penicillamine has been researched along with Dermatitis Medicamentosa in 86 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral chelation therapy with d-penicillamine (d-PCN) has been proven to be effective in the treatment of mild-to-moderate lead poisoning." | 9.09 | Adverse effects of reduced-dose d-penicillamine in children with mild-to-moderate lead poisoning. ( Shannon, MW; Townsend, MK, 2000) |
| "After a controlled, double blind multicenter trial of D-penicillamine in the treatment of rheumatoid arthritis, 148 patients were followed for an additional year in an open label trial." | 9.06 | Toxicity of longterm low dose D-penicillamine therapy in rheumatoid arthritis. Cooperative Systematic Studies of Rheumatic Disease Group. ( , 1987) |
| " An open trial of SA 96 treatment (300 mg/day after meals for 16 weeks) was carried out in 11 patients with definite or classical rheumatoid arthritis and with therapeutic failure of previous gold salts and/or D-penicillamine therapy." | 9.06 | SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) in rheumatoid arthritis. ( Ishikawa, K; Sakaguchi, M, 1986) |
| "Six patients with primary biliary cirrhosis experienced lichen planus-like lesions while taking penicillamine." | 9.05 | Lichen planus-like lesions caused by penicillamine in primary biliary cirrhosis. ( Dickson, ER; Fleming, CR; Rogers, RS; Seehafer, JR, 1981) |
| "Forty-six patients with rheumatoid arthritis, 22 receiving D-penicillamine and 2j alclofenac, took part in a 6-month single-bind external observer trial to compare the efficacy and toxicity of these drugs in the treatment of severe rheumatoid arthritis." | 9.04 | Alclofenac and D-penicillamine. Comparative trial in rheumatoid arthritis. ( Berry, H; Evans, SJ; Fernandes, L; Ford-Hutchinson, AW; Hamilton, EB, 1978) |
| "In the present study, the side effects of d-Penicillamine therapy in 54 patients with rheumatoid arthritis are analyzed." | 8.77 | [Side effects of d-penicillamine in the treatment of rheumatoid arthritis]. ( Bianchini, D; Cataldo, R; Damiani, D; Florean, M; Mazzanti, G; Mesesnel, E; Paladini, G, 1986) |
| "The use of penicillamine in rheumatoid arthritis (RA) is limited by the incidence of adverse effects, some of which are potentially hazardous." | 8.76 | Penicillamine in rheumatoid arthritis: adverse effects. ( Hill, HF, 1979) |
| "A case of pemphigus foliaceus arising during the administration of D-penicillamine was reported." | 7.73 | Decline of anti-desmoglein 1 IgG ELISA scores by withdrawal of D-penicillamine in drug-induced pemphigus foliaceus. ( Amagai, M; Nagao, K; Tanikawa, A; Yamamoto, N, 2005) |
| "We report the case of an 80-year-old woman who developed pemphigus foliaceus while taking penicillamine for rheumatoid arthritis." | 7.68 | [Pemphigus foliaceus caused by penicillamine]. ( Burg, G; Burger, M; Hartmann, AA; Zentner, A; Zillikens, D, 1993) |
| "After considering the cutaneous side effects of D-penicillamine in rheumatoid arthritis management, a few cases of cutaneous adverse reaction observed in 5 (13%) of 38 patients, who received the drugs, are described." | 7.68 | [Cutaneous side effects induced by D-penicillamine in the treatment of rheumatoid arthritis]. ( Baratelli, E; Broggini, M; Cappelli, A; Crespi, E; Filardi, PG; Volontè, S, 1990) |
| "Sixty-two consecutive patients, with rheumatoid arthritis (RA) who received D-penicillamine were studied retrospectively to identify predictive risk factors for D-penicillamine toxicity." | 7.68 | D-penicillamine toxicity in Greek patients with rheumatoid arthritis: anti-Ro(SSA) antibodies and cryoglobulinemia are predictive factors. ( Drosos, AA; Moutsopoulos, HM; Skopouli, FN; Vlachoyiannopoulos, PG; Zerva, LV, 1991) |
| " proteinuria, haematological abnormalities, stomatitis, diarrhoea and dermatitis) in rheumatoid arthritis (RA) to sodium aurothiomalate (gold) and to D-penicillamine (PA) were studied in 32 patients." | 7.67 | HLA antigens and adverse drug reactions to sodium aurothiomalate and D-penicillamine in patients with rheumatoid arthritis. ( Bjelle, A; Dahlqvist, SR; Möller, E; Ström, H, 1985) |
| "A 57-year-old patient with rheumatoid arthritis, who was being treated with D-penicillamine, developed a bullous eruption 2 months after the onset of treatment." | 7.67 | [Pemphigus herpetiformis following D-penicillamine in a patient with HLA B8]. ( David, M; Ingber, A; Sandbank, M; Weltfriend, S, 1988) |
| "The long term efficacy and tolerability of sulphasalazine (SASP) in the treatment of 21 patients with active classical or definite rheumatoid arthritis (RA) were examined and compared with the effects of penicillamine in a similarly active group of RA patients." | 7.67 | The long term effects of sulphasalazine in the treatment of rheumatoid arthritis and a comparative study with penicillamine. ( Bacon, PA; Crockson, AP; Farr, M; Tunn, E, 1984) |
