1
Medsger, TA1
Liddle, BJ1
Mourier-Clavreul, MC1
Rousset, H1
Claudy, A1
Woo, TY1
Rasmussen, JE1
Asboe-Hansen, G1
Curley, RK1
Macfarlane, AW1
Evans, S1
Woodrow, JC1
Moynahan, EJ3
Herbert, CM1
Lindberg, KA1
Jayson, MI1
Bailey, AJ1
Elmes, ME1
Daróczy, J1
Gyöngyvér, S1
Kerl, H1
Klein, G1
Sandhofer, M1
Zimmermann, BK1
Balda, BR1

Reviews

6 reviews available for penicillamine and Dermatosclerosis

ArticleYear
Assessment of kidney involvement in systemic sclerosis: From scleroderma renal crisis to subclinical renal vasculopathy.
    The American journal of the medical sciences, 2022, Volume: 364, Issue:5

    Topics: Acute Kidney Injury; Antibodies, Antineutrophil Cytoplasmic; Humans; Kidney; Penicillamine; Peroxida

2022
[Systemic sclerosis].
    Nordisk medicin, 1994, Volume: 109, Issue:8-9

    Topics: Adjuvants, Immunologic; Adult; Female; Humans; Male; Middle Aged; Penicillamine; Scleroderma, Locali

1994
Clinical trials for the treatment of systemic sclerosis/scleroderma.
    Current rheumatology reports, 1999, Volume: 1, Issue:1

    Topics: Antirheumatic Agents; Clinical Trials as Topic; Cyclophosphamide; Female; Humans; Male; Penicillamin

1999
Primary biliary cirrhosis as a collagen disease.
    Postgraduate medicine, 1979, Volume: 65, Issue:6

    Topics: Adrenal Cortex Hormones; Antibodies; Antigen-Antibody Complex; Aspirin; Collagen Diseases; Complemen

1979
D-penicillamine in the treatment of rheumatoid arthritis and progressive systemic sclerosis.
    The British journal of dermatology, 1976, Volume: 94, Issue:6

    Topics: Animals; Arthritis, Rheumatoid; Chelating Agents; Collagen; Copper; Humans; Leukopenia; Nephrotic Sy

1976
[Scleroderma and thyroid diseases].
    Annales de dermatologie et de venereologie, 1989, Volume: 116, Issue:10

    Topics: Aged; Confidence Intervals; Female; Humans; Incidence; Male; Middle Aged; Penicillamine; Prospective

1989

Other Studies

41 other studies available for penicillamine and Dermatosclerosis

ArticleYear
Generalized scleroderma-like induration associated with D-penicillamine elastosis perforans serpiginosa in Wilson's disease.
    International journal of dermatology, 2023, Volume: 62, Issue:2

    Topics: Hepatolenticular Degeneration; Humans; Penicillamine; Scleroderma, Localized; Scleroderma, Systemic;

2023
Unilateral generalized morphea: First case report in Taiwan.
    Asian Pacific journal of allergy and immunology, 2020, Volume: 38, Issue:2

    Topics: Administration, Oral; Administration, Topical; Child; Emollients; Female; Humans; Hyperpigmentation;

2020
Localized scleroderma: a clinical study at a single center in Korea.
    International journal of rheumatic diseases, 2013, Volume: 16, Issue:4

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Antimalarials; Child; Colchicine; Female; Humans; Male;

2013
Diagnosis and treatment of scleroderma.
    Acta medica Indonesiana, 2008, Volume: 40, Issue:2

    Topics: Adrenal Cortex Hormones; Antirheumatic Agents; Female; Humans; Immunosuppressive Agents; Male; Penic

2008
Juvenile localised scleroderma: a retrospective review of response to systemic treatment.
    Irish journal of medical science, 2008, Volume: 177, Issue:4

    Topics: Adolescent; Adolescent Medicine; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antirheumatic Ag

2008
D-penicillamine induced polymyositis and morphea in a woman with Hashimoto thyroiditis.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2002, Volume: 16, Issue:5

    Topics: Aged; Antirheumatic Agents; Female; Humans; Penicillamine; Polymyositis; Scleroderma, Localized; Scl

2002
A case of nodular scleroderma.
    The Journal of dermatology, 2005, Volume: 32, Issue:12

    Topics: Adult; Biopsy, Needle; Combined Modality Therapy; Female; Follow-Up Studies; Humans; Immunohistochem

