penicillamine has been researched along with Connective Tissue Diseases in 15 studies
Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.
Connective Tissue Diseases: A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with Wilson's disease who developed elastosis perforans serpiginosa and localized cutis laxa during prolonged treatment with D-penicillamine is described." | 7.69 | D-penicillamine-induced elastosis perforans serpiginosa and localized cutis laxa in a patient with Wilson's disease. ( Amichai, B; Metzker, A; Rotem, A, 1994) |
| "The action of D-penicillamine on collagen can cause undesired side-effects in the treatment of cystinuria and Wilson's disease, it is on the other hand essential to the therapy of rheumatoid arthritis and scleroderma." | 7.66 | D-penicillamine in pregnancy--to ban or not to ban? ( Endres, W, 1981) |
| "A patient with Wilson's disease who developed elastosis perforans serpiginosa and localized cutis laxa during prolonged treatment with D-penicillamine is described." | 3.69 | D-penicillamine-induced elastosis perforans serpiginosa and localized cutis laxa in a patient with Wilson's disease. ( Amichai, B; Metzker, A; Rotem, A, 1994) |
| "The action of D-penicillamine on collagen can cause undesired side-effects in the treatment of cystinuria and Wilson's disease, it is on the other hand essential to the therapy of rheumatoid arthritis and scleroderma." | 3.66 | D-penicillamine in pregnancy--to ban or not to ban? ( Endres, W, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (53.33) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barsotti, S | 1 |
| Tripoli, A | 1 |
| Pollina, LE | 1 |
| Mosca, M | 1 |
| Neri, R | 1 |
| Deguti, MM | 1 |
| Mucenic, M | 1 |
| Cancado, EL | 1 |
| Tietge, UJ | 1 |
| Roest, MA | 1 |
| Ratnavel, R | 1 |
| Rosen, LB | 1 |
| Muellenhoff, M | 1 |
| Tran, TT | 1 |
| Muhart, M | 1 |
| Chvapil, M | 1 |
| Kielar, F | 1 |
| Liska, F | 1 |
| Silhankova, A | 1 |
| Brendel, K | 1 |
| Lorenzen, I | 1 |
| Brouilhet, H | 1 |
| Rabaud, M | 1 |
| Boucherie, S | 1 |
| Mach, PS | 1 |
| Delbarre, F | 1 |
| Dryll, A | 1 |
| Endres, W | 1 |
| Bardach, H | 1 |
| Gebhart, W | 1 |
| Ehrlich, GE | 1 |
| Yeowell, HN | 1 |
| Marshall, MK | 1 |
| Walker, LC | 1 |
| Ha, V | 1 |
| Pinnell, SR | 1 |
| Amichai, B | 1 |
| Rotem, A | 1 |
| Metzker, A | 1 |
| Junker, P | 1 |
| Last, JA | 1 |
| Meyrick Thomas, RH | 1 |
| Kirby, JD | 1 |
4 reviews available for penicillamine and Connective Tissue Diseases
| Article | Year |
|---|---|
Histopathology of the muscle in rheumatic diseases.
Topics: Adrenal Cortex Hormones; Biopsy; Connective Tissue Diseases; Cyclosporine; Diagnosis, Differential; | 2018 |
Pharmacological control of inflammatory connective tissue diseases.
Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Connective Tissue Diseases; Glucocorticoids; Humans | 1981 |
D-penicillamine effects on inflammatory and normal connective tissues in rats. Studies on collagen, glycosaminoglycans and nucleic acids with particular reference to antirheumatoid therapy.
Topics: Animals; Collagen; Connective Tissue; Connective Tissue Diseases; DNA; Glycosaminoglycans; Inflammat | 1985 |
Changes in the collagen pathway in fibrosis.
Topics: Animals; Anti-Inflammatory Agents; Colchicine; Collagen; Connective Tissue Diseases; Cross-Linking R | 1985 |
11 other studies available for penicillamine and Connective Tissue Diseases
| Article | Year |
|---|---|
Elastosis perforans serpiginosa secondary to D-penicillamine treatment in a Wilson's disease patient.
Topics: Adolescent; Antirheumatic Agents; Arm; Connective Tissue Diseases; Hepatolenticular Degeneration; Hu | 2002 |
Elastosis perforans serpiginosa of the penis.
Topics: Adult; Chelating Agents; Connective Tissue Diseases; Cystinuria; Elastic Tissue; Humans; Kidney Calc | 2003 |
Elastosis perforans serpiginosa secondary to D-penicillamine therapy with coexisting cutis laxa.
Topics: Chelating Agents; Connective Tissue Diseases; Cutis Laxa; Female; Humans; Middle Aged; Penicillamine | 2005 |
Synthesis and evaluation of long-acting D-penicillamine derivatives.
Topics: Adenocarcinoma; Alcohols; Aminopropionitrile; Animals; Cicatrix, Hypertrophic; Collagen; Connective | 2005 |
Comparison of effects of D. Penicillamine and dexamethasone on the articular and non articular lesions in immune connective tissue disease induced in rabbits.
Topics: Animals; Antibody Formation; Arthritis; Connective Tissue Diseases; Dexamethasone; Kidney; Liver; Lu | 1982 |
D-penicillamine in pregnancy--to ban or not to ban?
Topics: Arthritis, Rheumatoid; Connective Tissue Diseases; Cystinuria; Female; Hepatolenticular Degeneration | 1981 |
[Penicillamine-induced dermolytic dermatosis in a patient with Wilson's disease (author's transl)].
Topics: Adult; Connective Tissue Diseases; Female; Hepatolenticular Degeneration; Humans; Penicillamine; Ski | 1981 |
Dosage of penicillamine.
Topics: Bronchitis; Connective Tissue Diseases; Humans; Penicillamine | 1980 |
Regulation of lysyl oxidase mRNA in dermal fibroblasts from normal donors and patients with inherited connective tissue disorders.
Topics: Aminopropionitrile; Ascorbic Acid; Bleomycin; Cell Line; Collagen; Connective Tissue Diseases; DNA P | 1994 |
D-penicillamine-induced elastosis perforans serpiginosa and localized cutis laxa in a patient with Wilson's disease.
Topics: Child; Connective Tissue Diseases; Cutis Laxa; Elastic Tissue; Female; Hepatolenticular Degeneration | 1994 |
Elastosis perforans serpiginosa and pseudoxanthoma elasticum-like skin change due to D-penicillamine.
Topics: Child; Connective Tissue Diseases; Female; Humans; Penicillamine; Pseudoxanthoma Elasticum; Skin | 1985 |