| "A case of a severe, widespread bullous dermatosis clinically resembling pemphigus foliaceus occurred during treatment with penicillamine hydrochloride in a patient with rheumatoid arthritis." | 7.67 | Penicillamine-induced pemphigus foliaceus-like dermatosis. A case with unusual features, successfully treated by plasmapheresis. ( Bahmer, FA; Bambauer, R; Stenger, D, 1985) |
| "Ninety patients with rheumatoid arthritis who had received courses of gold followed by penicillamine for their disease were evaluated to determine the predictiveness of a certain response or adverse reaction to gold for the same response or adverse reaction to penicillamine." | 7.66 | Sequential gold and penicillamine therapy in rheumatoid arthritis. ( Cassady, J; Halla, JT; Hardin, JG, 1982) |
| "2 women, 62 and 69 years old, both suffering from rheumatoid arthritis, were treated for 1 and 1 1/2 years, respectively, with penicillamine." | 7.66 | Two cases of penicillamine-induced pemphigus erythematosus. ( Thorvaldsen, J, 1979) |
| "Skin rashes, proteinuria, systemic lupus erythematosus, polymyositis and myasthenia gravis have all been recorded as complications of penicillamine therapy in patients with rheumatoid arthritis." | 7.66 | Multiple side effects of penicillamine therapy in one patient with rheumatoid arthritis. ( Essigman, WK, 1982) |
| "A 44-year-old woman with rheumatoid arthritis and vasculitis of the skin developed a lupus erythematosus-like reaction after 5 weeks of D-penicillamine therapy." | 7.66 | Penicillamine-induced lupus-like reaction in rheumatoid arthritis and vasculitis. ( Thorvaldsen, J, 1981) |
| "A 2 1/4 year-old boy was treated for cystinuria and urolithiasis with high fluid intake, sodium bicarbonate, and D-penicillamine, over a period of 5 3/4 years, unauthorized interruptions and prescribed pauses included." | 7.66 | Skin and bone lesions (dermato-osteolathyrism), possible side effects of D-penicillamine treatment, in a boy with cystinuria. ( Gitzelmann, R; Otten, A; Steinmann, B, 1979) |
| "One hundred fourteen patients with definite or classic rheumatoid arthritis were followed prospectively between January 1976 and April 1981 to monitor their toxicity pattern to D-penicillamine." | 7.66 | Prior gold therapy does not influence the adverse effects of D-penicillamine in rheumatoid arthritis. ( Buchanan, WW; Howard-Lock, HE; Kean, WF; Lock, CJ, 1982) |
| " Our patient is one of three siblings on Penicillamine, she was the only one who developed massive breast enlargement four months after commencing Penicillamine therapy, as well as dermatological adverse reactions and myasthenia gravis three more months later." | 5.38 | Concurrent massive breast enlargement, myasthenia gravis and dermopathy as manifestations of penicillamine toxicity in a Wilson's disease patient. ( Latif, SA; Poh, WY; Tan, SS, 2012) |
| "A 56-year-old woman with generalized morphea was treated with penicillamine." | 5.26 | Pemphigus in a patient treated with penicillamine for generalized morphea. ( Davies, MG; Holt, P, 1976) |
| "Oral chelation therapy with d-penicillamine (d-PCN) has been proven to be effective in the treatment of mild-to-moderate lead poisoning." | 5.09 | Adverse effects of reduced-dose d-penicillamine in children with mild-to-moderate lead poisoning. ( Shannon, MW; Townsend, MK, 2000) |
| " An open trial of SA 96 treatment (300 mg/day after meals for 16 weeks) was carried out in 11 patients with definite or classical rheumatoid arthritis and with therapeutic failure of previous gold salts and/or D-penicillamine therapy." | 5.06 | SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) in rheumatoid arthritis. ( Ishikawa, K; Sakaguchi, M, 1986) |
| "After a controlled, double blind multicenter trial of D-penicillamine in the treatment of rheumatoid arthritis, 148 patients were followed for an additional year in an open label trial." | 5.06 | Toxicity of longterm low dose D-penicillamine therapy in rheumatoid arthritis. Cooperative Systematic Studies of Rheumatic Disease Group. ( , 1987) |
| "Six patients with primary biliary cirrhosis experienced lichen planus-like lesions while taking penicillamine." | 5.05 | Lichen planus-like lesions caused by penicillamine in primary biliary cirrhosis. ( Dickson, ER; Fleming, CR; Rogers, RS; Seehafer, JR, 1981) |
| "Forty-six patients with rheumatoid arthritis, 22 receiving D-penicillamine and 2j alclofenac, took part in a 6-month single-bind external observer trial to compare the efficacy and toxicity of these drugs in the treatment of severe rheumatoid arthritis." | 5.04 | Alclofenac and D-penicillamine. Comparative trial in rheumatoid arthritis. ( Berry, H; Evans, SJ; Fernandes, L; Ford-Hutchinson, AW; Hamilton, EB, 1978) |
