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penicillamine and Connective Tissue Diseases

penicillamine has been researched along with Connective Tissue Diseases in 15 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Connective Tissue Diseases: A heterogeneous group of disorders, some hereditary, others acquired, characterized by abnormal structure or function of one or more of the elements of connective tissue, i.e., collagen, elastin, or the mucopolysaccharides.

Research Excerpts

ExcerptRelevanceReference
"A patient with Wilson's disease who developed elastosis perforans serpiginosa and localized cutis laxa during prolonged treatment with D-penicillamine is described."7.69D-penicillamine-induced elastosis perforans serpiginosa and localized cutis laxa in a patient with Wilson's disease. ( Amichai, B; Metzker, A; Rotem, A, 1994)
"The action of D-penicillamine on collagen can cause undesired side-effects in the treatment of cystinuria and Wilson's disease, it is on the other hand essential to the therapy of rheumatoid arthritis and scleroderma."7.66D-penicillamine in pregnancy--to ban or not to ban? ( Endres, W, 1981)
"A patient with Wilson's disease who developed elastosis perforans serpiginosa and localized cutis laxa during prolonged treatment with D-penicillamine is described."3.69D-penicillamine-induced elastosis perforans serpiginosa and localized cutis laxa in a patient with Wilson's disease. ( Amichai, B; Metzker, A; Rotem, A, 1994)
"The action of D-penicillamine on collagen can cause undesired side-effects in the treatment of cystinuria and Wilson's disease, it is on the other hand essential to the therapy of rheumatoid arthritis and scleroderma."3.66D-penicillamine in pregnancy--to ban or not to ban? ( Endres, W, 1981)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19908 (53.33)18.7374
1990's2 (13.33)18.2507
2000's4 (26.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barsotti, S1
Tripoli, A1
Pollina, LE1
Mosca, M1
Neri, R1
Deguti, MM1
Mucenic, M1
Cancado, EL1
Tietge, UJ1
Roest, MA1
Ratnavel, R1
Rosen, LB1
Muellenhoff, M1
Tran, TT1
Muhart, M1
Chvapil, M1
Kielar, F1
Liska, F1
Silhankova, A1
Brendel, K1
Lorenzen, I1
Brouilhet, H1
Rabaud, M1
Boucherie, S1
Mach, PS1
Delbarre, F1
Dryll, A1
Endres, W1
Bardach, H1
Gebhart, W1
Ehrlich, GE1
Yeowell, HN1
Marshall, MK1
Walker, LC1
Ha, V1
Pinnell, SR1
Amichai, B1
Rotem, A1
Metzker, A1
Junker, P1
Last, JA1
Meyrick Thomas, RH1
Kirby, JD1

Reviews

4 reviews available for penicillamine and Connective Tissue Diseases

ArticleYear
Histopathology of the muscle in rheumatic diseases.
    Reumatismo, 2018, Oct-03, Volume: 70, Issue:3

    Topics: Adrenal Cortex Hormones; Biopsy; Connective Tissue Diseases; Cyclosporine; Diagnosis, Differential;

2018
Pharmacological control of inflammatory connective tissue diseases.
    Progress in clinical and biological research, 1981, Volume: 54

    Topics: Anti-Inflammatory Agents; Antineoplastic Agents; Connective Tissue Diseases; Glucocorticoids; Humans

1981
D-penicillamine effects on inflammatory and normal connective tissues in rats. Studies on collagen, glycosaminoglycans and nucleic acids with particular reference to antirheumatoid therapy.
    Danish medical bulletin, 1985, Volume: 32, Issue:2

    Topics: Animals; Collagen; Connective Tissue; Connective Tissue Diseases; DNA; Glycosaminoglycans; Inflammat

1985
Changes in the collagen pathway in fibrosis.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1985, Volume: 5, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Colchicine; Collagen; Connective Tissue Diseases; Cross-Linking R

1985

Other Studies

11 other studies available for penicillamine and Connective Tissue Diseases

ArticleYear
Elastosis perforans serpiginosa secondary to D-penicillamine treatment in a Wilson's disease patient.
    The American journal of gastroenterology, 2002, Volume: 97, Issue:8

    Topics: Adolescent; Antirheumatic Agents; Arm; Connective Tissue Diseases; Hepatolenticular Degeneration; Hu

2002
Elastosis perforans serpiginosa of the penis.
    BJU international, 2003, Volume: 91, Issue:4

    Topics: Adult; Chelating Agents; Connective Tissue Diseases; Cystinuria; Elastic Tissue; Humans; Kidney Calc

2003
Elastosis perforans serpiginosa secondary to D-penicillamine therapy with coexisting cutis laxa.
    Cutis, 2005, Volume: 76, Issue:1

    Topics: Chelating Agents; Connective Tissue Diseases; Cutis Laxa; Female; Humans; Middle Aged; Penicillamine

2005
Synthesis and evaluation of long-acting D-penicillamine derivatives.
    Connective tissue research, 2005, Volume: 46, Issue:4-5

    Topics: Adenocarcinoma; Alcohols; Aminopropionitrile; Animals; Cicatrix, Hypertrophic; Collagen; Connective

2005
Comparison of effects of D. Penicillamine and dexamethasone on the articular and non articular lesions in immune connective tissue disease induced in rabbits.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1982, Volume: 36, Issue:6-7

    Topics: Animals; Antibody Formation; Arthritis; Connective Tissue Diseases; Dexamethasone; Kidney; Liver; Lu

1982
D-penicillamine in pregnancy--to ban or not to ban?
    Klinische Wochenschrift, 1981, Jun-01, Volume: 59, Issue:11

    Topics: Arthritis, Rheumatoid; Connective Tissue Diseases; Cystinuria; Female; Hepatolenticular Degeneration

1981
[Penicillamine-induced dermolytic dermatosis in a patient with Wilson's disease (author's transl)].
    Dermatologica, 1981, Volume: 162, Issue:6

    Topics: Adult; Connective Tissue Diseases; Female; Hepatolenticular Degeneration; Humans; Penicillamine; Ski

1981
Dosage of penicillamine.
    JAMA, 1980, Apr-18, Volume: 243, Issue:15

    Topics: Bronchitis; Connective Tissue Diseases; Humans; Penicillamine

1980
Regulation of lysyl oxidase mRNA in dermal fibroblasts from normal donors and patients with inherited connective tissue disorders.
    Archives of biochemistry and biophysics, 1994, Volume: 308, Issue:1

    Topics: Aminopropionitrile; Ascorbic Acid; Bleomycin; Cell Line; Collagen; Connective Tissue Diseases; DNA P

1994
D-penicillamine-induced elastosis perforans serpiginosa and localized cutis laxa in a patient with Wilson's disease.
    Israel journal of medical sciences, 1994, Volume: 30, Issue:8

    Topics: Child; Connective Tissue Diseases; Cutis Laxa; Elastic Tissue; Female; Hepatolenticular Degeneration

1994
Elastosis perforans serpiginosa and pseudoxanthoma elasticum-like skin change due to D-penicillamine.
    Clinical and experimental dermatology, 1985, Volume: 10, Issue:4

    Topics: Child; Connective Tissue Diseases; Female; Humans; Penicillamine; Pseudoxanthoma Elasticum; Skin

1985