2005
Congenital localized scleroderma.
    The Journal of pediatrics, 2006, Volume: 149, Issue:2

    Topics: Atrophy; Biopsy; Chelating Agents; Child, Preschool; Female; Follow-Up Studies; Humans; Immunosuppre

2006
Eosinophilic fasciitis (Shulman syndrome) in association with morphoea and systemic sclerosis.
    Acta dermato-venereologica, 1980, Volume: 60, Issue:2

    Topics: Eosinophils; Fascia; Humans; Inflammation; Male; Middle Aged; Penicillamine; Scleroderma, Localized;

1980
Morphea-like reaction to D-penicillamine therapy.
    Annals of the rheumatic diseases, 1981, Volume: 40, Issue:1

    Topics: Adult; Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Penicillamine; Scleroderma, Localized;

1981
[Prognosis and treatment of scleroderma].
    Annales de medecine interne, 1984, Volume: 135, Issue:8

    Topics: Adrenal Cortex Hormones; Autoantibodies; Colchicine; Humans; Immunosuppressive Agents; Penicillamine

1984
Linear scleroderma in children.
    American journal of diseases of children (1960), 1981, Volume: 135, Issue:8

    Topics: Child; Female; Humans; Male; Penicillamine; Scleroderma, Localized

1981
Juvenile scleroderma: report of a case.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1995, Volume: 94, Issue:3

    Topics: Child; Drug Therapy, Combination; Humans; Male; Penicillamine; Prednisolone; Scleroderma, Localized;

1995
Treatment of childhood linear morphea with D-penicillamine.
    Pediatric dermatology, 1993, Volume: 10, Issue:2

    Topics: Child; Female; Humans; Penicillamine; Scleroderma, Localized; Treatment Failure

1993
Eosinophilic fasciitis in children frequently progresses to scleroderma-like cutaneous fibrosis.
    The Journal of rheumatology, 1993, Volume: 20, Issue:1

    Topics: Adolescent; Biopsy; Child; Child, Preschool; Eosinophilia; Fasciitis; Female; Fibrosis; Humans; Male

1993
D-penicillamine-induced myasthenia gravis in a case of eosinophilic fasciitis.
    Journal of the neurological sciences, 1997, Feb-27, Volume: 146, Issue:1

    Topics: Eosinophilia; Fasciitis; Female; Humans; Middle Aged; Myasthenia Gravis; Penicillamine; Scleroderma,

1997
Diffuse blisters and erosions in a patient with limited scleroderma. Penicillamine-induced pemphigus foliaceus (PIPF).
    Archives of dermatology, 1997, Volume: 133, Issue:4

    Topics: Aged; Blister; Drug Eruptions; Female; Humans; Pemphigus; Penicillamine; Scleroderma, Localized

1997
[D-penicillamine in treatment of scleroderma "en coup de sabre"].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1997, Volume: 48, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Follow-Up Studies; Forehead; Humans; Male; Penicillamine; Sclerode

1997
Breast enlargement induced by D-penicillamine.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:3

    Topics: Breast; Chelating Agents; Female; Humans; Middle Aged; Penicillamine; Scleroderma, Localized

2002
Pemphigus in a patient treated with penicillamine for generalized morphea.
    Archives of dermatology, 1976, Volume: 112, Issue:9

    Topics: Drug Eruptions; Female; Humans; Middle Aged; Pemphigus; Penicillamine; Scleroderma, Localized

1976
Scleroderma in childhood.
    Arthritis and rheumatism, 1977, Volume: 20, Issue:2 Suppl

    Topics: Adolescent; Central Nervous System Diseases; Child; Child, Preschool; Female; Humans; Immunosuppress

1977
[Treatment of scleroderma and dermatomyositis in childhood].
    La Clinica terapeutica, 1978, Jan-31, Volume: 84, Issue:2

    Topics: Adolescent; Age Factors; Aluminum Hydroxide; Anabolic Agents; Child; Cyclophosphamide; Dermatomyosit

1978
Scleroderma in childhood.
    Annals of the rheumatic diseases, 1976, Volume: 35, Issue:3

    Topics: Adolescent; Age Factors; Arthritis, Juvenile; Bone Diseases; Child; Chlorambucil; Diagnosis, Differe

1976
[Letter: Therapy of generalized circumscribed scleroderma].
    Die Medizinische Welt, 1975, Aug-08, Volume: 26, Issue:31-32

    Topics: Humans; Penicillamine; Progestins; Scleroderma, Localized

1975
The fasciitis-morphea complex in children.
    American journal of diseases of children (1960), 1992, Volume: 146, Issue:6