| " A 20-year-old man with hepatolenticular degeneration, under prolonged treatment with D-penicillamine, presented with a circular or serpiginous arrangement of nuchal papules." | 4.79 | Penicillamine-induced degenerative dermatoses: report of a case and brief review of such dermatoses. ( Iozumi, K; Nakagawa, H; Tamaki, K, 1997) |
| "In the present study, the side effects of d-Penicillamine therapy in 54 patients with rheumatoid arthritis are analyzed." | 4.77 | [Side effects of d-penicillamine in the treatment of rheumatoid arthritis]. ( Bianchini, D; Cataldo, R; Damiani, D; Florean, M; Mazzanti, G; Mesesnel, E; Paladini, G, 1986) |
| "The use of penicillamine in rheumatoid arthritis (RA) is limited by the incidence of adverse effects, some of which are potentially hazardous." | 4.76 | Penicillamine in rheumatoid arthritis: adverse effects. ( Hill, HF, 1979) |
| "A case of pemphigus foliaceus arising during the administration of D-penicillamine was reported." | 3.73 | Decline of anti-desmoglein 1 IgG ELISA scores by withdrawal of D-penicillamine in drug-induced pemphigus foliaceus. ( Amagai, M; Nagao, K; Tanikawa, A; Yamamoto, N, 2005) |
| " We tested this hypothesis in an animal model in which penicillamine causes an autoimmune syndrome in Brown Norway rats." | 3.71 | Factors that modify penicillamine-induced autoimmunity in Brown Norway rats: failure of the Th1/Th2 paradigm. ( Sayeh, E; Uetrecht, JP, 2001) |
| "Sixty-two consecutive patients, with rheumatoid arthritis (RA) who received D-penicillamine were studied retrospectively to identify predictive risk factors for D-penicillamine toxicity." | 3.68 | D-penicillamine toxicity in Greek patients with rheumatoid arthritis: anti-Ro(SSA) antibodies and cryoglobulinemia are predictive factors. ( Drosos, AA; Moutsopoulos, HM; Skopouli, FN; Vlachoyiannopoulos, PG; Zerva, LV, 1991) |
| "We report the case of an 80-year-old woman who developed pemphigus foliaceus while taking penicillamine for rheumatoid arthritis." | 3.68 | [Pemphigus foliaceus caused by penicillamine]. ( Burg, G; Burger, M; Hartmann, AA; Zentner, A; Zillikens, D, 1993) |
| "After considering the cutaneous side effects of D-penicillamine in rheumatoid arthritis management, a few cases of cutaneous adverse reaction observed in 5 (13%) of 38 patients, who received the drugs, are described." | 3.68 | [Cutaneous side effects induced by D-penicillamine in the treatment of rheumatoid arthritis]. ( Baratelli, E; Broggini, M; Cappelli, A; Crespi, E; Filardi, PG; Volontè, S, 1990) |
| "The long term efficacy and tolerability of sulphasalazine (SASP) in the treatment of 21 patients with active classical or definite rheumatoid arthritis (RA) were examined and compared with the effects of penicillamine in a similarly active group of RA patients." | 3.67 | The long term effects of sulphasalazine in the treatment of rheumatoid arthritis and a comparative study with penicillamine. ( Bacon, PA; Crockson, AP; Farr, M; Tunn, E, 1984) |
| "A 57-year-old patient with rheumatoid arthritis, who was being treated with D-penicillamine, developed a bullous eruption 2 months after the onset of treatment." | 3.67 | [Pemphigus herpetiformis following D-penicillamine in a patient with HLA B8]. ( David, M; Ingber, A; Sandbank, M; Weltfriend, S, 1988) |
| " proteinuria, haematological abnormalities, stomatitis, diarrhoea and dermatitis) in rheumatoid arthritis (RA) to sodium aurothiomalate (gold) and to D-penicillamine (PA) were studied in 32 patients." | 3.67 | HLA antigens and adverse drug reactions to sodium aurothiomalate and D-penicillamine in patients with rheumatoid arthritis. ( Bjelle, A; Dahlqvist, SR; Möller, E; Ström, H, 1985) |
| "A case of a severe, widespread bullous dermatosis clinically resembling pemphigus foliaceus occurred during treatment with penicillamine hydrochloride in a patient with rheumatoid arthritis." | 3.67 | Penicillamine-induced pemphigus foliaceus-like dermatosis. A case with unusual features, successfully treated by plasmapheresis. ( Bahmer, FA; Bambauer, R; Stenger, D, 1985) |
| "Ninety patients with rheumatoid arthritis who had received courses of gold followed by penicillamine for their disease were evaluated to determine the predictiveness of a certain response or adverse reaction to gold for the same response or adverse reaction to penicillamine." | 3.66 | Sequential gold and penicillamine therapy in rheumatoid arthritis. ( Cassady, J; Halla, JT; Hardin, JG, 1982) |
| "One hundred fourteen patients with definite or classic rheumatoid arthritis were followed prospectively between January 1976 and April 1981 to monitor their toxicity pattern to D-penicillamine." | 3.66 | Prior gold therapy does not influence the adverse effects of D-penicillamine in rheumatoid arthritis. ( Buchanan, WW; Howard-Lock, HE; Kean, WF; Lock, CJ, 1982) |
