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penicillamine and Deficiency, Pyridoxine

penicillamine has been researched along with Deficiency, Pyridoxine in 27 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Research Excerpts

ExcerptRelevanceReference
"The effects of pyridoxine deficiency and the administration of supplemental vitamin B6 on audiogenic and electroconvulsive seizures were studied in two inbred strains of mice and their F1 hybrids."7.65Levels of pyridoxine and susceptibility to electroconvulsive and audiogenic seizures. ( Lieff, B; Schlesinger, K, 1975)
"The effects of pyridoxine deficiency and the administration of supplemental vitamin B6 on audiogenic and electroconvulsive seizures were studied in two inbred strains of mice and their F1 hybrids."3.65Levels of pyridoxine and susceptibility to electroconvulsive and audiogenic seizures. ( Lieff, B; Schlesinger, K, 1975)
"In most instances, overt symptoms of vitamin B6 deficiency due to chronic ingestion of these drugs are observed, and neurological problems seem to be rather frequent."2.36Drug--vitamin B6 interaction. ( Bhagavan, HN; Brin, M, 1983)
"A chronic vitamin B6 deficiency in rats resulted in a non-specific increase (44- 51%) in the in vitro intestinal uptake of both essential (Ca and Zn) and non-essential toxic metal (Cd) ions, whereas an acute B6-deficient state only affected the Zn uptake rate."1.26Effect of vitamin B6 and B1 deficiencies on the intestinal uptake of calcium, zinc and cadmium. ( Lyall, V; Nath, R; Prasad, R, 1982)
"The growth of 9A and 7316A Morris hepatomas was studied in pyridoxine (PN)-depleted and in pair-fed control Buffalo rats."1.26Control of tumor growth by pyridoxine restriction or treatment with an antivitamin agent. ( Tryfiates, GP, 1981)
" These data indicate that D-PeA is not capable of producing VB6 deficiency in the dosage employed in patients."1.26[Effect of D-penicillamine on vitamine B6 and collagen metabolism (author's transl)]. ( Kajiwara, T, 1979)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199026 (96.30)18.7374
1990's1 (3.70)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
TU, J1
BLACKWELL, RQ1
LEE, PF1
LITTMAN, ML2
TAGUCHI, T3
SHIMIZU, Y2
ASATOOR, AM2
LYLE, WH1
COLLINI, WR1
MATTERN, SR1
SHAPIRO, P1
HARRIS, RC1
ZINSSER, HH1
Seelig, MS2
Bhagavan, HN1
Brin, M1
Rothschild, B1
Prasad, R1
Lyall, V1
Nath, R1
Rumsby, PC1
Shepherd, DM1
Tryfiates, GP1
Rees, MM1
Rodgers, GM1
Kajiwara, T1
Okada, M1
Abe, M1
Schlesinger, K1
Lieff, B1
Gibbs, K2
Walshe, JM2
Baumgartner, R2
Obenaus, H2
Stoerk, HC2
Jaffe, IA1
Chadha, AK1
Dawson, IM1
Milne, MD1
Prosser, DI1
Smith, DB1
Gallagher, BB1
Takami, M1
Fujioka, M1
Wada, H1
Jacobus, D1
Grenan, M1
Wagner, B1
Margolis, C1
Jaffe, I1
Sutton, GG1
Oldstone, MB1

Reviews

3 reviews available for penicillamine and Deficiency, Pyridoxine

ArticleYear
Drug--vitamin B6 interaction.
    Current concepts in nutrition, 1983, Volume: 12

    Topics: Contraceptives, Oral; Cycloserine; Ethanol; Humans; Hydrazines; Levodopa; Nutritional Requirements;

1983
Homocysteinemia: association of a metabolic disorder with vascular disease and thrombosis.
    Thrombosis research, 1993, Sep-01, Volume: 71, Issue:5

    Topics: Adult; Amino Acid Metabolism, Inborn Errors; Blood Coagulation Factors; Blood Platelets; Child; Cyst

1993
The antivitamin B 6 effect of penicillamine: clinical and immunological implications.
    Advances in biochemical psychopharmacology, 1972, Volume: 4

    Topics: Antibody Formation; Arthritis, Rheumatoid; Drug Antagonism; Drug Interactions; Humans; Immunosuppres

1972

Other Studies

24 other studies available for penicillamine and Deficiency, Pyridoxine

ArticleYear
DL-penicillamine as a cause of optic axial neuritis.
    JAMA, 1963, Jul-13, Volume: 185

    Topics: Chelating Agents; Humans; Neuritis; Optic Neuritis; Penicillamine; Vitamin B 6 Deficiency

1963
RETARDING EFFECT OF VITAMIN DEFICIENT AND CHOLESTEROL FREE DIETS ON GROWTH OF SARCOMA 180.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1964, Volume: 116

    Topics: Animals; Avitaminosis; Cholesterol; Diet; Dietary Fats; Mice; Penicillamine; Pharmacology; Research;

1964
GROWTH-RETARDING EFFECT OF ORAL L-PENICILLAMINE ON SARCOMA-180.
    Nature, 1964, Aug-15, Volume: 203

    Topics: Animals; Mice; Penicillamine; Pharmacology; Research; Sarcoma 180; Vitamin B 6 Deficiency

1964
PYRIDOXINE DEFICIENCY IN THE RAT PRODUCED BY D-PENICILLAMINE.
    Nature, 1964, Sep-26, Volume: 203

    Topics: Chromatography; Kynurenic Acid; Penicillamine; Pharmacology; Rats; Research; Toxicology; Urine; Vita

1964
PENICILLAMINE AND CYSTINURIA.
    British medical journal, 1964, Nov-28, Volume: 2, Issue:5421

    Topics: Cystinuria; Humans; Metabolism; Penicillamine; Toxicology; Vitamin B 6 Deficiency

