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penicillamine and Complications, Pregnancy

penicillamine has been researched along with Complications, Pregnancy in 49 studies

Penicillamine: 3-Mercapto-D-valine. The most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
penicillamine : An alpha-amino acid having the structure of valine substituted at the beta position with a sulfanyl group.

Research Excerpts

ExcerptRelevanceReference
"A case of successful pregnancy in a patient with Wilson's disease treated with D-penicillamine and zinc sulfate is presented."7.69Pregnancy in a patient with Wilson's disease treated with D-penicillamine and zinc sulfate. A case report and review of the literature. ( Hartard, C; Kunze, K, 1994)
" A regimen of d-penicillamine was started at this time and continued, although irregularly for the 10 months prior to her 9th week of pregnancy."7.67Pregnancy and penicillamine treatment in a patient with Wilson's disease. ( Komatsu, K; Morimoto, I; Ninomiya, H; Satho, M, 1986)
"The action of D-penicillamine on collagen can cause undesired side-effects in the treatment of cystinuria and Wilson's disease, it is on the other hand essential to the therapy of rheumatoid arthritis and scleroderma."7.66D-penicillamine in pregnancy--to ban or not to ban? ( Endres, W, 1981)
"The mother we present is a Wilson's disease patient who had been compliant with D-penicillamine for the preceding 13 years."5.32Transient fetal myelosuppressive effect of D-penicillamine when used in pregnancy. ( Akisu, M; Aydogdu, S; Kultursay, N; Ozgenc, F; Yagci, RV; Yalaz, M, 2003)
" D-Penicillamine may be teratogenic thus it should not be commenced during pregnancy and if a patient becomes pregnant whilst receiving the drug, it should be slowly withdrawn or the dosage reduced."4.77Antirheumatic medication in pregnancy. ( Brooks, PM; Needs, CJ, 1985)
"She was at 38 weeks and 4 days of gestation with a 15-year history of WD, controlled with penicillamine in the past and replaced by zinc preparations from three months before pregnancy."3.88Anesthetic management of cesarean delivery for a parturient with Wilson's disease: A case report. ( Jiang, X; Lin, X; Wan, Y, 2018)
"A case of successful pregnancy in a patient with Wilson's disease treated with D-penicillamine and zinc sulfate is presented."3.69Pregnancy in a patient with Wilson's disease treated with D-penicillamine and zinc sulfate. A case report and review of the literature. ( Hartard, C; Kunze, K, 1994)
" A regimen of d-penicillamine was started at this time and continued, although irregularly for the 10 months prior to her 9th week of pregnancy."3.67Pregnancy and penicillamine treatment in a patient with Wilson's disease. ( Komatsu, K; Morimoto, I; Ninomiya, H; Satho, M, 1986)
"46 pregnancies in patients with cystinuria treated with a high fluid intake alone or in combination with D-penicillamine resulted in 41 normal births."3.66Pregnancy and cystinuria. ( Gregory, MC; Mansell, MA, 1983)
"The action of D-penicillamine on collagen can cause undesired side-effects in the treatment of cystinuria and Wilson's disease, it is on the other hand essential to the therapy of rheumatoid arthritis and scleroderma."3.66D-penicillamine in pregnancy--to ban or not to ban? ( Endres, W, 1981)
" During treatment with the basic drugs: gold, D-penicillamine and chloroquine, pregnancy should be avoided."3.65[Problems of rheumatic therapy in pregnancy (author's transl)]. ( Bischof, P, 1976)
"The treatment of Wilson's disease has changed considerably in recent times, from the use of penicillamine (Cuprimine, Merck) for all stages and types of disease, to the use of three other anticopper drugs at appropriate times for appropriate patients."2.43Novel therapeutic approaches to the treatment of Wilson's disease. ( Brewer, GJ, 2006)