| "Skin rashes, proteinuria, systemic lupus erythematosus, polymyositis and myasthenia gravis have all been recorded as complications of penicillamine therapy in patients with rheumatoid arthritis." | 3.66 | Multiple side effects of penicillamine therapy in one patient with rheumatoid arthritis. ( Essigman, WK, 1982) |
| "2 women, 62 and 69 years old, both suffering from rheumatoid arthritis, were treated for 1 and 1 1/2 years, respectively, with penicillamine." | 3.66 | Two cases of penicillamine-induced pemphigus erythematosus. ( Thorvaldsen, J, 1979) |
| "A 2 1/4 year-old boy was treated for cystinuria and urolithiasis with high fluid intake, sodium bicarbonate, and D-penicillamine, over a period of 5 3/4 years, unauthorized interruptions and prescribed pauses included." | 3.66 | Skin and bone lesions (dermato-osteolathyrism), possible side effects of D-penicillamine treatment, in a boy with cystinuria. ( Gitzelmann, R; Otten, A; Steinmann, B, 1979) |
| "A 44-year-old woman with rheumatoid arthritis and vasculitis of the skin developed a lupus erythematosus-like reaction after 5 weeks of D-penicillamine therapy." | 3.66 | Penicillamine-induced lupus-like reaction in rheumatoid arthritis and vasculitis. ( Thorvaldsen, J, 1981) |
| "Although treatment has been well defined for childhood lead poisoning and for industrial lead exposure, the treatment of lead nephropathy has been poorly studied." | 3.65 | Chelation therapy in lead nephropathy. ( Morgan, JM, 1975) |
| "Many of the adverse reactions produced by penicillamine and other compounds with an active sulfhydryl group form a distinctive pattern when viewed as a class." | 2.37 | Adverse effects profile of sulfhydryl compounds in man. ( Jaffe, IA, 1986) |
| " The types of cutaneous manifestations may, in some instances, be correlated with the disease being treated and the dosage and duration of penicillamine therapy." | 2.36 | Penicillamine: review and cutaneous manifestations. ( Alter, JN; Fisher, M; Levy, RS, 1983) |
| " Our patient is one of three siblings on Penicillamine, she was the only one who developed massive breast enlargement four months after commencing Penicillamine therapy, as well as dermatological adverse reactions and myasthenia gravis three more months later." | 1.38 | Concurrent massive breast enlargement, myasthenia gravis and dermopathy as manifestations of penicillamine toxicity in a Wilson's disease patient. ( Latif, SA; Poh, WY; Tan, SS, 2012) |
| "A 58-year-old woman with progressive systemic sclerosis developed a butterfly erythematous eruption, hemorrhagic maculae, crusting, and erosions on the face 15 days following administration of D-penicillamine." | 1.28 | Lupus erythematosus-like eruption due to D-penicillamine in progressive systemic sclerosis. ( Lazarova, AZ; Obreshkova, EV; Tsankov, NK; Vasileva, SG, 1990) |
| " Adverse effects occurred more frequently after rapid increases in dosage." | 1.27 | The toxicity of D-penicillamine in systemic sclerosis. ( Blair, S; Medsger, TA; Steen, VD, 1986) |
| "The majority of patients were being treated for rheumatoid arthritis." | 1.27 | European League against Rheumatism study of adverse reactions to D-penicillamine. ( Kay, A, 1986) |
| "A 56-year-old woman with generalized morphea was treated with penicillamine." | 1.26 | Pemphigus in a patient treated with penicillamine for generalized morphea. ( Davies, MG; Holt, P, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (73.26) | 18.7374 |
| 1990's | 12 (13.95) | 18.2507 |
| 2000's | 8 (9.30) | 29.6817 |
| 2010's | 3 (3.49) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ingen-Housz-Oro, S | 2 |
| Grootenboer-Mignot, S | 1 |
| Ortonne, N | 1 |
| Nahon, S | 1 |
| Horvath, J | 1 |
| Bernardeschi, C | 1 |
| Laffitte, E | 1 |
| André, C | 1 |
| Chollet-Martin, S | 1 |
| Wolkenstein, P | 1 |
| Chosidow, O | 1 |
| Bain, S | 1 |
| Eligar, VS | 1 |
| Tan, SS | 1 |
| Latif, SA | 1 |
| Poh, WY | 1 |
| STERNLIEB, I | 1 |
| SCHEINBERG, IH | 1 |
| Nagao, K | 1 |
| Tanikawa, A | 1 |
| Yamamoto, N | 1 |
| Amagai, M | 1 |
| Choi, HJ | 1 |
| Lee, DK | 1 |
| Chang, SE | 1 |
| Lee, MW | 1 |
| Choi, JH | 1 |
| Moon, KC | 1 |
| Koh, JK | 1 |
| Davis, DM | 1 |
| Otley, CC | 1 |
| Witman, PM | 1 |
| Rayatt, S | 1 |
| Pandey, U | 1 |
| Khanna, A | 1 |
| Devillière, M | 1 |
| Weber, N | 1 |
| Cordoliani, F | 1 |
| Vignon-Pennamen, MD | 1 |
| Manciet, JR | 1 |
| Sigal-Grinberg, M | 1 |
| Touraine, R | 1 |
| Revuz, J | 1 |
| Dubertret, L | 1 |
| de Prost, Y | 1 |
| Guillaume, JC | 1 |
| Farr, M | 1 |
| Tunn, E | 1 |
| Crockson, AP | 1 |
| Bacon, PA | 1 |
| Halla, JT | 1 |
| Cassady, J | 1 |
| Hardin, JG | 1 |
| Egeland, T | 1 |
| Brandtzaeg, P | 1 |
| Kean, WF | 3 |
| Lock, CJ | 2 |