1964
METHODS OF DIMINISHING CYSTINE EXCRETION IN CYSTINURIA.
    The Journal of urology, 1965, Volume: 93

    Topics: Acetylcysteine; Amino Acids; Cysteine; Cystine; Cystinuria; Diet; Diet Therapy; Drug Therapy; Fluids

1965
Penicillamine and the nephrotic syndrome.
    JAMA, 1967, Mar-06, Volume: 199, Issue:10

    Topics: Humans; Nephrotic Syndrome; Penicillamine; Vitamin B 6 Deficiency

1967
Pyridoxine deficiency.
    Archives of internal medicine, 1982, Volume: 142, Issue:4

    Topics: Humans; Penicillamine; Vitamin B 6 Deficiency

1982
Effect of vitamin B6 and B1 deficiencies on the intestinal uptake of calcium, zinc and cadmium.
    Annals of nutrition & metabolism, 1982, Volume: 26, Issue:5

    Topics: Animals; Cadmium; Calcium; Intestinal Absorption; Penicillamine; Rats; Thiamine Deficiency; Vitamin

1982
Auto-immune complications of D-penicillamine--a possible result of zinc and magnesium depletion and of pyridoxine inactivation.
    Journal of the American College of Nutrition, 1982, Volume: 1, Issue:2

    Topics: Autoimmune Diseases; Humans; Magnesium; Magnesium Deficiency; Penicillamine; Pyridoxine; Vitamin B 6

1982
The effect of penicillamine on vitamin B6 function in man.
    Biochemical pharmacology, 1981, Nov-15, Volume: 30, Issue:22

    Topics: Alanine Transaminase; Erythrocytes; Humans; Penicillamine; Vitamin B 6 Deficiency

1981
Control of tumor growth by pyridoxine restriction or treatment with an antivitamin agent.
    Cancer detection and prevention, 1981, Volume: 4, Issue:1-4

    Topics: Animals; Female; Liver Neoplasms, Experimental; Neoplasms, Experimental; Penicillamine; Pyridoxine;

1981
[Effect of D-penicillamine on vitamine B6 and collagen metabolism (author's transl)].
    Nihon Seikeigeka Gakkai zasshi, 1979, Volume: 53, Issue:11

    Topics: Aldehydes; Amino Acids; Animals; Body Weight; Bone and Bones; Brain Chemistry; Collagen; Male; Penic

1979
Alanine metabolism in pyridoxine-depleted rat liver.
    Journal of nutritional science and vitaminology, 1976, Volume: 22, Issue:2

    Topics: Alanine; Alanine Transaminase; Animals; Blood Glucose; Carbon Dioxide; Gluconeogenesis; Ketoglutaric

1976
Levels of pyridoxine and susceptibility to electroconvulsive and audiogenic seizures.
    Psychopharmacologia, 1975, Apr-30, Volume: 42, Issue:1

    Topics: Acoustic Stimulation; Animal Feed; Animals; Brain Chemistry; Electroshock; Genotype; Mice; Mice, Inb

1975
Penicillamine and pyridoxine requirements in man.
    Lancet (London, England), 1966, Jan-22, Volume: 1, Issue:7430

    Topics: Adult; Animals; Child; Chromatography, Paper; Epilepsies, Partial; Female; Hepatolenticular Degenera

1966
Proceedings: Suppression of adjuvant arthritis by DL-penicillamine in vitamin B6 deficient rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:Suppl

    Topics: Adjuvants, Immunologic; Animals; Arthritis; Diet; Penicillamine; Pyridoxine; Rats; Vitamin B 6 Defic

1974
Suppression of adjuvant arthritis by penicillamine in pyridoxine deficient rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1974, Volume: 146, Issue:1

    Topics: Animals; Arthritis; Freund's Adjuvant; Male; Penicillamine; Rats; Vitamin B 6 Deficiency

1974
The effect of pyridoxine deficiency on intestinal absorption of amino acids and peptides in the rat.
    The British journal of nutrition, 1972, Volume: 28, Issue:3

    Topics: Alanine; Amino Acids; Animals; Dipeptides; Glycine; Intestinal Absorption; Jejunum; Leucine; Male; M

1972
Interruption of the tryptophan-nicotinic acid pathway by penicillamine-induced pyridoxine deficiency in patients with Wilson's disease and in experimental animals.
    Annals of the New York Academy of Sciences, 1969, Sep-30, Volume: 166, Issue:1

    Topics: Animals; Carbon Isotopes; Chromatography; Female; Hepatolenticular Degeneration; Humans; Kynurenine;

1969
The effect of penicillamine on seizure threshold. The role of pyridoxine.
    Archives of neurology, 1970, Volume: 23, Issue:1

    Topics: Animals; Disease Models, Animal; Male; Myoclonus; Penicillamine; Pyridoxine; Rats; Seizures; Tryptop

1970
Studies on pyridoxine deficiency in rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1968, Volume: 129, Issue:1

    Topics: Animals; Body Weight; Carbon Isotopes; DNA; Enzymes; Hepatectomy; Liver; Liver Regeneration; Methods

1968
Osteolathyrogenic effect of penicillamine.
    The American journal of pathology, 1969, Volume: 54, Issue:1

    Topics: Animals; Bone and Bones; Connective Tissue; Diet; Epiphyses; Female; Lathyrism; Mice; Penicillamine;

1969
Evidence against pyridoxine deficiency as the mechanism of penicillin seizures.
    Neurology, 1969, Volume: 19, Issue:9

    Topics: Animals; Cats; Cerebral Cortex; Electroencephalography; Methanol; Penicillamine; Penicillins; Pyridi

1969