"Certain features of Wilson's disease (WD) in Asia have been found to be different from those in other continents."2.38Geographic variations in Wilson's disease. ( Chu, NS; Hung, TP, 1993)
"This article presents a case report of Wilson's disease in pregnancy and a review of this entity during gestation."2.36Hepatolenticular degeneration (Wilson's disease) and pregnancy. A review and report of a case. ( Peyser, MR; Streifler, M; Toaff, ME; Toaff, R, 1977)
"The mother we present is a Wilson's disease patient who had been compliant with D-penicillamine for the preceding 13 years."1.32Transient fetal myelosuppressive effect of D-penicillamine when used in pregnancy. ( Akisu, M; Aydogdu, S; Kultursay, N; Ozgenc, F; Yagci, RV; Yalaz, M, 2003)
"Wilson's disease is an autosomal recessive disorder of copper metabolism characterized mainly by liver cirrhosis and neurological disorders."1.31Wilson's disease in pregnancy: five successful consecutive pregnancies of the same woman. ( Bashiri, A; Erez, O; Furman, B; Holcberg, G; Mazor, M; Wiznitzer, A, 2001)
"Patients with Wilson's disease contemplating pregnancy should have their hepatic function and copper status assessed."1.29Wilson's disease in pregnancy. ( Goulding, P; Hawthorne, B; Maresh, M; Nunns, D, 1995)
"A patient with untreated Wilson's disease showed the possibility of fetal liver damage and copper accumulation in the placenta by this disease."1.29Copper disposition of the fetus and placenta in a patient with untreated Wilson's disease. ( Anai, T; Inoue, I; Matsui, N; Miyakawa, I; Oga, M; Yoshimatsu, J, 1993)
"Pregnancy in patients with Wilson's disease can be successfully managed."1.27Successful pregnancy in Wilson's disease: a case report and review of the literature. ( Biller, J; Brazis, PW; Swiontoniowski, M, 1985)
"The effect of pregnancy has been studied in 10 mothers with Wilson's disease."1.26Pregnancy in Wilson's disease. ( Walshe, JM, 1977)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199032 (65.31)18.7374
1990's10 (20.41)18.2507
2000's6 (12.24)29.6817
2010's1 (2.04)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wan, Y1
Jiang, X1
Lin, X1
Pérez-Aguilar, F1
Yalaz, M1
Aydogdu, S1
Ozgenc, F1
Akisu, M1
Kultursay, N1
Yagci, RV1
Brewer, GJ1
Gregory, MC1
Mansell, MA1
Endres, W1
Tojo, T1
Pigrau Serrallach, C1
Pahissa Berga, A1
Clotet Sala, B1
Guardia Massó, J1
Nunns, D1
Hawthorne, B1
Goulding, P1
Maresh, M1
Hartard, C1
Kunze, K1
Hull, AD1
Longo, LD1
Long, DM1
Pearce, WJ1
Oga, M1
Matsui, N1
Anai, T1
Yoshimatsu, J1
Inoue, I1
Miyakawa, I1
Chu, NS1
Hung, TP1
Martínez-Frías, ML1
Rodríguez-Pinilla, E1
Bermejo, E1
Blanco, M1
Mustafa, MS1
Shamina, AH1
Hlinst'ák, K1
Borovský, M1
Hlinst'áková, S1
Sternlieb, I2
Castilla-Higuero, L1
Romero-Gomez, M1
Suarez, E1
Castro, M1
Furman, B1
Bashiri, A1
Wiznitzer, A1
Erez, O1
Holcberg, G1
Mazor, M1
Arbisser, AI1
Scott, CI1
Howell, BR1
Lyle, WH1
Toaff, R1
Toaff, ME1
Peyser, MR1
Streifler, M1
Fukuda, K1
Ishii, A1
Matsue, Y1
Funaki, K1
Hoshiai, H1
Maeda, S1
Bischof, P1
Walshe, JM1
Milazzo, S1
Marecek, Z1
Graf, M1
Scheinberg, IH1
Albukerk, JN2
Chin, RK1
Dupont, P1
Irion, O1
Béguin, F1
Lewis, JH1
Weingold, AB1
Miehle, W1
Byron, MA1
Shekhtman, MM1
Koridze, RS1
Morimoto, I1
Ninomiya, H1
Komatsu, K1
Satho, M1
Rosa, FW1
Ostensen, M1
Husby, G1
Needs, CJ1
Brooks, PM1
Scarpinato, L1
Mackenzie, AH1
Biller, J1
Swiontoniowski, M1
Brazis, PW1
Mjolnerod, OK1
Dommerud, SA1
Rasmussen, K1
Gjeruldsen, ST1
Laver, M1
Fairley, KF1
Stähler, E1
Stähler, F1
Sturm, G1
Trux, F1
Haley, TJ1
Pierce, PE1
Thompson, JF1
Likosky, WH1
Nickey, LN1
Barthel, WF1
Hinman, AR1
Wenzl, H1
Kludas, M1

Reviews

10 reviews available for penicillamine and Complications, Pregnancy

ArticleYear
[Wilson's disease: physiopathological, clinical and therapeutic considerations].
    Gastroenterologia y hepatologia, 2003, Volume: 26, Issue:1