| Howard-Lock, HE | 2 |
| Buchanan, WW | 1 |
| Bailin, PL | 1 |
| Matkaluk, RM | 1 |
| Essigman, WK | 1 |
| Levy, RS | 1 |
| Fisher, M | 1 |
| Alter, JN | 1 |
| Chan, HL | 1 |
| Thomas, MH | 1 |
| Rothermich, NO | 1 |
| Philips, VK | 1 |
| Bergen, W | 1 |
| Hedrick, SW | 1 |
| Venencie, PY | 1 |
| Morel, P | 1 |
| Bernstein, RM | 1 |
| Hall, MA | 1 |
| Gostelow, BE | 1 |
| Seehafer, JR | 1 |
| Rogers, RS | 1 |
| Fleming, CR | 1 |
| Dickson, ER | 1 |
| Hashimoto, K | 1 |
| McEvoy, B | 1 |
| Belcher, R | 1 |
| Trunnell, TN | 1 |
| Adelman, HM | 1 |
| Waisman, M | 1 |
| Thorvaldsen, J | 2 |
| Agababova, E | 1 |
| Sidel'nikova, S | 1 |
| Aseeva, E | 1 |
| Nikol'skaia, N | 1 |
| Gaziian, R | 1 |
| Krel', AA | 2 |
| Kanevskaia, MZ | 1 |
| Rashchupkina, ZP | 1 |
| Bolotin, EV | 1 |
| Chichasova, NV | 1 |
| Shaw, M | 1 |
| Jarrett, A | 1 |
| Anastassiades, TP | 1 |
| Dwosh, IL | 1 |
| Ford, PM | 1 |
| Kelly, WG | 1 |
| Dok, CM | 1 |
| Wilhelm, KP | 1 |
| Wolff, HH | 1 |
| De Moor, A | 1 |
| Van Hecke, E | 1 |
| Kestelyn, P | 1 |
| Zillikens, D | 1 |
| Zentner, A | 1 |
| Burger, M | 1 |
| Hartmann, AA | 1 |
| Burg, G | 1 |
| Bialy-Golan, A | 1 |
| Brenner, S | 1 |
| McGovern, TW | 1 |
| Bennion, SD | 1 |
| Iozumi, K | 1 |
| Nakagawa, H | 1 |
| Tamaki, K | 1 |
| Tóth, GG | 1 |
| Jonkman, MF | 1 |
| Shannon, MW | 1 |
| Townsend, MK | 1 |
| Sayeh, E | 1 |
| Uetrecht, JP | 1 |
| Poon, E | 1 |
| Mason, GH | 1 |
| Oh, C | 1 |
| Berry, H | 1 |
| Fernandes, L | 1 |
| Ford-Hutchinson, AW | 1 |
| Evans, SJ | 1 |
| Hamilton, EB | 1 |
| Steigleder, GK | 1 |
| Morgan, JM | 1 |
| Tan, SG | 1 |
| Rowell, NR | 1 |
| Davies, MG | 1 |
| Holt, P | 1 |
| Ivanova, TS | 1 |
| Perl, S | 1 |
| Hauftová, D | 1 |
| Kennedy, C | 1 |
| Hodge, L | 1 |
| Sanderson, KV | 1 |
| Christoph, R | 1 |
| Genth, E | 1 |
| Grussendorf, EI | 1 |
| Hartl, PW | 1 |
| Colombo, B | 1 |
| Gerloni, V | 1 |
| Hill, HF | 1 |
| Steinmann, B | 1 |
| Otten, A | 1 |
| Gitzelmann, R | 1 |
| Vlachoyiannopoulos, PG | 1 |
| Zerva, LV | 1 |
| Skopouli, FN | 1 |
| Drosos, AA | 1 |
| Moutsopoulos, HM | 1 |
| Broggini, M | 1 |
| Baratelli, E | 1 |
| Cappelli, A | 1 |
| Crespi, E | 1 |
| Filardi, PG | 1 |
| Volontè, S | 1 |
| Sany, J | 1 |
| Combe, B | 1 |
| Verdie-Petibon, D | 1 |
| Tagemouati, A | 1 |
| Daures, JP | 1 |
| Tsankov, NK | 1 |
| Lazarova, AZ | 1 |
| Vasileva, SG | 1 |
| Obreshkova, EV | 1 |
| Coenraads, PJ | 1 |
| Woest, TE | 1 |
| Blanksma, LJ | 1 |
| Houtman, WA | 1 |
| Civatte, J | 2 |
| Sahn, EE | 1 |
| Maize, JC | 1 |
| Garen, PD | 1 |
| Mullins, SC | 1 |
| Silver, RM | 1 |
| Kohn, SR | 1 |
| Jaffe, IA | 1 |
| Ishikawa, K | 1 |
| Sakaguchi, M | 1 |
| Steen, VD | 1 |
| Blair, S | 1 |
| Medsger, TA | 1 |
| Kay, A | 1 |
| Mewa, A | 1 |
| Mazzanti, G | 1 |
| Paladini, G | 1 |
| Damiani, D | 1 |
| Bianchini, D | 1 |
| Florean, M | 1 |
| Mesesnel, E | 1 |
| Cataldo, R | 1 |
| Brown, MD | 1 |
| Dubin, HV | 1 |
| Magnus, JH | 1 |
| Gran, JT | 1 |
| Mikkelsen, K | 1 |
| Nygaard, H | 1 |
| Brath, HK | 1 |
| van Joost, T | 1 |
| de Leeuw, J | 1 |
| Weltfriend, S | 1 |
| Ingber, A | 1 |
| David, M | 1 |
| Sandbank, M | 1 |
| Dahlqvist, SR | 1 |
| Ström, H | 1 |
| Bjelle, A | 1 |
| Möller, E | 1 |
| Bahmer, FA | 1 |
| Bambauer, R | 1 |
| Stenger, D | 1 |
| Batlle Gualda, E | 1 |
| Katz, R | 1 |
| Werner, T | 1 |
| Weinmann, HM | 1 |
| Davis, CM | 1 |
| Christeler, A | 1 |
| Delacrétaz, J | 1 |
| Mirouze, J | 2 |
| Jaffiol, C | 1 |
| Mary, P | 2 |
| Harpey, JP | 1 |
| Moulias, R | 1 |
| Goust, JM | 1 |
| Berthaux, P | 1 |
| Strickland, GT | 1 |
| Rimbaud, P | 1 |
| Meynadier, J | 1 |
| Belaich, S | 1 |
| Blanchet, P | 1 |
15 reviews available for penicillamine and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Cutaneous reactions to rheumatological drugs.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Azathioprine; Cushing Syndrome; Cy | 1982 |
Penicillamine: review and cutaneous manifestations.
Topics: Autoimmune Diseases; Collagen; Dermatitis, Atopic; Drug Eruptions; Elastin; Humans; Lichen Planus; P | 1983 |
Penicillamine-induced bullous dermatoses.
Topics: Drug Eruptions; Humans; Penicillamine; Skin Diseases, Vesiculobullous | 1996 |
Penicillamine-induced degenerative dermatoses: report of a case and brief review of such dermatoses.
Topics: Adult; Chelating Agents; Collagen; Drug Eruptions; Elastic Tissue; Hepatolenticular Degeneration; Hu | 1997 |
[Clinical use of d-penicillamine, complications and possibilities of their prevention].
Topics: Collagen Diseases; Dose-Response Relationship, Drug; Drug Eruptions; Drug Evaluation; Drug Hypersens | 1977 |
[Penicillamine: its use in rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Eruptions; Drug Evaluation; Female; Fever; Gastrointestinal | 1979 |
Penicillamine in rheumatoid arthritis: adverse effects.