    Topics: Adolescent; Antibodies, Antinuclear; Biopsy; Blood Sedimentation; Child; Child, Preschool; Eosinophi

1992
Palindromic morphea: multiple recurrence of morphea lesions in a case of systemic sclerosis.
    The Journal of dermatology, 1992, Volume: 19, Issue:5

    Topics: Female; Humans; Middle Aged; Penicillamine; Prednisolone; Recurrence; Scleroderma, Localized; Sclero

1992
Penicillamine in systemic sclerosis: a reappraisal.
    Clinical rheumatology, 1990, Volume: 9, Issue:4

    Topics: Adult; Female; Humans; Male; Middle Aged; Penicillamine; Scleroderma, Localized; Scleroderma, System

1990
Childhood linear scleroderma "en coup de sabre" with uveitis.
    The Journal of pediatrics, 1990, Volume: 117, Issue:4

    Topics: Autoantibodies; Azathioprine; Child; Diagnosis, Differential; Facial Hemiatrophy; Humans; Male; Peni

1990
D-penicillamine in the treatment of localized scleroderma.
    Archives of dermatology, 1990, Volume: 126, Issue:5

    Topics: Dose-Response Relationship, Drug; Female; Humans; Male; Nephrotic Syndrome; Penicillamine; Proteinur

1990
Development of morphoea in rheumatoid arthritis treated with penicillamine.
    Annals of the rheumatic diseases, 1989, Volume: 48, Issue:11

    Topics: Aged; Arthritis, Rheumatoid; Female; Humans; Penicillamine; Scleroderma, Localized

1989
Disorders of transepidermal elimination. Part 1.
    International journal of dermatology, 1985, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Aged; Cartilage Diseases; Child; Child, Preschool; Collagen Diseases; Down Syndro

1985
Scleroderma.
    Journal of the American Academy of Dermatology, 1987, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Drug Therapy, Combination; Female; Glutamine; Hum

1987
The treatment of linear morphoea with D-penicillamine.
    Clinical and experimental dermatology, 1987, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Female; Humans; Male; Penicillamine; Scleroderma, Localized

1987
D(-)penicillamine in morphoea (localised scleroderma).
    Lancet (London, England), 1973, Feb-24, Volume: 1, Issue:7800

    Topics: Arthritis, Rheumatoid; Humans; Penicillamine; Scleroderma, Localized

1973
Biosynthesis and maturation of skin collagen in scleroderma, and effect of D-penicillamine.
    Lancet (London, England), 1974, Feb-09, Volume: 1, Issue:7850

    Topics: Adolescent; Adult; Age Factors; Aged; Amino Acids; Animals; Biopsy; Collagen; Culture Techniques; Fe

1974
Letter: Anti-inflammatory drugs and tissue copper.
    Lancet (London, England), 1974, Nov-30, Volume: 2, Issue:7892

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Copper; Humans; Liver Cirrhosis; Penicillamine; Pro

1974
Penicillamine in the treatment of morphoea and keloid in children.
    Postgraduate medical journal, 1974, Volume: 50 Suppl 2

    Topics: Child; Female; Humans; Keloid; Male; Penicillamine; Scleroderma, Localized

1974
[Investigations on the mode of action of D-penicillamine (Metalcaptase) in sclerodermia].
    Munchener medizinische Wochenschrift (1950), 1973, Aug-03, Volume: 115, Issue:31

    Topics: Adult; Birefringence; Child; Female; Humans; Male; Microscopy, Electron; Microscopy, Polarization; M

1973
[Treatment of "collagen and autoimmune" diseases (author's transl)].
    Wiener klinische Wochenschrift, 1973, Nov-23, Volume: 85, Issue:47

    Topics: Adolescent; Adult; Aminobenzoates; Azathioprine; Chloroquine; Cyclophosphamide; Dermatomyositis; Dex

1973
Morphoea (localized cutaneous scleroderma) treated with low-dosage penicillamine (4 cases, including coup de sabre).
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:11

    Topics: Child; Child, Preschool; Collagen; Female; Humans; Male; Penicillamine; Pyridoxine; Scleroderma, Loc

1973
[Studies on the solubility of skin collagen in scleroderma and the effect of D-penicillamine].
    Archiv fur dermatologische Forschung, 1972, Volume: 243, Issue:4

    Topics: Adult; Aged; Biopsy; Collagen; Female; Humans; Male; Middle Aged; Penicillamine; Scleroderma, Locali

1972