    Topics: Adenosine Triphosphatases; Adolescent; Adult; Basal Ganglia Diseases; Brain; Cation Transport Protei

2003
Novel therapeutic approaches to the treatment of Wilson's disease.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:3

    Topics: Chelating Agents; Child; Child, Preschool; Clinical Trials as Topic; Copper; Female; Hepatolenticula

2006
Geographic variations in Wilson's disease.
    Journal of the neurological sciences, 1993, Volume: 117, Issue:1-2

    Topics: Adolescent; Adult; Brain Diseases, Metabolic; Carcinoma, Hepatocellular; China; Comorbidity; Consang

1993
Wilson's disease and pregnancy.
    Hepatology (Baltimore, Md.), 2000, Volume: 31, Issue:2

    Topics: Chelating Agents; Female; Hepatolenticular Degeneration; Humans; Penicillamine; Pregnancy; Pregnancy

2000
Hepatolenticular degeneration (Wilson's disease) and pregnancy. A review and report of a case.
    Obstetrical & gynecological survey, 1977, Volume: 32, Issue:8

    Topics: Adolescent; Adult; Animals; Ceruloplasmin; Copper; Estrogens; Female; Fertility; Hepatolenticular De

1977
The use of gastrointestinal drugs during pregnancy and lactation.
    The American journal of gastroenterology, 1985, Volume: 80, Issue:11

    Topics: Adrenal Cortex Hormones; Animals; Antidiarrheals; Antiemetics; Cathartics; Diuretics; Female; Gastro

1985
[Current aspects of D-penicillamine and pregnancy].
    Zeitschrift fur Rheumatologie, 1988, Volume: 47 Suppl 1

    Topics: Abnormalities, Drug-Induced; Arthritis, Rheumatoid; Cystinuria; Female; Hepatolenticular Degeneratio

1988
Antirheumatic drug treatment during pregnancy and lactation.
    Scandinavian journal of rheumatology, 1985, Volume: 14, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Inflammatory Agents; Azathioprine; Chloroquine; Cyc

1985
Antirheumatic medication in pregnancy.
    British journal of rheumatology, 1985, Volume: 24, Issue:3

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Antineoplas

1985
Saturnism, pediatric and adult lead poisoning.
    Clinical toxicology, 1971, Volume: 4, Issue:1

    Topics: Adult; Central Nervous System Diseases; Chicago; Child; Child, Preschool; Edetic Acid; Environmental

1971

Other Studies

39 other studies available for penicillamine and Complications, Pregnancy

ArticleYear
Anesthetic management of cesarean delivery for a parturient with Wilson's disease: A case report.
    Medicine, 2018, Volume: 97, Issue:20

    Topics: Adult; Anesthetics, General; Cesarean Section; Chelating Agents; Female; Hepatolenticular Degenerati

2018
Transient fetal myelosuppressive effect of D-penicillamine when used in pregnancy.
    Minerva pediatrica, 2003, Volume: 55, Issue:6

    Topics: Chelating Agents; Female; Fetal Diseases; Hepatolenticular Degeneration; Humans; Infant, Newborn; Le

2003
Pregnancy and cystinuria.
    Lancet (London, England), 1983, Nov-19, Volume: 2, Issue:8360

    Topics: Birth Weight; Cystinuria; Female; Follow-Up Studies; Genetic Counseling; Humans; Penicillamine; Preg

1983
D-penicillamine in pregnancy--to ban or not to ban?
    Klinische Wochenschrift, 1981, Jun-01, Volume: 59, Issue:11

    Topics: Arthritis, Rheumatoid; Connective Tissue Diseases; Cystinuria; Female; Hepatolenticular Degeneration

1981
[Pregnancy and rheumatic disease (author's transl)].
    Ryumachi. [Rheumatism], 1981, Volume: 21, Issue:2

    Topics: Arthritis, Rheumatoid; Female; Gold; Humans; Penicillamine; Pregnancy; Pregnancy Complications; Scle

1981
[Wilson's disease: seven cases with hepatic onset (author's transl)].
    Medicina clinica, 1981, Nov-25, Volume: 77, Issue:9

    Topics: Adolescent; Adult; Child; Copper; Female; Hepatitis; Hepatolenticular Degeneration; Humans; Liver; L

1981
Wilson's disease in pregnancy.
    European journal of obstetrics, gynecology, and reproductive biology, 1995, Volume: 62, Issue:1

    Topics: Adolescent; Copper; Female; Hepatolenticular Degeneration; Humans; Liver; Male; Penicillamine; Pregn