Topics: Anemia, Aplastic; Anti-Glomerular Basement Membrane Disease; Arthritis, Rheumatoid; Bone Marrow; Dru | 1979 |
[Drug-induced pemphigus diseases].
Topics: Drug Eruptions; Humans; Pemphigus; Penicillamine; Pyrithioxin | 1989 |
D-penicillamine-induced elastosis perforans serpiginosa in a child with juvenile rheumatoid arthritis. Report of a case and review of the literature.
Topics: Arthritis, Juvenile; Child; Drug Eruptions; Elastic Tissue; Female; Humans; Microscopy, Electron; Pe | 1989 |
Adverse effects profile of sulfhydryl compounds in man.
Topics: Anemia, Aplastic; Autoimmune Diseases; Captopril; Drug Eruptions; Glomerulonephritis; Humans; Neutro | 1986 |
D-penicillamine: chemistry and clinical use in rheumatic disease.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Drug Eruptions; Gold Sodium Thiomalate; Hematologic Dise | 1986 |
[Side effects of d-penicillamine in the treatment of rheumatoid arthritis].
Topics: Adult; Aged; Arthritis, Rheumatoid; Autoimmune Diseases; Drug Eruptions; Female; Hematologic Disease | 1986 |
[Auranofin and aurothiomalate sodium: a comparative review (and II) Efficacy, tolerance and safety].
Topics: Anemia; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Clinical Trials as Topic; Diarrhea; Drug | 1985 |
[10 years of penicillamine].
Topics: Cystinuria; Drug Eruptions; Gold; Hepatolenticular Degeneration; Humans; Lead Poisoning; Leukopenia; | 1966 |
[Dermatology from 1969 to 1973].
Topics: Agammaglobulinemia; Blood Protein Disorders; Bromides; Candidiasis, Cutaneous; Carcinoid Tumor; Derm | 1974 |
8 trials available for penicillamine and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Gold vs D-penicillamine double blind study and followup.
Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug Eruptions; Female; | 1984 |
Lichen planus-like lesions caused by penicillamine in primary biliary cirrhosis.
Topics: Clinical Trials as Topic; Double-Blind Method; Drug Eruptions; Female; Humans; Lichen Planus; Liver | 1981 |
[Comparative study of the efficacy of 2 different doses of D-penicillamine in rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug Eruptions; Female; Humans | 1981 |
Adverse effects of reduced-dose d-penicillamine in children with mild-to-moderate lead poisoning.
Topics: Adolescent; Blood Cell Count; Chelating Agents; Child; Child, Preschool; Drug Eruptions; Female; Hum | 2000 |
Alclofenac and D-penicillamine. Comparative trial in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Eruptions; Female; Humans; Male; Middle Aged; | 1978 |
SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury | 1986 |
Toxicity of longterm low dose D-penicillamine therapy in rheumatoid arthritis. Cooperative Systematic Studies of Rheumatic Disease Group.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Drug | 1987 |
[Auranofin and aurothiomalate sodium: a comparative review (and II) Efficacy, tolerance and safety].
Topics: Anemia; Arthritis, Rheumatoid; Auranofin; Aurothioglucose; Clinical Trials as Topic; Diarrhea; Drug | 1985 |
64 other studies available for penicillamine and Dermatitis Medicamentosa
| Article | Year |
|---|---|
Epidermolysis bullosa acquisita-like eruption with anticollagen VII autoantibodies induced by D-penicillamine in Wilson disease.
Topics: Adult; Autoantibodies; Chelating Agents; Collagen Type VII; Drug Eruptions; Epidermolysis Bullosa Ac | 2014 |
Physical signs for the general dental practitioner. Case 88. D-Penicillamine rash.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Diagnosis, Differential; Drug Eruptions; Exanthema; Gen | 2011 |
Concurrent massive breast enlargement, myasthenia gravis and dermopathy as manifestations of penicillamine toxicity in a Wilson's disease patient.
Topics: Adolescent; Breast; Chelating Agents; Drug Eruptions; Female; Hepatolenticular Degeneration; Humans; | 2012 |
PENICILLAMINE THERAPY FOR HEPATOLENTICULAR DEGENERATION.
Topics: Amenorrhea; Avitaminosis; Bone and Bones; Copper; Desensitization, Immunologic; Diet; Drug Eruptions | 1964 |
Decline of anti-desmoglein 1 IgG ELISA scores by withdrawal of D-penicillamine in drug-induced pemphigus foliaceus.
Topics: Aged; Antirheumatic Agents; Autoantibodies; Cadherins; Desmoglein 1; Drug Eruptions; Enzyme-Linked I | 2005 |
An iatrogenic dermatosis with ulceration.
Topics: Adult; Chelating Agents; Drug Eruptions; Female; Hepatolenticular Degeneration; Humans; Penicillamin | 2005 |
Erythematous plaques on the flexural surfaces.
Topics: Adult; Antirheumatic Agents; Axilla; Diagnosis, Differential; Drug Eruptions; Female; Hepatolenticul | 2005 |
Familial pseudo pseudoxanthoma elasticum.
Topics: Cystinuria; Diagnosis, Differential; Drug Eruptions; Female; Humans; Middle Aged; Neck; Penicillamin | 2006 |
[D-penicillamin-induced elastosis perforans serpiginosa].
Topics: Adult; Drug Eruptions; Humans; Male; Penicillamine | 2007 |
[Present status of dermatology].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Eruptions; Female; Humans; Leg Ulcer; Lit | 1980 |
The long term effects of sulphasalazine in the treatment of rheumatoid arthritis and a comparative study with penicillamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Eruptions; Drug Tolerance; Dyspepsia; Female; Humans; Male; | 1984 |
Sequential gold and penicillamine therapy in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Drug Eruptions; gamma-Globulins; Gold; HLA Antigens; HLA-B Antigens; H | 1982 |
Deposition of immunoglobulin and complement in mucocutaneous lesions related to treatment with D-penicillamine.
