Page last updated: 2024-11-07

penicillamine and Cutis Laxa

penicillamine has been researched along with Cutis Laxa in 14 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Cutis Laxa: A group of connective tissue diseases in which skin hangs in loose pendulous folds. It is believed to be associated with decreased elastic tissue formation as well as an abnormality in elastin formation. Cutis laxa is usually a genetic disease, but acquired cases have been reported. (From Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"A patient with Wilson's disease who developed elastosis perforans serpiginosa and localized cutis laxa during prolonged treatment with D-penicillamine is described."7.69D-penicillamine-induced elastosis perforans serpiginosa and localized cutis laxa in a patient with Wilson's disease. ( Amichai, B; Metzker, A; Rotem, A, 1994)
"We report a chromosomally normal infant boy with congenital diffuse cutis laxa, severe micrognathia, contractures of all limbs, and central nervous system abnormalities including agenesis of the corpus callosum, born to a woman taking D-penicillamine (DP) for Wilson disease (WD) throughout her pregnancy."3.72Infant with severe penicillamine embryopathy born to a woman with Wilson disease. ( Hogge, WA; McPherson, E; Pinter, R, 2004)
"A patient with Wilson's disease who developed elastosis perforans serpiginosa and localized cutis laxa during prolonged treatment with D-penicillamine is described."3.69D-penicillamine-induced elastosis perforans serpiginosa and localized cutis laxa in a patient with Wilson's disease. ( Amichai, B; Metzker, A; Rotem, A, 1994)
"Excellent treatment options exist for Wilson disease, based on copper chelation."2.49Inborn errors of copper metabolism. ( Kaler, SG, 2013)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19906 (42.86)18.7374
1990's1 (7.14)18.2507
2000's4 (28.57)29.6817
2010's3 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaler, SG1
Hellriegel, S1
Bertsch, HP1
Emmert, S1
Schön, MP1
Haenssle, HA1
Vajdi, T1
Lee, WW1
Paravar, T1
Pinter, R1
Hogge, WA1
McPherson, E1
Rosen, LB1
Muellenhoff, M1
Tran, TT1
Muhart, M1
Harpey, JP1
Jaudon, MC1
Clavel, JP1
Galli, A1
Darbois, Y1
Amichai, B1
Rotem, A1
Metzker, A1
Hill, VA1
Seymour, CA1
Mortimer, PS1
Poon, E1
Mason, GH1
Oh, C1
Siegel, RC1
Linares, A1
Zarranz, JJ1
Rodriguez-Alarcon, J1
Diaz-Perez, JL1
Walshe, JM1
Grahame, R1
Harvey, W1
Rosa, FW1

Reviews

3 reviews available for penicillamine and Cutis Laxa

ArticleYear
Inborn errors of copper metabolism.
    Handbook of clinical neurology, 2013, Volume: 113

    Topics: Chelating Agents; Child; Copper; Cutis Laxa; Ehlers-Danlos Syndrome; Hepatolenticular Degeneration;

2013
Penicillamine-associated cutis laxa and milia en plaque - case report and review of cutaneous changes associated with penicillamine.
    Dermatology online journal, 2016, May-15, Volume: 22, Issue:5

    Topics: Aged; Chelating Agents; Cutis Laxa; Cystinuria; Humans; Male; Penicillamine; Sweat Gland Diseases

2016
Lysyl oxidase.
    International review of connective tissue research, 1979, Volume: 8

    Topics: Amino Acid Oxidoreductases; Aneurysm; Animals; Chickens; Collagen; Copper; Cutis Laxa; Dogs; Ehlers-

1979

Other Studies

11 other studies available for penicillamine and Cutis Laxa

ArticleYear
Elastosis perforans serpiginosa: a case of a penicillamine-induced degenerative dermatosis.
    JAMA dermatology, 2014, Volume: 150, Issue:7

    Topics: Aged; Chelating Agents; Cutis Laxa; Hepatolenticular Degeneration; Humans; Male; Middle Aged; Penici

2014
Infant with severe penicillamine embryopathy born to a woman with Wilson disease.
    American journal of medical genetics. Part A, 2004, Jul-30, Volume: 128A, Issue:3

    Topics: Abnormalities, Drug-Induced; Agenesis of Corpus Callosum; Cutis Laxa; Female; Fetal Diseases; Fetus;

2004
Elastosis perforans serpiginosa secondary to D-penicillamine therapy with coexisting cutis laxa.
    Cutis, 2005, Volume: 76, Issue:1

    Topics: Chelating Agents; Connective Tissue Diseases; Cutis Laxa; Female; Humans; Middle Aged; Penicillamine

2005
Cutis laxa and low serum zinc after antenatal exposure to penicillamine.
    Lancet (London, England), 1983, Oct-08, Volume: 2, Issue:8354

    Topics: Adult; Cutis Laxa; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Penicillamine; Pregnanc

1983
D-penicillamine-induced elastosis perforans serpiginosa and localized cutis laxa in a patient with Wilson's disease.
    Israel journal of medical sciences, 1994, Volume: 30, Issue:8

    Topics: Child; Connective Tissue Diseases; Cutis Laxa; Elastic Tissue; Female; Hepatolenticular Degeneration

1994
Pencillamine-induced elastosis perforans serpiginosa and cutis laxa in Wilson's disease.
    The British journal of dermatology, 2000, Volume: 142, Issue:3

    Topics: Adult; Chelating Agents; Cutis Laxa; Elastic Tissue; Hepatolenticular Degeneration; Humans; Male; Pe

2000
Clinical and histological spectrum of elastotic changes induced by penicillamine.
    The Australasian journal of dermatology, 2002, Volume: 43, Issue:2

    Topics: Aged; Chelating Agents; Cutis Laxa; Drug Eruptions; Humans; Male; Penicillamine; Skin

2002
Reversible cutis laxa due to maternal D-penicillamine treatment.
    Lancet (London, England), 1979, Jul-07, Volume: 2, Issue:8132

    Topics: Cutis Laxa; Female; Fetus; Hepatolenticular Degeneration; Humans; Infant, Newborn; Infant, Newborn,

1979
Congenital cutis laxa and maternal D-penicillamine.
    Lancet (London, England), 1979, Jul-21, Volume: 2, Issue:8134

    Topics: Cutis Laxa; Female; Fetus; Humans; Infant, Newborn; Penicillamine; Pregnancy

1979
Cutaneous extensibility in health and disease.
    Rheumatology and rehabilitation, 1975, Volume: 14, Issue:2

    Topics: Acromegaly; Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Collagen; Cutis Laxa; Ehlers-Da

1975
Teratogen update: penicillamine.
    Teratology, 1986, Volume: 33, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Collagen; Copper; Cutis Laxa; Female; Hepatolenticular Degener

1986