1995
Pregnancy in a patient with Wilson's disease treated with D-penicillamine and zinc sulfate. A case report and review of the literature.
    European neurology, 1994, Volume: 34, Issue:6

    Topics: Adult; Female; Hepatolenticular Degeneration; Humans; Penicillamine; Pregnancy; Pregnancy Complicati

1994
Pregnancy alters cerebrovascular adaptation to high-altitude hypoxia.
    The American journal of physiology, 1994, Volume: 266, Issue:3 Pt 2

    Topics: Adaptation, Physiological; Altitude; Animals; Blood Vessels; Calcimycin; Cerebrovascular Circulation

1994
Copper disposition of the fetus and placenta in a patient with untreated Wilson's disease.
    American journal of obstetrics and gynecology, 1993, Volume: 169, Issue:1

    Topics: Adult; Ceruloplasmin; Copper; Female; Fetal Diseases; Fetus; Hepatolenticular Degeneration; Humans;

1993
Prenatal exposure to penicillamine and oral clefts: case report.
    American journal of medical genetics, 1998, Mar-19, Volume: 76, Issue:3

    Topics: Adult; Chelating Agents; Cleft Lip; Cleft Palate; Female; Hepatolenticular Degeneration; Humans; Inf

1998
Five successful deliveries following 9 consecutive spontaneous abortions in a patient with Wilson disease.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1998, Volume: 38, Issue:3

    Topics: Abortion, Habitual; Adult; Ceruloplasmin; Chelating Agents; Copper; Delivery, Obstetric; Female; Hep

1998
[Pregnancy, labor and early puerperium in a patient with Wilson's disease].
    Ceska gynekologie, 1999, Volume: 64, Issue:3

    Topics: Adult; Chelating Agents; Female; Foot Deformities, Congenital; Hepatolenticular Degeneration; Humans

1999
Acute hepatitis after starting zinc therapy in a patient with presymptomatic Wilson's disease.
    Hepatology (Baltimore, Md.), 2000, Volume: 32, Issue:4 Pt 1

    Topics: Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Female; Hepatolenticular Degeneration;

2000
Wilson's disease in pregnancy: five successful consecutive pregnancies of the same woman.
    European journal of obstetrics, gynecology, and reproductive biology, 2001, Volume: 96, Issue:2

    Topics: Alanine Transaminase; Apgar Score; Aspartate Aminotransferases; Chelating Agents; Female; Gestationa

2001
Letter: Mannosidosis and maternal penicillamine therapy.
    Lancet (London, England), 1976, Feb-07, Volume: 1, Issue:7954

    Topics: Carbohydrate Metabolism, Inborn Errors; Disaccharidases; Female; Hepatolenticular Degeneration; Huma

1976
Penicillamine in pregnancy.
    Lancet (London, England), 1978, Mar-18, Volume: 1, Issue:8064

    Topics: Drug Evaluation; Female; Humans; Penicillamine; Pregnancy; Pregnancy Complications

1978
Pregnancy and delivery in penicillamine treated patients with Wilson's disease.
    The Tohoku journal of experimental medicine, 1977, Volume: 123, Issue:3

    Topics: Adult; Copper; Female; Hepatolenticular Degeneration; Humans; Labor, Obstetric; Liver; Maternal-Feta

1977
[Problems of rheumatic therapy in pregnancy (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1976, Oct-08, Volume: 118, Issue:41

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Azathioprine; Chloroquine; Female; Fetal Diseases

1976
Pregnancy in Wilson's disease.
    The Quarterly journal of medicine, 1977, Volume: 46, Issue:181

    Topics: Ceruloplasmin; Copper; Female; Fetal Blood; Hepatolenticular Degeneration; Humans; Penicillamine; Pr

1977
The treatment of rheumatoid arthritis.
    Australian family physician, 1977, Volume: 6, Issue:8

    Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Child; Chloroquine; Female; Gold; Humans; Hydroxychl

1977
Letter: Pregnancy in penicillamine-treated patients with Wilson's disease.
    The New England journal of medicine, 1976, Oct-07, Volume: 295, Issue:15

    Topics: Female; Hepatolenticular Degeneration; Humans; Maternal-Fetal Exchange; Penicillamine; Pregnancy; Pr

1976
Pregnancy in penicillamine-treated patients with Wilson's disease.
    The New England journal of medicine, 1975, Dec-18, Volume: 293, Issue:25

    Topics: Adolescent; Adult; Female; Hepatolenticular Degeneration; Humans; Infant, Newborn; Male; Penicillami