Topics: Adult; Complement System Proteins; Drug Eruptions; Fluorescent Antibody Technique; Humans; Immunoglo | 1982 |
Prior gold therapy does not influence the adverse effects of D-penicillamine in rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Drug Eruptions; Drug Interactions; Dysgeusia; | 1982 |
Multiple side effects of penicillamine therapy in one patient with rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Drug Eruptions; Humans; Lupus Erythematosus, Systemic; Male; Myastheni | 1982 |
Observations on drug-induced toxic epidermal necrolysis in Singapore.
Topics: Adult; Aged; Anti-Inflammatory Agents; Antipyrine; Barbiturates; Burns; Child; Diagnosis, Differenti | 1984 |
[Skin manifestations observed during treatment with penicillamine and its derivatives].
Topics: Drug Eruptions; Elastic Tissue; Humans; Pemphigus; Penicillamine; Penicillins; Pyrithioxin; Skin Dis | 1984 |
Morphea-like reaction to D-penicillamine therapy.
Topics: Adult; Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Penicillamine; Scleroderma, Localized; | 1981 |
Ultrastructure of penicillamine-induced skin lesions.
Topics: Adult; Collagen; Drug Eruptions; Elastic Tissue; Epidermis; Fibroblasts; Hemorrhage; Humans; Male; M | 1981 |
Pemphigus-like eruption due to penicillamine.
Topics: Arthritis, Rheumatoid; Diagnosis, Differential; Drug Eruptions; Humans; Male; Middle Aged; Pemphigus | 1981 |
Penicillamine-induced lupus-like reaction in rheumatoid arthritis and vasculitis.
Topics: Adult; Antibodies, Antinuclear; Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Lupus Erythem | 1981 |
[Chlorbutin, azathioprine, D-penicillamine, and levamisole (Decaris) in the treatment of rheumatoid arthritis patients. I. Comparative analysis of side effects].
Topics: Arthritis, Rheumatoid; Azathioprine; Bronchial Spasm; Chlorambucil; Drug Eruptions; Dyspepsia; Human | 1981 |
Penicillamine-induced dermal fragility in Wilson's disease (hepato-lenticular degeneration).
Topics: Adult; Drug Eruptions; Hepatolenticular Degeneration; Humans; Male; Penicillamine; Skin | 1981 |
Efficacy and toxicity of D-penicillamine for rheumatoid disease in the elderly.
Topics: Adult; Age Factors; Aged; Arthritis, Rheumatoid; Drug Eruptions; Female; Gastrointestinal Diseases; | 1982 |
[Penicillamine-induced elastosis perforans serpiginosa].
Topics: Adult; Darier Disease; Diagnosis, Differential; Drug Eruptions; Elastic Tissue; Hepatolenticular Deg | 1994 |
Contact allergy to penicillamine in eyedrops.
Topics: Aged; Burns, Chemical; Calcium Compounds; Drug Eruptions; Eye Burns; Eyelid Diseases; Humans; Male; | 1993 |
[Pemphigus foliaceus caused by penicillamine].
Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Complement C3; Drug Eruptions; Female; Fluorescent A | 1993 |
Diffuse blisters and erosions in a patient with limited scleroderma. Penicillamine-induced pemphigus foliaceus (PIPF).
Topics: Aged; Blister; Drug Eruptions; Female; Humans; Pemphigus; Penicillamine; Scleroderma, Localized | 1997 |
Successful treatment of recalcitrant penicillamine-induced pemphigus foliaceus by low-dose intravenous immunoglobulins.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Immunoglobulins, Intrav | 1999 |
Factors that modify penicillamine-induced autoimmunity in Brown Norway rats: failure of the Th1/Th2 paradigm.
Topics: Animals; Autoimmune Diseases; Autoimmunity; Drug Eruptions; Immunoglobulin E; Interferon Inducers; I | 2001 |
Clinical and histological spectrum of elastotic changes induced by penicillamine.
Topics: Aged; Chelating Agents; Cutis Laxa; Drug Eruptions; Humans; Male; Penicillamine; Skin | 2002 |
Editorial: D-penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Blood Cell Count; Drug Eruptions; Humans; Penicillamine; Proteinuria; Thrombo | 1975 |
[Adverse effects of drugs on the skin--significance, survey and prospects].
Topics: Adrenergic beta-Antagonists; Allergens; Alopecia; Bleomycin; Drug Eruptions; Humans; Melanoma; Metho | 1978 |
Chelation therapy in lead nephropathy.
Topics: Acute Kidney Injury; Administration, Oral; Chelating Agents; Creatinine; Dimercaprol; Drug Eruptions | 1975 |
Pemphigus-like syndrome induced by D-penicillamine.
Topics: Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Middle Aged; Pemphigus; Penicillamine; Syndro | 1976 |
Pemphigus in a patient treated with penicillamine for generalized morphea.
Topics: Drug Eruptions; Female; Humans; Middle Aged; Pemphigus; Penicillamine; Scleroderma, Localized | 1976 |
Side-effects of long-term D-penicillamine therapy in rheumatoid arthritis.
Topics: Agranulocytosis; Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Middle Aged; Neutropenia; Pe | 1977 |
[Adverse effects of penicillamine].
Topics: Adult; Drug Eruptions; Edema; Female; Humans; Male; Penicillamine; Proteinuria | 1978 |
Penicillamine and previous treatment with gold.
Topics: Arthritis, Rheumatoid; Bone Marrow Diseases; Drug Eruptions; Gold; Humans; Penicillamine; Sjogren's | 1978 |
Skin changes caused by D-penicillamine treatment of arthritis. Report of three cases with immunological findings.
Topics: Arthritis; Child; Drug Eruptions; Female; Humans; Immunoglobulin G; Male; Middle Aged; Penicillamine | 1978 |
[Pemphigus syndrome in D-penicillamine treated rheumatoid arthritis].
Topics: Adult; Arthritis, Rheumatoid; Drug Eruptions; Female; Humans; Pemphigus; Penicillamine; Syndrome | 1978 |
Two cases of penicillamine-induced pemphigus erythematosus.
Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Drug Eruptions; Female; Humans; Middle Aged; Pemphigus; P | 1979 |
Skin and bone lesions (dermato-osteolathyrism), possible side effects of D-penicillamine treatment, in a boy with cystinuria.
Topics: Atrophy; Bicarbonates; Bone and Bones; Bone Diseases; Child, Preschool; Cystinuria; Drug Eruptions; | 1979 |
D-penicillamine toxicity in Greek patients with rheumatoid arthritis: anti-Ro(SSA) antibodies and cryoglobulinemia are predictive factors.
Topics: Antibodies, Antinuclear; Arthritis, Rheumatoid; Cryoglobulinemia; Drug Eruptions; Female; Fluorescen | 1991 |
[Cutaneous side effects induced by D-penicillamine in the treatment of rheumatoid arthritis].
Topics: Antibodies; Arthritis, Rheumatoid; Cell Nucleus; DNA; Drug Eruptions; Female; Humans; Middle Aged; P | 1990 |
[Long-term tolerability of tiopronin (Acadione) in the treatment of rheumatoid arthritis. Apropos of 140 personal cases].
Topics: Arthritis, Rheumatoid; Drug Eruptions; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Mal | 1990 |
Lupus erythematosus-like eruption due to D-penicillamine in progressive systemic sclerosis.
Topics: Drug Eruptions; Female; Humans; Lupus Erythematosus, Cutaneous; Middle Aged; Penicillamine; Sclerode | 1990 |
Contact allergy to d-penicillamine.
Topics: Adult; Dermatitis, Contact; Drug Eruptions; Humans; Male; Ophthalmic Solutions; Patch Tests; Penicil | 1990 |
Fatal penicillamine-induced pemphigus foliaceus-like dermatosis.
Topics: Adult; Bacterial Infections; Drug Eruptions; Humans; Male; Middle Aged; Pemphigus; Penicillamine | 1986 |
The toxicity of D-penicillamine in systemic sclerosis.
Topics: Arthritis, Rheumatoid; Digestive System Diseases; Dose-Response Relationship, Drug; Drug Eruptions; | 1986 |
European League against Rheumatism study of adverse reactions to D-penicillamine.
Topics: Aged; Arthritis, Rheumatoid; Drug Eruptions; Europe; Female; Gastrointestinal Diseases; Hematologic | 1986 |
Penicillamine-induced bullous pemphigoid-like eruption.
Topics: Arthritis, Rheumatoid; Drug Eruptions; Humans; Male; Middle Aged; Pemphigoid, Bullous; Penicillamine | 1987 |
Toxicity to D-penicillamine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Drug Eruptions; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; | 1987 |
[An unusual cutaneous reaction pattern as a side effect of penicillamine: elastosis perforans serpiginosa].
Topics: Adult; Cystinuria; Drug Eruptions; Elastic Tissue; Female; Hepatolenticular Degeneration; Humans; Ma | 1988 |
[Pemphigus herpetiformis following D-penicillamine in a patient with HLA B8].
Topics: Arthritis, Rheumatoid; Dermatitis Herpetiformis; Drug Eruptions; HLA-B Antigens; HLA-B8 Antigen; Hum | 1988 |
HLA antigens and adverse drug reactions to sodium aurothiomalate and D-penicillamine in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Diarrhea; Drug Eruptions; Female; Gold Sodium Thiomalate; Histoc | 1985 |
Penicillamine-induced pemphigus foliaceus-like dermatosis. A case with unusual features, successfully treated by plasmapheresis.
Topics: Dermatitis, Exfoliative; Drug Eruptions; Humans; Male; Middle Aged; Pemphigus; Penicillamine; Plasma | 1985 |
Penicillamine-induced skin lesions. A possible example of human lathyrism.
Topics: Adult; Cysts; Drug Eruptions; Hepatolenticular Degeneration; Humans; Lathyrism; Male; Penicillamine | 1967 |
D-penicillamine for the treatment of gold dermatitis.
Topics: Activation Analysis; Arthritis, Rheumatoid; Drug Eruptions; Feces; Female; Gold; Humans; Middle Aged | 1969 |
[Late cutaneous lesions due to penicillamine in a patient with Wilson's disease].
Topics: Adolescent; Drug Eruptions; Exanthema; Hepatolenticular Degeneration; Humans; Leg Dermatoses; Male; | 1969 |
[Clinical, therapeutic and isotopic study of familial Wilson's disease: desensitization to penicillamine D].
Topics: Adult; Child; Child, Preschool; Copper; Desensitization, Immunologic; Drug Eruptions; Female; Hepato | 1969 |
[Lupoid syndrome due to D-penicillamine associated with Wilson's disease: immunologic study by leukocyte migration test (L.M.T.)].
Topics: Cell Movement; Drug Eruptions; Female; Hepatolenticular Degeneration; Humans; Leukocytes; Lupus Vulg | 1971 |
Febrile penicillamine eruption.
Topics: Antigen-Antibody Complex; Asian People; Drug Eruptions; Hepatolenticular Degeneration; Humans; Penic | 1972 |
[Dermatological complications during treatment of Wilsons disease with D-penicillamine].
Topics: Adolescent; Adult; Agammaglobulinemia; Drug Eruptions; Female; Hepatolenticular Degeneration; Humans | 1973 |