1975
Letter: The pregnant woman with Wilson's disease.
    The New England journal of medicine, 1976, Mar-18, Volume: 294, Issue:12

    Topics: Female; Fetus; Hepatolenticular Degeneration; Humans; Maternal-Fetal Exchange; Penicillamine; Pregna

1976
Pregnancy and Wilson's disease.
    American journal of obstetrics and gynecology, 1991, Volume: 165, Issue:2

    Topics: Female; Hepatolenticular Degeneration; Humans; Penicillamine; Pregnancy; Pregnancy Complications; Su

1991
Pregnancy in a patient with treated Wilson's disease: a case report.
    American journal of obstetrics and gynecology, 1990, Volume: 163, Issue:5 Pt 1

    Topics: Adult; Female; Hepatolenticular Degeneration; Humans; Penicillamine; Pregnancy; Pregnancy Complicati

1990
Treatment of rheumatic diseases.
    British medical journal (Clinical research ed.), 1987, Jan-24, Volume: 294, Issue:6566

    Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Breast Feeding;

1987
[Hepatocerebral dystrophy in pregnancy].
    Akusherstvo i ginekologiia, 1988, Issue:10

    Topics: Adult; Female; Hepatolenticular Degeneration; Humans; Penicillamine; Pregnancy; Pregnancy Complicati

1988
Pregnancy and penicillamine treatment in a patient with Wilson's disease.
    Japanese journal of medicine, 1986, Volume: 25, Issue:1

    Topics: Adult; Ceruloplasmin; Female; Hepatolenticular Degeneration; Humans; Infant, Newborn; Male; Penicill

1986
Teratogen update: penicillamine.
    Teratology, 1986, Volume: 33, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Collagen; Copper; Cutis Laxa; Female; Hepatolenticular Degener

1986
Pregnancy and progressive systemic sclerosis. Case report and review of the literature.
    Cleveland Clinic quarterly, 1985,Summer, Volume: 52, Issue:2

    Topics: Adult; Blood Pressure; Colchicine; Female; Humans; Penicillamine; Prednisone; Pregnancy; Pregnancy C

1985
Successful pregnancy in Wilson's disease: a case report and review of the literature.
    European neurology, 1985, Volume: 24, Issue:5

    Topics: Adult; Ceruloplasmin; Copper; Diet; Female; Hepatolenticular Degeneration; Humans; Penicillamine; Pr

1985
Congenital connective-tissue defect probably due to D-penicillamine treatment in pregnancy.
    Lancet (London, England), 1971, Apr-03, Volume: 1, Issue:7701

    Topics: Collagen Diseases; Connective Tissue; Cystinuria; Elasticity; Female; Humans; Infant, Newborn; Infan

1971
D-penicillamine treatment in pregnancy.
    Lancet (London, England), 1971, May-15, Volume: 1, Issue:7707

    Topics: Adult; Cystinuria; Female; Humans; Penicillamine; Pregnancy; Pregnancy Complications

1971
[Pregnancy in a case of Wilson's copper metabolism disorder].
    Geburtshilfe und Frauenheilkunde, 1972, Volume: 32, Issue:7

    Topics: Amenorrhea; Female; Hepatolenticular Degeneration; Humans; Infertility; Male; Penicillamine; Pregnan

1972
Wilson's disease and pregnancy. A case report.
    Fertility and sterility, 1973, Volume: 24, Issue:6

    Topics: Abortion, Spontaneous; Adult; Ascites; Autopsy; Ceruloplasmin; Copper; Diet Therapy; Female; Fetus;

1973
[Treatment of chronic hepatitis].
    Zeitschrift fur arztliche Fortbildung, 1974, Volume: 68, Issue:5

    Topics: Azathioprine; Chronic Disease; Diet Therapy; Dietary Carbohydrates; Dietary Proteins; Female; Hepati

1974
Alkyl mercury poisoning in humans. Report of an outbreak.
    JAMA, 1972, Jun-12, Volume: 220, Issue:11

    Topics: Adolescent; Adult; Amniocentesis; Animal Feed; Ataxia; Cerebellum; Child; Child, Preschool; Coma; Di

1972
[Therapeutic problems during D-penicillamine treatment of patients with cystine calculi].
    Munchener medizinische Wochenschrift (1950), 1970, Nov-27, Volume: 112, Issue:48

    Topics: Adolescent; Adult; Albuminuria; Copper; Cystine; Cystinuria; Female; Humans; Kidney Calculi; Penicil

1970